Danshensu ameliorates the cognitive decline in streptozotocin-induced diabetic mice by attenuating advanced glycation end product-mediated neuroinflammation

Journal of Neuroimmunology

Volumn 245, Issue 1-2, 2012, Pages 79-86

  Wang, Tian ^a,b   Fu, Fenghua ^b   Han, Bing ^b   Zhang, Leiming ^b   Zhang, Xiumei ^a  

^a SHANDONG UNIVERSITY   (China)

^b YANTAI UNIVERSITY   (China)

Author keywords

Advanced glycation end products; Danshensu; Diabetes; Neuroinflammation

Indexed keywords

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; CYCLOOXYGENASE 2; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 6; PROSTAGLANDIN E2; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; LATENT PERIOD; LEARNING DISORDER; MALE; MAZE TEST; MEMORY DISORDER; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

ANIMALS; COGNITION DISORDERS; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DRUGS, CHINESE HERBAL; GLYCOSYLATION END PRODUCTS, ADVANCED; INFLAMMATION MEDIATORS; LACTATES; MALE; MICE; MICE, INBRED C57BL;

EID: 84862804149     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2012.02.008     Document Type: Article

References (39)

1. Akassoglou K., Probert L., Kontogeorgos G., Kollias G. Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice. J. Immunol. 1997, 158:438-445.
2. Amor S., Puentes F., Baker D., van der Valk P. Inflammation in neurodegenerative diseases. Immunology 2010, 129:154-169.
3. Awad N., Gagnon M., Messier C. The relationship between impaired glucose tolerance, type 2 diabetes, and cognitive function. J. Clin. Exp. Neuropsychol. 2004, 26:1044-1080.
4. Baydas G., Nedzvetskii V.S., Nerush P.A., Kirichenko S.V., Yoldas T. Altered expression of NCAM in hippocampus and cortex may underlie memory and learning deficits in rats with streptozotocin-induced diabetes mellitus. Life Sci. 2003, 73:1907-1916.
5. Bianchi R., Adami C., Giambanco I., Donato R. S100B binding to RAGE in microglia stimulates COX-2 expression. J. Leukoc. Biol. 2007, 81:108-118.
6. Biessels G.J., Kerssen A., de Haan E.H., Kappelle L.J. Cognitive dysfunction and diabetes: implications for primary care. Prim. Care Diabetes 2007, 1:187-193.
7. Brownlee M. Advanced protein glycosylation in diabetes and aging. Annu. Rev. Med. 1995, 46:223-234.
8. Cimino P.J., Keene C.D., Breyer R.M., Montine K.S., Montine T.J. Therapeutic targets in prostaglandin E2 signaling for neurologic disease. Curr. Med. Chem. 2008, 15:1863-1869.
9. Domínguez C., Ruiz E., Gussinye M., Carrascosa A. Oxidative stress at onset and in early stages of type 1 diabetes in children and adolescents. Diabetes Care 1998, 21:1736-1742.
10. Dong K., Xu W., Yang J., Qiao H., Wu L. Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice. Phytother. Res. 2009, 23:608-613.
11. Finch C.E., Cohen D.M. Aging, metabolism, and Alzheimer disease: review and hypotheses. Exp. Neurol. 1997, 143:82-102.
12. Heyser C.J., Masliah E., Samimi A., Campbell I.L., Gold L.H. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:1500-1505.
13. Hofmann M.A., Drury S., Fu C., Qu W., Taguchi A., Lu Y., Avila C., Kambham N., Bierhaus A., Nawroth P., Neurath M.F., Slattery T., Beach D., McClary J., Nagashima M., Morser J., Stern D., Schmidt A.M. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 1999, 97:889-901.
14. Hori O., Brett J., Slattery T., Cao R., Zhang J., Chen J.X., Nagashima M., Lundh E.R., Vijay S., Nitecki D., et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J. Biol. Chem. 1995, 270:25752-25761.
15. Imanshahidi M., Hosseinzadeh H. The pharmacological effects of Salvia species on the central nervous system. Phytother. Res. 2006, 20:427-437.
16. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193:265-275.
17. Lupien S.B., Bluhm E.J., Ishii D.N. Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats. J. Neurosci. Res. 2003, 74:512-523.
18. McKee A.C., Kowall N.W., Schumacher J.S., Beal M.F. The neurotoxicity of amyloid beta protein in aged primates. Amyloid 1998, 5:1-9.
19. Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods 1984, 11:47-60.
20. Mullarkey C.J., Edelstein D., Brownlee M. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem. Biophys. Res. Commun. 1990, 173:932-939.
21. Neumann A., Schinzel R., Palm D., Riederer P., Munch G. High molecular weight hyaluronic acid inhibits advanced glycation endproduct-induced NF-kappaB activation and cytokine expression. FEBS Lett. 1999, 453:283-287.
22. Rösen P., Nawroth P.P., King G., Möller W., Tritschler H.J., Packer L. The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society. Diabetes Metab. Res. Rev. 2001, 17:189-212.
23. Ryan C.M., Freed M.I., Rood J.A., Cobitz A.R., Waterhouse B.R., Strachan M.W. Improving metabolic control leads to better working memory in adults with type 2 diabetes. Diabetes Care 2006, 29:345-351.
24. Shanmugam N., Kim Y.S., Lanting L., Natarajan R. Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products. J. Biol. Chem. 2003, 278:34834-34844.
25. Singh R., Barden A., Mori T., Beilin L. Advanced glycation end-products: a review. Diabetologia 2001, 44:129-146.
26. Tang Y., Wang M., Le X., Meng J., Huang L., Yu P., Chen J., Wu P. Antioxidant and cardioprotective effects of Danshensu (3-(3, 4-dihydroxyphenyl)-2-hydroxy-propanoic acid from Salvia miltiorrhiza) on isoproterenol-induced myocardial hypertrophy in rats. Phytomedicine 2011, 18:1024-1030.
27. Tuzcu M., Baydas G. Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats. Eur. J. Pharmacol. 2006, 537:106-110.
28. Vallieres L., Rivest S. Regulation of the genes encoding interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1beta. J. Neurochem. 1997, 69:1668-1683.
29. van den Berg E., Kloppenborg R.P., Kessels R.P., Kappelle L.J., Biessels G.J. Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: a systematic comparison of their impact on cognition. Biochim. Biophys. Acta 2009, 1792:470-481.
30. Vitek M.P., Bhattacharya K., Glendening J.M., Stopa E., Vlassara H., Bucala R., Manogue K., Cerami A. Advanced glycation end products contribute to amyloidosis in Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:4766-4770.
31. Wautier M.P., Chappey O., Corda S., Stern D.M., Schmidt A.M., Wautier J.L. Activation of NADPH oxidase by advanced glycation end products (AGEs) links oxidant stress to altered gene expression via RAGE. Am. J. Physiol. Endocrinol. Metab. 2001, 280:685-694.
32. Witte M.E., Geurts J.J., de Vries H.E., van der Valk P., van Horssen J. Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?. Mitochondrion 2010, 10(5):411-418.
33. Wong A., Luth H.J., Deuther-Conrad W., Dukic-Stefanovic S., Gasic-Milenkovic J., Arendt T., Munch G. Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease. Brain Res. 2001, 920:32-40.
34. Wrighten S.A., Piroli G.G., Grillo C.A., Reagan L.P. A look inside the diabetic brain: contributors to diabetes-induced brain aging. Biochim. Biophys. Acta 2009, 1792:444-453.
35. Xu G., Zhao W., Zhou Z., Zhang R., Zhu W., Liu X. Danshen extracts decrease blood C reactive protein and prevent ischemic stroke recurrence: a controlled pilot study. Phytother. Res. 2009, 23:1721-1725.
36. Yan S.D., Schmidt A.M., Anderson G.M., Zhang J., Brett J., Zou Y.S., Pinsky D., Stern D. Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins. J. Biol. Chem. 1994, 269:9889-9897.
37. Yeh C.H., Sturgis L., Haidacher J., Zhang X.N., Sherwood S.J., Bjercke R.J., Juhasz O., Crow M.T., Tilton R.G., Denner L. Requirement for p38 and p44/p42 mitogen-activated protein kinases in RAGE-mediated nuclear factor-kappaB transcriptional activation and cytokine secretion. Diabetes 2001, 50:1495-1504.
38. Zhang Q., Yang G., Li W., Fan Z., Sun A., Luo J., Ke Z.J. Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides. Neurobiol. Aging 2011, 32:42-53.
39. Zhao G.R., Zhang H.M., Ye T.X., Xiang Z.J., Yuan Y.J., Guo Z.X., Zhao L.B. Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B. Food Chem. Toxicol. 2008, 46:73-81.