SPECT imaging of joint inflammation with nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis

Journal of Nuclear Medicine

Volumn 54, Issue 5, 2013, Pages 807-814

  Put, Stéphanie ^a   Schoonooghe, Steve ^b,c   Devoogdt, Nick ^b   Schurgers, Evelien ^a   Avau, Anneleen ^a   Mitera, Tania ^a   D'Huyvetter, Matthias ^b,d   De Baetselier, Patrick ^b,c   Raes, Geert ^b,c   Lahoutte, Tony ^b,e   Matthys, Patrick ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d BELGIAN NUCLEAR RESEARCH CENTRE   (Belgium)

^e UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

Collagen induced arthritis (CIA); Macrophage mannose receptor (MMR); Nanobody; Single photon emission computed tomography (SPECT)

Indexed keywords

ABCAM TC 99M; CD11B ANTIGEN; MACROPHAGE MANNOSE RECEPTOR; MEMBRANE RECEPTOR; NANOBODY; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE MARROW; BONE MARROW CELL; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED STUDY; GAMMA CAMERA; IMAGING SOFTWARE; IN VITRO STUDY; LABORATORY DEVICE; LYMPH NODE; MACROPHAGE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPECT SCANNER; SPLEEN; SYNOVIAL FLUID;

COLLAGEN-INDUCED ARTHRITIS (CIA); MACROPHAGE MANNOSE RECEPTOR (MMR); NANOBODY; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT);

ANIMALS; ARTHRITIS, RHEUMATOID; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; INFLAMMATION; LECTINS, C-TYPE; MACROPHAGES; MALE; MANNOSE-BINDING LECTINS; MICE; ORGANOTECHNETIUM COMPOUNDS; OSTEOCLASTS; RECEPTORS, CELL SURFACE; SINGLE-DOMAIN ANTIBODIES; SYNOVIAL MEMBRANE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84877146779     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.112.111781     Document Type: Article

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