-
2
-
-
70349705441
-
Prions: protein aggregation and infectious diseases
-
Aguzzi A, Calella AM, (2009) Prions: protein aggregation and infectious diseases. Physiol Rev 89: 1105-1152.
-
(2009)
Physiol Rev
, vol.89
, pp. 1105-1152
-
-
Aguzzi, A.1
Calella, A.M.2
-
3
-
-
84864140925
-
Spread of Classic BSE Prions from the Gut via the Peripheral Nervous System to the Brain
-
Kaatz M, Fast C, Ziegler U, Balkema-Buschmann A, Hammerschmidt B, et al. (2012) Spread of Classic BSE Prions from the Gut via the Peripheral Nervous System to the Brain. Am J Pathol 181: 515-524.
-
(2012)
Am J Pathol
, vol.181
, pp. 515-524
-
-
Kaatz, M.1
Fast, C.2
Ziegler, U.3
Balkema-Buschmann, A.4
Hammerschmidt, B.5
-
4
-
-
0242361687
-
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease
-
Glatzel M, Abela E, Maissen M, Aguzzi A, (2003) Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease. N Engl J Med 349: 1812-1820.
-
(2003)
N Engl J Med
, vol.349
, pp. 1812-1820
-
-
Glatzel, M.1
Abela, E.2
Maissen, M.3
Aguzzi, A.4
-
5
-
-
0031444295
-
A crucial role for B cells in neuroinvasive scrapie
-
Klein MA, Frigg R, Flechsig E, Raeber AJ, Kalinke U, et al. (1997) A crucial role for B cells in neuroinvasive scrapie. Nature 390: 687-690.
-
(1997)
Nature
, vol.390
, pp. 687-690
-
-
Klein, M.A.1
Frigg, R.2
Flechsig, E.3
Raeber, A.J.4
Kalinke, U.5
-
6
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner SB, (1982) Novel proteinaceous infectious particles cause scrapie. Science 216: 136-144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
7
-
-
0015550206
-
Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation
-
Fraser H, Dickinson AG, (1973) Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation. J Comp Pathol 83: 29-40.
-
(1973)
J Comp Pathol
, vol.83
, pp. 29-40
-
-
Fraser, H.1
Dickinson, A.G.2
-
8
-
-
0141515178
-
TSE strain variation
-
Bruce ME, (2003) TSE strain variation. Br Med Bull 66: 99-108.
-
(2003)
Br Med Bull
, vol.66
, pp. 99-108
-
-
Bruce, M.E.1
-
9
-
-
36049020231
-
A general model of prion strains and their pathogenicity
-
Collinge J, Clarke AR, (2007) A general model of prion strains and their pathogenicity. Science 318: 930-936.
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
10
-
-
77954051480
-
The physical relationship between infectivity and prion protein aggregates is strain-dependent
-
Tixador P, Herzog L, Reine F, Jaumain E, Chapuis J, et al. (2010) The physical relationship between infectivity and prion protein aggregates is strain-dependent. PLoS Pathog 6: e1000859.
-
(2010)
PLoS Pathog
, vol.6
-
-
Tixador, P.1
Herzog, L.2
Reine, F.3
Jaumain, E.4
Chapuis, J.5
-
11
-
-
0035086136
-
Strain-specified relative conformational stability of the scrapie prion protein
-
Peretz D, Scott MR, Groth D, Williamson RA, Burton DR, et al. (2001) Strain-specified relative conformational stability of the scrapie prion protein. Protein Sci 10: 854-863.
-
(2001)
Protein Sci
, vol.10
, pp. 854-863
-
-
Peretz, D.1
Scott, M.R.2
Groth, D.3
Williamson, R.A.4
Burton, D.R.5
-
12
-
-
0029831213
-
Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD
-
Collinge J, Sidle KC, Meads J, Ironside J, Hill AF, (1996) Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature 383: 685-690.
-
(1996)
Nature
, vol.383
, pp. 685-690
-
-
Collinge, J.1
Sidle, K.C.2
Meads, J.3
Ironside, J.4
Hill, A.F.5
-
13
-
-
0028997297
-
Non-genetic propagation of strain-specific properties of scrapie prion protein
-
Bessen RA, Kocisko DA, Raymond GJ, Nandan S, Lansbury PT, et al. (1995) Non-genetic propagation of strain-specific properties of scrapie prion protein. Nature 375: 698-700.
-
(1995)
Nature
, vol.375
, pp. 698-700
-
-
Bessen, R.A.1
Kocisko, D.A.2
Raymond, G.J.3
Nandan, S.4
Lansbury, P.T.5
-
14
-
-
0026583834
-
Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent
-
Bessen RA, Marsh RF, (1992) Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent. J Virol 66: 2096-2101.
-
(1992)
J Virol
, vol.66
, pp. 2096-2101
-
-
Bessen, R.A.1
Marsh, R.F.2
-
15
-
-
0032813254
-
Differences in Proteinase K Resistance and Neuronal Deposition of Abnormal Prion Proteins Characterize Bovine Spongiform Encephalopathy (BSE) and Scrapie Strains
-
Kuczius T, Groschup MH, (1999) Differences in Proteinase K Resistance and Neuronal Deposition of Abnormal Prion Proteins Characterize Bovine Spongiform Encephalopathy (BSE) and Scrapie Strains. Mol Med 5: 406-418.
-
(1999)
Mol Med
, vol.5
, pp. 406-418
-
-
Kuczius, T.1
Groschup, M.H.2
-
16
-
-
79953286302
-
The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease
-
Ayers JI, Schutt CR, Shikiya RA, Aguzzi A, Kincaid AE, et al. (2011) The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease. PLoS Pathog 7: e1001317.
-
(2011)
PLoS Pathog
, vol.7
-
-
Ayers, J.I.1
Schutt, C.R.2
Shikiya, R.A.3
Aguzzi, A.4
Kincaid, A.E.5
-
17
-
-
69949187643
-
Molecular mechanisms for protein-encoded inheritance
-
Wiltzius JJ, Landau M, Nelson R, Sawaya MR, Apostol MI, et al. (2009) Molecular mechanisms for protein-encoded inheritance. Nat Struct Mol Biol 16: 973-978.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 973-978
-
-
Wiltzius, J.J.1
Landau, M.2
Nelson, R.3
Sawaya, M.R.4
Apostol, M.I.5
-
18
-
-
12644272790
-
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
-
Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, et al. (1996) Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science 274: 2079-2082.
-
(1996)
Science
, vol.274
, pp. 2079-2082
-
-
Telling, G.C.1
Parchi, P.2
DeArmond, S.J.3
Cortelli, P.4
Montagna, P.5
-
19
-
-
0023663071
-
Scrapie prion protein contains a phosphatidylinositol glycolipid
-
Stahl N, Borchelt DR, Hsiao K, Prusiner SB, (1987) Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell 51: 229-240.
-
(1987)
Cell
, vol.51
, pp. 229-240
-
-
Stahl, N.1
Borchelt, D.R.2
Hsiao, K.3
Prusiner, S.B.4
-
20
-
-
0027520888
-
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells
-
Rogers M, Yehiely F, Scott M, Prusiner SB, (1993) Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells. Proc Natl Acad Sci U S A 90: 3182-3186.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 3182-3186
-
-
Rogers, M.1
Yehiely, F.2
Scott, M.3
Prusiner, S.B.4
-
21
-
-
84859488323
-
Gerstmann-Straussler-Scheinker disease
-
Liberski PP, (2012) Gerstmann-Straussler-Scheinker disease. Adv Exp Med Biol 724: 128-137.
-
(2012)
Adv Exp Med Biol
, vol.724
, pp. 128-137
-
-
Liberski, P.P.1
-
22
-
-
84855485942
-
Spontaneous generation of anchorless prions in transgenic mice
-
Stohr J, Watts JC, Legname G, Oehler A, Lemus A, et al. (2011) Spontaneous generation of anchorless prions in transgenic mice. Proc Natl Acad Sci U S A 108: 21223-21228.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 21223-21228
-
-
Stohr, J.1
Watts, J.C.2
Legname, G.3
Oehler, A.4
Lemus, A.5
-
23
-
-
20344394154
-
Anchorless prion protein results in infectious amyloid disease without clinical scrapie
-
Chesebro B, Trifilo M, Race R, Meade-White K, Teng C, et al. (2005) Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science 308: 1435-1439.
-
(2005)
Science
, vol.308
, pp. 1435-1439
-
-
Chesebro, B.1
Trifilo, M.2
Race, R.3
Meade-White, K.4
Teng, C.5
-
24
-
-
77950379326
-
Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring
-
Chesebro B, Race B, Meade-White K, Lacasse R, Race R, et al. (2010) Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring. PLoS Pathog 6: e1000800.
-
(2010)
PLoS Pathog
, vol.6
-
-
Chesebro, B.1
Race, B.2
Meade-White, K.3
Lacasse, R.4
Race, R.5
-
25
-
-
78951477465
-
Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection
-
Klingeborn M, Race B, Meade-White KD, Rosenke R, Striebel JF, et al. (2011) Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection. J Virol 85: 1484-1494.
-
(2011)
J Virol
, vol.85
, pp. 1484-1494
-
-
Klingeborn, M.1
Race, B.2
Meade-White, K.D.3
Rosenke, R.4
Striebel, J.F.5
-
26
-
-
84860903170
-
Biochemical properties of highly neuroinvasive prion strains
-
Bett C, Joshi-Barr S, Lucero M, Trejo M, Liberski P, et al. (2012) Biochemical properties of highly neuroinvasive prion strains. PLoS Pathogens 8: e1002522.
-
(2012)
PLoS Pathogens
, vol.8
-
-
Bett, C.1
Joshi-Barr, S.2
Lucero, M.3
Trejo, M.4
Liberski, P.5
-
27
-
-
0022365237
-
Long-term persistence of scrapie infection in mouse spleens in the absence of clinical disease
-
Collis SC, Kimberlin RH, (1985) Long-term persistence of scrapie infection in mouse spleens in the absence of clinical disease. FEMS Microbiology Letters 29: 111-114.
-
(1985)
FEMS Microbiology Letters
, vol.29
, pp. 111-114
-
-
Collis, S.C.1
Kimberlin, R.H.2
-
28
-
-
38949108662
-
Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD
-
Beringue V, Le Dur A, Tixador P, Reine F, Lepourry L, et al. (2008) Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD. PLoS ONE 3: e1419.
-
(2008)
PLoS ONE
, vol.3
-
-
Beringue, V.1
Le Dur, A.2
Tixador, P.3
Reine, F.4
Lepourry, L.5
-
29
-
-
33745910558
-
Prion-induced amyloid heart disease with high blood infectivity in transgenic mice
-
Trifilo MJ, Yajima T, Gu Y, Dalton N, Peterson KL, et al. (2006) Prion-induced amyloid heart disease with high blood infectivity in transgenic mice. Science 313: 94-97.
-
(2006)
Science
, vol.313
, pp. 94-97
-
-
Trifilo, M.J.1
Yajima, T.2
Gu, Y.3
Dalton, N.4
Peterson, K.L.5
-
30
-
-
58149250621
-
Detection of prion infectivity in fat tissues of scrapie-infected mice
-
Race B, Meade-White K, Oldstone MB, Race R, Chesebro B, (2008) Detection of prion infectivity in fat tissues of scrapie-infected mice. PLoS Pathog 4: e1000232.
-
(2008)
PLoS Pathog
, vol.4
-
-
Race, B.1
Meade-White, K.2
Oldstone, M.B.3
Race, R.4
Chesebro, B.5
-
31
-
-
79958177750
-
Effect of glycans and the glycophosphatidylinositol anchor on strain dependent conformations of scrapie prion protein: improved purifications and infrared spectra
-
Baron GS, Hughson AG, Raymond GJ, Offerdahl DK, Barton KA, et al. (2011) Effect of glycans and the glycophosphatidylinositol anchor on strain dependent conformations of scrapie prion protein: improved purifications and infrared spectra. Biochemistry 50: 4479-4490.
-
(2011)
Biochemistry
, vol.50
, pp. 4479-4490
-
-
Baron, G.S.1
Hughson, A.G.2
Raymond, G.J.3
Offerdahl, D.K.4
Barton, K.A.5
-
32
-
-
70349858126
-
Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils
-
Sim VL, Caughey B, (2008) Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils. Neurobiol Aging 30: 2031-42.
-
(2008)
Neurobiol Aging
, vol.30
, pp. 2031-2042
-
-
Sim, V.L.1
Caughey, B.2
-
33
-
-
58149280203
-
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin
-
Cronier S, Gros N, Tattum MH, Jackson GS, Clarke AR, et al. (2008) Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin. Biochem J 416: 297-305.
-
(2008)
Biochem J
, vol.416
, pp. 297-305
-
-
Cronier, S.1
Gros, N.2
Tattum, M.H.3
Jackson, G.S.4
Clarke, A.R.5
-
34
-
-
0037071874
-
A change in the conformation of prions accompanies the emergence of a new prion strain
-
Peretz D, Williamson RA, Legname G, Matsunaga Y, Vergara J, et al. (2002) A change in the conformation of prions accompanies the emergence of a new prion strain. Neuron 34: 921-932.
-
(2002)
Neuron
, vol.34
, pp. 921-932
-
-
Peretz, D.1
Williamson, R.A.2
Legname, G.3
Matsunaga, Y.4
Vergara, J.5
-
35
-
-
77449089995
-
Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP
-
Jansen C, Parchi P, Capellari S, Vermeij AJ, Corrado P, et al. (2010) Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP. Acta Neuropathol 119: 189-197.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 189-197
-
-
Jansen, C.1
Parchi, P.2
Capellari, S.3
Vermeij, A.J.4
Corrado, P.5
-
36
-
-
0038690113
-
Cross-beta order and diversity in nanocrystals of an amyloid-forming peptide
-
Diaz-Avalos R, Long C, Fontano E, Balbirnie M, Grothe R, et al. (2003) Cross-beta order and diversity in nanocrystals of an amyloid-forming peptide. J Mol Biol 330: 1165-1175.
-
(2003)
J Mol Biol
, vol.330
, pp. 1165-1175
-
-
Diaz-Avalos, R.1
Long, C.2
Fontano, E.3
Balbirnie, M.4
Grothe, R.5
-
37
-
-
12244249201
-
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils
-
Petkova AT, Leapman RD, Guo Z, Yau WM, Mattson MP, et al. (2005) Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science 307: 262-265.
-
(2005)
Science
, vol.307
, pp. 262-265
-
-
Petkova, A.T.1
Leapman, R.D.2
Guo, Z.3
Yau, W.M.4
Mattson, M.P.5
-
38
-
-
34249290108
-
Atomic structures of amyloid cross-beta spines reveal varied steric zippers
-
Sawaya MR, Sambashivan S, Nelson R, Ivanova MI, Sievers SA, et al. (2007) Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature 447: 453-457.
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
Sambashivan, S.2
Nelson, R.3
Ivanova, M.I.4
Sievers, S.A.5
-
39
-
-
0032506114
-
Propagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact register
-
Benzinger TL, Gregory DM, Burkoth TS, Miller-Auer H, Lynn DG, et al. (1998) Propagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact register. Proc Natl Acad Sci U S A 95: 13407-13412.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13407-13412
-
-
Benzinger, T.L.1
Gregory, D.M.2
Burkoth, T.S.3
Miller-Auer, H.4
Lynn, D.G.5
-
40
-
-
84863834613
-
Dissecting Structure of Prion Amyloid Fibrils by Hydrogen-Deuterium Exchange Ultraviolet Raman Spectroscopy
-
Shashilov V, Xu M, Makarava N, Savtchenko R, Baskakov IV, et al. (2012) Dissecting Structure of Prion Amyloid Fibrils by Hydrogen-Deuterium Exchange Ultraviolet Raman Spectroscopy. J Phys Chem B 2012 Jun 26. Epub ahead of print.
-
(2012)
J Phys Chem B
-
-
Shashilov, V.1
Xu, M.2
Makarava, N.3
Savtchenko, R.4
Baskakov, I.V.5
-
41
-
-
33746698975
-
The physical basis of how prion conformations determine strain phenotypes
-
Tanaka M, Collins SR, Toyama BH, Weissman JS, (2006) The physical basis of how prion conformations determine strain phenotypes. Nature 442: 585-589.
-
(2006)
Nature
, vol.442
, pp. 585-589
-
-
Tanaka, M.1
Collins, S.R.2
Toyama, B.H.3
Weissman, J.S.4
-
42
-
-
34548615995
-
The structural basis of yeast prion strain variants
-
Toyama BH, Kelly MJ, Gross JD, Weissman JS, (2007) The structural basis of yeast prion strain variants. Nature 449: 233-237.
-
(2007)
Nature
, vol.449
, pp. 233-237
-
-
Toyama, B.H.1
Kelly, M.J.2
Gross, J.D.3
Weissman, J.S.4
-
43
-
-
69949142350
-
Distinct structures of scrapie prion protein (PrPSc)-seeded versus spontaneous recombinant prion protein fibrils revealed by hydrogen/deuterium exchange
-
Smirnovas V, Kim JI, Lu X, Atarashi R, Caughey B, et al. (2009) Distinct structures of scrapie prion protein (PrPSc)-seeded versus spontaneous recombinant prion protein fibrils revealed by hydrogen/deuterium exchange. J Biol Chem 284: 24233-24241.
-
(2009)
J Biol Chem
, vol.284
, pp. 24233-24241
-
-
Smirnovas, V.1
Kim, J.I.2
Lu, X.3
Atarashi, R.4
Caughey, B.5
-
44
-
-
43249086837
-
Host PrP glycosylation: a major factor determining the outcome of prion infection
-
Tuzi NL, Cancellotti E, Baybutt H, Blackford L, Bradford B, et al. (2008) Host PrP glycosylation: a major factor determining the outcome of prion infection. PLoS Biol 6: e100.
-
(2008)
PLoS Biol
, vol.6
-
-
Tuzi, N.L.1
Cancellotti, E.2
Baybutt, H.3
Blackford, L.4
Bradford, B.5
-
45
-
-
80051714126
-
Seeding specificity and ultrastructural characteristics of infectious recombinant prions
-
Piro JR, Wang F, Walsh DJ, Rees JR, Ma J, et al. (2011) Seeding specificity and ultrastructural characteristics of infectious recombinant prions. Biochemistry 50: 7111-7116.
-
(2011)
Biochemistry
, vol.50
, pp. 7111-7116
-
-
Piro, J.R.1
Wang, F.2
Walsh, D.J.3
Rees, J.R.4
Ma, J.5
-
46
-
-
84864064734
-
Propagation of RML Prions in Mice Expressing PrP Devoid of GPI Anchor Leads to Formation of a Novel, Stable Prion Strain
-
Mahal SP, Jablonski J, Suponitsky-Kroyter I, Oelschlegel AM, Herva ME, et al. (2012) Propagation of RML Prions in Mice Expressing PrP Devoid of GPI Anchor Leads to Formation of a Novel, Stable Prion Strain. PLoS Pathog 8: e1002746.
-
(2012)
PLoS Pathog
, vol.8
-
-
Mahal, S.P.1
Jablonski, J.2
Suponitsky-Kroyter, I.3
Oelschlegel, A.M.4
Herva, M.E.5
-
47
-
-
0014308027
-
The sequential development of the brain lesion of scrapie in three strains of mice
-
Fraser H, Dickinson AG, (1968) The sequential development of the brain lesion of scrapie in three strains of mice. J Comp Pathol 78: 301-311.
-
(1968)
J Comp Pathol
, vol.78
, pp. 301-311
-
-
Fraser, H.1
Dickinson, A.G.2
-
48
-
-
0026099887
-
The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis
-
Bruce ME, McConnell I, Fraser H, Dickinson AG, (1991) The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J Gen Virol 72: 595-603.
-
(1991)
J Gen Virol
, vol.72
, pp. 595-603
-
-
Bruce, M.E.1
McConnell, I.2
Fraser, H.3
Dickinson, A.G.4
-
49
-
-
0035928432
-
Tissue distribution of protease resistant prion protein in variant CJD using a highly sensitive immuno-blotting assay
-
Wadsworth JDF, Joiner S, Hill AF, Campbell TA, Desbruslais M, Luthert PJ, Collinge J, (2001) Tissue distribution of protease resistant prion protein in variant CJD using a highly sensitive immuno-blotting assay. Lancet 358: 171-180.
-
(2001)
Lancet
, vol.358
, pp. 171-180
-
-
Wadsworth, J.D.F.1
Joiner, S.2
Hill, A.F.3
Campbell, T.A.4
Desbruslais, M.5
Luthert, P.J.6
Collinge, J.7
-
50
-
-
57549096688
-
The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes
-
Polymenidou M, Moos R, Scott M, Sigurdson C, Shi YZ, et al. (2008) The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes. PLoS ONE 3: e3872.
-
(2008)
PLoS ONE
, vol.3
-
-
Polymenidou, M.1
Moos, R.2
Scott, M.3
Sigurdson, C.4
Shi, Y.Z.5
|