Potential application of thymidylate kinase in nucleoside analogue activation in Plasmodium falciparum

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 20, 2010, Pages 7302-7309

  Cui, Huaqing ^a,b   Ruiz Pérez, Luis M ^b   González Pacanowska, Dolores ^b   Gilbert, Ian H ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

Author keywords

Malaria; Plasmodium; Thymidylate kinase

Indexed keywords

3' AZIDO 2',3' DEOXYGUANOSINE; 3' AZIDO 3' DEOXY ALPHA THYMIDINE; 3' AZIDO 5' PHENYL ETHYLOXYVALINYL PHOSPHATE 2',3' DIDEOXYGUANIDINE; 3' AZIDO 5' PHENYL ETHYLOXYVALINYL PHOSPHATE 3' DEOXY ALPHA THYMIDINE; 3' AZIDO 5' PHENYL ETHYLOXYVALINYL PHOSPHATE 3' DEOXYTHYMIDINE; 3' AZIDO 5' PHENYL METHOXYALANINYL PHOSPHATE 3' DEOXY THYMIDINE; 5' PHENYL ETHYLOXYVALINYL PHOSPHATE 2',3' DIDEHYDRO 3' DEOXYTHYMIDINE; 5' PHENYL METHOXYALANINYL PHOSPHATE 2',3' DIDEHYDRO 3' DEOXYTHYMIDINE; ALPHA DEOXYTHYMIDINE; ALPHA ZIDOVUDINE; ANTIPARASITIC AGENT; NUCLEOSIDE; NUCLEOSIDE ANALOG; NUCLEOSIDE PHOSPHATE; PHOSPHOTRANSFERASE; PYRIMIDINE NUCLEOSIDE KINASE; STAVUDINE; THYMIDYLATE KINASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; ENZYME INHIBITORS; HUMANS; NUCLEOSIDE-PHOSPHATE KINASE; NUCLEOSIDES; PLASMODIUM FALCIPARUM; PRODRUGS; ZIDOVUDINE;

PLASMODIUM FALCIPARUM;

EID: 77957559686     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.07.006     Document Type: Article

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