Tomatidine inhibits invasion of human lung adenocarcinoma cell A549 by reducing matrix metalloproteinases expression

Chemico-Biological Interactions

Volumn 203, Issue 3, 2013, Pages 580-587

  Yan, Kun Huang ^a   Lee, Liang Ming ^a,b   Yan, Shao Han ^c   Huang, Hsiang Ching ^a   Li, Chia Chen ^c   Lin, Hui Ting ^c   Chen, Pin Shern ^c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Invasion; Matrix metalloproteinase; Tomatidine

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PROTEIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REVERSION INDUCING CYSTEINE RICH PROTEIN WITH KAZAL MOTIF; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TOMATIDINE; UNCLASSIFIED DRUG;

ARTICLE; CELL INVASION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; METASTASIS INHIBITION; MIGRATION INHIBITION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; NEOPLASM INVASIVENESS; TOMATINE;

LYCOPERSICON ESCULENTUM;

EID: 84877046974     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.03.016     Document Type: Article

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