The environmental chemical tributyltin chloride (TBT) shows both estrogenic and adipogenic activities in mice which might depend on the exposure dose

Toxicology and Applied Pharmacology

Volumn 255, Issue 1, 2011, Pages 65-75

  Penza, M ^a   Jeremic, M ^a   Marrazzo, E ^a   Maggi, A ^c   Ciana, P ^c   Rando, G ^d   Grigolato, P G ^b   Di Lorenzo, D ^a  

^a Civic Hospital of Brescia   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Adipogenic chemicals; Adipose deposition; Endocrine disruptors; Estrogen receptors; Estrogen reporter mice

Indexed keywords

ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; LUCIFERASE; TRIBUTYLTIN CHLORIDE;

ADIPOSE TISSUE CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN 3T3; CONTROLLED STUDY; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC TRANSFECTION; HORMONE ACTION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PUBERTY;

3T3-L1 CELLS; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; DIETHYLSTILBESTROL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; ESTRADIOL; FEMALE; MALE; MICE; MICE, INBRED C57BL; PPAR GAMMA; RECEPTORS, ESTROGEN; TRIALKYLTIN COMPOUNDS;

MUS;

EID: 79960834955     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.05.017     Document Type: Article

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