Interactions between glucocorticoid treatment and Cis-regulatory polymorphisms contribute to cellular response phenotypes

PLoS Genetics

Volumn 7, Issue 7, 2011, Pages

  Maranville, Joseph C ^a   Luca, Francesca ^a   Richards, Allison L ^a   Wen, Xiaoquan ^a   Witonsky, David B ^a   Baxter, Shaneen ^a   Stephens, Matthew ^a   Rienzo, Anna ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; INTERLEUKIN 6; AUTOIMMUNE REGULATOR PROTEIN; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; IMMEDIATE EARLY PROTEIN; NQO1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SERUM GLUCOCORTICOID REGULATED KINASE; SERUM-GLUCOCORTICOID REGULATED KINASE; TRANSCRIPTION FACTOR;

AFRICAN AMERICAN; ARTICLE; B LYMPHOCYTE ACTIVATION; CAUCASIAN; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CYTOKINE RELEASE; DNA POLYMORPHISM; DOWN REGULATION; EUROPEAN AMERICAN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; PHENOTYPE; PROTEIN SECRETION; TRANSCRIPTION REGULATION; UPREGULATION; B LYMPHOCYTE; CELL LINE; CYTOLOGY; DRUG EFFECT; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENETICS; GENOMICS; ITALY; METABOLISM; METHODOLOGY; NIGERIA; SECRETION;

HUMAN HERPESVIRUS 4;

B-LYMPHOCYTES; CELL LINE, TRANSFORMED; DEXAMETHASONE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOMICS; GLUCOCORTICOIDS; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERLEUKIN-6; ITALY; NAD(P)H DEHYDROGENASE (QUINONE); NIGERIA; POLYMORPHISM, GENETIC; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, GLUCOCORTICOID; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 79960967243     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002162     Document Type: Article

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