A High Throughput Screen for RGS Proteins Using Steady State Monitoring of Free Phosphate Formation

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Monroy, C Aaron ^a   Mackie, Duncan I ^a   Roman, David L ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CELASTROL; G PROTEIN COUPLED RECEPTOR; GAMBOGIC ACID; GLUTATHIONE TRANSFERASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MALACHITE GREEN; PHOSPHATE; RECOMBINANT PROTEIN; RGS PROTEIN; RGS17 PROTEIN; RGS4 PROTEIN; RGS8 PROTEIN; SANGUINARINE; UI 1593; UI 1907; UI 2034; UI 5; UNCLASSIFIED DRUG; FUCHSINE; MOLECULAR LIBRARY;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RAT; SIGNAL TRANSDUCTION; STEADY STATE; ANIMAL; DIAGNOSTIC USE; DRUG EFFECTS; ENZYME ACTIVATION; HYDROLYSIS; METABOLISM; MOLECULAR LIBRARY;

ANIMALS; ENZYME ACTIVATION; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; HYDROLYSIS; PHOSPHATES; RATS; RGS PROTEINS; ROSANILINE DYES; SMALL MOLECULE LIBRARIES;

EID: 84876575524     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062247     Document Type: Article

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