Comprehensive allelotype study of hepatocellular carcinoma: Potential differences in pathways to hepatocellular carcinoma between hepatitis B virus-positive and -negative tumors

Hepatology

Volumn 31, Issue 5, 2000, Pages 1073-1079

  Okabe, Hiroshi ^a   Ikai, Iwao ^a   Matsuo, Koichi ^a   Satoh, Seiji ^a   Momoi, Hirohito ^a   Kamikawa, Tatsuhiko ^a   Katsura, Nagato ^a   Nishitai, Ryuta ^a   Takeyama, Osamu ^a   Fukumoto, Manabu ^b   Yamaoka, Yoshio ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLELE; ARTICLE; CARCINOGENESIS; CHROMOSOME 13Q; CHROMOSOME 16Q; CHROMOSOME MAP; CLINICAL ARTICLE; DELETION MUTANT; FEMALE; HEPATITIS B VIRUS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER METASTASIS; MALE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; VIRUS GENOME;

EID: 17544366381     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/he.2000.6409     Document Type: Article

References (12)

1. Chen CJ, Yu MW, Liaw YE Epidemiological characteristics and risk factors of hepatocellular carcinoma. J Gastroenterol Hepatol 1997;12(Suppl):S294-308.
2. Miyakawa H, Izumi N, Marumo F, Sato C. Roles of alcohol, hepatitis virus infection, and gender in the development of hepatocellular carcinoma in patients with liver cirrhosis. Alcohol Clin Exp Res 1996;20(Suppl):91A-94A.
3. Goritsas CP, Athanasiadou A, Arvaniti A, Lampropoulou-Karatza C. The leading role of hepatitis B and C viruses as risk factors for the development of hepatocellular carcinoma. A case control study. J Clin Gastroenterol 1995;20:220-224.
4. Sakamoto M, Hirohashi S, Shimosato Y. Early stages of multistep hepatocarcinogenesis: adenomatous hyperplasia and early hepatocellular carcinoma. Hum Pathol 1991;22:172-178.
5. Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD. The Cell. 3rd edition. New York and London: Garland Publishing, 1994.
6. Shiratori Y, Shiina S, Zhang PY, Ohno E, Okudaira T, Payawal DA, Ono-Nita SK, et al. Does dual infection by hepatitis B and C viruses play an important role in the pathogenesis of hepatocellular carcinoma in Japan? Cancer 1997;80:2060-2067.
7. Matsuda Y, Amuro Y, Higashino K, Hada T, Yamamoto T, Fujikura M, Yamaguchi K, et al. Relation between markers for viral hepatitis and clinical features of Japanese patients with hepatocellular carcinoma: possible role of alcohol in promoting carcinogenesis. Hepatogastroenterology 1995;42:151-154.
8. Kim CM, Koike K, Saito I, Miyamura T, Jay G. HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 1991;351:317-320.
9. Moriya K, Fujie H, Shintani Y, Yotsuyanagi H, Tsutsumi T, Ishibashi K, Matsuura Y, et al. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med 1998;4:1065-1067.
10. Nishida N, Fukuda Y, Komeda T, Kita R, Sando T, Furukawa M, Amenomori M, et al. Amplification and overexpression of the cyclin Dl gene in aggressive human hepatocellular carcinoma. Cancer Res 1994;54:3107-3110.
11. Abou-Elella A, Gramlich T, Fritsch C, Gansler T. c-myc amplification in hepatocellular carcinoma predicts unfavorable prognosis. Mod Pathol 1996;9:95-98.
12. Nagai H, Pineau P, Tiollais P, Buendia MA, Dejean A. Comprehensive allelotyping of human hepatocellular carcinoma. Oncogene 1997;14:2927-2933.