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Volumn 9, Issue 3, 2013, Pages 499-510

Encapsulation of trans-dehydrocrotonin in liposomes: An enhancement of the antitumor activity

Author keywords

Antitumor Activity; Cyclodextrin; Kinetics; Liposomes; Trans Dehydrocrotonin

Indexed keywords

ANTI-TUMOR ACTIVITIES; ENCAPSULATION EFFICIENCY; INCLUSION COMPLEX; KINETIC PROFILES; LIPOSOMAL FORMULATION; PHOSPHOLIPID BILAYER; TRANS-DEHYDROCROTONIN; TUMOR INHIBITION;

EID: 84876570534     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1554     Document Type: Article
Times cited : (26)

References (41)
  • 2
    • 0032760637 scopus 로고    scopus 로고
    • Anti-tumor activity of two 19-nor-clerodane diterpenes, trans-dehydrocrotonin and transcrotonin, from Croton cajucara
    • N. F. Grynberg, A. Echevarria, J. E. Lima, S. S. R. Pamplona, A. C. Pinto, and M. A. M. Maciel, Anti-tumor activity of two 19-nor-clerodane diterpenes, trans-dehydrocrotonin and transcrotonin, from Croton cajucara. Planta Med. 65, 687 (1999).
    • (1999) Planta Med. , vol.65 , pp. 687
    • Grynberg, N.F.1    Echevarria, A.2    Lima, J.E.3    Pamplona, S.S.R.4    Pinto, A.C.5    MacIel, M.A.M.6
  • 3
    • 1642315349 scopus 로고    scopus 로고
    • Natural killer cell activity and anti-tumour effects of dehydrocrotonin and its synthetic derivatives
    • P. S. Melo, G. Z. Justo, N. Durán, and M. Haun, Natural killer cell activity and anti-tumour effects of dehydrocrotonin and its synthetic derivatives. Eur. J. Pharmacol. 487, 47 (2004).
    • (2004) Eur. J. Pharmacol. , vol.487 , pp. 47
    • Melo, P.S.1    Justo, G.Z.2    Durán, N.3    Haun, M.4
  • 4
    • 0035666449 scopus 로고    scopus 로고
    • Blood glucose- and triglyceride-lowering effect of transdehydrocrotonin, a diterpene from Croton cajucara Benth in rats
    • R. M. Silva, F. A. Santos, V. S. N. Rao, M. A. M. Maciel, and A. C. Pinto, Blood glucose- and triglyceride-lowering effect of transdehydrocrotonin, a diterpene from Croton cajucara Benth in rats. Diab. Obes. Metab. 3, 452 (2001).
    • (2001) Diab. Obes. Metab. , vol.3 , pp. 452
    • Silva, R.M.1    Santos, F.A.2    Rao, V.S.N.3    MacIel, M.A.M.4    Pinto, A.C.5
  • 5
    • 4544273401 scopus 로고    scopus 로고
    • Chronic treatment with bark infusion from Croton cajucara lowers plasma triglyceride levels in genetic hyperlipidemic mice
    • E. J. B. Bighetti, A. R. M. Souza-Brito, E. C. De Faria, and H. C. F. Oliveira, Chronic treatment with bark infusion from Croton cajucara lowers plasma triglyceride levels in genetic hyperlipidemic mice. Can. J. Physiol. Pharmacol. 82, 387 (2004).
    • (2004) Can. J. Physiol. Pharmacol. , vol.82 , pp. 387
    • Bighetti, E.J.B.1    Souza-Brito, A.R.M.2    De Faria, E.C.3    Oliveira, H.C.F.4
  • 6
    • 0035038281 scopus 로고    scopus 로고
    • The lipid-lowering effect of trans-dehydrocrotonin, a clerodane diterpene from Croton cajucara Benth in mice fed on high-fat diet
    • R. M. Silva, F. A. Santos, V. S. N. Rao, M. A. M. Maciel, and A. C. Pinto, The lipid-lowering effect of trans-dehydrocrotonin, a clerodane diterpene from Croton cajucara Benth in mice fed on high-fat diet. J. Pharm. Pharmacol. 53, 535 (2001).
    • (2001) J. Pharm. Pharmacol. , vol.53 , pp. 535
    • Silva, R.M.1    Santos, F.A.2    Rao, V.S.N.3    MacIel, M.A.M.4    Pinto, A.C.5
  • 7
    • 0035671970 scopus 로고    scopus 로고
    • Antigenotoxicity of trans-dehydrocrotonin, a clerodane diterpene from Croton cajucara
    • A. R. Agner, M. A. M. Maciel, A. C. Pinto, and I. M. S. Cólus, Antigenotoxicity of trans-dehydrocrotonin, a clerodane diterpene from Croton cajucara. Planta Med. 67, 815 (2001).
    • (2001) Planta Med. , vol.67 , pp. 815
    • Agner, A.R.1    MacIel, M.A.M.2    Pinto, A.C.3    Cólus, I.M.S.4
  • 8
    • 4844231623 scopus 로고    scopus 로고
    • Antiulcer activity and subacute toxicity of trans-dehydrocrotonin from Croton cajucara
    • J. A. Rodríguez, C. A. Hiruma-Lima, and A. R. M. Souza-Brito, Antiulcer activity and subacute toxicity of trans-dehydrocrotonin from Croton cajucara. Hum. Exp. Toxicol. 23, 455 (2004).
    • (2004) Hum. Exp. Toxicol. , vol.23 , pp. 455
    • Rodríguez, J.A.1    Hiruma-Lima, C.A.2    Souza-Brito, A.R.M.3
  • 9
    • 0000833568 scopus 로고    scopus 로고
    • Investigation of anti-inflammatory and antinociceptive activities of transdehydrocrotonin, a 19-nor-clerodane diterpene from Croton cajucara, Part 1
    • J. C. T. Carvalho, M. F. C. Silva, M. A. M. Maciel, A. C. Pinto, D. S. Nunes, R. M. Lima, J. K. Bastos, and S. J. Sarti, Investigation of anti-inflammatory and antinociceptive activities of transdehydrocrotonin, a 19-nor-clerodane diterpene from Croton cajucara, Part 1. Planta Med. 62, 402 (1996).
    • (1996) Planta Med. , vol.62 , pp. 402
    • Carvalho, J.C.T.1    Silva, M.F.C.2    MacIel, M.A.M.3    Pinto, A.C.4    Nunes, D.S.5    Lima, R.M.6    Bastos, J.K.7    Sarti, S.J.8
  • 10
    • 0032796882 scopus 로고    scopus 로고
    • Antioestrogenic effect of transdehydrocrotonin, a nor-clerodane diterpene from Croton cajucara Benth in rats
    • A. M. Luna-Costa, J. C. R. Sila, A. R. Campos, V. S. N. Rao, M. A. M. Maciel, and A. C. Pinto, Antioestrogenic effect of transdehydrocrotonin, a nor-clerodane diterpene from Croton cajucara Benth in rats. Phytother. Res. 13, 689 (1999).
    • (1999) Phytother. Res. , vol.13 , pp. 689
    • Luna-Costa, A.M.1    Sila, J.C.R.2    Campos, A.R.3    Rao, V.S.N.4    MacIel, M.A.M.5    Pinto, A.C.6
  • 12
    • 0038060679 scopus 로고    scopus 로고
    • Comparative cytotoxicity of dimethylamide-crotonin in the promyelocytic leukemia cell line (HL60) and human peripheral blood mononuclear cells
    • M. C. Anazetti, P. S. Melo, N. Durán, and M. Haun, Comparative cytotoxicity of dimethylamide-crotonin in the promyelocytic leukemia cell line (HL60) and human peripheral blood mononuclear cells. Toxicol. 188, 261 (2003).
    • (2003) Toxicol. , vol.188 , pp. 261
    • Anazetti, M.C.1    Melo, P.S.2    Durán, N.3    Haun, M.4
  • 13
    • 4444261752 scopus 로고    scopus 로고
    • Dehydrocrotonin and its derivative dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2 -6 and -9 in human leukemic cells HL60
    • M. C. Anazetti, P. S. Melo, N. Durán, and M. Haun, Dehydrocrotonin and its derivative dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells HL60. Toxicol. 203, 123 (2004).
    • (2004) Toxicol. , vol.203 , pp. 123
    • Anazetti, M.C.1    Melo, P.S.2    Durán, N.3    Haun, M.4
  • 14
    • 14644442878 scopus 로고    scopus 로고
    • Dehydrocrotonin and its betacyclodextrin complex: Cytotoxicity in V79 fibroblasts and rat cultured hepatocytes
    • D. H. A. Corrêa, P. S. Melo, C. A. A. De Carvallho, M. B. M. De Azevedo, N. Durán, and M. Haun, Dehydrocrotonin and its betacyclodextrin complex: Cytotoxicity in V79 fibroblasts and rat cultured hepatocytes. Eur. J. Pharmacol. 510, 17 (2005).
    • (2005) Eur. J. Pharmacol. , vol.510 , pp. 17
    • Corrêa, D.H.A.1    Melo, P.S.2    De Carvallho, C.A.A.3    De Azevedo, M.B.M.4    Durán, N.5    Haun, M.6
  • 16
    • 0035961446 scopus 로고    scopus 로고
    • Cytotoxicity of derivatives from dehydrocrotonin on V79 cells and Escherichia coli
    • P. S. Melo, N. Duran, and M. Haun, Cytotoxicity of derivatives from dehydrocrotonin on V79 cells and Escherichia coli. Toxicology 159, 135 (2001).
    • (2001) Toxicology , vol.159 , pp. 135
    • Melo, P.S.1    Duran, N.2    Haun, M.3
  • 17
    • 0032813190 scopus 로고    scopus 로고
    • Cytotoxicity of trans-dehydrocrotonin from Croton cajucara on V79 Cells and rat hepatocytes
    • J. A. Rodríguez and M. Haun, Cytotoxicity of trans-dehydrocrotonin from Croton cajucara on V79 Cells and rat hepatocytes. Planta Med. 65, 522 (1999).
    • (1999) Planta Med. , vol.65 , pp. 522
    • Rodríguez, J.A.1    Haun, M.2
  • 18
    • 54949136864 scopus 로고    scopus 로고
    • Exploring the use of novel drug delivery systems for antiretroviral drugs
    • E. Ojewole, I. Mackraj, P. Naidoo, and T. Govender, Exploring the use of novel drug delivery systems for antiretroviral drugs. Eur. J. Pharm. Biopharm. 70, 697 (2008).
    • (2008) Eur. J. Pharm. Biopharm. , vol.70 , pp. 697
    • Ojewole, E.1    MacKraj, I.2    Naidoo, P.3    Govender, T.4
  • 19
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carrier
    • V. P. Torchilin, Recent advances with liposomes as pharmaceutical carrier. Nature Rev. Drug Disc. 4, 145 (2005).
    • (2005) Nature Rev. Drug Disc. , vol.4 , pp. 145
    • Torchilin, V.P.1
  • 20
    • 31344478508 scopus 로고    scopus 로고
    • Liposomes in analyses
    • K. A. Edwards and A. J. Baeumner, Liposomes in analyses. Talanta 68, 1432 (2006).
    • (2006) Talanta , vol.68 , pp. 1432
    • Edwards, K.A.1    Baeumner, A.J.2
  • 22
    • 34548134519 scopus 로고    scopus 로고
    • Cyclodextrins as pharmaceutical solubilizers
    • M. E. Brewster and T. Loftsson, Cyclodextrins as pharmaceutical solubilizers. Adv. Drug Del. Rev. 59, 645 (2007).
    • (2007) Adv. Drug Del. Rev. , vol.59 , pp. 645
    • Brewster, M.E.1    Loftsson, T.2
  • 23
    • 33645020487 scopus 로고    scopus 로고
    • Betamethasone-in-cyclodextrin-in-liposome: The effect of cyclodextrins on encapsulation efficiency and release kinetics
    • G. Piel, M. Piette, V. Barillaro, D. Castagne, B. Evrard, and L. Delattre, Betamethasone-in-cyclodextrin-in-liposome: The effect of cyclodextrins on encapsulation efficiency and release kinetics. Int. J. Pharm. 312, 75 (2006).
    • (2006) Int. J. Pharm. , vol.312 , pp. 75
    • Piel, G.1    Piette, M.2    Barillaro, V.3    Castagne, D.4    Evrard, B.5    Delattre, L.6
  • 24
    • 33847105481 scopus 로고    scopus 로고
    • Integrity of liposomes in presence of cyclodextrins: Effect of liposome type and lipid composition
    • P. Hatzi, S. Mourtas, P. G. Klepetsanis, and S. G. Antimisiaris, Integrity of liposomes in presence of cyclodextrins: Effect of liposome type and lipid composition. Int. J. Pharm. 333, 167 (2007).
    • (2007) Int. J. Pharm. , vol.333 , pp. 167
    • Hatzi, P.1    Mourtas, S.2    Klepetsanis, P.G.3    Antimisiaris, S.G.4
  • 27
    • 84860183024 scopus 로고    scopus 로고
    • Aspect of natural products on the discovery of new antitumoral and antimutagenic agents
    • M. A. M. Maciel, R. S. Leal, T. N. C. Dantas, and V. F. Veiga, Jr, Aspect of natural products on the discovery of new antitumoral and antimutagenic agents. Rev. Fitos 3, 37 (2007).
    • (2007) Rev. Fitos , vol.3 , pp. 37
    • MacIel, M.A.M.1    Leal, R.S.2    Dantas, T.N.C.3    Veiga Jr., V.F.4
  • 28
    • 0037242745 scopus 로고    scopus 로고
    • NMR and structure review of some natural fluroclerodanes
    • M. A. M. Maciel, A. C. Pinto, and C. R. Kaiser, NMR and structure review of some natural fluroclerodanes. Magn. Reson. Chem. 41, 278 (2003).
    • (2003) Magn. Reson. Chem. , vol.41 , pp. 278
    • MacIel, M.A.M.1    Pinto, A.C.2    Kaiser, C.R.3
  • 29
    • 84860163830 scopus 로고    scopus 로고
    • Validation of a UV spectrophotometric method for determining trans-dehydrocrotonin in inclusion complexes with hydroxypropyl-β- cyclodextrin
    • T. L. S. Lapenda, W. A. Morais, M. C. B. Lira, M. A. M. Maciel, N. S. Santos-Magalhães, Validation of a UV spectrophotometric method for determining trans-dehydrocrotonin in inclusion complexes with hydroxypropyl-β-cyclodextrin. Lat. Am. J. Pharm. 31, 97 (2012).
    • (2012) Lat. Am. J. Pharm. , vol.31 , pp. 97
    • Lapenda, T.L.S.1    Morais, W.A.2    Lira, M.C.B.3    MacIel, M.A.M.4    Santos- Magalhães, N.S.5
  • 31
    • 40949133332 scopus 로고    scopus 로고
    • PLGA-based drug delivery systems: Importance of the type of drug and device geometry
    • D. Klose, F. Siepmann, K. Elkharraz, and J. Siepmann, PLGA-based drug delivery systems: Importance of the type of drug and device geometry. Int. J. Pharm. 354, 95 (2008).
    • (2008) Int. J. Pharm. , vol.354 , pp. 95
    • Klose, D.1    Siepmann, F.2    Elkharraz, K.3    Siepmann, J.4
  • 32
    • 55849092853 scopus 로고    scopus 로고
    • Mathematical modeling of drug delivery
    • J. Siepmann and F. Siepmann, Mathematical modeling of drug delivery. Int. J. Pharm. 364, 328 (2008).
    • (2008) Int. J. Pharm. , vol.364 , pp. 328
    • Siepmann, J.1    Siepmann, F.2
  • 35
    • 33748796936 scopus 로고    scopus 로고
    • Lyophilisation and sterilisation of liposomal vaccines to produce stable and sterile products
    • A. R. Mohammed, V. W. Bramwell, A. G. A. Coombes, and Y. Perrie, Lyophilisation and sterilisation of liposomal vaccines to produce stable and sterile products. Methods 40, 30 (2006).
    • (2006) Methods , vol.40 , pp. 30
    • Mohammed, A.R.1    Bramwell, V.W.2    Coombes, A.G.A.3    Perrie, Y.4
  • 36
    • 34547800192 scopus 로고    scopus 로고
    • Freezedrying of nanoparticles: Formulation, process and storage considerations
    • W. Abdelwahed, G. Degobert, S. Stainmesse, and H. Fessi, Freezedrying of nanoparticles: Formulation, process and storage considerations. Adv. Drug Deliv. 58, 1688 (2006).
    • (2006) Adv. Drug Deliv. , vol.58 , pp. 1688
    • Abdelwahed, W.1    Degobert, G.2    Stainmesse, S.3    Fessi, H.4
  • 37
    • 68549092406 scopus 로고    scopus 로고
    • The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator
    • J. Y. Kim, J. K. Kim, J. S. Park, Y. Byun, and C. K. Kim, The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator. Biomaterials 30, 5751 (2009).
    • (2009) Biomaterials , vol.30 , pp. 5751
    • Kim, J.Y.1    Kim, J.K.2    Park, J.S.3    Byun, Y.4    Kim, C.K.5
  • 38
    • 0029940928 scopus 로고    scopus 로고
    • Evaluation of cationic polymer-coated nanocapsules as ocular drug carries
    • P. Calvo, J. L. Vila-Jato, and M. J. Alonso, Evaluation of cationic polymer-coated nanocapsules as ocular drug carries. J. Pharm. Sci. 85, 530 (1996).
    • (1996) J. Pharm. Sci. , vol.85 , pp. 530
    • Calvo, P.1    Vila-Jato, J.L.2    Alonso, M.J.3
  • 40
    • 0029819323 scopus 로고    scopus 로고
    • Pharmaceutical application of cyclodextrins. 1. Drug solubilization and stability
    • T. Loftsson and M. E. Brewster, Pharmaceutical application of cyclodextrins. 1. Drug solubilization and stability. J. Pharm. Sci. 85, 1017 (1996).
    • (1996) J. Pharm. Sci. , vol.85 , pp. 1017
    • Loftsson, T.1    Brewster, M.E.2
  • 41
    • 0030728316 scopus 로고    scopus 로고
    • Cellular stress and apoptosis. Toxicol
    • M. Pallardy, M. Perrin-Wolff, and A. Biola, Cellular stress and apoptosis. Toxicol. In Vitro 11, 573 (1997).
    • (1997) Vitro , vol.11 , pp. 573
    • Pallardy, M.1    Perrin-Wolff, M.2    Biola, A.3


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