Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

Nature Biotechnology

Volumn 31, Issue 4, 2013, Pages 342-349

  Gat Viks, Irit ^a,b   Chevrier, Nicolas ^a,c,d   Wilentzik, Roni ^b   Eisenhaure, Thomas ^a,e   Raychowdhury, Raktima ^a   Steuerman, Yael ^b   Shalek, Alex K ^f,g   Hacohen, Nir ^a,c,e   Amit, Ido ^a,h   Regev, Aviv ^a,i  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD UNIVERSITY   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f HARVARD UNIVERSITY   (United States)

^g HARVARD UNIVERSITY   (United States)

^h WEIZMANN INSTITUTE OF SCIENCE   (Israel)

ⁱ MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRAL RESPONSE; CONTROL RESPONSE; GENETIC VARIATION; MOLECULAR CIRCUITS; QUANTITATIVE TRAIT LOCUS; RECOMBINANT INBRED; RNA INTERFERENCE; TRANSCRIPTIONAL PROFILING;

PLANTS (BOTANY); RNA; VIRUSES;

GENES;

CIS ACTING ELEMENT; FAM129A PROTEIN; IKBKE PROTEIN; IVNS1ABP PROTEIN; PROTEIN; PTPRC PROTEIN; RGS16 PROTEIN; RNASEL PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLEIOTROPY; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RNA INTERFERENCE; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; STIMULUS RESPONSE; TRANSCRIPTION INITIATION; VIRUS IMMUNITY;

ANIMALS; CHROMOSOMES, MAMMALIAN; DENDRITIC CELLS; FEMALE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENETIC PLEIOTROPY; GENETIC VARIATION; MICE; MICE, INBRED STRAINS; QUANTITATIVE TRAIT LOCI; RGS PROTEINS; TOLL-LIKE RECEPTORS; TRANSCRIPTION, GENETIC;

EID: 84877266456     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2519     Document Type: Article

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