Chronic morphine treatment impaired hippocampal long-term potentiation and spatial memory via accumulation of extracellular adenosine acting on adenosine A1 receptors

Journal of Neuroscience

Volumn 30, Issue 14, 2010, Pages 5058-5070

  Lu, Gang ^a   Zhou, Qi Xin ^b   Kang, Shuo ^a   Li, Qing Lin ^c   Zhao, Liang Cai ^c   Chen, Jia Dong ^d   Sun, Jian Feng ^a   Cao, Jun ^b   Wang, Yu Jun ^a   Chen, Jie ^a   Chen, Xiao Yan ^a   Zhong, Da Fang ^a   Chi, Zhi Qiang ^a   Xu, Lin ^b   Liu, Jing Gen ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c ANHUI UNIVERSITY OF CHINESE MEDICINE   (China)

^d INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE DEAMINASE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; MORPHINE; NALTREXONE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HIPPOCAMPUS; LONG TERM EXPOSURE; LONG TERM POTENTIATION; MALE; MEMORY DISORDER; MORPHINE ADDICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPATIAL MEMORY; TASK PERFORMANCE;

ADENOSINE; ANIMALS; DRUG ADMINISTRATION SCHEDULE; EXTRACELLULAR SPACE; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY; MICE; MORPHINE; RECEPTOR, ADENOSINE A1; SPATIAL BEHAVIOR;

EID: 77950609939     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0148-10.2010     Document Type: Article

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