Synthesis of carbocyclic pyrimidine nucleosides and their inhibitory activities against Plasmodium falciparum thymidylate kinase

Parasitology International

Volumn 62, Issue 4, 2013, Pages 368-371

  Noguchi, Yoshihiro ^a   Yasuda, Yuri ^a   Tashiro, Makoto ^a   Kataoka, Tadashi ^a,b   Kitamura, Yoshiaki ^a   Kandeel, Mahmoud ^a,c   Kitade, Yukio ^a  

^a GIFU UNIVERSITY   (Japan)

^b YOKOHAMA COLLEGE OF PHARMACY   (Japan)

^c Kafrelsheikh University   (Egypt)

Author keywords

Enzyme inhibition; Malaria; Nucleoside derivatives; Thymidylate kinase

Indexed keywords

2' DEOXYPYRIMIDINE NUCLEOSIDE DERIVATIVE; 2',3' DEDEOXYCARBOCYCLIC PYRIMIDINE NUCLEOSIDE DERIVATIVE; ANTIMALARIAL AGENT; CARBOCYCLIC NUCLEOSIDE; DEOXYGUANOSINE PHOSPHATE; PLASMODIUM FALCIPARUM THYMIDYLATE KINASE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME MODIFICATION; ENZYME SUBSTRATE; FLUORINATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANTIMALARIALS; DIDEOXYNUCLEOSIDES; DRUG DISCOVERY; ENZYME INHIBITORS; FLUORINE; MALARIA, FALCIPARUM; NUCLEOSIDE-PHOSPHATE KINASE; PLASMODIUM FALCIPARUM; PYRIMIDINE NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE;

PLASMODIUM FALCIPARUM;

EID: 84877046247     PISSN: 13835769     EISSN: 18730329     Source Type: Journal    
DOI: 10.1016/j.parint.2013.03.009     Document Type: Article

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