Dynamics of pharmaceutical amorphous solids: The study of enthalpy relaxation by isothermal microcalorimetry

Journal of Pharmaceutical Sciences

Volumn 91, Issue 8, 2002, Pages 1853-1862

  Liu, Jinsong ^a   Rigsbee, Daniel R ^a   Stotz, Carol ^b   Pikal, Michael J ^b  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Amorphous solid; Glassy dynamics; Microcalorimetry; Structural relaxation

Indexed keywords

CARBOHYDRATE DERIVATIVE; LACTOSE; RAFFINOSE; STACHYOSE; SUCROSE; TREHALOSE; UNCLASSIFIED DRUG; DRUG; OLIGOSACCHARIDE;

ARTICLE; CONFORMATIONAL TRANSITION; DRUG CONFORMATION; DRUG STABILITY; ENTHALPY; ISOTHERM; MICROCALORIMETRY; MOLECULAR DYNAMICS; ALGORITHM; CALORIMETRY; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; FREEZE DRYING; HUMIDITY; KINETICS; PHYSICAL CHEMISTRY; REPRODUCIBILITY; TEMPERATURE; THERMODYNAMICS;

ALGORITHMS; CALORIMETRY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHYSICAL; DRUG STABILITY; FREEZE DRYING; HUMIDITY; KINETICS; OLIGOSACCHARIDES; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SUCROSE; TEMPERATURE; THERMODYNAMICS;

EID: 0035991651     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10181     Document Type: Article

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