-
1
-
-
40749150603
-
Acute lymphoblastic leukaemia
-
Pui CH, Robison LL, Look AT. Acute lymphoblastic leukaemia. Lancet 2008 ; 371 : 1030-1043
-
(2008)
Lancet
, vol.371
, pp. 1030-1043
-
-
Pui, C.H.1
Robison, L.L.2
Look, A.T.3
-
2
-
-
0142126194
-
Gene expression profi ling in T-cell acute lymphoblastic leukemia
-
Ferrando AA, Look AT. Gene expression profi ling in T-cell acute lymphoblastic leukemia. Semin Hematol 2003; 40: 274-280
-
(2003)
Semin Hematol
, vol.40
, pp. 274-280
-
-
Ferrando, A.A.1
Look, A.T.2
-
3
-
-
33646366173
-
Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
-
Grabher C, von Boehmer H, Look A T. Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. Nat Rev Cancer 2006; 6: 347-359
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 347-359
-
-
Grabher, C.1
Von Boehmer, H.2
Look, A.T.3
-
4
-
-
34548589669
-
Identifi cation of genomic classifi ers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: A report from the children s oncology group
-
Winter SS, Jiang Z, Khawaja HM, et al. Identifi cation of genomic classifi ers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: A report from the children s oncology group. Blood 2007 ; 110 : 1429-1438
-
(2007)
Blood
, vol.110
, pp. 1429-1438
-
-
Winter, S.S.1
Jiang, Z.2
Khawaja, H.M.3
-
5
-
-
34249676963
-
Microarray-based classifi cation of a consecutive series of 121 childhood acute leukemias: Prediction of leukemic and genetic subtype as well as of minimal residual disease status
-
Andersson A, Ritz C, Lindgren D, et al. Microarray-based classifi cation of a consecutive series of 121 childhood acute leukemias: Prediction of leukemic and genetic subtype as well as of minimal residual disease status. Leukemia 2007 ; 21 : 1198-1203
-
(2007)
Leukemia
, vol.21
, pp. 1198-1203
-
-
Andersson, A.1
Ritz, C.2
Lindgren, D.3
-
6
-
-
79953735093
-
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia
-
Homminga I, Pieters R, Langerak AW, et al. Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia. Cancer Cell 2011 ; 19 : 484-497
-
(2011)
Cancer Cell
, vol.19
, pp. 484-497
-
-
Homminga, I.1
Pieters, R.2
Langerak, A.W.3
-
7
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
Zhang J, Ding L, Holmfeldt L, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 2012; 481: 157-163
-
(2012)
Nature
, vol.481
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
-
8
-
-
78649516513
-
Genetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia
-
Meijerink J P. Genetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia. Best Pract Res Clin Haematol 2010 ; 23 : 307-318
-
(2010)
Best Pract Res Clin Haematol
, vol.23
, pp. 307-318
-
-
Meijerink, J.P.1
-
9
-
-
0037071399
-
Tumor suppressor genes in normal and malignant hematopoiesis
-
Krug U, Ganser A, Koeffler HP. Tumor suppressor genes in normal and malignant hematopoiesis. Oncogene 2002 ; 21 : 3475-3495
-
(2002)
Oncogene
, vol.21
, pp. 3475-3495
-
-
Krug, U.1
Ganser, A.2
Koeffler, H.P.3
-
10
-
-
0037309326
-
Tumor suppression by Ink4a-Arf: Progress and puzzles
-
Lowe SW, Sherr CJ. Tumor suppression by Ink4a-Arf: Progress and puzzles. Curr Opin Genet Dev 2003; 13: 77-83
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 77-83
-
-
Lowe, S.W.1
Sherr, C.J.2
-
11
-
-
5444243390
-
Antagonism of myc functions by arf
-
Cleveland J L, Sherr C J. Antagonism of myc functions by arf. Cancer Cell 2004 ; 6 : 309-311
-
(2004)
Cancer Cell
, vol.6
, pp. 309-311
-
-
Cleveland, J.L.1
Sherr, C.J.2
-
12
-
-
0030941813
-
Homozygous deletion of the p16/MTS1 gene in pediatric acute lymphoblastic leukemia is associated withunfavorable clinical outcome
-
Kees UR, Burton PR, Lu C, et al. Homozygous deletion of the p16/MTS1 gene in pediatric acute lymphoblastic leukemia is associated withunfavorable clinical outcome. Blood 1997 ; 89 : 4161-4166
-
(1997)
Blood
, vol.89
, pp. 4161-4166
-
-
Kees, U.R.1
Burton, P.R.2
Lu, C.3
-
13
-
-
0030941174
-
Incidence and clinical signifi cance of CDKN2/MTS1/P16ink4A and MTS2/P15ink4B gene deletions in childhood acute lymphoblastic leukemia
-
Zhou M, Gu L, Yeager AM, et al. Incidence and clinical signifi cance of CDKN2/MTS1/P16ink4A and MTS2/P15ink4B gene deletions in childhood acute lymphoblastic leukemia. Pediatr Hematol Oncol 1997 ; 14 : 141-150
-
(1997)
Pediatr Hematol Oncol
, vol.14
, pp. 141-150
-
-
Zhou, M.1
Gu, L.2
Yeager, A.M.3
-
14
-
-
0035904395
-
Molecular biology of HMGA proteins: Hubs of nuclear function
-
Reeves R. Molecular biology of HMGA proteins: Hubs of nuclear function. Gene 2001 ; 277 : 63-81
-
(2001)
Gene
, vol.277
, pp. 63-81
-
-
Reeves, R.1
-
15
-
-
36448992338
-
Roles of HMGA proteins in cancer
-
Fusco A, Fedele M. Roles of HMGA proteins in cancer. Nat Rev Cancer 2007 ; 7 : 899-910
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 899-910
-
-
Fusco, A.1
Fedele, M.2
-
16
-
-
76549100402
-
The high mobility group A1 gene: Transforming inflammatory signals into cancer
-
Resar LM. The high mobility group A1 gene: Transforming inflammatory signals into cancer? Cancer Res 2010; 70: 436-439
-
(2010)
Cancer Res
, vol.70
, pp. 436-439
-
-
Resar, L.M.1
-
17
-
-
84859306174
-
High mobility group A1 and cancer: Potential biomarker and therapeutic target
-
Shah SN, Resar LM. High mobility group A1 and cancer: Potential biomarker and therapeutic target. Histol Histopathol 2012 ; 27 : 567-579
-
(2012)
Histol Histopathol
, vol.27
, pp. 567-579
-
-
Shah, S.N.1
Resar, L.M.2
-
18
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008 ; 40 : 499-507
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
-
19
-
-
79952536226
-
Effi cient human iPS cell derivation by a non-integrating plasmid from blood cells withunique epigenetic and gene expression signatures
-
Chou BK, Mali P, Huang X, et al. Effi cient human iPS cell derivation by a non-integrating plasmid from blood cells withunique epigenetic and gene expression signatures. Cell Res 2011; 21: 518-529
-
(2011)
Cell Res
, vol.21
, pp. 518-529
-
-
Chou, B.K.1
Mali, P.2
Huang, X.3
-
20
-
-
0035923689
-
The pattern of gene expression in human CD34 (-) stem/progenitor cells
-
Zhou G, Chen J, Lee S, et a l. The pattern of gene expression in human CD34 (-) stem/progenitor cells. Proc Natl Acad Sci USA 2001 ; 98 : 13966-13971
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13966-13971
-
-
Zhou, G.1
Chen, J.2
Lee, S.3
-
21
-
-
79953126542
-
Phase 1 and pharmacokinetic study of bolus-infusion fl avopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias
-
Karp JE, Smith BD, Resar LS, et al. Phase 1 and pharmacokinetic study of bolus-infusion fl avopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias. Blood 2011 ; 117 : 3302-3310
-
(2011)
Blood
, vol.117
, pp. 3302-3310
-
-
Karp, J.E.1
Smith, B.D.2
Resar, L.S.3
-
22
-
-
80053211500
-
Flavopiridol induces BCL-2 expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia
-
Nelson DM, Joseph B, Hillion J, et al. Flavopiridol induces BCL-2 expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia. Leuk Lymphoma 2011; 52: 1999-2006
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 1999-2006
-
-
Nelson, D.M.1
Joseph, B.2
Hillion, J.3
-
23
-
-
58949102947
-
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared wiThembryonic rather than adult stem cells
-
Somervaille T C, Matheny C J, Spencer G J, et a l. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared wiThembryonic rather than adult stem cells. Cell Stem Cell 2009 ; 4 : 129-140
-
(2009)
Cell Stem Cell
, vol.4
, pp. 129-140
-
-
Somervaille, T.C.1
Matheny, C.J.2
Spencer, G.J.3
-
24
-
-
0033912537
-
HMG-I/Y, anew c-myc target gene and potential oncogene
-
Wood LJ, Mukherjee M, Dolde CE, et al. HMG-I/Y, anew c-myc target gene and potential oncogene. Mol Cell Biol 2000 ; 20 : 5490-5502
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5490-5502
-
-
Wood, L.J.1
Mukherjee, M.2
Dolde, C.E.3
-
25
-
-
0033881018
-
The oncogenic properties of the HMG-I gene family
-
Wood LJ, Maher JF, Bunton TE, et al. The oncogenic properties of the HMG-I gene family. Cancer Res 2000 ; 60 : 4256-4261
-
(2000)
Cancer Res
, vol.60
, pp. 4256-4261
-
-
Wood, L.J.1
Maher, J.F.2
Bunton, T.E.3
-
27
-
-
2442668067
-
The HMG-I oncogene causes highly penetrant, aggressive lymphoid malignancy in transgenic mice and is overexpressed in human leukemia
-
Xu Y, Sumter TF, Bhattacharya R, et al. The HMG-I oncogene causes highly penetrant, aggressive lymphoid malignancy in transgenic mice and is overexpressed in human leukemia. Cancer Res 2004 ; 64 : 3371-3375
-
(2004)
Cancer Res
, vol.64
, pp. 3371-3375
-
-
Xu, Y.1
Sumter, T.F.2
Bhattacharya, R.3
-
28
-
-
34249279180
-
The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis
-
Tesfaye A, Di Cello F, Hillion J, et a l. The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis. Cancer Res 2007; 67: 3998-4004
-
(2007)
Cancer Res
, vol.67
, pp. 3998-4004
-
-
Tesfaye, A.1
Di Cello, F.2
Hillion, J.3
-
29
-
-
51049103668
-
HMGA2 participates in transformation in human lung cancer
-
Di Cello F, Hillion J, Hristov A, et al. HMGA2 participates in transformation in human lung cancer. Mol Cancer Res 2008 ; 6 : 743-750
-
(2008)
Mol Cancer Res
, vol.6
, pp. 743-750
-
-
Di Cello, F.1
Hillion, J.2
Hristov, A.3
-
30
-
-
51049109679
-
Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts
-
Di Cello F, Hillion J, Kowalski J, et al. Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts. Mol Cancer Ther 2008 ; 7 : 2090-2095
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2090-2095
-
-
Di Cello, F.1
Hillion, J.2
Kowalski, J.3
-
31
-
-
57749115895
-
The high-mobility group A1a/ signal transducer and activator of transcription-3 axis: An achilles heel for hematopoietic malignancies
-
Hillion J, Dhara S, Sumter TF, et al. The high-mobility group A1a/ signal transducer and activator of transcription-3 axis: An achilles heel for hematopoietic malignancies? Cancer Res 2008; 68: 10121-10127
-
(2008)
Cancer Res
, vol.68
, pp. 10121-10127
-
-
Hillion, J.1
Dhara, S.2
Sumter, T.F.3
-
32
-
-
72449176495
-
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer
-
Hillion J, Wood LJ, Mukherjee M, et al. Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer. Mol Cancer Res 2009; 7: 1803-1812
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1803-1812
-
-
Hillion, J.1
Wood, L.J.2
Mukherjee, M.3
-
33
-
-
58149148165
-
HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma
-
Hristov AC, Cope L, Reyes MD, et al. HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma. Mod Pathol 2009; 22: 43-49
-
(2009)
Mod Pathol
, vol.22
, pp. 43-49
-
-
Hristov, A.C.1
Cope, L.2
Reyes, M.D.3
-
34
-
-
73949132030
-
HMGA1 correlates withadvanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma
-
Hristov AC, Cope L, Di Cello F, et al. HMGA1 correlates withadvanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma. Mod Pathol 2010; 23: 98-104
-
(2010)
Mod Pathol
, vol.23
, pp. 98-104
-
-
Hristov, A.C.1
Cope, L.2
Di Cello, F.3
-
35
-
-
80355125228
-
HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis
-
Schuldenfrei A, Belton A, Kowalski J, et a l. HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis. BMC Genomics 2011; 12: 549
-
(2011)
BMC Genomics
, vol.12
, pp. 549
-
-
Schuldenfrei, A.1
Belton, A.2
Kowalski, J.3
-
36
-
-
84856055494
-
HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells
-
Belton A, Gabrovsky A, Bae YK, et al. HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells. PLoS One 2012; 7 : E30034
-
(2012)
PLoS One
, vol.7
-
-
Belton, A.1
Gabrovsky, A.2
Bae, Y.K.3
-
37
-
-
0037165140
-
Prediction of central nervous system embryonal tumour outcome based on gene expression
-
Pomeroy SL, Tamayo P, Gaasenbeek M, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 2002 ; 415 : 436-442
-
(2002)
Nature
, vol.415
, pp. 436-442
-
-
Pomeroy, S.L.1
Tamayo, P.2
Gaasenbeek, M.3
-
38
-
-
19944420447
-
Transgenic mice overexpressing the wild-Type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas
-
Fedele M, Pentimalli F, Baldassarre G, et al. Transgenic mice overexpressing the wild-Type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas. Oncogene 2005 ; 24 : 3427-3435
-
(2005)
Oncogene
, vol.24
, pp. 3427-3435
-
-
Fedele, M.1
Pentimalli, F.2
Baldassarre, G.3
-
39
-
-
0042704717
-
Loss of Hmga1 gene function aff ects embryonic stem cell lympho-hematopoietic differentiation
-
Battista S, Pentimalli F, Baldassarre G, et a l. Loss of Hmga1 gene function aff ects embryonic stem cell lympho-hematopoietic differentiation. FASEB J 2003 ; 17 : 1496-1498
-
(2003)
FASEB J
, vol.17
, pp. 1496-1498
-
-
Battista, S.1
Pentimalli, F.2
Baldassarre, G.3
-
40
-
-
33645052445
-
Haploinsuffi ciency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice
-
Fedele M, Fidanza V, Battista S, et al. Haploinsuffi ciency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice. Cancer Res 2006; 66: 2536-2543
-
(2006)
Cancer Res
, vol.66
, pp. 2536-2543
-
-
Fedele, M.1
Fidanza, V.2
Battista, S.3
-
41
-
-
79958017228
-
3 'UTR-Truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growthadvantage at the level of HSC in mice
-
Ikeda K, Mason P J, Bessler M. 3 'UTR-Truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growthadvantage at the level of HSC in mice. Blood 2011; 117: 5860-5869
-
(2011)
Blood
, vol.117
, pp. 5860-5869
-
-
Ikeda, K.1
Mason, P.J.2
Bessler, M.3
-
42
-
-
79957975768
-
Leting go with clonal expansion
-
Resar LM, Brodsky RA. " Let " -ing go with clonal expansion? Blood 2011;117:5788-5790
-
(2011)
Blood
, vol.117
, pp. 5788-5790
-
-
Resar, L.M.1
Brodsky, R.A.2
-
43
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
Serrano M, Lee H, Chin L, et a l. Role of the INK4a locus in tumor suppression and cell mortality. Cell 1996 ; 85 : 27-37
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.2
Chin, L.3
-
44
-
-
0036660203
-
Bethesda proposals for classifi cation of lymphoid neoplasms in mice
-
Morse HC 3rd, Anver MR, Fredrickson TN, et al. Bethesda proposals for classifi cation of lymphoid neoplasms in mice. Blood 2002 ; 100 : 246-258
-
(2002)
Blood
, vol.100
, pp. 246-258
-
-
Morse III, H.C.1
Anver, M.R.2
Fredrickson, T.N.3
-
45
-
-
0031025368
-
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies
-
Herman J G, Civin C I, Issa J P, et a l. Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies. Cancer Res 1997; 57: 837-841
-
(1997)
Cancer Res
, vol.57
, pp. 837-841
-
-
Herman, J.G.1
Civin, C.I.2
Issa, J.P.3
-
46
-
-
77449149374
-
Multicenter, phase II study of decitabine for the first-line treatment of older patients withacute myeloid leukemia
-
Cashen AF, Schiller GJ, O Donnell MR, et al. Multicenter, phase II study of decitabine for the first-line treatment of older patients withacute myeloid leukemia. J Clin Oncol 2010 ; 28 : 556-561
-
(2010)
J Clin Oncol
, vol.28
, pp. 556-561
-
-
Cashen, A.F.1
Schiller, G.J.2
O'Donnell, M.R.3
-
47
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated withaccumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, et al. Oncogenic ras provokes premature cell senescence associated withaccumulation of p53 and p16INK4a. Cell 1997 ; 88 : 593-602
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
-
48
-
-
79953655080
-
Recent advances in the therapeutic perspectives of nutlin-3
-
Secchiero P, Bosco R, Celeghini C, et al. Recent advances in the therapeutic perspectives of nutlin-3. Curr Pharm Des 2011; 17: 569-577
-
(2011)
Curr Pharm Des
, vol.17
, pp. 569-577
-
-
Secchiero, P.1
Bosco, R.2
Celeghini, C.3
-
49
-
-
84862776920
-
Reverse engineering of TLX oncogenic transcriptional networks identifi es RUNX1 as tumor suppressor in T-ALL
-
Della Gatta G, Palomero T, Perez-Garcia A, et al. Reverse engineering of TLX oncogenic transcriptional networks identifi es RUNX1 as tumor suppressor in T-ALL. Nat Med 2012 ; 18 : 436-440
-
(2012)
Nat Med
, vol.18
, pp. 436-440
-
-
Della Gatta, G.1
Palomero, T.2
Perez-Garcia, A.3
-
50
-
-
84869203467
-
HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks
-
Shah S N, Kerr C, Cope L, et a l. HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks. PLoS One 2012; 7 : E48533
-
(2012)
PLoS One
, vol.7
-
-
Shah, S.N.1
Kerr, C.2
Cope, L.3
-
51
-
-
84866491602
-
The HMGA1-COX-2 axis: A key molecular pathway and potential target in pancreatic adenocarcinoma
-
Hillion J, Smail SS, Di Cello F, et al. The HMGA1-COX-2 axis: A key molecular pathway and potential target in pancreatic adenocarcinoma. Pancreatology 2012 ; 12 : 372-379
-
(2012)
Pancreatology
, vol.12
, pp. 372-379
-
-
Hillion, J.1
Smail, S.S.2
Di Cello, F.3
-
52
-
-
0033772880
-
F R900482 class of anti-Tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo
-
Beckerbauer L, Tepe J J, Cullison J, et a l. F R900482 class of anti-Tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo. Chem Biol 2000 ; 7 : 805-812
-
(2000)
Chem Biol
, vol.7
, pp. 805-812
-
-
Beckerbauer, L.1
Tepe, J.J.2
Cullison, J.3
|