Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias

Journal of Cell Science

Volumn 124, Issue 13, 2011, Pages 2200-2207

  Browne, Gareth ^a   Cipollone, Rita ^b   Lena, Anna Maria ^b   Serra, Valeria ^b   Zhou, Huiqing ^c   van Bokhoven, Hans ^c   Dötsch, Volker ^d   Merico, Daniele ^e   Mantovani, Roberto ^e   Terrinoni, Alessandro ^b   Knight, Richard A ^a   Candi, Eleonora ^b   Melino, Gerry ^a,b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d GOETHE UNIVERSITY   (Germany)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

Ectodermal dysplasia protein; Itch; P63; Skin; Stability

Indexed keywords

ISOPROTEIN; MUTANT PROTEIN; PROTEIN P63; UBIQUITIN PROTEIN LIGASE E3;

AEC SYNDROME; ARTICLE; CONTROLLED STUDY; ECTRODACTYLY; EEC SYNDROME; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY;

CLEFT LIP; CLEFT PALATE; DNA-BINDING PROTEINS; ECTODERMAL DYSPLASIA; EYE ABNORMALITIES; EYELIDS; GENETIC DISEASES, X-LINKED; HALF-LIFE; HEK293 CELLS; HUMANS; LIMB DEFORMITIES, CONGENITAL; MEMBRANE PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; PROTEIN STABILITY; RECEPTORS, LDL; REPRESSOR PROTEINS; TRANSCRIPTIONAL ACTIVATION; UBIQUITIN-PROTEIN LIGASES;

EID: 79960336511     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.079327     Document Type: Article

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