Effects of low dose treatment of tributyltin on the regulation of estrogen receptor functions in MCF-7 cells

Toxicology and Applied Pharmacology

Volumn 269, Issue 2, 2013, Pages 176-186

  Sharan, Shruti ^a   Nikhil, Kumar ^a   Roy, Partha ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

Author keywords

Aromatase; Cell proliferation; Endocrine disruptors; Estrogen receptor; Tributyltin chloride

Indexed keywords

AROMATASE; BETA ACTIN; ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STEROID 5ALPHA REDUCTASE; TRANSCRIPTION FACTOR AP 1; TRIBUTYLTIN CHLORIDE;

ARTICLE; CELL ASSAY; CELL CULTURE; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

3-HYDROXYSTEROID DEHYDROGENASES; CELL PROLIFERATION; ENDOCRINE DISRUPTORS; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION REGULATION; HUMANS; MCF-7 CELLS; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TRIALKYLTIN COMPOUNDS;

EID: 84876732824     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.03.009     Document Type: Article

References (69)

1. Antizar-Ladislao B. Environmental levels, toxicity and human exposure to tributyltin (TBT) contaminated marine environment. A review. Environ. Int. 2008, 34:292-308.
2. Aronica S.M., Katzenellenbogen B.S. Progesterone receptor regulation in uterine cells: stimulation by estrogen, cyclic adenosine 3',5'-monophosphate, and insulin-like growth factor I and suppression by antiestrogens and protein kinase inhibitors. Endocrinology 1991, 128:2045-2052.
3. Bauer B., Fioroni P., Ide I., Liebe S., Oehlmann J., Stroben E., Watermann B. TBT effects on the female genital system of Littorina littorea, a possible indicator of tributyltin pollution. Hydrobiologia 1995, 309:15-27.
4. Blunden S.J., Evans C.J. The Handbook of Environmental Chemistry 1990, Springer-Verlag, Berlin. O. Hutzinger (Ed.).
5. Blunden S.J., Hobbs L.A., Smith P.J. The environmental chemistry of organotin compounds. Environmental Chemistry 1984, The Royal Society of Chemistry, London. H.J.M. Bowen (Ed.).
6. Bonni A., Brunet A., West A.E., Datta S.R., Takasu M.A., Greenberg M.E. Cell survival promoted by the Ras-MAPK signaling pathway by transcription dependent and independent mechanisms. Science 1999, 286:1358-1362.
7. Burak W.E., Quinn A.L., Farrar W.B. Androgens influence estrogen induced responses in human breast carcinoma cells through cytochrome P450 aromatase. Breast Cancer Res. Treat. 1997, 44:57-64.
8. Chomczynski P., Sacchi N. Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987, 162(1):156-159.
9. Cooke G.M. Effect of organotins on human aromatase activity in vitro. Toxicol. Lett. 2002, 126:121-130.
10. Darbre P.D. Environmental oestrogens, cosmetics and breast cancer. Best Pract. Res. Clin. Endocrinol. Metab. 2006, 20:121-143.
11. Dickson R.B., Lippman M.E. Growth factors in breast cancer. Endocr. Rev. 1995, 16:559-589.
12. Doering D.D., Doering S.S.T., Dietrich K. Effects of butyltins on human 5α-reductase type 1 and type 2 activity. Steroids 2002, 67:859-867.
13. Duan R., Xie W., Burgshardt R.C., Safe S. Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1. J. Biol. Chem. 2001, 276:11590-11598.
14. Dubey S.K., Roy U. Biodegradation of tributyltins (organotins) by marine bacteria. Appl. Organomet. Chem. 2003, 17:3-8.
15. Durando M., Kass L., Virginia P., Bosquiazzo V.L., Luque E.H., Toro M.M.D. Prenatal exposure to bisphenol A promotes angiogenesis and alters steroid-mediated responses in the mammary glands of cycling rats. J. Steroid Biochem. Mol. Biol. 2011, 12:35-43.
16. EPA, Environmental Protection Agency Ambient aquatic life water quality criteria for tributyltin (TBT)-final 2003.
17. Faulds M.H., Zhao C., Wright K.D., Gustafsson J. The diversity of sex steroid action: regulation of metabolism by estrogen signaling. J. Endocrinol. 2012, 212:3-12.
18. Féral C., LeGall S. The influence of a pollutant factor (TBT) on the neurosecretory mechanism responsible for the occurrence of a penis in the females of Ocenebra erinacea. Molluscan Neuro-Endocrinology 1983, 173-175. North Holland Publishing, Amsterdam, The Netherlands. J. Lever, H.H. Boer (Eds.).
19. Fenton S.E. Endocrine-disrupting compounds and mammary gland development: early exposure and later life consequences. Endocrinology 2006, 147:S18-S24.
20. Gibbs P.E., Bryan G.W. Reproductive failure in populations of the dog-whelk, Nucella lapillus, caused by imposex induced by tributyltin from antifouling paints. J. Mar. Biol. Assoc. U. K. 1986, 66:767-777.
21. Gibbs P.E., Bryan G.W. TBT-induced imposex in neogastropod snails: masculinization to mass extinction. Tributyltin: Case Study of an Environmental Contaminant 1996, 212-236. Cambridge University Press, Cambridge. S.J. de Mora (Ed.).
22. Go V., Garey J., Wolff M.S., Pogo B.G. Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line. Environ. Health Perspect. 1999, 107:173-177.
23. Han E.H., Kim J.Y., Kim H.K., Hwang Yong P., Jeongo H.G. o,p'-DDT induces cyclooxygenase-2 gene expression in murine macrophages: role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways. Toxicol. Appl. Pharmacol. 2008, 233:333-342.
24. Heidrich D.D., Steckelbroek S., Klingmuller D. Inhibition of human cytochrome P450 aromatase activity by butyltins. Steroids 2001, 66:763-769.
25. Hongxia L., Guolan H., Shugui D. Toxicity and accumulation of tributyltin chloride on tilapia. Appl. Organomet. Chem. 1998, 12:109-119.
26. Horiguchi T., Shiraishi H., Shimizu M., Yamazaki S., Morita M. Imposex in Japanese gastropods (Neogastropoda and Mesogastropoda): effects of tributyltin and triphenyltin from antifouling paints. Mar. Pollut. Bull. 1995, 31:402-405.
27. Horiguchi T., Shiraishi H., Shimizu M., Morita M. Effects of triphenyltin chloride and five other organotin compounds on the development of imposex in the rock shell, Thais clavigera. Environ. Pollut. 1997, 95:85-91.
28. IMO International Convention on the Control of Harmful Antifouling Systems on Ships 2001, International Maritime Organisation, London UK.
29. Inoue S., Abe S., Oshima Y., Kai N., Honjo T. Tributyltin contamination of bivalves in coastal areas around northern Kyushu, Japan. Environ. Toxicol. 2006, 21:244-249.
30. Jager D.T., Pelzer T., Muller-Botz S., Imam A., Muck J., Neyses L. Mechanisms of estrogen receptor action in the myocardium. Rapid gene activation via the ERK1/2 pathway and serum response elements. J. Biol. Chem. 2001, 276:27873-27880.
31. Kinoshita Y., Chen S. Induction of aromatase (CYP19) expression in breast cancer cells through a nongenomic action of estrogen α receptor. Cancer Res. 2003, 63:3546-3555.
32. Kushner P.J., Agard D.A., Greene G.L., Scanlan T.S., Shiau A.K., Uht R.M., Webb P. Estrogen receptor pathways to AP-1. J. Steroid Biochem. Mol. Biol. 2000, 74:311-317.
33. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227(5259):680-685.
34. Lazennec G., Bresson D., Lucas A., Chauveau C., Vignon F. ER β inhibits proliferation and invasion of breast cancer cells. Endocrinology 2001, 142(9):4120-4130.
35. LeBlanc G.A., McLachlan J.B. Changes in the metabolic elimination profile of testosterone following exposure of the crustacean daphnia magna to tributyltin. Ecotoxicol. Environ. Saf. 2000, 45:296-303.
36. Lee R.F. Metabolism of tributyltin oxide by crabs, oysters and fish. Mar. Environ. Res. 1985, 17:145-148.
37. Lee S., Na S., Jung S., Choi J., Jhun B., Cheong J., Paul S.M., Lee Y.C., Lee J.W. Activating protein-1, nuclear factor-kB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2. Mol. Endocrinol. 2000, 14(6):915-925.
38. Losel R., Wehling M. Nongenomic actions of steroid hormones. Nat. Rev. Mol. Cell Biol. 2003, 4:46-56.
39. Lundquist J., Norlin M., Wickvall K. 1α,25-Dihydroxyvitamin D3 exerts tissue-specific effects on estrogen and androgen metabolism. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 2011, 1811:263-270.
40. Matthiessen P., Gibbs P. Critical appraisal of the evidence for tributyltin-mediated endocrine disruption in mollusks. Environ. Toxicol. Chem. 1998, 17:37-43.
41. McKenna N.J., Lanz R.B., O'Malley B.W. Nuclear receptor coregulators: cellular and molecular biology. Endocr. Rev. 1999, 20:321-344.
42. Mossman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65(1-2):55-63.
43. Nakanishi T., Kohroki J., Suzuki S., Ishizaki J., Hiromori Y., Takasuga S., Itoh N., Watanabe Y., Utoguchi N., Tanaka K. Trialkyltin compounds enhance human CG secretion and aromatase activity in human placental choriocarcinoma cells. J. Clin. Endocrinol. Metab. 2002, 87(6):2830-2837.
44. Nakanishi T., Hiromori Y., Yokoyama H., Koyanagi M., Itoh N., Nishikawa J., Tanaka K. Organotin compounds enhance 17β-hydroxysteroid dehydrogenase type I activity in human choriocarcinoma JAr cells: potential promotion of 17β-estradiol biosynthesis in human placenta. Biochem. Pharmacol. 2006, 71:1349-1357.
45. Okubo T., Suzuki T., Yokoyama Y., Kano K., Kano I. Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro. Biol. Pharm. Bull. 2003, 26:1219-1224.
46. Oshima Y., Nirmala K., Go J., Yokota Y., Koyama J., Imada N., Honjyo N., Kobayashi K. High accumulation of tributyltin in blood among the tissues of fish and applicability to environmental monitoring. Environ. Toxicol. Chem. 1997, 16:1515-1517.
47. Paech K., Webb P., Kuiper G.G., Nilsson S., Gustafsson J., Kushner P.J., Scanlan T.S. Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science 1997, 277:1508-1510.
48. Park M.T., Cha H.J., Jeong J.W., Kim S.I., Chung H.Y., Kim N.D., Kim O.H., Kim K.W. Glucocorticoid receptor-induced down-regulation of MMP-9 by ginseng components, PD and PT contributes to inhibition of the invasive capacity of HT1080 human fibrosarcoma cells. Mol. Cells 1999, 9:476-483.
49. Pavlikova B.N., Trond M.K., Augustine A. Peroxisome proliferator-activated receptors, estrogenic responses and biotransformation system in the liver of salmon exposed to tributyltin and second messenger activator. Aquat. Toxicol. 2010, 99:176-185.
50. Penza M., Jeremic M., Marrazzo E., Maggi A., Ciana P., Rando G., Grigolato P.G., Lorenzo D.D. The environmental chemical Tributyltin Chloride (TBT) shows both estrogenic and adipogenic activities in mice which might depend on exposure dose. Toxicol. Appl. Pharmacol. 2011, 255:65-75.
51. Piver W.T. Organotin compounds: industrial applications and biological investigation. Environ. Health Perspect. 1973, 4:61-79.
52. Quaedackers M.E., Vanden B.C.E., Wissink S., Schreurs R.H., Gustafsson J.A., Vandersaag P.T., Vanderburg B. 4-Hydroxytamoxifen trans-represses nuclear factor-kappa activity in human osteoblastic U2-OS cells through estrogen receptor (ER) alpha, and not through ER beta. Endocrinology 2001, 142:1156-1166.
53. Radice S., Chiesara E., Frigerio S., Fumagalli R., Parolaro D., Rubino T., Marabini L. Estrogenic effect of procymidone through activation of MAPK in MCF-7 breast carcinoma cell line. Life Sci. 2006, 78:2716-2723.
54. Roberts M.H., Huggett R.J., Bender M.E., Slone H., DeLisle P.F. Tributyltin bioconcentration from solution and suspended sediments by oysters, with a comparison with uptake in 112 field experiment. Organotin: Environmental Fate and Effects 1996, 357-368. Chapman and Hall, London.
55. Russell D.W., Wilson J.D. Steroid 5α-reductase two genes/two enzymes. Annu. Rev. Biochem. 1994, 63:25-61.
56. Saitoh M., Yanase T., Morinaga H., Tanabe M., Mu Y.M., Nishi Y. Tributyltin or triphenyltin inhibits aromatase activity in the human granulosa-like tumor cell line KGN. Biochem. Biophys. Res. Commun. 2001, 289:198-204.
57. Salazar M.H., Salazar S.M. Utility of mussel growth in assessing the environmental effects of tributyltin. Proc. 3rd International Organotin Symposium, Monaco 1990, 132-136.
58. Salazar M.H., Salazar S.M. Assessing site-specific effects of TBT contamination with mussel growth rates. Mar. Environ. Res. 1991, 32:131-150.
59. Sanderson J.T., Boerma J., Gideon W.A., Lansbergen M.V. Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol. Appl. Pharmacol. 2002, 182:44-54.
60. Sharpe R.M. Pathways of endocrine disruption during male sexual differentiation and masculinisation. Best Pract Res. Clin Endocrinol Metab. 2006, 20:91-110.
61. Silva E., Kabil A., Kortenkamp A. Cross-talk between non-genomic and genomic signalling pathways distinct effect profiles of environmental estrogens. Toxicol. Appl. Pharmacol. 2010, 245:160-170.
62. Song R.X., McPherson R.A., Adam L., Bao Y., Shupnik M., Kumar R., Santen R.J. Linkage of rapid estrogen action to MAPK activation by ER_-Shc association and Shc pathway activation. Mol. Endocrinol. 2002, 16:116-127.
63. Spooner N., Gibbs P.E., Bryan G.W., Goad L.J. The effect of tributyltin upon steroid titres in the female dogwhelk, Nucella lapillus, and the development of imposex. Mar. Environ. Res. 1991, 32:37-49.
64. Stroben E., Oehlmann J., Bettin C. TBT-induced imposex and the role of steroids in marine snails 1991, 68-73. Proceedings, Tenth World Meeting of the Organotin Environmental Programme Association, Berlin, (September 26-27).
65. Takahashi S., Tanabe S., Kawaguchi K. Organochlorine and butyltin residues in mesopelagic myctophid fishes from the Western North Pacific. Environ. Sci. Technol. 2000, 34:5129-5513.
66. Tanani M.E., Green C.D. Interaction between estradiol and cAMP in the regulation of specific gene expression. Mol. Cell. Endocrinol. 1996, 124:71-77.
67. Van der Burg B., Rutteman G.R., Blankenstein M.A., de Laat S.W., van Zoelen E.J. Mitogenic stimulation of human breast cancer cells in a growth factor-defined medium: synergistic action of insulin and estrogen. J. Cell. Physiol. 1988, 134:101-108.
68. Zava D.T., Mcguire W.L. Androgen action through estrogen receptor in a human breast cancer cell line. Endocrinology 1978, 103:624-631.
69. Zhu Y.T., Liping H.C.Q., Zhu Y. PRIP promotes tumor formation through enhancing serum-responsive factor-mediated FOS expression. J. Biol. Chem. 2009, 284(21):14485-14492.