1α,25-dihydroxyvitamin D3 exerts tissue-specific effects on estrogen and androgen metabolism

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1811, Issue 4, 2011, Pages 263-270

  Lundqvist, Johan ^a   Norlin, Maria ^a   Wikvall, Kjell ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTANOLONE; AROMATASE; CALCITRIOL; ENDOCRINE DISRUPTOR; ESTRADIOL; ESTROGEN; TESTOSTERONE;

ADRENAL CORTEX CELL; ANDROGEN METABOLISM; ANDROGEN SYNTHESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL SPECIFICITY; CELL STRAIN LNCAP; CELL STRAIN MCF 7; CONTROLLED STUDY; ENZYME ACTIVITY; ESTROGEN METABOLISM; ESTROGEN SYNTHESIS; GENE EXPRESSION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; STEROIDOGENESIS; TESTOSTERONE SYNTHESIS; TISSUE SPECIFICITY;

ADRENAL CORTEX NEOPLASMS; ANDROGENS; AROMATASE; BREAST NEOPLASMS; ESTROGENS; FEMALE; HUMANS; MALE; PROMOTER REGIONS, GENETIC; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TESTOSTERONE; TUMOR CELLS, CULTURED; VITAMIN D;

EID: 79751530495     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2011.01.004     Document Type: Article

References (33)

1. A.W. Norman From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health Am. J. Clin. Nutr. 88 2008 491S 499S
2. B. Lehmann, and M. Meurer Vitamin D metabolism Dermatol. Ther. 23 2010 2 12
3. J. Lundqvist, M. Norlin, and K. Wikvall 1α,25-Dihydroxyvitamin D3 affects hormone production and expression of steroidogenic enzymes in human adrenocortical NCI-H295R cells Biochim. Biophys. Acta BBA Mol. Cell Biol. Lipids 1801 2010 1056 1062
4. T. Gracia, K. Hilscherova, P.D. Jones, J.L. Newsted, X. Zhang, M. Hecker, E.B. Higley, J.T. Sanderson, R.M.K. Yu, R.S.S. Wu, and J.P. Giesy The H295R system for evaluation of endocrine-disrupting effects Ecotoxicol. Environ. Saf. 65 2006 293 305 (Pubitemid 44498792)
5. M. Hecker, J.L. Newsted, M.B. Murphy, E.B. Higley, P.D. Jones, R. Wu, and J.P. Giesy Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production Toxicol. Appl. Pharmacol. 217 2006 114 124 (Pubitemid 44635660)
6. E. Higley, J. Newsted, X. Zhang, J. Giesy, and M. Hecker Assessment of chemical effects on aromatase activity using the H295R cell line Environ. Sci. Pollut. Res. 17 2010 1137 1148
7. M. Hecker, H. Hollert, R. Cooper, A.-M. Vinggaard, Y. Akahori, M. Murphy, C. Nellemann, E. Higley, J. Newsted, R. Wu, P. Lam, J. Laskey, A. Buckalew, S. Grund, M. Nakai, G. Timm, and J. Giesy The OECD validation program of the H295R steroidogenesis assay for the identification of in vitro inhibitors and inducers of testosterone and estradiol production. Phase 2: inter-laboratory pre-validation studies Environ. Sci. Pollut. Res. 14 2007 23 30 (Pubitemid 46732437)
8. G.L. Christensen, J.S. Jepsen, C.K. Fog, I.J. Christensen, and A.E. Lykkesfeldt Sequential versus combined treatment of human breast cancer cells with antiestrogens and the vitamin D analogue EB1089 and evaluation of predictive markers for vitamin D treatment Breast Cancer Res. Treat. 85 2004 53 63 (Pubitemid 38437982)
9. A.V. Krishnan, S. Swami, and D. Feldman Vitamin D and breast cancer: inhibition of estrogen synthesis and signaling J. Steroid Biochem. Mol. Biol. 121 2010 343 348
10. S.S. Larsen, I. Heiberg, and A.E. Lykkesfeldt Anti-oestrogen resistant human breast cancer cell lines are more sensitive towards treatment with the vitamin D analogue EB1089 than parent MCF-7 cells Br. J. Cancer 84 2001 686 690 (Pubitemid 32239004)
11. J. Welsh Targets of vitamin D receptor signaling in the mammary gland J. Bone Miner. Res. 22 2007 V86 V90
12. B.A. Ingraham, B. Bragdon, and A. Nohe Molecular basis of the potential of vitamin D to prevent cancer Curr. Med. Res. Opin. 24 2008 139 149 (Pubitemid 351160247)
13. S. Hironobu, M. Yasuhiro, N. Shuji, and S. Takashi In situ estrogen production and its regulation in human breast carcinoma: from endocrinology to intracrinology Pathol. Int. 59 2009 777 789
14. W.R. Miller, T.J. Anderson, and W.J.L. Jack Relationship between tumour aromatase activity, tumour characteristics and response to therapy J. Steroid Biochem. Mol. Biol. 37 1990 1055 1059
15. S. Chen Aromatase and breast cancer Front. Biosci. 3 1998 d922 d933
16. D. Barrera, E. Avila, G. Hernández, A. Halhali, B. Biruete, F. Larrea, and L. Díaz Estradiol and progesterone synthesis in human placenta is stimulated by calcitriol J. Steroid Biochem. Mol. Biol. 103 2007 529 532 (Pubitemid 46401361)
17. T. Sun, Y. Zhao, D.J. Mangelsdorf, and E.R. Simpson Characterization of a region upstream of exon I.1 of the human CYP19 (aromatase) gene that mediates regulation by retinoids in human choriocarcinoma cells Endocrinology 139 1998 1684 1691 (Pubitemid 28513825)
18. Y.-R. Lou, T. Murtola, and P. Tuohimaa Regulation of aromatase and 5α-reductase by 25-hydroxyvitamin D3, 1α, 25-dihydroxyvitamin D3, dexamethasone and progesterone in prostate cancer cells J. Steroid Biochem. Mol. Biol. 94 2005 151 157 (Pubitemid 40614528)
19. S. Tanaka, M. Haji, R. Takayanagi, S. Tanaka, Y. Sugioka, and H. Nawata 1, 25-Dihydroxyvitamin D3 enhances the enzymatic activity and expression of the messenger ribonucleic acid for aromatase cytochrome P450 synergistically with dexamethasone depending on the vitamin D receptor level in cultured human osteoblasts Endocrinology 137 1996 1860 1869
20. K. Kinuta, H. Tanaka, T. Moriwake, K. Aya, S. Kato, and Y. Seino Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads Endocrinology 141 2000 1317 1324 (Pubitemid 32269098)
21. A.V. Krishnan, S. Swami, L. Peng, J. Wang, J. Moreno, and D. Feldman Tissue-selective regulation of aromatase expression by calcitriol: implications for breast cancer therapy Endocrinology 151 1 2010 32 42
22. J. Pascussi, A. Robert, M. Nguyen, O. Walrant-Debray, M. Garabedian, P. Martin, T. Pineau, J. Saric, F. Navarro, P. Maurel, and M. Vilarem Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia J. Clin. Invest. 115 2005 177 186 (Pubitemid 40385519)
23. E.S. Diaz-Cruz, C.L. Shapiro, and R.W. Brueggemeier Cyclooxygenase inhibitors suppress aromatase expression and activity in breast cancer cells J. Clin. Endocrinol. Metab. 90 2005 2563 2570 (Pubitemid 40686292)
24. T. Suzuki, A.D. Darnel, J.-I. Akahira, N. Ariga, S. Ogawa, C. Kaneko, J. Takeyama, T. Moriya, and H. Sasano 5α-Reductases in human breast carcinoma: possible modulator of in situ androgenic actions J. Clin. Endocrinol. Metab. 86 2001 2250 2257 (Pubitemid 32472948)
25. M. Matilainen, M. Malinen, K. Saavalainen, and C. Carlberg Regulation of multiple insulin-like growth factor binding protein genes by 1{alpha}, 25-dihydroxyvitamin D3 Nucl. Acids Res. 33 2005 5521 5532 (Pubitemid 41548818)
26. M.-s. Kim, R. Fujiki, A. Murayama, H. Kitagawa, K. Yamaoka, Y. Yamamoto, M. Mihara, K.-i. Takeyama, and S. Kato 1{Alpha},25(OH)2D3-induced transrepression by vitamin D receptor through E-box-type elements in the human parathyroid hormone gene promoter Mol. Endocrinol. 21 2007 334 342 (Pubitemid 46188281)
27. M. Ellfolk, M. Norlin, K. Gyllensten, and K. Wikvall Regulation of human vitamin D3 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells Mol. Pharmacol. 75 2009 1392 1399
28. L.L. Ooi, Y. Zheng, H. Zhou, T. Trivedi, A.D. Conigrave, M.J. Seibel, C.R. Dunstan, Vitamin D deficiency promotes growth of MCF-7 human breast cancer in a rodent model of osteosclerotic bone metastasis, Bone 47 795.
29. W. Miller Steroidogenic enzymes Endocr. Dev. 13 2008 1 18
30. W.L. Miller, R.J. Auchus, and D.H. Geller The regulation of 17, 20 lyase activity Steroids 62 1997 133 142
31. P.F. Hall Cytochrome P-450 C21scc: one enzyme with two actions: hydroxylase and lyase J. Steroid Biochem. Mol. Biol. 40 1991 527 532
32. S.E. Bulun, Z. Lin, H. Zhao, M. Lu, S. Amin, S. Reierstad, and D. Chen Regulation of aromatase expression in breast cancer tissue Ann. NY Acad. Sci. 1155 2009 121 131
33. E.R. Simpson, C. Clyne, G. Rubin, W.C. Boon, K. Robertson, K. Britt, C. Speed, and M. Jones Aromatase-a brief overview Annu. Rev. Physiol. 64 2002 93 127