메뉴 건너뛰기




Volumn 58, Issue 3, 2013, Pages 759-767

Analysis of genetic damage and gene polymorphism in hepatocellular carcinoma (HCC) patients in a South Indian population

Author keywords

Chromosomal alterations; Genotypic analysis; Hepatocellular carcinoma; Micronucleus; p53; XRCC1

Indexed keywords

ALPHA FETOPROTEIN; PROTEIN P53; XRCC1 PROTEIN;

EID: 84876675276     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2409-8     Document Type: Article
Times cited : (22)

References (74)
  • 1
    • 33645270580 scopus 로고    scopus 로고
    • Natural history of hepatocellular carcinoma
    • 16154825 10.1102/1470-7330.2005.0014
    • Colombo M. Natural history of hepatocellular carcinoma. Cancer Imaging. 2005;5:85-88.
    • (2005) Cancer Imaging , vol.5 , pp. 85-88
    • Colombo, M.1
  • 2
    • 33645787044 scopus 로고    scopus 로고
    • Hepatocellular carcinoma. An overview
    • 16531960 1:CAS:528:DC%2BD28XjtlWltbY%3D
    • Motola Kuba D, Zamora Valdes D, Uribe M, et al. Hepatocellular carcinoma. An overview. Ann Hepatol. 2006;5:16-24.
    • (2006) Ann Hepatol , vol.5 , pp. 16-24
    • Motola Kuba, D.1    Zamora Valdes, D.2    Uribe, M.3
  • 3
    • 36849048122 scopus 로고    scopus 로고
    • Liver transplantation for hepatocellular carcinoma in Asia
    • 10.1634/theoncologist.12-11-1321
    • Villa VD, Lo CM. Liver transplantation for hepatocellular carcinoma in Asia. Oncologist. 2007;12:132-1331.
    • (2007) Oncologist , vol.12 , pp. 132-1331
    • Villa, V.D.1    Lo, C.M.2
  • 4
    • 38049112379 scopus 로고    scopus 로고
    • Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cells
    • Bu X, Jia F, Wang W, et al. Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cells. Bio Med Central Cancer. 2007;7:208-215.
    • (2007) Bio Med Central Cancer , vol.7 , pp. 208-215
    • Bu, X.1    Jia, F.2    Wang, W.3
  • 5
    • 38349028891 scopus 로고    scopus 로고
    • Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model
    • 18161924 10.3748/wjg.13.6538
    • Chakraborty T, Bhuniya D, Chatterjee M, et al. Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model. World J Gastroenterol. 2007;13:6538-6548.
    • (2007) World J Gastroenterol , vol.13 , pp. 6538-6548
    • Chakraborty, T.1    Bhuniya, D.2    Chatterjee, M.3
  • 6
    • 84876669804 scopus 로고    scopus 로고
    • Penn State Milton S. Hershey Medical Center College of Medicine/Malignant Hepatoma Accessed January 15, 2008
    • Penn State Milton S. Hershey Medical Center College of Medicine/Malignant Hepatoma. Available at: http://www.hmc.psu.edu/healthinfo/m/malignanthepatoma. htm. Accessed January 15, 2008.
  • 7
    • 43749086456 scopus 로고    scopus 로고
    • Racial and ethnic variations in hepatocellular carcinoma incidence within the United States
    • 18501235 10.1016/j.amjmed.2008.03.005
    • Wong R, Corley DA. Racial and ethnic variations in hepatocellular carcinoma incidence within the United States. Am J Med. 2008;121:525-531.
    • (2008) Am J Med , vol.121 , pp. 525-531
    • Wong, R.1    Corley, D.A.2
  • 8
    • 0642310849 scopus 로고    scopus 로고
    • Predictors and patterns of recurrence after resection of hepatocellular carcinoma
    • 14585409 10.1016/j.jamcollsurg.2003.07.003
    • Cha C, Fong Y, Jarnagin WR, et al. Predictors and patterns of recurrence after resection of hepatocellular carcinoma. J Am Coll Surg. 2003;197:753-758.
    • (2003) J Am Coll Surg , vol.197 , pp. 753-758
    • Cha, C.1    Fong, Y.2    Jarnagin, W.R.3
  • 9
    • 0028180445 scopus 로고
    • Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma
    • 7506227 10.1002/hep.1840190111 1:STN:280:DyaK2c7gt1Ojuw%3D%3D
    • Oka H, Tamori A, Kuroki T, et al. Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma. Hepatology. 1994;19:61-66.
    • (1994) Hepatology , vol.19 , pp. 61-66
    • Oka, H.1    Tamori, A.2    Kuroki, T.3
  • 10
    • 34548088353 scopus 로고    scopus 로고
    • Liver transplantation for hepatocellular carcinoma: Prognostic analysis of 89 cases
    • 15854372
    • Zheng SS, Xu X, Liang TB, et al. Liver transplantation for hepatocellular carcinoma: prognostic analysis of 89 cases. Zhonghua Wai Ke Za Zhi. 2005;43:450-454.
    • (2005) Zhonghua Wai Ke Za Zhi , vol.43 , pp. 450-454
    • Zheng, S.S.1    Xu, X.2    Liang, T.B.3
  • 11
    • 59349121857 scopus 로고    scopus 로고
    • The value of serum a-fetoprotein in predicting tumor recurrence after liver transplantation for hepatocellular carcinoma
    • 18563566 10.1007/s10620-008-0349-0 1:CAS:528:DC%2BD1MXhtlOqtbo%3D
    • Xu X, Ke QH, Shao Z-X, et al. The value of serum a-fetoprotein in predicting tumor recurrence after liver transplantation for hepatocellular carcinoma. Dig Dis Sci. 2009;54:385-388.
    • (2009) Dig Dis Sci , vol.54 , pp. 385-388
    • Xu, X.1    Ke, Q.H.2    Shao, Z.-X.3
  • 12
    • 0034255796 scopus 로고    scopus 로고
    • IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans
    • 10913908 10.1016/S1383-5742(00)00049-1 1:CAS:528:DC%2BD3cXltVKjt7k%3D
    • Albertini RJ, Anderson D, Douglas GR, et al. IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. Mutat Res. 2000;463:111-172.
    • (2000) Mutat Res , vol.463 , pp. 111-172
    • Albertini, R.J.1    Anderson, D.2    Douglas, G.R.3
  • 14
    • 0032530829 scopus 로고    scopus 로고
    • Chromosomal aberrations in lymphocytes predict human cancer: A report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH)
    • 9751622 1:CAS:528:DyaK1cXmtlCks7s%3D
    • Hagmar LS, Bonassi U, Strömberg A, et al. Chromosomal aberrations in lymphocytes predict human cancer: a report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH). Cancer Res. 1998;58:4117-4121.
    • (1998) Cancer Res , vol.58 , pp. 4117-4121
    • Hagmar, L.S.1    Bonassi, U.2    Strömberg, A.3
  • 15
    • 0034653699 scopus 로고    scopus 로고
    • European Study Group on cytogenetic biomarkers and health. Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens
    • 10749131 1:CAS:528:DC%2BD3cXit1aqtL8%3D
    • Bonassi S, Hagmar L, Strömberg U, et al. European Study Group on cytogenetic biomarkers and health. Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens. Cancer Res. 2000;60:1619-1625.
    • (2000) Cancer Res , vol.60 , pp. 1619-1625
    • Bonassi, S.1    Hagmar, L.2    Strömberg, U.3
  • 16
    • 34047154552 scopus 로고    scopus 로고
    • An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans
    • Bonassi S, Znaor A, Ceppi C, et al. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis. 2007;28:331-338.
    • (2007) Carcinogenesis , vol.28 , pp. 331-338
    • Bonassi, S.1    Znaor, A.2    Ceppi, C.3
  • 17
    • 0001891734 scopus 로고    scopus 로고
    • Molecular genetic alterations in primary hepatocellular neoplasms: Hepatocellular adenoma, hepatocellular carcinoma, and hepatoblastoma
    • W.B. Coleman G.J. Tsongalis (eds) Humana Press Inc. Totowa
    • Grisham JW. Molecular genetic alterations in primary hepatocellular neoplasms: hepatocellular adenoma, hepatocellular carcinoma, and hepatoblastoma. In: Coleman WB, Tsongalis GJ, eds. The Molecular Basis of Human Cancer. Totowa: Humana Press Inc.; 2002:269-346.
    • (2002) The Molecular Basis of Human Cancer , pp. 269-346
    • Grisham, J.W.1
  • 18
    • 0036699940 scopus 로고    scopus 로고
    • Molecular pathogenesis of human hepatocellular carcinoma
    • 12149612 10.1038/ng0802-339 1:CAS:528:DC%2BD38Xls1Oku7c%3D
    • Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet. 2002;31:339-346.
    • (2002) Nat Genet , vol.31 , pp. 339-346
    • Thorgeirsson, S.S.1    Grisham, J.W.2
  • 19
    • 33748421506 scopus 로고    scopus 로고
    • Molecular karyotyping of human hepatocellular carcinoma using single-nucleotide polymorphism arrays
    • 16785998 10.1038/sj.onc.1209537 1:CAS:528:DC%2BD28XptFCmuro%3D
    • Midorikawa Y, Yamamoto S, Ishikawa S, et al. Molecular karyotyping of human hepatocellular carcinoma using single-nucleotide polymorphism arrays. Oncogene. 2006;25:5581-5590.
    • (2006) Oncogene , vol.25 , pp. 5581-5590
    • Midorikawa, Y.1    Yamamoto, S.2    Ishikawa, S.3
  • 20
    • 70350380976 scopus 로고    scopus 로고
    • Cytogenetic analysis of benign prostate hyperplasia (BPH) and prostate cancer (PC) patients from Tamil Nadu, South India
    • Balachandar V, Mohana Devi S, Lakshman Kumar B, et al. Cytogenetic analysis of benign prostate hyperplasia (BPH) and prostate cancer (PC) patients from Tamil Nadu, South India. Sci Res Essay (Academic Journal Publication). 2008;3:212-214.
    • (2008) Sci Res Essay (Academic Journal Publication) , vol.3 , pp. 212-214
    • Balachandar, V.1    Mohana Devi, S.2    Lakshman Kumar, B.3
  • 21
    • 79955366082 scopus 로고    scopus 로고
    • Identification of chromosomal aberrations by using trypsin G- banding in hepatocellular carcinoma patients (HCC) in Tamilnadu, India
    • Mohana Devi S, Balachandar V, Vel Murugan P, et al. Identification of chromosomal aberrations by using trypsin G- banding in hepatocellular carcinoma patients (HCC) in Tamilnadu, India. Trop Life Sci Res. 2010;21:33-49.
    • (2010) Trop Life Sci Res , vol.21 , pp. 33-49
    • Mohana Devi, S.1    Balachandar, V.2    Vel Murugan, P.3
  • 22
    • 0033755177 scopus 로고    scopus 로고
    • Genomic aberrations in human hepatocellular carcinomas of differing etiologies
    • 11051249 1:CAS:528:DC%2BD3cXotVykurg%3D
    • Wong N, Lai P, Pang E, et al. Genomic aberrations in human hepatocellular carcinomas of differing etiologies. Clin Cancer Res. 2000;6:4000-4009.
    • (2000) Clin Cancer Res , vol.6 , pp. 4000-4009
    • Wong, N.1    Lai, P.2    Pang, E.3
  • 23
    • 0034909856 scopus 로고    scopus 로고
    • Selective inactivation of p53 facilitates mouse epithelial tumor progression without chromosomal instability
    • 11486039 10.1128/MCB.21.17.6017-6030.2001 1:CAS:528:DC%2BD3MXlvF2htLg%3D
    • Lu XG, Magrane C, Yin DN, et al. Selective inactivation of p53 facilitates mouse epithelial tumor progression without chromosomal instability. Mol Cell Biol. 2001;21:6017-6030.
    • (2001) Mol Cell Biol , vol.21 , pp. 6017-6030
    • Lu, X.G.1    Magrane, C.2    Yin, D.N.3
  • 24
    • 0037714871 scopus 로고    scopus 로고
    • Is p53 gene mutation an indicator of the biological behaviors of recurrence of hepatocellular carcinoma?
    • 12800224 1:CAS:528:DC%2BD3sXlvVSrurs%3D
    • Sheen IS, Jeng KS, Wu JY, et al. Is p53 gene mutation an indicator of the biological behaviors of recurrence of hepatocellular carcinoma? World J Gastroenterol. 2003;9:1202-1207.
    • (2003) World J Gastroenterol , vol.9 , pp. 1202-1207
    • Sheen, I.S.1    Jeng, K.S.2    Wu, J.Y.3
  • 25
    • 0037222429 scopus 로고    scopus 로고
    • TP53 and liver carcinogenesis
    • 12619106 10.1002/humu.10176 1:CAS:528:DC%2BD3sXis1yjtro%3D
    • Staib F, Hussain SP, Hofseth LJ, et al. TP53 and liver carcinogenesis. Hum Mutat. 2003;21:201-216.
    • (2003) Hum Mutat , vol.21 , pp. 201-216
    • Staib, F.1    Hussain, S.P.2    Hofseth, L.J.3
  • 26
    • 0033955346 scopus 로고    scopus 로고
    • XRCC1 keeps DNA from getting stranded
    • 10677679 10.1016/S0921-8777(99)00058-0 1:CAS:528:DC%2BD3cXhtFaks7s%3D
    • Thompson LH, West MG. XRCC1 keeps DNA from getting stranded. Mutat Res. 2000;459:1-18.
    • (2000) Mutat Res , vol.459 , pp. 1-18
    • Thompson, L.H.1    West, M.G.2
  • 27
    • 0034098801 scopus 로고    scopus 로고
    • Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells
    • 10.1093/carcin/21.5.965 1:CAS:528:DC%2BD3cXjsFyht7g%3D
    • Duell EJ, Wiencke JK, Cheng TJ, et al. Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells. Carcinogenesis Lond. 2000;21:965-971.
    • (2000) Carcinogenesis Lond , vol.21 , pp. 965-971
    • Duell, E.J.1    Wiencke, J.K.2    Cheng, T.J.3
  • 28
    • 80053506830 scopus 로고    scopus 로고
    • XRCC1 genetic polymorphism Arg399Gln and hepatocellular carcinoma risk: A meta-analysis
    • 10.1111/j.1478-3231.2011.02508.x
    • Liu F, Li B, Wei Y, Yan L, et al. XRCC1 genetic polymorphism Arg399Gln and hepatocellular carcinoma risk: a meta-analysis. Liver Int. 2011;6:802-809.
    • (2011) Liver Int , vol.6 , pp. 802-809
    • Liu, F.1    Li, B.2    Wei, Y.3    Yan, L.4
  • 29
    • 1542322897 scopus 로고    scopus 로고
    • Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis
    • 14672555 10.1038/sj.cr.7290177 1:CAS:528:DC%2BD2cXhsFWitb0%3D
    • Yu J, Zhang HY, Ma ZZ, et al. Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis. Cell Res. 2003;13:319-333.
    • (2003) Cell Res , vol.13 , pp. 319-333
    • Yu, J.1    Zhang, H.Y.2    Ma, Z.Z.3
  • 30
    • 0035846899 scopus 로고    scopus 로고
    • XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair
    • 11163244 10.1016/S0092-8674(01)00195-7 1:CAS:528:DC%2BD3MXis1Oqs7w%3D
    • Whitehouse CJ, Taylor RM, Thistlethwaite A. XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair. Cell. 2001;104:107-117.
    • (2001) Cell , vol.104 , pp. 107-117
    • Whitehouse, C.J.1    Taylor, R.M.2    Thistlethwaite, A.3
  • 31
    • 0013663724 scopus 로고
    • Chromosome preparations of leukocytes cultured from peripheral blood
    • 13772379 10.1016/0014-4827(60)90138-5 1:STN:280:DyaF3c%2Fpt1Cmtw%3D%3D
    • Moorhead PS, Novell WJ, Mellman DM, et al. Chromosome preparations of leukocytes cultured from peripheral blood. Exp Cell Res. 1960;20:613-616.
    • (1960) Exp Cell Res , vol.20 , pp. 613-616
    • Moorhead, P.S.1    Novell, W.J.2    Mellman, D.M.3
  • 32
    • 84876692231 scopus 로고    scopus 로고
    • Altman Statistics Notes: The odds ratio
    • 10.1136/bmj.320.7247.1468
    • Martin Bland J, Douglas G. Altman Statistics Notes: the odds ratio. BMJ. 2000;320:1468.
    • (2000) BMJ , vol.320 , pp. 1468
    • Martin Bland, J.1    Douglas, G.2
  • 33
    • 0038777498 scopus 로고    scopus 로고
    • 15 million new cancer cases per year by 2020, says WHO
    • 12699963 10.1016/S0140-6736(03)13038-3
    • Frankish H. 15 million new cancer cases per year by 2020, says WHO. Lancet. 2003;361:1278.
    • (2003) Lancet , vol.361 , pp. 1278
    • Frankish, H.1
  • 34
    • 63049133092 scopus 로고    scopus 로고
    • Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
    • 19224838 10.1200/JCO.2008.20.7753
    • Altekruse SF, McGlynn KA, Reichman ME. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J Clin Oncol. 2009;27:1485-1491.
    • (2009) J Clin Oncol , vol.27 , pp. 1485-1491
    • Altekruse, S.F.1    McGlynn, K.A.2    Reichman, M.E.3
  • 35
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • 2188735 10.1016/0092-8674(90)90186-I 1:CAS:528:DyaK3cXktlyhtrg%3D
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61:759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 36
    • 33947204625 scopus 로고    scopus 로고
    • Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma
    • 17317821 10.1158/1078-0432.CCR-06-1025 1:CAS:528:DC%2BD2sXhvF2hsLs%3D
    • Jia HL, Ye QH, Qin LX. Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma. Clin Cancer Res. 2007;13:1133.
    • (2007) Clin Cancer Res , vol.13 , pp. 1133
    • Jia, H.L.1    Ye, Q.H.2    Qin, L.X.3
  • 37
    • 0033541491 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • 10217098 10.1016/S0140-6736(98)09148-X 1:STN:280:DyaK1M3jtFCmsg%3D%3D
    • Schafer DF, Sorrell MF. Hepatocellular carcinoma. Lancet. 1999;353:1253-1257.
    • (1999) Lancet , vol.353 , pp. 1253-1257
    • Schafer, D.F.1    Sorrell, M.F.2
  • 38
    • 3242779196 scopus 로고    scopus 로고
    • A-Fetoprotein impairs APC function and induces their apoptosis
    • 15265907 1:CAS:528:DC%2BD2cXlvVajsL8%3D
    • Um SH, Mulhall C, Alisa A. a-Fetoprotein impairs APC function and induces their apoptosis. J Immunol. 2004;173:1772-1778.
    • (2004) J Immunol , vol.173 , pp. 1772-1778
    • Um, S.H.1    Mulhall, C.2    Alisa, A.3
  • 39
    • 0022163173 scopus 로고
    • The structure and regulation of the a-fetoprotein and albumin genes
    • 2474300 1:CAS:528:DyaL2sXkvFSqur0%3D
    • Tilghman SM. The structure and regulation of the a-fetoprotein and albumin genes. Oxf Surv Eukaryot Genes. 1985;2:160-206.
    • (1985) Oxf Surv Eukaryot Genes , vol.2 , pp. 160-206
    • Tilghman, S.M.1
  • 40
    • 34250319273 scopus 로고    scopus 로고
    • Specific molecular markers in hepatocellular carcinoma
    • 17548245 1:CAS:528:DC%2BD2sXns1KgtLc%3D
    • Yao DF, Dong ZZ, Yao M. Specific molecular markers in hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int. 2007;6:241-247.
    • (2007) Hepatobiliary Pancreat Dis Int , vol.6 , pp. 241-247
    • Yao, D.F.1    Dong, Z.Z.2    Yao, M.3
  • 41
    • 0023676812 scopus 로고
    • Analysis of alpha-fetoprotein gene expression in hepatocellular carcinoma and liver cirrhosis by in situ hybridization
    • 2457423 10.1002/1097-0142(19880915)62:6<1105: AID-CNCR2820620613>3. 0.CO;2-Z 1:STN:280:DyaL1czhtVOmtQ%3D%3D
    • Otsuru A, Nagataki S, Koji T, et al. Analysis of alpha-fetoprotein gene expression in hepatocellular carcinoma and liver cirrhosis by in situ hybridization. Cancer. 1988;62:1105-1112.
    • (1988) Cancer , vol.62 , pp. 1105-1112
    • Otsuru, A.1    Nagataki, S.2    Koji, T.3
  • 42
    • 0025696558 scopus 로고
    • α-fetoprotein: Reevaluation in hepatology
    • 1701754 10.1002/hep.1840120625 1:CAS:528:DyaK3MXkvV2qtbY%3D
    • Taketa K. α-fetoprotein: reevaluation in hepatology. Hepatology. 1990;12:1420-1432.
    • (1990) Hepatology , vol.12 , pp. 1420-1432
    • Taketa, K.1
  • 43
    • 0034992615 scopus 로고    scopus 로고
    • Alpha-fetoprotein structure and function: Relevance to isoforms, epitomes, and conformational variants
    • 1:CAS:528:DC%2BD3MXjtlGgur8%3D
    • Mizejewski GJ. Alpha-fetoprotein structure and function: relevance to isoforms, epitomes, and conformational variants. Exp Biol Med. 2001;226:377-408.
    • (2001) Exp Biol Med , vol.226 , pp. 377-408
    • Mizejewski, G.J.1
  • 45
    • 0032484502 scopus 로고    scopus 로고
    • Allelotype analysis of hepatocellular carcinoma
    • 9426686 10.1002/(SICI)1097-0215(19980105)75:1<29: AID-IJC5>3.0. CO;2-3 1:STN:280:DyaK1c%2FovVSqsA%3D%3D
    • Piao Z, Park C, Park JH, Kim H. Allelotype analysis of hepatocellular carcinoma. Int J Cancer. 1998;75:29-33.
    • (1998) Int J Cancer , vol.75 , pp. 29-33
    • Piao, Z.1    Park, C.2    Park, J.H.3    Kim, H.4
  • 46
    • 0033843955 scopus 로고    scopus 로고
    • Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization
    • 10959090 10.1002/1098-2264(2000)9999:9999<: AID-GCC1022>3.0.CO;2-V 1:CAS:528:DC%2BD3cXntVWiur0%3D
    • Guan XY, Fang Y, Sham JS, et al. Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer. 2000;29:110-116.
    • (2000) Genes Chromosomes Cancer , vol.29 , pp. 110-116
    • Guan, X.Y.1    Fang, Y.2    Sham, J.S.3
  • 47
    • 0037190125 scopus 로고    scopus 로고
    • Assessment of chromosomal losses and gains in hepatocellular carcinoma
    • 12048165 10.1016/S0304-3835(02)00083-6 1:CAS:528:DC%2BD38XktFKgsrk%3D
    • Chang J, Kim NG, Piao Z, et al. Assessment of chromosomal losses and gains in hepatocellular carcinoma. Cancer Lett. 2002;182:193-202.
    • (2002) Cancer Lett , vol.182 , pp. 193-202
    • Chang, J.1    Kim, N.G.2    Piao, Z.3
  • 48
    • 84984532070 scopus 로고    scopus 로고
    • Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma
    • 15126338 10.1158/0008-5472.CAN-03-2320 1:CAS:528:DC%2BD2cXjs1ehsbg%3D
    • Jou YS, Lee CS, Chang YH. Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma. Cancer Res. 2004;64:3030-3036.
    • (2004) Cancer Res , vol.64 , pp. 3030-3036
    • Jou, Y.S.1    Lee, C.S.2    Chang, Y.H.3
  • 49
    • 0033754704 scopus 로고    scopus 로고
    • 11050057 10.1053/jhep.2000.19349 1:CAS:528:DC%2BD3cXot1Wns74%3D
    • Wong N, Lai P, Pang E. Hepatology. 2000;32:1060-1068.
    • (2000) Hepatology , vol.32 , pp. 1060-1068
    • Wong, N.1    Lai, P.2    Pang, E.3
  • 50
    • 0035446479 scopus 로고    scopus 로고
    • Frequent genomic imbalances suggest commonly altered tumour genes in human hepatocarcinogenesis
    • 11531255 10.1054/bjoc.2001.1963 1:CAS:528:DC%2BD3MXns1yktrw%3D
    • Niketeghad F, Decker HJ, Caselmann WH, et al. Frequent genomic imbalances suggest commonly altered tumour genes in human hepatocarcinogenesis. Br J Cancer. 2001;85:697-704.
    • (2001) Br J Cancer , vol.85 , pp. 697-704
    • Niketeghad, F.1    Decker, H.J.2    Caselmann, W.H.3
  • 51
    • 84983725887 scopus 로고    scopus 로고
    • Chromosomal allelic imbalance evolving from liver cirrhosis to hepatocellular carcinoma
    • 11522754 10.1053/gast.2001.27211 1:STN:280:DC%2BD3MvnvFSlsQ%3D%3D
    • Yeh SH, Chen PJ, Shau WY, et al. Chromosomal allelic imbalance evolving from liver cirrhosis to hepatocellular carcinoma. Gastroenterology. 2001;121:699-709.
    • (2001) Gastroenterology , vol.121 , pp. 699-709
    • Yeh, S.H.1    Chen, P.J.2    Shau, W.Y.3
  • 52
    • 0034995765 scopus 로고    scopus 로고
    • Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis
    • 11375957 10.1053/gast.2001.24798 1:CAS:528:DC%2BD3MXkslGku7Y%3D
    • Laurent-Puig P, Legoix P, Bluteau O, et al. Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis. Gastroenterology. 2001;120:1763-1773.
    • (2001) Gastroenterology , vol.120 , pp. 1763-1773
    • Laurent-Puig, P.1    Legoix, P.2    Bluteau, O.3
  • 53
    • 27944491603 scopus 로고    scopus 로고
    • Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and JAB1 as a potential target for 8q gain in hepatocellular carcinoma
    • Patil MA, Gutgemann I, Zhang J, et al. Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and JAB1 as a potential target for 8q gain in hepatocellular carcinoma. Carcinogenesis. 2005;26:2050-2057.
    • (2005) Carcinogenesis , vol.26 , pp. 2050-2057
    • Patil, M.A.1    Gutgemann, I.2    Zhang, J.3
  • 54
    • 0030733924 scopus 로고    scopus 로고
    • Molecular mechanism of hepatocarcinogenesis
    • 9407351 10.1111/j.1440-1746.1997.tb00514.x 1:CAS:528:DyaK2sXnvFKqtLc%3D
    • Sheu JC. Molecular mechanism of hepatocarcinogenesis. J Gastroenterol Hepatol. 1997;12:S309-S313.
    • (1997) J Gastroenterol Hepatol , vol.12
    • Sheu, J.C.1
  • 55
    • 0027722263 scopus 로고
    • Micronucleus assay in lymphocytes as a tool to biomonitor human exposure to aneuploidogens and clastogens
    • 8143606 1:CAS:528:DyaK2cXntV2msg%3D%3D
    • Norppa H, Luomahaara S, Heikanen H, et al. Micronucleus assay in lymphocytes as a tool to biomonitor human exposure to aneuploidogens and clastogens. Environ Health Perspect. 1993;101:139-143.
    • (1993) Environ Health Perspect , vol.101 , pp. 139-143
    • Norppa, H.1    Luomahaara, S.2    Heikanen, H.3
  • 56
    • 34250187067 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay
    • Fenech M. Cytokinesis-block micronucleus assay. Nature Protocols. 2007;2:1084-1104.
    • (2007) Nature Protocols , vol.2 , pp. 1084-1104
    • Fenech, M.1
  • 57
    • 1642362441 scopus 로고    scopus 로고
    • Carrilhod, Shigueko Sonoharae, Detection of micronuclei formation and nuclear anomalies in regenerative nodules of human cirrhotic livers and relationship to hepatocellular carcinoma
    • 15041218 10.1016/j.cancergencyto.2003.08.001
    • de Almeida TMB, Leitao RC, et al. Carrilhod, Shigueko Sonoharae, Detection of micronuclei formation and nuclear anomalies in regenerative nodules of human cirrhotic livers and relationship to hepatocellular carcinoma. Cancer Genet Cytogenet. 2004;150:16-21.
    • (2004) Cancer Genet Cytogenet , vol.150 , pp. 16-21
    • De Almeida, T.M.B.1    Leitao, R.C.2
  • 58
    • 34047154552 scopus 로고    scopus 로고
    • An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans
    • 16973674 10.1093/carcin/bgl177 1:CAS:528:DC%2BD2sXjslOnsrg%3D
    • Bonassi S, Znaor A, Ceppi M, et al. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis. 2007;28:625-631.
    • (2007) Carcinogenesis , vol.28 , pp. 625-631
    • Bonassi, S.1    Znaor, A.2    Ceppi, M.3
  • 59
    • 0025273322 scopus 로고
    • Micronuclei in cytokinesis blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy
    • 1968501 10.1080/09553009014552471 1:STN:280:DyaK3c7ntFOitg%3D%3D
    • Fenech M, Denham J, Francis W, Morely A. Micronuclei in cytokinesis blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy. Int J Radiat Biol. 1990;57:373-383.
    • (1990) Int J Radiat Biol , vol.57 , pp. 373-383
    • Fenech, M.1    Denham, J.2    Francis, W.3    Morely, A.4
  • 60
    • 0026320743 scopus 로고
    • Micronuclei in human lymphocytes irradiated in vitro or in vivo
    • 1961924 10.2307/3578050 1:STN:280:DyaK38%2FntlGrsg%3D%3D
    • Gantenberg HW, Wuttke K, Streffer C, Muller WU. Micronuclei in human lymphocytes irradiated in vitro or in vivo. Radiat Res. 1991;128:276-281.
    • (1991) Radiat Res , vol.128 , pp. 276-281
    • Gantenberg, H.W.1    Wuttke, K.2    Streffer, C.3    Muller, W.U.4
  • 61
    • 0037194639 scopus 로고    scopus 로고
    • Increased chromosomal alterations and micronuclei formation in human hepatoma HepG2 cells transfected with the hepatitis B virus HBX gene
    • 12175906 10.1016/S0027-5107(02)00140-9 1:CAS:528:DC%2BD38XmtlGqsr8%3D
    • Livezey KW, Negorev D, Simon D. Increased chromosomal alterations and micronuclei formation in human hepatoma HepG2 cells transfected with the hepatitis B virus HBX gene. Mutat Res. 2002;505:63-74.
    • (2002) Mutat Res , vol.505 , pp. 63-74
    • Livezey, K.W.1    Negorev, D.2    Simon, D.3
  • 62
    • 0034066102 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils
    • 10792021 10.1093/mutage/15.3.261 1:CAS:528:DC%2BD3cXjs1CqtLk%3D
    • Umegaki K, Fenech M. Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis. 2000;15:261-269.
    • (2000) Mutagenesis , vol.15 , pp. 261-269
    • Umegaki, K.1    Fenech, M.2
  • 63
    • 0017059028 scopus 로고
    • The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes
    • 796719 10.1016/0027-5107(76)90105-6 1:STN:280:DyaE2s7gtVWisw%3D%3D
    • Countryman PI, Heddle JA. The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes. Mutat Res. 1976;41:321-332.
    • (1976) Mutat Res , vol.41 , pp. 321-332
    • Countryman, P.I.1    Heddle, J.A.2
  • 64
    • 0024332230 scopus 로고
    • In vivo micronucleus test using mouse hepatocytes
    • 2601732 10.1016/0165-1161(89)90042-3 1:CAS:528:DyaK3cXltVWjtg%3D%3D
    • Cliet I, Fournier E, Melcion C, et al. In vivo micronucleus test using mouse hepatocytes. Mutat Res. 1989;216:321-326.
    • (1989) Mutat Res , vol.216 , pp. 321-326
    • Cliet, I.1    Fournier, E.2    Melcion, C.3
  • 65
    • 0027448914 scopus 로고
    • Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis
    • 8242871 10.1093/carcin/14.11.2397
    • Van Goethem F, Ghahroudi MA, Castelain P, et al. Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis. Carcinogenesis. 1993;14:2397-2406.
    • (1993) Carcinogenesis , vol.14 , pp. 2397-2406
    • Van Goethem, F.1    Ghahroudi, M.A.2    Castelain, P.3
  • 66
    • 0032785259 scopus 로고    scopus 로고
    • The Human MicroNucleus Project - An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans
    • 10517999 10.1016/S1383-5742(99)00053-8 1:CAS:528:DyaK1MXltlCqsb8%3D
    • Fenech M, Holland N, Chang WP, et al. The Human MicroNucleus Project - an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat Res. 1999;428:271-283.
    • (1999) Mutat Res , vol.428 , pp. 271-283
    • Fenech, M.1    Holland, N.2    Chang, W.P.3
  • 67
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • 10647931 10.1016/S0092-8674(00)81683-9 1:CAS:528:DC%2BD3cXks1CktA%3D%3D
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 68
    • 0025828517 scopus 로고
    • Selective G to T mutations of p53gene in hepatocellular carcinoma from southern Africa
    • 1672732 10.1038/350429a0 1:CAS:528:DyaK3MXitVSqs7k%3D
    • Bressac B, Kew M, Wands J, Ozturk M. Selective G to T mutations of p53gene in hepatocellular carcinoma from southern Africa. Nature. 1991;350:429-431.
    • (1991) Nature , vol.350 , pp. 429-431
    • Bressac, B.1    Kew, M.2    Wands, J.3    Ozturk, M.4
  • 69
    • 34548292501 scopus 로고    scopus 로고
    • Base excision repair modulation as a risk factor for human cancers
    • 17628657 10.1016/j.mam.2007.05.003 1:CAS:528:DC%2BD2sXpvF2ktrw%3D
    • Tudek B. Base excision repair modulation as a risk factor for human cancers. Mol Aspects Med. 2007;28:258-275.
    • (2007) Mol Aspects Med , vol.28 , pp. 258-275
    • Tudek, B.1
  • 70
    • 33749547377 scopus 로고    scopus 로고
    • Heritable susceptibility factors for the development of cancer
    • 10.1269/jrr.47.B13
    • Au WW. Heritable susceptibility factors for the development of cancer. J Radiat Res. 2006;47:13-17.
    • (2006) J Radiat Res , vol.47 , pp. 13-17
    • Au, W.W.1
  • 71
    • 33748300692 scopus 로고    scopus 로고
    • DNA damage repair and genetic polymorphisms: Assessment of individual sensitivity and repair capacity
    • 16965996 10.1016/j.ijrobp.2006.06.037 1:CAS:528:DC%2BD28XptlyqsLo%3D
    • Cornetta T, Festa F, Testa A, Cozzi R. DNA damage repair and genetic polymorphisms: assessment of individual sensitivity and repair capacity. Int J Radiat Oncol Biol Phys. 2006;66:537-545.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 537-545
    • Cornetta, T.1    Festa, F.2    Testa, A.3    Cozzi, R.4
  • 72
    • 40449134605 scopus 로고    scopus 로고
    • XRCC1 and XPD gene polymorphisms in a South Indian population
    • 1:STN:280:DC%2BD2svotVKntA%3D%3D
    • Vettriselvi V, Vijayalakshmi K, Solomon PF. XRCC1 and XPD gene polymorphisms in a South Indian population. Asian Pac J Cancer. 2007;8:283-286.
    • (2007) Asian Pac J Cancer , vol.8 , pp. 283-286
    • Vettriselvi, V.1    Vijayalakshmi, K.2    Solomon, P.F.3
  • 73
    • 0034998462 scopus 로고    scopus 로고
    • Allelic loss and gain, but not genomic instability, as the major somatic mutation in primary hepatocellular carcinoma
    • 11391792 10.1002/gcc.1138
    • Wang G, Zhao Y, Liu X, et al. Allelic loss and gain, but not genomic instability, as the major somatic mutation in primary hepatocellular carcinoma. Genes Chromosomes Cancer. 2001;31:221-227.
    • (2001) Genes Chromosomes Cancer , vol.31 , pp. 221-227
    • Wang, G.1    Zhao, Y.2    Liu, X.3
  • 74
    • 17544366381 scopus 로고    scopus 로고
    • Comprehensive allelotype study of hepatocellular carcinoma: Potential differences in pathways to hepatocellular carcinoma between hepatitis B virus-positive and -negative tumors
    • 10796882 10.1053/he.2000.6409 1:STN:280:DC%2BD3c3lsl2ktw%3D%3D
    • Okabe H, Ikai I, Matsuo K, et al. Comprehensive allelotype study of hepatocellular carcinoma: potential differences in pathways to hepatocellular carcinoma between hepatitis B virus-positive and -negative tumors. Hepatology. 2000;31:1073-1079.
    • (2000) Hepatology , vol.31 , pp. 1073-1079
    • Okabe, H.1    Ikai, I.2    Matsuo, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.