Facile synthesis of 9-[(1′R,2′S)-2′-hydroxy-3′-oxocyclopentan-1′ -yl]-9-H-adenine possessing inhibitory activity against human recombinant S-adenosyl-L-homocysteine hydrolase

Tetrahedron Letters

Volumn 42, Issue 3, 2001, Pages 433-435

  Kitade, Yukio ^a   Kozaki, Atushi ^a   Yatome, Chizuko ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Antivirals; Enzyme inhibitors; Hydrolysis; Nucleosides

Indexed keywords

9 (2' HYDROXY 3' OXOCYCLOPENTAN 1' YL) 9H ADENINE; 9 (2',3' O ISOPROPYLIDENEDIOXY 4' CYCLOPENTEN 1' YL) 9H ADENINE; ADENOSYLHOMOCYSTEINASE; ANTIVIRUS AGENT; ENZYME INHIBITOR; HOMOCYSTEINE; HYDROLASE; LITHIUM AZIDE; POTASSIUM TERT BUTOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; INHIBITION KINETICS;

EID: 0035862684     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)01978-X     Document Type: Article

References (15)