-
1
-
-
84859366447
-
Protease signalling: the cutting edge
-
Turk B, Turk du SA, Turk V, (2012) Protease signalling: the cutting edge. EMBO Journal 31: 1630-1643.
-
(2012)
EMBO Journal
, vol.31
, pp. 1630-1643
-
-
Turk, B.1
du Turk, S.A.2
Turk, V.3
-
2
-
-
67649970990
-
Processing of peptide and hormone precursors at the dibasic cleavage sites
-
Rholam M, Fahy C, (2009) Processing of peptide and hormone precursors at the dibasic cleavage sites. Cellular and Molecular Life Sciences 66: 2075-2091.
-
(2009)
Cellular and Molecular Life Sciences
, vol.66
, pp. 2075-2091
-
-
Rholam, M.1
Fahy, C.2
-
3
-
-
0033452452
-
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides
-
Seidah NG, Chretien M, (1999) Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides. Brain Research 848: 45-62.
-
(1999)
Brain Research
, vol.848
, pp. 45-62
-
-
Seidah, N.G.1
Chretien, M.2
-
4
-
-
0025916877
-
Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway
-
Hosaka M, Nagahama M, Kim WS, Watanabe T, Hatsuzawa K, et al. (1991) Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway. Journal of Biological Chemistry 266: 12127-12130.
-
(1991)
Journal of Biological Chemistry
, vol.266
, pp. 12127-12130
-
-
Hosaka, M.1
Nagahama, M.2
Kim, W.S.3
Watanabe, T.4
Hatsuzawa, K.5
-
5
-
-
33746216577
-
The proprotein convertases and their implication in sterol and/or lipid metabolism
-
Seidah NG, Khatib AM, Prat A, (2006) The proprotein convertases and their implication in sterol and/or lipid metabolism. Biological Chemistry 387: 871-877.
-
(2006)
Biological Chemistry
, vol.387
, pp. 871-877
-
-
Seidah, N.G.1
Khatib, A.M.2
Prat, A.3
-
6
-
-
0030896832
-
Subtilases: the superfamily of subtilisin-like serine proteases
-
Siezen RJ, Leunissen JA, (1997) Subtilases: the superfamily of subtilisin-like serine proteases. Protein Science 6: 501-523.
-
(1997)
Protein Science
, vol.6
, pp. 501-523
-
-
Siezen, R.J.1
Leunissen, J.A.2
-
7
-
-
0027375104
-
Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis
-
Creemers JW, Siezen RJ, Roebroek AJ, Ayoubi TA, Huylebroeck D, et al. (1993) Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis. Journal of Biological Chemistry 268: 21826-21834.
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 21826-21834
-
-
Creemers, J.W.1
Siezen, R.J.2
Roebroek, A.J.3
Ayoubi, T.A.4
Huylebroeck, D.5
-
8
-
-
0028861480
-
Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum
-
Creemers JW, Vey M, Schafer W, Ayoubi TA, Roebroek AJ, et al. (1995) Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum. Journal of Biological Chemistry 270: 2695-2702.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 2695-2702
-
-
Creemers, J.W.1
Vey, M.2
Schafer, W.3
Ayoubi, T.A.4
Roebroek, A.J.5
-
9
-
-
29244460387
-
Lipopolysaccharide mediated regulation of neuroendocrine associated proprotein convertases and neuropeptide precursor processing in the rat spleen
-
Lansac G, Dong W, Dubois CM, Benlarbi N, Afonso C, et al. (2006) Lipopolysaccharide mediated regulation of neuroendocrine associated proprotein convertases and neuropeptide precursor processing in the rat spleen. Journal of Neuroimmunology 171: 57-71.
-
(2006)
Journal of Neuroimmunology
, vol.171
, pp. 57-71
-
-
Lansac, G.1
Dong, W.2
Dubois, C.M.3
Benlarbi, N.4
Afonso, C.5
-
10
-
-
0031028661
-
Expression of PC3, carboxypeptidase E and enkephalin in human monocyte-derived macrophages as a tool for genetic studies
-
LaMendola J, Martin SK, Steiner DF, (1997) Expression of PC3, carboxypeptidase E and enkephalin in human monocyte-derived macrophages as a tool for genetic studies. FEBS Letters 404: 19-22.
-
(1997)
FEBS Letters
, vol.404
, pp. 19-22
-
-
LaMendola, J.1
Martin, S.K.2
Steiner, D.F.3
-
11
-
-
0027962430
-
Prohormone convertases PC2 and PC3 in rat neutrophils and macrophages. Parallel changes with proenkephalin-derived peptides induced by LPS in vivo
-
Vindrola O, Mayer AM, Citera G, Spitzer JA, Espinoza LR, (1994) Prohormone convertases PC2 and PC3 in rat neutrophils and macrophages. Parallel changes with proenkephalin-derived peptides induced by LPS in vivo. Neuropeptides 27: 235-244.
-
(1994)
Neuropeptides
, vol.27
, pp. 235-244
-
-
Vindrola, O.1
Mayer, A.M.2
Citera, G.3
Spitzer, J.A.4
Espinoza, L.R.5
-
12
-
-
84860364695
-
Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion
-
Refaie S, Gagnon S, Gagnon H, Desjardins R, D'Anjou F, et al. (2012) Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion. Journal of Biological Chemistry 287: 14703-14717.
-
(2012)
Journal of Biological Chemistry
, vol.287
, pp. 14703-14717
-
-
Refaie, S.1
Gagnon, S.2
Gagnon, H.3
Desjardins, R.4
D'Anjou, F.5
-
13
-
-
43049179999
-
LPS/TLR4 signal transduction pathway
-
Lu YC, Yeh WC, Ohashi PS, (2008) LPS/TLR4 signal transduction pathway. Cytokine 42: 145-151.
-
(2008)
Cytokine
, vol.42
, pp. 145-151
-
-
Lu, Y.C.1
Yeh, W.C.2
Ohashi, P.S.3
-
14
-
-
0033574415
-
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
-
Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F, (1999) Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. Journal of Biological Chemistry 274: 10689-10692.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 10689-10692
-
-
Chow, J.C.1
Young, D.W.2
Golenbock, D.T.3
Christ, W.J.4
Gusovsky, F.5
-
15
-
-
42449119265
-
Fine tuning' TLR signaling
-
O'Neill LA, (2008) 'Fine tuning' TLR signaling. Nat Immunol 9: 459-461.
-
(2008)
Nat Immunol
, vol.9
, pp. 459-461
-
-
O'Neill, L.A.1
-
16
-
-
77950944395
-
Macrophages, innate immunity and cancer: balance, tolerance, and diversity
-
Mantovani A, Sica A, (2010) Macrophages, innate immunity and cancer: balance, tolerance, and diversity. Current Opinion in Immunology 22: 231-237.
-
(2010)
Current Opinion in Immunology
, vol.22
, pp. 231-237
-
-
Mantovani, A.1
Sica, A.2
-
17
-
-
0034643729
-
Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma
-
Gereda JE, Leung DY, Thatayatikom A, Streib JE, Price MR, et al. (2000) Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma. Lancet 355: 1680-1683.
-
(2000)
Lancet
, vol.355
, pp. 1680-1683
-
-
Gereda, J.E.1
Leung, D.Y.2
Thatayatikom, A.3
Streib, J.E.4
Price, M.R.5
-
18
-
-
33746356813
-
Human regulatory T cells and their role in autoimmune disease
-
Baecher-Allen C, Hafler D, (2006) Human regulatory T cells and their role in autoimmune disease. Immunological Reviews 212: 203-216.
-
(2006)
Immunological Reviews
, vol.212
, pp. 203-216
-
-
Baecher-Allen, C.1
Hafler, D.2
-
19
-
-
3142779901
-
Therapeutics targeting the innate immune system
-
Ulevitch RJ, (2004) Therapeutics targeting the innate immune system. Nat Rev Immunol 4: 512-520.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 512-520
-
-
Ulevitch, R.J.1
-
20
-
-
84863213361
-
Anticancer TLR agonists on the ropes
-
Guha M, (2012) Anticancer TLR agonists on the ropes. Nat Rev Drug Discov 11: 503-505.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 503-505
-
-
Guha, M.1
-
21
-
-
0027008354
-
The prohormone and proprotein processing enzymes PC1 and PC2: structure, selective cleavage of mouse POMC and human renin at pairs of basic residues, cellular expression, tissue distribution, and mRNA regulation
-
Seidah NG, Day R, Benjannet S, Rondeau N, Boudreault A, et al. (1992) The prohormone and proprotein processing enzymes PC1 and PC2: structure, selective cleavage of mouse POMC and human renin at pairs of basic residues, cellular expression, tissue distribution, and mRNA regulation. NIDA Research Monograph 126: 132-150.
-
(1992)
NIDA Research Monograph
, vol.126
, pp. 132-150
-
-
Seidah, N.G.1
Day, R.2
Benjannet, S.3
Rondeau, N.4
Boudreault, A.5
-
22
-
-
41149103075
-
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones
-
Hook V, Funkelstein L, Lu D, Bark S, Wegrzyn J, et al. (2008) Proteases for processing proneuropeptides into peptide neurotransmitters and hormones. Annual Review of Pharmacology and Toxicology 48: 393-423.
-
(2008)
Annual Review of Pharmacology and Toxicology
, vol.48
, pp. 393-423
-
-
Hook, V.1
Funkelstein, L.2
Lu, D.3
Bark, S.4
Wegrzyn, J.5
-
23
-
-
33750109567
-
Proprotein convertases: lessons from knockouts
-
Scamuffa N, Calvo F, Chretien M, Seidah NG, Khatib AM, (2006) Proprotein convertases: lessons from knockouts. FASEB Journal 20: 1954-1963.
-
(2006)
FASEB Journal
, vol.20
, pp. 1954-1963
-
-
Scamuffa, N.1
Calvo, F.2
Chretien, M.3
Seidah, N.G.4
Khatib, A.M.5
-
24
-
-
80955158570
-
Myeloid differentiation protein 2 silencing decreases LPS-induced cytokine production and TLR4/MyD88 pathway activity in alveolar macrophages
-
Ren W, Hu L, Hua F, Jin J, Wang Y, et al. (2011) Myeloid differentiation protein 2 silencing decreases LPS-induced cytokine production and TLR4/MyD88 pathway activity in alveolar macrophages. Immunology Letters 141: 94-101.
-
(2011)
Immunology Letters
, vol.141
, pp. 94-101
-
-
Ren, W.1
Hu, L.2
Hua, F.3
Jin, J.4
Wang, Y.5
-
25
-
-
0025803098
-
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2
-
Seidah NG, Marcinkiewicz M, Benjannet S, Gaspar L, Beaubien G, et al. (1991) Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2. Molecular Endocrinology 5: 111-122.
-
(1991)
Molecular Endocrinology
, vol.5
, pp. 111-122
-
-
Seidah, N.G.1
Marcinkiewicz, M.2
Benjannet, S.3
Gaspar, L.4
Beaubien, G.5
-
26
-
-
0027466131
-
Region specific expression of furin mRNA in the rat brain
-
Day R, Schafer MK, Cullinan WE, Watson SJ, Chretien M, et al. (1993) Region specific expression of furin mRNA in the rat brain. Neuroscience Letters 149: 27-30.
-
(1993)
Neuroscience Letters
, vol.149
, pp. 27-30
-
-
Day, R.1
Schafer, M.K.2
Cullinan, W.E.3
Watson, S.J.4
Chretien, M.5
-
27
-
-
0027965348
-
The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions
-
Seidah NG, Chretien M, Day R, (1994) The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions. Biochimie 76: 197-209.
-
(1994)
Biochimie
, vol.76
, pp. 197-209
-
-
Seidah, N.G.1
Chretien, M.2
Day, R.3
-
28
-
-
0034869540
-
Coexpression of proprotein convertase SPC3 and the neuroendocrine precursor proSAAS
-
Lanoue E, Day R, (2001) Coexpression of proprotein convertase SPC3 and the neuroendocrine precursor proSAAS. Endocrinology 142: 4141-4149.
-
(2001)
Endocrinology
, vol.142
, pp. 4141-4149
-
-
Lanoue, E.1
Day, R.2
-
29
-
-
0028943539
-
Distinct mRNA expression of the highly homologous convertases PC5 and PACE4 in the rat brain and pituitary
-
Dong W, Marcinkiewicz M, Vieau D, Chretien M, Seidah NG, et al. (1995) Distinct mRNA expression of the highly homologous convertases PC5 and PACE4 in the rat brain and pituitary. J Neurosci 15: 1778-1796.
-
(1995)
J Neurosci
, vol.15
, pp. 1778-1796
-
-
Dong, W.1
Marcinkiewicz, M.2
Vieau, D.3
Chretien, M.4
Seidah, N.G.5
-
30
-
-
0027274628
-
cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells
-
Lusson J, Vieau D, Hamelin J, Day R, Chretien M, et al. (1993) cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells. Proc Natl Acad Sci U S A 90: 6691-6695.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 6691-6695
-
-
Lusson, J.1
Vieau, D.2
Hamelin, J.3
Day, R.4
Chretien, M.5
-
31
-
-
0029916795
-
cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases
-
Seidah NG, Hamelin J, Mamarbachi M, Dong W, Tardos H, et al. (1996) cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. Proceedings of the National Academy of Sciences of the United States of America 93: 3388-3393.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, pp. 3388-3393
-
-
Seidah, N.G.1
Hamelin, J.2
Mamarbachi, M.3
Dong, W.4
Tardos, H.5
-
32
-
-
0024598765
-
A continuous alveolar macrophage cell line: comparisons with freshly derived alveolar macrophages
-
Helmke RJ, German VF, Mangos JA, (1989) A continuous alveolar macrophage cell line: comparisons with freshly derived alveolar macrophages. In Vitro Cell Dev Biol 25: 44-48.
-
(1989)
In Vitro Cell Dev Biol
, vol.25
, pp. 44-48
-
-
Helmke, R.J.1
German, V.F.2
Mangos, J.A.3
-
33
-
-
0023391094
-
From growth factor dependence to growth factor responsiveness: the genesis of an alveolar macrophage cell line
-
Helmke RJ, Boyd RL, German VF, Mangos JA, (1987) From growth factor dependence to growth factor responsiveness: the genesis of an alveolar macrophage cell line. In Vitro Cell Dev Biol 23: 567-574.
-
(1987)
In Vitro Cell Dev Biol
, vol.23
, pp. 567-574
-
-
Helmke, R.J.1
Boyd, R.L.2
German, V.F.3
Mangos, J.A.4
-
34
-
-
67649882495
-
Calnuc binds to LRP9 and affects its endosomal sorting
-
Brodeur J, Larkin H, Boucher R, Theriault C, St-Louis SC, et al. (2009) Calnuc binds to LRP9 and affects its endosomal sorting. Traffic 10: 1098-1114.
-
(2009)
Traffic
, vol.10
, pp. 1098-1114
-
-
Brodeur, J.1
Larkin, H.2
Boucher, R.3
Theriault, C.4
St-Louis, S.C.5
-
37
-
-
77953153778
-
Metadata matters: access to image data in the real world
-
Linkert M, Rueden CT, Allan C, Burel JM, Moore W, et al. (2010) Metadata matters: access to image data in the real world. J Cell Biol 189: 777-782.
-
(2010)
J Cell Biol
, vol.189
, pp. 777-782
-
-
Linkert, M.1
Rueden, C.T.2
Allan, C.3
Burel, J.M.4
Moore, W.5
-
38
-
-
0026609102
-
Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary
-
Day R, Schafer MK, Watson SJ, Chretien M, Seidah NG, (1992) Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary. Mol Endocrinol 6: 485-497.
-
(1992)
Mol Endocrinol
, vol.6
, pp. 485-497
-
-
Day, R.1
Schafer, M.K.2
Watson, S.J.3
Chretien, M.4
Seidah, N.G.5
-
39
-
-
79957909002
-
Molecular Validation of PACE4 as a Target in Prostate Cancer
-
D'Anjou F, Routhier S, Perreault JP, Latil A, Bonnel D, et al. (2011) Molecular Validation of PACE4 as a Target in Prostate Cancer. Transl Oncol 4: 157-172.
-
(2011)
Transl Oncol
, vol.4
, pp. 157-172
-
-
D'Anjou, F.1
Routhier, S.2
Perreault, J.P.3
Latil, A.4
Bonnel, D.5
-
40
-
-
70449720866
-
Subtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiation
-
Yuasa K, Masuda T, Yoshikawa C, Nagahama M, Matsuda Y, et al. (2009) Subtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiation. J Biochem 146: 407-415.
-
(2009)
J Biochem
, vol.146
, pp. 407-415
-
-
Yuasa, K.1
Masuda, T.2
Yoshikawa, C.3
Nagahama, M.4
Matsuda, Y.5
-
41
-
-
77952483341
-
Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats
-
Meng L, Zhu W, Jiang C, He X, Hou W, et al. (2010) Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats. Arthritis Res Ther 12: R103.
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Meng, L.1
Zhu, W.2
Jiang, C.3
He, X.4
Hou, W.5
-
42
-
-
0027368472
-
Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2
-
Benjannet S, Rondeau N, Paquet L, Boudreault A, Lazure C, et al. (1993) Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2. Biochemical Journal 294 (Pt 3): 735-743.
-
(1993)
Biochemical Journal
, vol.294
, Issue.Pt 3
, pp. 735-743
-
-
Benjannet, S.1
Rondeau, N.2
Paquet, L.3
Boudreault, A.4
Lazure, C.5
-
43
-
-
34547759249
-
PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism
-
Dikeakos JD, Mercure C, Lacombe MJ, Seidah NG, Reudelhuber TL, (2007) PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism. Febs J 274: 4094-4102.
-
(2007)
Febs J
, vol.274
, pp. 4094-4102
-
-
Dikeakos, J.D.1
Mercure, C.2
Lacombe, M.J.3
Seidah, N.G.4
Reudelhuber, T.L.5
-
44
-
-
0028238009
-
Evidence for cleavage of the PC1/PC3 pro-segment in the endoplasmic reticulum
-
Lindberg I, (1994) Evidence for cleavage of the PC1/PC3 pro-segment in the endoplasmic reticulum. Molecular and Cellular Neurosciences 5: 263-268.
-
(1994)
Molecular and Cellular Neurosciences
, vol.5
, pp. 263-268
-
-
Lindberg, I.1
-
45
-
-
9044241677
-
Primate homologues of rat TGN38: primary structure, expression and functional implications
-
Ponnambalam S, Girotti M, Yaspo ML, Owen CE, Perry AC, et al. (1996) Primate homologues of rat TGN38: primary structure, expression and functional implications. Journal of Cell Science 109 (Pt 3): 675-685.
-
(1996)
Journal of Cell Science
, vol.109
, Issue.Pt 3
, pp. 675-685
-
-
Ponnambalam, S.1
Girotti, M.2
Yaspo, M.L.3
Owen, C.E.4
Perry, A.C.5
-
46
-
-
0030889062
-
Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells
-
Prescott AR, Lucocq JM, James J, Lister JM, Ponnambalam S, (1997) Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells. European Journal of Cell Biology 72: 238-246.
-
(1997)
European Journal of Cell Biology
, vol.72
, pp. 238-246
-
-
Prescott, A.R.1
Lucocq, J.M.2
James, J.3
Lister, J.M.4
Ponnambalam, S.5
-
47
-
-
0033580299
-
The Rab5 effector EEA1 is a core component of endosome docking
-
Christoforidis S, McBride HM, Burgoyne RD, Zerial M, (1999) The Rab5 effector EEA1 is a core component of endosome docking. Nature 397: 621-625.
-
(1999)
Nature
, vol.397
, pp. 621-625
-
-
Christoforidis, S.1
McBride, H.M.2
Burgoyne, R.D.3
Zerial, M.4
-
48
-
-
0029030937
-
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
-
Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, et al. (1995) EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif. Journal of Biological Chemistry 270: 13503-13511.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 13503-13511
-
-
Mu, F.T.1
Callaghan, J.M.2
Steele-Mortimer, O.3
Stenmark, H.4
Parton, R.G.5
-
49
-
-
69249227502
-
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
-
Saftig P, Klumperman J, (2009) Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol 10: 623-635.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 623-635
-
-
Saftig, P.1
Klumperman, J.2
-
50
-
-
33846471307
-
LAMP proteins are required for fusion of lysosomes with phagosomes
-
Huynh KK, Eskelinen EL, Scott CC, Malevanets A, Saftig P, et al. (2007) LAMP proteins are required for fusion of lysosomes with phagosomes. EMBO Journal 26: 313-324.
-
(2007)
EMBO Journal
, vol.26
, pp. 313-324
-
-
Huynh, K.K.1
Eskelinen, E.L.2
Scott, C.C.3
Malevanets, A.4
Saftig, P.5
-
52
-
-
0029970951
-
The secretion of preformed granules by macrophages and neutrophils
-
Tapper H, (1996) The secretion of preformed granules by macrophages and neutrophils. Journal of Leukocyte Biology 59: 613-622.
-
(1996)
Journal of Leukocyte Biology
, vol.59
, pp. 613-622
-
-
Tapper, H.1
-
53
-
-
45349101571
-
Cytokine secretion requires phosphatidylcholine synthesis
-
Tian Y, Pate C, Andreolotti A, Wang L, Tuomanen E, et al. (2008) Cytokine secretion requires phosphatidylcholine synthesis. Journal of Cell Biology 181: 945-957.
-
(2008)
Journal of Cell Biology
, vol.181
, pp. 945-957
-
-
Tian, Y.1
Pate, C.2
Andreolotti, A.3
Wang, L.4
Tuomanen, E.5
-
54
-
-
0029850677
-
Rab11 regulates recycling through the pericentriolar recycling endosome
-
Ullrich O, Reinsch S, Urbe S, Zerial M, Parton RG, (1996) Rab11 regulates recycling through the pericentriolar recycling endosome. Journal of Cell Biology 135: 913-924.
-
(1996)
Journal of Cell Biology
, vol.135
, pp. 913-924
-
-
Ullrich, O.1
Reinsch, S.2
Urbe, S.3
Zerial, M.4
Parton, R.G.5
-
55
-
-
0031768460
-
Rab11 is required for trans-golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitor
-
Chen W, Feng Y, Chen D, Wandinger-Ness A, (1998) Rab11 is required for trans-golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitor. Molecular Biology of the Cell 9: 3241-3257.
-
(1998)
Molecular Biology of the Cell
, vol.9
, pp. 3241-3257
-
-
Chen, W.1
Feng, Y.2
Chen, D.3
Wandinger-Ness, A.4
-
56
-
-
0027398577
-
Rab9 functions in transport between late endosomes and the trans Golgi network
-
Lombardi D, Soldati T, Riederer MA, Goda Y, Zerial M, et al. (1993) Rab9 functions in transport between late endosomes and the trans Golgi network. EMBO Journal 12: 677-682.
-
(1993)
EMBO Journal
, vol.12
, pp. 677-682
-
-
Lombardi, D.1
Soldati, T.2
Riederer, M.A.3
Goda, Y.4
Zerial, M.5
-
57
-
-
0028224561
-
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network
-
Riederer MA, Soldati T, Shapiro AD, Lin J, Pfeffer SR, (1994) Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. Journal of Cell Biology 125: 573-582.
-
(1994)
Journal of Cell Biology
, vol.125
, pp. 573-582
-
-
Riederer, M.A.1
Soldati, T.2
Shapiro, A.D.3
Lin, J.4
Pfeffer, S.R.5
-
58
-
-
0026744303
-
The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
-
Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, et al. (1992) The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell 70: 715-728.
-
(1992)
Cell
, vol.70
, pp. 715-728
-
-
Bucci, C.1
Parton, R.G.2
Mather, I.H.3
Stunnenberg, H.4
Simons, K.5
-
59
-
-
0027182031
-
Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag
-
Chen YT, Holcomb C, Moore HP, (1993) Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag. Proceedings of the National Academy of Sciences of the United States of America 90: 6508-6512.
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, pp. 6508-6512
-
-
Chen, Y.T.1
Holcomb, C.2
Moore, H.P.3
-
60
-
-
48249101885
-
Rab8 regulates basolateral secretory, but not recycling, traffic at the recycling endosome
-
Henry L, Sheff DR, (2008) Rab8 regulates basolateral secretory, but not recycling, traffic at the recycling endosome. Molecular Biology of the Cell 19: 2059-2068.
-
(2008)
Molecular Biology of the Cell
, vol.19
, pp. 2059-2068
-
-
Henry, L.1
Sheff, D.R.2
-
61
-
-
0027517448
-
Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane
-
Huber LA, Pimplikar S, Parton RG, Virta H, Zerial M, et al. (1993) Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane. Journal of Cell Biology 123: 35-45.
-
(1993)
Journal of Cell Biology
, vol.123
, pp. 35-45
-
-
Huber, L.A.1
Pimplikar, S.2
Parton, R.G.3
Virta, H.4
Zerial, M.5
-
62
-
-
0029585762
-
Rab 7: an important regulator of late endocytic membrane traffic
-
Feng Y, Press B, Wandinger-Ness A, (1995) Rab 7: an important regulator of late endocytic membrane traffic. Journal of Cell Biology 131: 1435-1452.
-
(1995)
Journal of Cell Biology
, vol.131
, pp. 1435-1452
-
-
Feng, Y.1
Press, B.2
Wandinger-Ness, A.3
-
63
-
-
0028803110
-
The rab7 GTPase resides on a vesicular compartment connected to lysosomes
-
Meresse S, Gorvel JP, Chavrier P, (1995) The rab7 GTPase resides on a vesicular compartment connected to lysosomes. Journal of Cell Science 108 (Pt 11): 3349-3358.
-
(1995)
Journal of Cell Science
, vol.108
, Issue.Pt 11
, pp. 3349-3358
-
-
Meresse, S.1
Gorvel, J.P.2
Chavrier, P.3
-
64
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello CA, (1996) Biologic basis for interleukin-1 in disease. Blood 87: 2095-2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
65
-
-
0027336689
-
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
-
Hsieh CS, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, et al. (1993) Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 260: 547-549.
-
(1993)
Science
, vol.260
, pp. 547-549
-
-
Hsieh, C.S.1
Macatonia, S.E.2
Tripp, C.S.3
Wolf, S.F.4
O'Garra, A.5
-
66
-
-
0032765220
-
Natural killer cells in cross-regulation of IL-12 by IL-10 in Leishmania antigen-stimulated blood donor cells
-
Akuffo H, Alexis A, Eidsmo L, Saed A, Nylen S, et al. (1999) Natural killer cells in cross-regulation of IL-12 by IL-10 in Leishmania antigen-stimulated blood donor cells. Clinical and Experimental Immunology 117: 529-534.
-
(1999)
Clinical and Experimental Immunology
, vol.117
, pp. 529-534
-
-
Akuffo, H.1
Alexis, A.2
Eidsmo, L.3
Saed, A.4
Nylen, S.5
-
67
-
-
0026088633
-
Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans
-
Smeekens SP, Avruch AS, LaMendola J, Chan SJ, Steiner DF, (1991) Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans. Proc Natl Acad Sci U S A 88: 340-344.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 340-344
-
-
Smeekens, S.P.1
Avruch, A.S.2
LaMendola, J.3
Chan, S.J.4
Steiner, D.F.5
-
68
-
-
0030949271
-
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
-
Jackson RS, Creemers JW, Ohagi S, Raffin-Sanson ML, Sanders L, et al. (1997) Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Nature Genetics 16: 303-306.
-
(1997)
Nature Genetics
, vol.16
, pp. 303-306
-
-
Jackson, R.S.1
Creemers, J.W.2
Ohagi, S.3
Raffin-Sanson, M.L.4
Sanders, L.5
-
69
-
-
0036679173
-
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
-
Zhu X, Zhou A, Dey A, Norrbom C, Carroll R, et al. (2002) Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. Proceedings of the National Academy of Sciences of the United States of America 99: 10293-10298.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, pp. 10293-10298
-
-
Zhu, X.1
Zhou, A.2
Dey, A.3
Norrbom, C.4
Carroll, R.5
-
70
-
-
0031728020
-
Differential response to a stress stimulus of proenkephalin peptide content in immune cells of naive and chronically stressed rats
-
Saravia F, Padros MR, Ase A, Aloyz R, Duran S, et al. (1998) Differential response to a stress stimulus of proenkephalin peptide content in immune cells of naive and chronically stressed rats. Neuropeptides 32: 351-359.
-
(1998)
Neuropeptides
, vol.32
, pp. 351-359
-
-
Saravia, F.1
Padros, M.R.2
Ase, A.3
Aloyz, R.4
Duran, S.5
-
71
-
-
0035980127
-
Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1
-
Basak A, Koch P, Dupelle M, Fricker LD, Devi LA, et al. (2001) Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1. J Biol Chem 276: 32720-32728.
-
(2001)
J Biol Chem
, vol.276
, pp. 32720-32728
-
-
Basak, A.1
Koch, P.2
Dupelle, M.3
Fricker, L.D.4
Devi, L.A.5
-
72
-
-
4444279559
-
Prohormone convertase 1 (PC1) processing and sorting: effect of PC1 propeptide and proSAAS
-
Lee SN, Prodhomme E, Lindberg I, (2004) Prohormone convertase 1 (PC1) processing and sorting: effect of PC1 propeptide and proSAAS. J Endocrinol 182: 353-364.
-
(2004)
J Endocrinol
, vol.182
, pp. 353-364
-
-
Lee, S.N.1
Prodhomme, E.2
Lindberg, I.3
-
73
-
-
0017762129
-
Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS
-
Ralph P, Nakoinz I, (1977) Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS. Journal of Immunology 119: 950-954.
-
(1977)
Journal of Immunology
, vol.119
, pp. 950-954
-
-
Ralph, P.1
Nakoinz, I.2
-
74
-
-
0027365466
-
Immunocytochemical localization of the neuropeptide-synthesizing enzyme PC1 in AtT-20 cells
-
Hornby PJ, Rosenthal SD, Mathis JP, Vindrola O, Lindberg I, (1993) Immunocytochemical localization of the neuropeptide-synthesizing enzyme PC1 in AtT-20 cells. Neuroendocrinology 58: 555-563.
-
(1993)
Neuroendocrinology
, vol.58
, pp. 555-563
-
-
Hornby, P.J.1
Rosenthal, S.D.2
Mathis, J.P.3
Vindrola, O.4
Lindberg, I.5
-
75
-
-
0028855242
-
Electron microscopic immunocytochemical evidence for the involvement of the convertases PC1 and PC2 in the processing of proinsulin in pancreatic beta-cells
-
Malide D, Seidah NG, Chretien M, Bendayan M, (1995) Electron microscopic immunocytochemical evidence for the involvement of the convertases PC1 and PC2 in the processing of proinsulin in pancreatic beta-cells. Journal of Histochemistry and Cytochemistry 43: 11-19.
-
(1995)
Journal of Histochemistry and Cytochemistry
, vol.43
, pp. 11-19
-
-
Malide, D.1
Seidah, N.G.2
Chretien, M.3
Bendayan, M.4
-
76
-
-
0026693483
-
A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase
-
Bailyes EM, Shennan KI, Seal AJ, Smeekens SP, Steiner DF, et al. (1992) A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase. Biochem J 285 (Pt 2): 391-394.
-
(1992)
Biochem J
, vol.285
, Issue.Pt 2
, pp. 391-394
-
-
Bailyes, E.M.1
Shennan, K.I.2
Seal, A.J.3
Smeekens, S.P.4
Steiner, D.F.5
-
77
-
-
0029776389
-
Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets
-
Tanaka S, Kurabuchi S, Mochida H, Kato T, Takahashi S, et al. (1996) Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets. Archives of Histology and Cytology 59: 261-271.
-
(1996)
Archives of Histology and Cytology
, vol.59
, pp. 261-271
-
-
Tanaka, S.1
Kurabuchi, S.2
Mochida, H.3
Kato, T.4
Takahashi, S.5
-
78
-
-
79955466520
-
Mechanisms of cytokine secretion: a portfolio of distinct pathways allows flexibility in cytokine activity
-
Duitman EH, Orinska Z, Bulfone-Paus S, (2011) Mechanisms of cytokine secretion: a portfolio of distinct pathways allows flexibility in cytokine activity. European Journal of Cell Biology 90: 476-483.
-
(2011)
European Journal of Cell Biology
, vol.90
, pp. 476-483
-
-
Duitman, E.H.1
Orinska, Z.2
Bulfone-Paus, S.3
-
79
-
-
68349117545
-
Cytokine secretion in macrophages and other cells: pathways and mediators
-
Stow JL, Low PC, Offenhauser C, Sangermani D, (2009) Cytokine secretion in macrophages and other cells: pathways and mediators. Immunobiology 214: 601-612.
-
(2009)
Immunobiology
, vol.214
, pp. 601-612
-
-
Stow, J.L.1
Low, P.C.2
Offenhauser, C.3
Sangermani, D.4
-
80
-
-
0026408814
-
Role of enzyme receptors and inhibitors in regulating proteolytic activities of macrophages
-
Chapman HA Jr, (1991) Role of enzyme receptors and inhibitors in regulating proteolytic activities of macrophages. Annals of the New York Academy of Sciences 624: 87-96.
-
(1991)
Annals of the New York Academy of Sciences
, vol.624
, pp. 87-96
-
-
Chapman Jr., H.A.1
-
81
-
-
80052679918
-
N-glycosylation controls trafficking, zymogen activation and substrate processing of proprotein convertases PC1/3 and subtilisin kexin isozyme-1
-
Zandberg WF, Benjannet S, Hamelin J, Pinto BM, Seidah NG, (2011) N-glycosylation controls trafficking, zymogen activation and substrate processing of proprotein convertases PC1/3 and subtilisin kexin isozyme-1. Glycobiology 21: 1290-1300.
-
(2011)
Glycobiology
, vol.21
, pp. 1290-1300
-
-
Zandberg, W.F.1
Benjannet, S.2
Hamelin, J.3
Pinto, B.M.4
Seidah, N.G.5
-
82
-
-
55249109400
-
Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens
-
Zhao Z, Fux B, Goodwin M, Dunay IR, Strong D, et al. (2008) Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host Microbe 4: 458-469.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 458-469
-
-
Zhao, Z.1
Fux, B.2
Goodwin, M.3
Dunay, I.R.4
Strong, D.5
-
83
-
-
0032695622
-
Phagocytosis of microorganisms by means of overshooting pseudopods: where do we stand?
-
Rittig MG, Wilske B, Krause A, (1999) Phagocytosis of microorganisms by means of overshooting pseudopods: where do we stand? Microbes Infect 1: 727-735.
-
(1999)
Microbes Infect
, vol.1
, pp. 727-735
-
-
Rittig, M.G.1
Wilske, B.2
Krause, A.3
-
84
-
-
0028337442
-
Enzymatic properties of carboxyl-terminally truncated prohormone convertase 1 (PC1/SPC3) and evidence for autocatalytic conversion
-
Zhou Y, Lindberg I, (1994) Enzymatic properties of carboxyl-terminally truncated prohormone convertase 1 (PC1/SPC3) and evidence for autocatalytic conversion. Journal of Biological Chemistry 269: 18408-18413.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 18408-18413
-
-
Zhou, Y.1
Lindberg, I.2
-
85
-
-
0025265421
-
Plasticity of the tubular lysosomal compartment in macrophages
-
Knapp PE, Swanson JA, (1990) Plasticity of the tubular lysosomal compartment in macrophages. Journal of Cell Science 95 (Pt 3): 433-439.
-
(1990)
Journal of Cell Science
, vol.95
, Issue.Pt 3
, pp. 433-439
-
-
Knapp, P.E.1
Swanson, J.A.2
-
86
-
-
0038316341
-
ER-mediated phagocytosis: a new membrane for new functions
-
Desjardins M, (2003) ER-mediated phagocytosis: a new membrane for new functions. Nat Rev Immunol 3: 280-291.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 280-291
-
-
Desjardins, M.1
-
87
-
-
0021334520
-
Immunoreactive beta-endorphin in a subpopulation of mouse spleen macrophages
-
Lolait SJ, Lim AT, Toh BH, Funder JW, (1984) Immunoreactive beta-endorphin in a subpopulation of mouse spleen macrophages. J Clin Invest 73: 277-280.
-
(1984)
J Clin Invest
, vol.73
, pp. 277-280
-
-
Lolait, S.J.1
Lim, A.T.2
Toh, B.H.3
Funder, J.W.4
-
88
-
-
0041802728
-
Expression of somatostatin, cortistatin, and somatostatin receptors in human monocytes, macrophages, and dendritic cells
-
Dalm VA, van Hagen PM, van Koetsveld PM, Achilefu S, Houtsmuller AB, et al. (2003) Expression of somatostatin, cortistatin, and somatostatin receptors in human monocytes, macrophages, and dendritic cells. Am J Physiol Endocrinol Metab 285: E344-353.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Dalm, V.A.1
van Hagen, P.M.2
van Koetsveld, P.M.3
Achilefu, S.4
Houtsmuller, A.B.5
-
89
-
-
28544452195
-
A role for the phagosome in cytokine secretion
-
Murray RZ, Kay JG, Sangermani DG, Stow JL, (2005) A role for the phagosome in cytokine secretion. Science 310: 1492-1495.
-
(2005)
Science
, vol.310
, pp. 1492-1495
-
-
Murray, R.Z.1
Kay, J.G.2
Sangermani, D.G.3
Stow, J.L.4
-
90
-
-
84859707022
-
Signaling at neuro/immune synapses
-
Dustin ML, (2012) Signaling at neuro/immune synapses. Journal of Clinical Investigation 122: 1149-1155.
-
(2012)
Journal of Clinical Investigation
, vol.122
, pp. 1149-1155
-
-
Dustin, M.L.1
-
91
-
-
0035794132
-
The role of dibasic residues in prohormone sorting to the regulated secretory pathway. A study with proneurotensin
-
Feliciangeli S, Kitabgi P, Bidard JN, (2001) The role of dibasic residues in prohormone sorting to the regulated secretory pathway. A study with proneurotensin. Journal of Biological Chemistry 276: 6140-6150.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 6140-6150
-
-
Feliciangeli, S.1
Kitabgi, P.2
Bidard, J.N.3
-
92
-
-
0029787008
-
A protease processing site is essential for prorenin sorting to the regulated secretory pathway
-
Brechler V, Chu WN, Baxter JD, Thibault G, Reudelhuber TL, (1996) A protease processing site is essential for prorenin sorting to the regulated secretory pathway. Journal of Biological Chemistry 271: 20636-20640.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 20636-20640
-
-
Brechler, V.1
Chu, W.N.2
Baxter, J.D.3
Thibault, G.4
Reudelhuber, T.L.5
-
93
-
-
1242272053
-
Progastrin is directed to the regulated secretory pathway by synergistically acting basic and acidic motifs
-
Bundgaard JR, Birkedal H, Rehfeld JF, (2004) Progastrin is directed to the regulated secretory pathway by synergistically acting basic and acidic motifs. Journal of Biological Chemistry 279: 5488-5493.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 5488-5493
-
-
Bundgaard, J.R.1
Birkedal, H.2
Rehfeld, J.F.3
-
94
-
-
15444366205
-
Neuropeptide processing profile in mice lacking prohormone convertase-1
-
Pan H, Nanno D, Che FY, Zhu X, Salton SR, et al. (2005) Neuropeptide processing profile in mice lacking prohormone convertase-1. Biochemistry 44: 4939-4948.
-
(2005)
Biochemistry
, vol.44
, pp. 4939-4948
-
-
Pan, H.1
Nanno, D.2
Che, F.Y.3
Zhu, X.4
Salton, S.R.5
|