The Impact of Buffer on Solid-State Properties and Stability of Freeze-Dried Dosage Forms

Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals

Volumn , Issue , 2010, Pages 507-519

  Shalaev, Evgenyi Y ^a   Gatlin, Larry A ^a  

^a PFIZER INC   (United States)

Author keywords

Buffer component crystallization mechanisms for changes in solid state acidity and compromised solid state stability; Buffer impact, on solid state properties and freeze dried dosage form stability; Citrate buffer, good choice for formulations prepared at acidic or near neutral pH

Indexed keywords

EID: 84876984379     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470595886.ch20     Document Type: Chapter

References (61)

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