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Volumn 25, Issue 7, 2011, Pages 2433-2446

Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer

Author keywords

SPECT; Tracer development

Indexed keywords

ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; NANOBODY; PERTUZUMAB; RADIOLIGAND; TECHNETIUM 99M; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 79960188481     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-180331     Document Type: Article
Times cited : (252)

References (34)
  • 1
    • 16244403039 scopus 로고    scopus 로고
    • Cancer incidence and mortality in Europe, 2004
    • DOI 10.1093/annonc/mdi098
    • Boyle, P. and Ferlay, J. (2005) Cancer incidence and mortality in Europe, 2004. Annals Oncol. 16, 481-488 (Pubitemid 40458328)
    • (2005) Annals of Oncology , vol.16 , Issue.3 , pp. 481-488
    • Boyle, P.1    Ferlay, J.2
  • 3
    • 0034766736 scopus 로고    scopus 로고
    • Biology of HER2 and its importance in breast cancer
    • Yarden, Y. (2001) Biology of HER2 and its importance in breast cancer. Oncology 61(Suppl 2), 1-13
    • (2001) Oncology , vol.61 , Issue.SUPPL. 2 , pp. 1-13
    • Yarden, Y.1
  • 4
    • 40449087743 scopus 로고    scopus 로고
    • HER2+ breast cancer: Review of biologic relevance and optimal use of diagnostic tools
    • DOI 10.1309/99AE032R9FM8WND1
    • Hicks, D. G., and Kulkarni, S. (2008) HER2+ breast cancer: review of biologic relevance and optimal use of diagnostic tools. Am. J. Clin. Pathol. 129, 263-273 (Pubitemid 352029317)
    • (2008) American Journal of Clinical Pathology , vol.129 , Issue.2 , pp. 263-273
    • Hicks, D.G.1    Kulkarni, S.2
  • 6
    • 26944465031 scopus 로고    scopus 로고
    • Comparison of HER-2 overexpression in primary breast cancer and metastatic sites and its effect on biological targeting therapy of metastatic disease
    • DOI 10.1038/sj.bjc.6602738, PII 6602738
    • Zidan, J., Dashkovsky, I., Stayerman, C., Basher, W., Cozacov, C., and Hadary, A. (2005) Comparison of HER-2 overexpression in primary breast cancer and metastatic sites and its effect on biological targeting therapy of metastatic disease. Brit. J. Cancer 93, 552-556 (Pubitemid 43079998)
    • (2005) British Journal of Cancer , vol.93 , Issue.5 , pp. 552-556
    • Zidan, J.1    Dashkovsky, I.2    Stayerman, C.3    Basher, W.4    Cozacov, C.5    Hadary, A.6
  • 8
    • 33847165329 scopus 로고    scopus 로고
    • Intratumoral heterogeneity of HER2/neu in breast cancer - A rare event
    • DOI 10.1111/j.1524-4741.2007.00396.x
    • Hanna, W., Nofech-Mozes, S., and Kahn, H. J. (2007) Intratumoral heterogeneity of HER2/neu in breast cancer - a rare event. Breast J. 13, 122-129 (Pubitemid 46280606)
    • (2007) Breast Journal , vol.13 , Issue.2 , pp. 122-129
    • Hanna, W.1    Nofech-Mozes, S.2    Kahn, H.J.3
  • 9
    • 58149095508 scopus 로고    scopus 로고
    • Imaging of HER-2 overexpression in tumors for guiding therapy
    • Tolmachev, V. (2008) Imaging of HER-2 overexpression in tumors for guiding therapy. Curr. Pharm. Des. 14, 2999-3019
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 2999-3019
    • Tolmachev, V.1
  • 10
    • 0008331304 scopus 로고    scopus 로고
    • Does immunoscintigraphy allow for prognostic predictions with respect to the toxicity and therapeutic efficacy of herceptin immunotherapy of metastatic breast cancer?
    • Behr, T. M., Behe, M., Angerstein, C., Griesinger, F., Kaufmann, C. C., Wörmann, B., Emons, G., and Becker, W. (2001) Does immunoscintigraphy allow for prognostic predictions with respect to the toxicity and therapeutic efficacy of herceptin immunotherapy of metastatic breast cancer? Eur. J. Nucl. Med. 28, 976
    • (2001) Eur. J. Nucl. Med. , vol.28 , pp. 976
    • Behr, T.M.1    Behe, M.2    Angerstein, C.3    Griesinger, F.4    Kaufmann, C.C.5    Wörmann, B.6    Emons, G.7    Becker, W.8
  • 12
    • 0033571383 scopus 로고    scopus 로고
    • High thermal stability is essential for tumor targeting of antibody fragments: Engineering of a humanized antiepithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment
    • Willuda, J., Honegger, A., Waibel, R., Schubiger, P. A., Stahel, R., Zangemeister-Wittke, U., and Plückthun, A. (1999) High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized antiepithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment. Cancer Res. 59, 5758-5767
    • (1999) Cancer Res. , vol.59 , pp. 5758-5767
    • Willuda, J.1    Honegger, A.2    Waibel, R.3    Schubiger, P.A.4    Stahel, R.5    Zangemeister-Wittke, U.6    Plückthun, A.7
  • 19
    • 0030767656 scopus 로고    scopus 로고
    • Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
    • DOI 10.1016/S0014-5793(97)01062-4, PII S0014579397010624
    • Arbabi Ghahroudi, M., Desmyter, A., Wyns, L., Hamers, R., and Muyldermans, S. (1997) Selection and identification of single domain antibody fragments from camel heavy-chain antibodies. FEBS Lett. 414, 521-526 (Pubitemid 27390659)
    • (1997) FEBS Letters , vol.414 , Issue.3 , pp. 521-526
    • Arbabi, G.M.1    Desmyter, A.2    Wyns, L.3    Hamers, R.4    Muyldermans, S.5
  • 20
    • 24044472050 scopus 로고    scopus 로고
    • Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
    • DOI 10.1016/j.jmb.2005.07.038, PII S0022283605008260
    • Saerens, D., Pellis, M., Loris. R., Pardon E, Dumoulin, M., Matagne, A., Wyns, L., Muyldermans, S., and Conrath, K. (2005) Identification of a universal VHH framework to graft noncanonical antigen-binding loops of camel single-domain antibodies. J. Mol. Biol. 352, 597-607 (Pubitemid 41225471)
    • (2005) Journal of Molecular Biology , vol.352 , Issue.3 , pp. 597-607
    • Saerens, D.1    Pellis, M.2    Loris, R.3    Pardon, E.4    Dumoulin, M.5    Matagne, A.6    Wyns, L.7    Muyldermans, S.8    Conrath, K.9
  • 21
    • 59149104037 scopus 로고    scopus 로고
    • General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold
    • Vincke, C., Loris, R., Saerens, D., Martinez-Rodriguez, S., Muyldermans, S., and Conrath, K. (2009) General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. J. Biol. Chem. 284, 3273-3284
    • (2009) J. Biol. Chem. , vol.284 , pp. 3273-3284
    • Vincke, C.1    Loris, R.2    Saerens, D.3    Martinez-Rodriguez, S.4    Muyldermans, S.5    Conrath, K.6
  • 22
    • 70350714454 scopus 로고    scopus 로고
    • 18F-FDG small-animal PET/CT differentiates trastuzumab-responsive from unresponsive human breast cancer xenografts in athymic mice
    • McLarty, K., Fasih, A., Scollard, D. A., Done, S. J., Vines, D. C., Green, D. E., Costantini, D. L., and Reilly, R. M. (2009) 18F-FDG small-animal PET/CT differentiates trastuzumab-responsive from unresponsive human breast cancer xenografts in athymic mice. J. Nucl. Med. 50, 1848-1856
    • (2009) J. Nucl. Med. , vol.50 , pp. 1848-1856
    • McLarty, K.1    Fasih, A.2    Scollard, D.A.3    Done, S.J.4    Vines, D.C.5    Green, D.E.6    Costantini, D.L.7    Reilly, R.M.8
  • 23
    • 18144416577 scopus 로고    scopus 로고
    • Imaging of HER2/neu expression in BT-474 human breast cancer xenografts in athymic mice using [(99m)Tc]-HYNIC-trastuzumab (herceptin) Fab fragments
    • Tang, Y., Scollard, D., Chen, P., Wang, J., Holloway, C., and Reilly, R. M. (2005) Imaging of HER2/neu expression in BT-474 human breast cancer xenografts in athymic mice using [(99m)Tc]-HYNIC-trastuzumab (herceptin) Fab fragments. Nucl. Med. Commun. 26, 427-432
    • (2005) Nucl. Med. Commun. , vol.26 , pp. 427-432
    • Tang, Y.1    Scollard, D.2    Chen, P.3    Wang, J.4    Holloway, C.5    Reilly, R.M.6
  • 24
    • 0033708769 scopus 로고    scopus 로고
    • Targeting of bivalent anti-ErbB2 diabody antibody fragments to tumor cells is independent of the intrinsic antibody affinity
    • Nielsen, U. B., Adams, G. P., Weiner, L. M., and Marks, J. D. (2000) Targeting of bivalent anti-ErbB2 diabody antibody fragments to tumor cells is independent of the intrinsic antibody affinity. Cancer Res. 60, 6434-6440
    • (2000) Cancer Res. , vol.60 , pp. 6434-6440
    • Nielsen, U.B.1    Adams, G.P.2    Weiner, L.M.3    Marks, J.D.4
  • 25
    • 13944266719 scopus 로고    scopus 로고
    • Quantitative immuno-positron emission tomography imaging of HER2-positlve tumor xenografts with an iodine-124 labeled anti-HER2 diabody
    • DOI 10.1158/0008-5472.CAN-04-2008
    • Robinson, M. K., Doss, M., Shaller, C., Narayanan, D., Marks, J. D., Adler, L. P., González Trotter, D. E., and Adams, G. P. (2005) Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody. Cancer Res. 65, 1471-1478 (Pubitemid 40270176)
    • (2005) Cancer Research , vol.65 , Issue.4 , pp. 1471-1478
    • Robinson, M.K.1    Doss, M.2    Shaller, C.3    Narayanan, D.4    Marks, J.D.5    Adler, L.P.6    Gonzalez, T.D.E.7    Adams, G.P.8
  • 29
    • 35348819390 scopus 로고    scopus 로고
    • Properties, production, and applications of camelid single-domain antibody fragments
    • DOI 10.1007/s00253-007-1142-2
    • Harmsen, M. M., and De Haard, H. J. (2007) Properties, production, and applications of camelid single-domain antibody fragments. Appl. Microbiol. Biotechnol. 77, 13-22 (Pubitemid 47573319)
    • (2007) Applied Microbiology and Biotechnology , vol.77 , Issue.1 , pp. 13-22
    • Harmsen, M.M.1    De Haard, H.J.2
  • 30
    • 79954991349 scopus 로고    scopus 로고
    • Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice
    • E-pub ahead of print doi: 10.1002/cmmi.408
    • Gainkam, L. O. T., Caveliers, V., Devoogdt, N., Vanhove, C., Xavier, C., Boerman, O., Muyldermans, S., Bossuyt, A., and Lahoutte, T. (2010) Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice. [E-pub ahead of print] Contrast Media Mol. Imaging doi: 10.1002/cmmi.408
    • (2010) Contrast Media Mol. Imaging
    • Gainkam, L.O.T.1    Caveliers, V.2    Devoogdt, N.3    Vanhove, C.4    Xavier, C.5    Boerman, O.6    Muyldermans, S.7    Bossuyt, A.8    Lahoutte, T.9
  • 32
    • 33845939857 scopus 로고    scopus 로고
    • Selection and characterization of Her2 binding-designed ankyrin repeat proteins
    • DOI 10.1074/jbc.M602547200
    • Zahnd, C., Pecorari, F., Straumann, N., Wyler, E., and Plückthun, A. (2006) Selection and characterization of Her2 bindingdesigned ankyrin repeat proteins. J. Biol. Chem. 281, 35167-35175 (Pubitemid 46036556)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.46 , pp. 35167-35175
    • Zahnd, C.1    Pecorari, F.2    Straumann, N.3    Wyler, E.4    Pluckthun, A.5
  • 34
    • 77954966119 scopus 로고    scopus 로고
    • Renal toxicity of radiolabeled peptides and antibody fragments: Mechanisms, impact on radionuclide therapy, and strategies for prevention
    • Vegt, E., de Jong, M., Wetzels, J. F., Masereeuw, R., Melis, M., Oyen, W. J., Gotthardt, M., Boerman, O. C. (2010) Renal toxicity of radiolabeled peptides and antibody fragments: mechanisms, impact on radionuclide therapy, and strategies for prevention. J. Nucl. Med. 51, 1049-1058
    • (2010) J. Nucl. Med. , vol.51 , pp. 1049-1058
    • Vegt, E.1    De Jong, M.2    Wetzels, J.F.3    Masereeuw, R.4    Melis, M.5    Oyen, W.J.6    Gotthardt, M.7    Boerman, O.C.8


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