Identification of NF-κB Inhibitors in Xuebijing injection for sepsis treatment based on bioactivity-integrated UPLC-Q/TOF

Journal of Ethnopharmacology

Volumn 147, Issue 2, 2013, Pages 426-433

  Jiang, Min ^a   Zhou, Mengge ^a   Han, Yanqi ^a   Xing, Lu ^a   Zhao, Hongzhi ^a   Dong, Linyin ^c   Bai, Gang ^a   Luo, Guoan ^a,b  

^a NANKAI UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Bioactivity integrated; NF B inhibitor; Sepsis Anti inflammation; UPLC Q TOF; XBJ injection

Indexed keywords

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; ANTIINFLAMMATORY AGENT; BENZOYLPAEONIFLORIN; CHINESE DRUG; GALLIC ACID; HYDROXYSAFFLOR YELLOW A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; OXYPAEONIFLORIN; PAEONIFLORIN; PROTOCATECHUALDEHYDE; SAFFLOR YELLOW A; SENKYUNOLIDE I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XUEBIJING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MORTALITY; NONHUMAN; PROTEIN EXPRESSION; RAT; SEPSIS; TEMPERATURE; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CHROMATOGRAPHY, LIQUID; CYTOKINES; DRUGS, CHINESE HERBAL; HUMANS; MALE; MASS SPECTROMETRY; NF-KAPPA B; PHYTOTHERAPY; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS;

EID: 84876945369     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.03.032     Document Type: Article

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