Expression of a novel matrix metalloproteinase regulator, RECK, and its clinical significance in resected non-small cell lung cancer

European Journal of Cancer

Volumn 40, Issue 10, 2004, Pages 1617-1623

  Takenaka, Kazumasa ^a   Ishikawa, Shinya ^a   Kawano, Yozo ^a   Yanagihara, Kazuhiro ^a   Miyahara, Ryo ^a   Otake, Yosuke ^b   Morioka, Yoko ^a   Takahashi, Chiaki ^a   Noda, Makoto ^a   Wada, Hiromi ^a   Tanaka, Fumihiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Seishin Iryo Center Hospital   (Japan)

Author keywords

Ad, adenocarcinoma; AI, apoptotic index; EC, endothelial cell; HE, haematoxylin and eosin; IHS, immunohistochemical staining; IMVD, intratumoural microvessel density; La, large cell carcinoma; mAb, monoclonal antibody; MMP, matrix metalloproteinase

Indexed keywords

CD34 ANTIGEN; MATRIX METALLOPROTEINASE; PROTEIN; REVERSION INDUCING CYSTEINE RICH PROTEIN WITH KAZAL MOTIF; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER STAGING; CANCER SURGERY; CANCER TISSUE; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; MALE; MEASUREMENT; MICROVASCULATURE; MULTIVARIATE ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; STAINING; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; TUMOR VASCULARIZATION;

APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL DIVISION; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MULTIVARIATE ANALYSIS; POSTOPERATIVE PERIOD; PROGNOSIS; SURVIVAL ANALYSIS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 2942571345     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2004.02.028     Document Type: Article

References (20)

1. Folkman J., Watson K., Ingiber D., Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature. 339:1989;58-61
2. Folkman J. What is the evidence that tumours are angiogenesis dependent? J. Natl. Cancer Inst. 82:1990;4-6
3. Weidner N. Intratumour microvessel density as a prognostic factor in cancer. Am. J. Pathol. 147:1995;9-19
4. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1:1995;27-31
5. Hlatky L., Hahnfeldt P., Folkman J. Clinical Application of Antiangiogenic Therapy: microvessel density, what it does and doesn't tell us. J. Natl. Cancer Inst. 94:2002;883-893
6. Macchiarini P., Fontanini G., Hardin M.J., Squartini F., Angeletti C.A. Relation of neovascularisation to metastasis of non-small cell lung cancer. Lancet. 340:1992;145-146
7. Yuan A., Yang P.C., Yu C.J., et al. Tumour angiogenesis correlates with histologic type and metastasis in non-small cell lung cancer. Am. J. Respir. Crit. Care Med. 152:1995;2157-2162
8. Tanaka F., Otake Y., Yanagihara K., et al. Evaluation of angiogenesis in non-small cell lung cancer: comparison between anti-CD34 antibody and anti-CD105 antibody. Clin. Cancer Res. 7:2001;3410-3415
9. Chen H.X., Gore-Langton R.E., Cheson B.D. Clinical trials referral resource: current clinical trials of the anti-VEGF monoclonal antibody bevacizumab. Oncology (Huntingt). 8:2001;1023-1026
10. Takahashi C., Sheng Z., Horan T.P., et al. Regulation of matrix metaloprotease-9 and inhibition of tumour invasion by the membrane-anchored glycoprotein RECK. Proc. Natl. Acad. Sci. USA. 95:1998;13221-13226
11. Sasahara R.M., Takahashi C., Noda M. Involvement of the Sp1 site in ras-mediated downregulation of the RECK metastasis suppressor gene. Biochem. Biophys. Res. Comun. 264:1999;668-675
12. Oh J., Takahashi R., Kondo S., et al. The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell. 107:2001;789-800
13. Rhee J.S., Coussens L.M. RECK in MMP function: implications for cancer development. Trends Cell Biol. 12:2002;209-211
14. Furumoto K., Arii S., Mori A., et al. RECK gene expression in hepatocellular carcinoma: correlation with invasion-related clinicopathological factors and its clinical significance. Hepatology. 33:2001;189-195
15. Mountain C.F. Revisions in the international system for staging lung cancer. Chest. 111:1997;1710-1717
16. Travis W.D., Colby T.V., Corrin B., Shimosato Y., Brambilla E. Histological typing of lung and pleural tumours. Travis W.D. World Health Organization International Histological Classification of tumours. Histological typing of lung and pleural tumours. 3rd ed. 1999;21-66 Springer, Berlin
17. Tanaka F., Kawano Y., Li M., et al. Prognostic significance of apoptotic index in completely resected non-small cell lung cancer. J. Clin. Oncol. 17:1999;2728-2736
18. Niedergethmann M., Hildenbrand R., Wostbrock B., et al. High expression of vascular endothelial growth factor predicts early recurrence and poor prognosis after curative resection for ductal adenocarcinoma of the pancreas. Pancreas. 25:2002;122-129
19. Takahashi Y., Bucana C.D., Cleary K.R., Ellis L.M. p53, vessel count, and vascular endothelial growth factor expression in human colon cancer. Int. J. Cancer. 79:1998;34-38
20. Masuya D., Huang C., Liu D., et al. The intratumoural expression of vascular endothelial growth factor and interleukin-8 associated with angiogenesis in non-small cell lung carcinoma patients. Cancer. 92:2001;2628-2638