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Volumn 7, Issue 11, 2012, Pages

HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR SOX2;

EID: 84869203467     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048533     Document Type: Article
Times cited : (80)

References (69)
  • 1
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5
  • 3
    • 54949092372 scopus 로고    scopus 로고
    • From fibroblasts to iPS cells: Induced pluripotency by defined factors
    • Zhao R, Daley GQ, (2008) From fibroblasts to iPS cells: Induced pluripotency by defined factors. Journal of Cellular Biochemistry 105: 949-955.
    • (2008) Journal of Cellular Biochemistry , vol.105 , pp. 949-955
    • Zhao, R.1    Daley, G.Q.2
  • 5
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, et al. (2008) Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26: 101-106.
    • (2008) Nat Biotechnol , vol.26 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3    Takahashi, K.4    Ichisaka, T.5
  • 6
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park IH, Zhao R, West JA, Yabuuchi A, Huo H, et al. (2008) Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451: 141-146.
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3    Yabuuchi, A.4    Huo, H.5
  • 7
    • 79953881831 scopus 로고    scopus 로고
    • Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
    • Anokye-Danso F, Trivedi CM, Juhr D, Gupta M, Cui Z, et al. (2011) Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8: 376-388.
    • (2011) Cell Stem Cell , vol.8 , pp. 376-388
    • Anokye-Danso, F.1    Trivedi, C.M.2    Juhr, D.3    Gupta, M.4    Cui, Z.5
  • 8
    • 79551677421 scopus 로고    scopus 로고
    • Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
    • Bock C, Kiskinis E, Verstappen G, Gu H, Boulting G, et al. (2011) Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell 144: 439-452.
    • (2011) Cell , vol.144 , pp. 439-452
    • Bock, C.1    Kiskinis, E.2    Verstappen, G.3    Gu, H.4    Boulting, G.5
  • 9
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, et al. (2008) An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 40: 499-507.
    • (2008) Nat Genet , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5
  • 10
    • 48749109906 scopus 로고    scopus 로고
    • Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts
    • Mali P, Ye Z, Hommond HH, Yu X, Lin J, et al. (2008) Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells 26: 1998-2005.
    • (2008) Stem Cells , vol.26 , pp. 1998-2005
    • Mali, P.1    Ye, Z.2    Hommond, H.H.3    Yu, X.4    Lin, J.5
  • 11
    • 77950965653 scopus 로고    scopus 로고
    • Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes
    • Mali P, Chou BK, Yen J, Ye Z, Zou J, et al. (2010) Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells 28: 713-720.
    • (2010) Stem Cells , vol.28 , pp. 713-720
    • Mali, P.1    Chou, B.K.2    Yen, J.3    Ye, Z.4    Zou, J.5
  • 12
    • 77957365009 scopus 로고    scopus 로고
    • Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
    • Ohm JE, Mali P, Van Neste L, Berman DM, Liang L, et al. (2010) Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells. Cancer Research 70: 7662-7673.
    • (2010) Cancer Research , vol.70 , pp. 7662-7673
    • Ohm, J.E.1    Mali, P.2    Van Neste, L.3    Berman, D.M.4    Liang, L.5
  • 13
    • 79952536226 scopus 로고    scopus 로고
    • Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures
    • Chou B-K, Mali P, Huang X, Ye Z, Dowey S, et al. (2011) Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res 21: 518-529.
    • (2011) Cell Res , vol.21 , pp. 518-529
    • Chou, B.-K.1    Mali, P.2    Huang, X.3    Ye, Z.4    Dowey, S.5
  • 14
    • 0035923689 scopus 로고    scopus 로고
    • The pattern of gene expression in human CD34(+) stem/progenitor cells
    • Zhou G, Chen J, Lee S, Clark T, Rowley JD, et al. (2001) The pattern of gene expression in human CD34(+) stem/progenitor cells. Proc Natl Acad Sci U S A 98: 13966-13971.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13966-13971
    • Zhou, G.1    Chen, J.2    Lee, S.3    Clark, T.4    Rowley, J.D.5
  • 15
    • 79953126542 scopus 로고    scopus 로고
    • Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias
    • Karp JE, Smith BD, Resar LS, Greer JM, Blackford A, et al. (2011) Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias. Blood 117: 3302-3310.
    • (2011) Blood , vol.117 , pp. 3302-3310
    • Karp, J.E.1    Smith, B.D.2    Resar, L.S.3    Greer, J.M.4    Blackford, A.5
  • 16
    • 80053211500 scopus 로고    scopus 로고
    • Flavopiridol induces BCL-2 expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia
    • Nelson DM, Joseph B, Hillion J, Segal J, Karp JE, et al. (2011) Flavopiridol induces BCL-2 expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia. Leuk Lymphoma 52: 1999-2006.
    • (2011) Leuk Lymphoma , vol.52 , pp. 1999-2006
    • Nelson, D.M.1    Joseph, B.2    Hillion, J.3    Segal, J.4    Karp, J.E.5
  • 17
    • 0033604582 scopus 로고    scopus 로고
    • Function of the c-Myc oncogenic transcription factor
    • Dang CV, Resar LM, Emison E, Kim S, Li Q, et al. (1999) Function of the c-Myc oncogenic transcription factor. Exp Cell Res 253: 63-77.
    • (1999) Exp Cell Res , vol.253 , pp. 63-77
    • Dang, C.V.1    Resar, L.M.2    Emison, E.3    Kim, S.4    Li, Q.5
  • 18
    • 0033881018 scopus 로고    scopus 로고
    • The oncogenic properties of the HMG-I gene family
    • Wood LJ, Maher JF, Bunton TE, Resar LM, (2000) The oncogenic properties of the HMG-I gene family. Cancer Res 60: 4256-4261.
    • (2000) Cancer Res , vol.60 , pp. 4256-4261
    • Wood, L.J.1    Maher, J.F.2    Bunton, T.E.3    Resar, L.M.4
  • 20
    • 0035854047 scopus 로고    scopus 로고
    • Sequence and analysis of the murine Hmgiy (Hmga1) gene locus
    • Pedulla ML, Treff NR, Resar LM, Reeves R, (2001) Sequence and analysis of the murine Hmgiy (Hmga1) gene locus. Gene 271: 51-58.
    • (2001) Gene , vol.271 , pp. 51-58
    • Pedulla, M.L.1    Treff, N.R.2    Resar, L.M.3    Reeves, R.4
  • 22
    • 3042620069 scopus 로고    scopus 로고
    • Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation
    • Dhar A, Hu J, Reeves R, Resar LM, Colburn NH, (2004) Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation. Oncogene 23: 4466-4476.
    • (2004) Oncogene , vol.23 , pp. 4466-4476
    • Dhar, A.1    Hu, J.2    Reeves, R.3    Resar, L.M.4    Colburn, N.H.5
  • 23
    • 2942625408 scopus 로고    scopus 로고
    • High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells
    • Takaha N, Resar LMS, Vindivich D, Coffey DS, (2004) High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells. The Prostate 60: 160-167.
    • (2004) The Prostate , vol.60 , pp. 160-167
    • Takaha, N.1    Resar, L.M.S.2    Vindivich, D.3    Coffey, D.S.4
  • 24
    • 3543089314 scopus 로고    scopus 로고
    • HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells
    • Hommura F, Katabami M, Leaner VD, Donninger H, Sumter TF, et al. (2004) HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells. Mol Cancer Res 2: 305-314.
    • (2004) Mol Cancer Res , vol.2 , pp. 305-314
    • Hommura, F.1    Katabami, M.2    Leaner, V.D.3    Donninger, H.4    Sumter, T.F.5
  • 25
    • 2442668067 scopus 로고    scopus 로고
    • The HMG-I oncogene causes highly penetrant, aggressive lymphoid malignancy in transgenic mice and is overexpressed in human leukemia
    • Xu Y, Sumter TF, Bhattacharya R, Tesfaye A, Fuchs EJ, et al. (2004) The HMG-I oncogene causes highly penetrant, aggressive lymphoid malignancy in transgenic mice and is overexpressed in human leukemia. Cancer Res 64: 3371-3375.
    • (2004) Cancer Res , vol.64 , pp. 3371-3375
    • Xu, Y.1    Sumter, T.F.2    Bhattacharya, R.3    Tesfaye, A.4    Fuchs, E.J.5
  • 26
    • 34249279180 scopus 로고    scopus 로고
    • The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis
    • Tesfaye A, Di Cello F, Hillion J, Ronnett BM, Elbahloul O, et al. (2007) The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis. Cancer Res 67: 3998-4004.
    • (2007) Cancer Res , vol.67 , pp. 3998-4004
    • Tesfaye, A.1    Di Cello, F.2    Hillion, J.3    Ronnett, B.M.4    Elbahloul, O.5
  • 27
    • 36448992338 scopus 로고    scopus 로고
    • Roles of HMGA proteins in cancer
    • Fusco A, Fedele M, (2007) Roles of HMGA proteins in cancer. Nat Rev Cancer 7: 899-910.
    • (2007) Nat Rev Cancer , vol.7 , pp. 899-910
    • Fusco, A.1    Fedele, M.2
  • 28
    • 51049109679 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts
    • Di Cello F, Hillion J, Kowalski J, Ronnett BM, Aderinto A, et al. (2008) Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts. Molecular Cancer Therapeutics 7: 2090-2095.
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 2090-2095
    • Di Cello, F.1    Hillion, J.2    Kowalski, J.3    Ronnett, B.M.4    Aderinto, A.5
  • 29
    • 57749115895 scopus 로고    scopus 로고
    • The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?
    • Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, et al. (2008) The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Res 68: 10121-10127.
    • (2008) Cancer Res , vol.68 , pp. 10121-10127
    • Hillion, J.1    Dhara, S.2    Sumter, T.F.3    Mukherjee, M.4    Di Cello, F.5
  • 30
    • 72449176495 scopus 로고    scopus 로고
    • Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer
    • Hillion J, Wood LJ, Mukherjee M, Bhattacharya R, Di Cello F, et al. (2009) Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer. Mol Cancer Res 7: 1803-1812.
    • (2009) Mol Cancer Res , vol.7 , pp. 1803-1812
    • Hillion, J.1    Wood, L.J.2    Mukherjee, M.3    Bhattacharya, R.4    Di Cello, F.5
  • 31
    • 73949132030 scopus 로고    scopus 로고
    • HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma
    • Hristov AC, Cope L, Di Cello F, Reyes MD, Singh M, et al. (2010) HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma. Mod Pathol 23: 98-104.
    • (2010) Mod Pathol , vol.23 , pp. 98-104
    • Hristov, A.C.1    Cope, L.2    Di Cello, F.3    Reyes, M.D.4    Singh, M.5
  • 32
    • 76549100402 scopus 로고    scopus 로고
    • The High Mobility Group A1 Gene: Transforming Inflammatory Signals into Cancer?
    • Resar LMS, (2010) The High Mobility Group A1 Gene: Transforming Inflammatory Signals into Cancer? Cancer Research 70: 436-439.
    • (2010) Cancer Research , vol.70 , pp. 436-439
    • Resar, L.M.S.1
  • 33
    • 80355125228 scopus 로고    scopus 로고
    • HMGA1 Drives Stem Cell, Inflammatory Pathway, and Cell Cycle Progression Genes During Lymphoid Tumorigenesis
    • Schuldenfrei A, Belton AK, Kowalski J, Talbot CC, Di Cello F, et al. (2011) HMGA1 Drives Stem Cell, Inflammatory Pathway, and Cell Cycle Progression Genes During Lymphoid Tumorigenesis. BMC Genomics 12: 549.
    • (2011) BMC Genomics , vol.12 , pp. 549
    • Schuldenfrei, A.1    Belton, A.K.2    Kowalski, J.3    Talbot, C.C.4    Di Cello, F.5
  • 34
    • 84856055494 scopus 로고    scopus 로고
    • HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells
    • Belton A, Gabrovsky A, Iacobuzio-Donahue C, Huso DL, Resar LMS, (2012) HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells. PLoS One 7: e30034.
    • (2012) PLoS One , vol.7
    • Belton, A.1    Gabrovsky, A.2    Iacobuzio-Donahue, C.3    Huso, D.L.4    Resar, L.M.S.5
  • 35
    • 84859306174 scopus 로고    scopus 로고
    • High Mobility Group A1 and Cancer: Potential Biomarker and Therapeutic Target
    • Shah SN, Resar LMS, (2012) High Mobility Group A1 and Cancer: Potential Biomarker and Therapeutic Target. Histol Histopathol 27: 567-579.
    • (2012) Histol Histopathol , vol.27 , pp. 567-579
    • Shah, S.N.1    Resar, L.M.S.2
  • 36
    • 84866491602 scopus 로고    scopus 로고
    • The HMGA1a-COX-2 axis: A molecular pathway leading to tumor progression in human pancreatic adenocarcinoma Pancreatology
    • Hillion J, Smail S, Di Cello F, Belton A, Huso T, et al. (2012) The HMGA1a-COX-2 axis: A molecular pathway leading to tumor progression in human pancreatic adenocarcinoma Pancreatology. 12: 372-379.
    • (2012) , vol.12 , pp. 372-379
    • Hillion, J.1    Smail, S.2    Di Cello, F.3    Belton, A.4    Huso, T.5
  • 37
    • 84870762302 scopus 로고    scopus 로고
    • The high mobility group A1 oncogene & NF-κB cooperate in malignant transformation
    • [Abstract #3039]
    • Belton A, Paz-Priel I, Friedman AD, Huso D, Resar L (2012) The high mobility group A1 oncogene & NF-κB cooperate in malignant transformation. AACR 2012 [Abstract #3039].
    • (2012) AACR 2012
    • Belton, A.1    Paz-Priel, I.2    Friedman, A.D.3    Huso, D.4    Resar, L.5
  • 38
    • 0026608274 scopus 로고
    • Chromosomal localization of the murine gene and two related sequences encoding high-mobility-group I and Y proteins
    • Johnson KR, Cook SA, Davisson MT, (1992) Chromosomal localization of the murine gene and two related sequences encoding high-mobility-group I and Y proteins. Genomics 12: 503-509.
    • (1992) Genomics , vol.12 , pp. 503-509
    • Johnson, K.R.1    Cook, S.A.2    Davisson, M.T.3
  • 39
    • 0024227436 scopus 로고
    • Complete murine cDNA sequence, genomic structure, and tissue expression of the high mobility group protein HMG-I(Y)
    • Johnson KR, Lehn DA, Elton TS, Barr PJ, Reeves R, (1988) Complete murine cDNA sequence, genomic structure, and tissue expression of the high mobility group protein HMG-I(Y). J Biol Chem 263: 18338-18342.
    • (1988) J Biol Chem , vol.263 , pp. 18338-18342
    • Johnson, K.R.1    Lehn, D.A.2    Elton, T.S.3    Barr, P.J.4    Reeves, R.5
  • 41
    • 58149148165 scopus 로고    scopus 로고
    • HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma
    • Hristov AC, Cope L, Reyes MD, Singh M, Iacobuzio-Donahue C, et al. (2009) HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma. Mod Pathol 22: 43-49.
    • (2009) Mod Pathol , vol.22 , pp. 43-49
    • Hristov, A.C.1    Cope, L.2    Reyes, M.D.3    Singh, M.4    Iacobuzio-Donahue, C.5
  • 42
    • 79957975768 scopus 로고    scopus 로고
    • "Let"-ing go with clonal expansion?
    • Resar LM, Brodsky RA, (2011) "Let"-ing go with clonal expansion? Blood 117: 5788-5790.
    • (2011) Blood , vol.117 , pp. 5788-5790
    • Resar, L.M.1    Brodsky, R.A.2
  • 43
    • 0035962921 scopus 로고    scopus 로고
    • HMGI/Y proteins: flexible regulators of transcription and chromatin structure
    • Reeves R, Beckerbauer L, (2001) HMGI/Y proteins: flexible regulators of transcription and chromatin structure. Biochim Biophys Acta 1519: 13-29.
    • (2001) Biochim Biophys Acta , vol.1519 , pp. 13-29
    • Reeves, R.1    Beckerbauer, L.2
  • 44
    • 80555126799 scopus 로고    scopus 로고
    • AKNA: Another AT-hook transcription factor hooking up with inflammation?
    • Moliterno A, Resar L (2011) AKNA: Another AT-hook transcription factor hooking up with inflammation? Cell Res 21L 1528-1530.
    • (2011) Cell Res , vol.21 L , pp. 1528-1530
    • Moliterno, A.1    Resar, L.2
  • 45
    • 0035164289 scopus 로고    scopus 로고
    • Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells
    • Reeves R, Edberg DD, Li Y, (2001) Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells. Mol Cell Biol 21: 575-594.
    • (2001) Mol Cell Biol , vol.21 , pp. 575-594
    • Reeves, R.1    Edberg, D.D.2    Li, Y.3
  • 46
    • 19944420447 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas
    • Fedele M, Pentimalli F, Baldassarre G, Battista S, Klein-Szanto AJ, et al. (2005) Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas. Oncogene 24: 3427-3435.
    • (2005) Oncogene , vol.24 , pp. 3427-3435
    • Fedele, M.1    Pentimalli, F.2    Baldassarre, G.3    Battista, S.4    Klein-Szanto, A.J.5
  • 47
    • 12444329821 scopus 로고    scopus 로고
    • High mobility group protein HMGA1 expression in breast cancer reveals a positive correlation with tumour grade
    • Flohr AM, Rogalla P, Bonk U, Puettmann B, Buerger H, et al. (2003) High mobility group protein HMGA1 expression in breast cancer reveals a positive correlation with tumour grade. Histol Histopathol 18: 999-1004.
    • (2003) Histol Histopathol , vol.18 , pp. 999-1004
    • Flohr, A.M.1    Rogalla, P.2    Bonk, U.3    Puettmann, B.4    Buerger, H.5
  • 48
    • 0037165140 scopus 로고    scopus 로고
    • Prediction of central nervous system embryonal tumour outcome based on gene expression
    • Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, et al. (2002) Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415: 436-442.
    • (2002) Nature , vol.415 , pp. 436-442
    • Pomeroy, S.L.1    Tamayo, P.2    Gaasenbeek, M.3    Sturla, L.M.4    Angelo, M.5
  • 49
    • 33744501010 scopus 로고    scopus 로고
    • Increased expression of high mobility group A proteins in lung cancer
    • Sarhadi VK, Wikman H, Salmenkivi K, Kuosma E, Sioris T, et al. (2006) Increased expression of high mobility group A proteins in lung cancer. J Pathol 209: 206-212.
    • (2006) J Pathol , vol.209 , pp. 206-212
    • Sarhadi, V.K.1    Wikman, H.2    Salmenkivi, K.3    Kuosma, E.4    Sioris, T.5
  • 50
    • 55749104551 scopus 로고    scopus 로고
    • Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells
    • Zambidis ET, Park TS, Yu W, Tam A, Levine M, et al. (2008) Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells. Blood 112: 3601-3614.
    • (2008) Blood , vol.112 , pp. 3601-3614
    • Zambidis, E.T.1    Park, T.S.2    Yu, W.3    Tam, A.4    Levine, M.5
  • 52
    • 77956542060 scopus 로고    scopus 로고
    • MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells
    • Letzen BS, Liu C, Thakor NV, Gearhart JD, All AH, et al. (2010) MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells. PLoS One 5: e10480.
    • (2010) PLoS One , vol.5
    • Letzen, B.S.1    Liu, C.2    Thakor, N.V.3    Gearhart, J.D.4    All, A.H.5
  • 53
    • 0142227052 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics
    • Kitamura T, Koshino Y, Shibata F, Oki T, Nakajima H, et al. (2003) Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp Hematol 31: 1007-1014.
    • (2003) Exp Hematol , vol.31 , pp. 1007-1014
    • Kitamura, T.1    Koshino, Y.2    Shibata, F.3    Oki, T.4    Nakajima, H.5
  • 54
    • 77953095271 scopus 로고    scopus 로고
    • An improved method for generating and identifying human induced pluripotent stem cells
    • Mali P, Ye Z, Chou BK, Yen J, Cheng L, (2010) An improved method for generating and identifying human induced pluripotent stem cells. Methods Mol Biol 636: 191-205.
    • (2010) Methods Mol Biol , vol.636 , pp. 191-205
    • Mali, P.1    Ye, Z.2    Chou, B.K.3    Yen, J.4    Cheng, L.5
  • 55
    • 70449344685 scopus 로고    scopus 로고
    • Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells
    • Chan EM, Ratanasirintrawoot S, Park IH, Manos PD, Loh YH, et al. (2009) Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat Biotech 27: 1033-1037.
    • (2009) Nat Biotech , vol.27 , pp. 1033-1037
    • Chan, E.M.1    Ratanasirintrawoot, S.2    Park, I.H.3    Manos, P.D.4    Loh, Y.H.5
  • 56
    • 33846223450 scopus 로고    scopus 로고
    • HMGA1 is a determinant of cellular invsiveness and in vivo metastatic potential in pancreatic adenocarcinoma
    • Liau SS, Jazag A, Whang EE, (2006) HMGA1 is a determinant of cellular invsiveness and in vivo metastatic potential in pancreatic adenocarcinoma. Cancer Res 66: 11613-11622.
    • (2006) Cancer Res , vol.66 , pp. 11613-11622
    • Liau, S.S.1    Jazag, A.2    Whang, E.E.3
  • 57
    • 0028971143 scopus 로고
    • MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data
    • Quandt K, Frech K, Karas H, Wingender E, Werner T, (1995) MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 23: 4878-4884.
    • (1995) Nucleic Acids Res , vol.23 , pp. 4878-4884
    • Quandt, K.1    Frech, K.2    Karas, H.3    Wingender, E.4    Werner, T.5
  • 58
    • 0042704717 scopus 로고    scopus 로고
    • Loss of HMGA1 gene function affects embryonic stem cell lympho-hematopoietic differentiation
    • Battista S, Pentimalli F, Baldassarre G, Fedele M, Fidanza V, et al. (2003) Loss of HMGA1 gene function affects embryonic stem cell lympho-hematopoietic differentiation. FASEB J 17: 1496-1498.
    • (2003) FASEB J , vol.17 , pp. 1496-1498
    • Battista, S.1    Pentimalli, F.2    Baldassarre, G.3    Fedele, M.4    Fidanza, V.5
  • 59
    • 0029094755 scopus 로고
    • Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C
    • Zhou X, Benson KF, Ashar HR, Chada K, (1995) Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C. Nature 376: 771-774.
    • (1995) Nature , vol.376 , pp. 771-774
    • Zhou, X.1    Benson, K.F.2    Ashar, H.R.3    Chada, K.4
  • 61
    • 52949125268 scopus 로고    scopus 로고
    • Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
    • Lin SL, Chang DC, Chang-Lin D, Lin CH, We DT, (2008) Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 14: 2115-2124.
    • (2008) RNA , vol.14 , pp. 2115-2124
    • Lin, S.L.1    Chang, D.C.2    Chang-Lin, D.3    Lin, C.H.4    We, D.T.5
  • 62
    • 70350380887 scopus 로고    scopus 로고
    • Sox2 is dispensible for the reprogramming of melanocytes and melanoma cells into induce pluripotent stem cells
    • Utikal J, Maherali N, Kulahert W, Hochedlinger K, (2009) Sox2 is dispensible for the reprogramming of melanocytes and melanoma cells into induce pluripotent stem cells. J Cell Sci 122: 3502-3510.
    • (2009) J Cell Sci , vol.122 , pp. 3502-3510
    • Utikal, J.1    Maherali, N.2    Kulahert, W.3    Hochedlinger, K.4
  • 63
    • 77951623640 scopus 로고    scopus 로고
    • Long-term culture following ES-like gene-induced reprogramming elicits an aggressive phenotype in mutated cholangiocellular carcinoma cells
    • Nagai Ki, Ishii H, Miyoshi N, Hoshino H, Saito T, et al. (2011) Long-term culture following ES-like gene-induced reprogramming elicits an aggressive phenotype in mutated cholangiocellular carcinoma cells. Biochem Biophys Res Commun 395: 258-263.
    • (2011) Biochem Biophys Res Commun , vol.395 , pp. 258-263
    • Nagai, K.1    Ishii, H.2    Miyoshi, N.3    Hoshino, H.4    Saito, T.5
  • 64
    • 79957807595 scopus 로고    scopus 로고
    • Immunogenicity of induced pluripotent stem cells
    • Zhao T, Zhang ZN, Rong Z, Xu Y, (2011) Immunogenicity of induced pluripotent stem cells. Nature 474: 212-215.
    • (2011) Nature , vol.474 , pp. 212-215
    • Zhao, T.1    Zhang, Z.N.2    Rong, Z.3    Xu, Y.4
  • 65
    • 79953015943 scopus 로고    scopus 로고
    • Genome-wide studies reveal that Lin28 enhances the tanslation of genes important for growth and survival of human embryonic stem cells
    • Peng S, Chen LL, Lei XX, Yang L, Lin H, et al. (2011) Genome-wide studies reveal that Lin28 enhances the tanslation of genes important for growth and survival of human embryonic stem cells. Stem Cells 29: 496-504.
    • (2011) Stem Cells , vol.29 , pp. 496-504
    • Peng, S.1    Chen, L.L.2    Lei, X.X.3    Yang, L.4    Lin, H.5
  • 66
    • 0021321996 scopus 로고
    • Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro
    • Andrews PW, Damjanov I, Simon D, Banting GS, Carlin C, et al. (1984) Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro. Lab Invest 50: 147-162.
    • (1984) Lab Invest , vol.50 , pp. 147-162
    • Andrews, P.W.1    Damjanov, I.2    Simon, D.3    Banting, G.S.4    Carlin, C.5
  • 67
    • 0034653531 scopus 로고    scopus 로고
    • The role of high-mobility group I(Y) proteins in expression of IL-2 and T cell proliferation
    • Himes SR, Reeves R, Attema J, Nissen M, Li Y, et al. (2000) The role of high-mobility group I(Y) proteins in expression of IL-2 and T cell proliferation. J Immunol 164: 3157-3168.
    • (2000) J Immunol , vol.164 , pp. 3157-3168
    • Himes, S.R.1    Reeves, R.2    Attema, J.3    Nissen, M.4    Li, Y.5
  • 68
    • 77950630968 scopus 로고    scopus 로고
    • Comparative proteomics of human embryonic stem cells and embryonal carcinoma cells
    • Chaerkady R, Kerr CL, Kandasamy K, Marimuthu A, Gearhart JD, et al. (2010) Comparative proteomics of human embryonic stem cells and embryonal carcinoma cells. Proteomics 10: 1359-1373.
    • (2010) Proteomics , vol.10 , pp. 1359-1373
    • Chaerkady, R.1    Kerr, C.L.2    Kandasamy, K.3    Marimuthu, A.4    Gearhart, J.D.5
  • 69
    • 0035930544 scopus 로고    scopus 로고
    • Characterization of nucleophosmin (B23) as a Myc target by scanning chromatin immunoprecipitation
    • Zeller KI, Haggerty TJ, Barrett JF, Guo Q, Wonsey DR, et al. (2001) Characterization of nucleophosmin (B23) as a Myc target by scanning chromatin immunoprecipitation. J Biol Chem 276: 48285-48291.
    • (2001) J Biol Chem , vol.276 , pp. 48285-48291
    • Zeller, K.I.1    Haggerty, T.J.2    Barrett, J.F.3    Guo, Q.4    Wonsey, D.R.5


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