Antioestrogenic effect of trans-dehydrocrotonin, a nor-clerodane diterpene from Croton cajucara benth. in rats

Phytotherapy Research

Volumn 13, Issue 8, 1999, Pages 689-691

  Luna Costa, A M ^a   Silva, J C R ^a   Campos, A R ^a   Rao, V S N ^a   Maciel, M A M ^b   Pinto, A C ^b  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antioestrogen; Blastocyst implantation; Croton cajucara; Nor clerodane diterpene; Trans dehydrocrotonin

Indexed keywords

ANTIESTROGEN; CROTON CAJUCARA EXTRACT; DEHYDROCROTONIN; DITERPENE; ESTROGEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; MENSTRUAL CYCLE; NIDATION; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; UTERUS WEIGHT;

CROTON CAJUCARA;

EID: 0032796882     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199912)13:8<689::AID-PTR532>3.0.CO;2-L     Document Type: Article

References (25)

1. Acker, G., Hecquet, F., Etienne, A., Braquet, P., and Mencia-Huerta, J. M. (1988). Role of platelet activating factor (PAF) in the ovoimplantation in the rat: Effect of the specific PAF-acether antagonist BN 52021. Prostaglandins 35, 233-241.
2. Calhoun, F. J., Toison, W. W., and Schrogie, J. J. (1971). Effect of various drugs on the uterotrophic response to mestranol and norethynodrel in the rat. Proc. Soc. Exp. Biol. Med 136, 47-50.
3. Carvalho, J. C. T., Silva, M. F. C., Maciel, M. A. M. et al. (1996). Investigation of anti-inflammatory and antinociceptive activities of trans-dehydrocrotonin, a 19-nor-clerodane diterpene from Croton cajucara. Planta Med. 62, 402-404.
4. Di Stasi, L. C., Santos, E. M. G., Santos, C. M., and Hiruma, A. C. (1989). Plantas Medicinais na Amazônia, pp. 127-128, Editora Fundação Para o Desenvolvimento da Universidade Estadual Paulista, São Paulo.
5. Dey, S. K., and Johnson, D. C. (1980). Embryo-uterine interaction in implantation. Life Sci. 27, 2381-2384.
6. Emmens, C. W. (1970). Post-coital contraception. Br. Med. Bull. 26, 45-51.
7. Farias, R. A. F., Neto, M. F. O., Viana, G. S. B., and Rao, V. S. N. (1996). Effects of Croton cajucara extract on serum lipids of rats fed a high fat diet. Phytother. Res. 10, 697-699.
8. Farias, R. A. F., Rao, V. S. N., Viana, G. S. B., Silveira, E. R., Maciel, M. A. M., and Pinto, A. C. (1997). Hypoglycemic effect of trans-dehydrocrotonin, a nor-clerodane diterpene from Croton cajucara. Planta Med. 63, 558-560.
9. Harper, M. J. K., and Walpole, A. L. (1967). Mode of action of ICI 46,474 in preventing implantation in rats. J. Endocrinol. 37, 83-92.
10. Hideji, L, Ichihara, Y., and Kojima, H. (1989). Nor-clerodane diterpenes from Croton cajucara. Phytochemistry 28, 1667-1669.
11. Huppert, L C. (1979). Induction of ovulation with clomiphene citrate. Fertil. Steril. 31, 1-8.
12. Jaiyesimi, I. A., Buzdar, A. U., Decker, D. A., and Hortobagyi, G. N. (1995). Use of tamoxifen for breast cancer: twenty-eight years later. J. Clin. Oncol. 13, 513-529.
13. Jordon, V. C. (1995). An overview of considerations for the testing of tamoxifen as a preventive for breast cancer. Ann. New York Acad. Sci. 768, 141-147.
14. Kellen, J. A. (1996). Tamoxifen: Beyond the Antioestrogen. Birkhäuser Verlag, Berlin, 392pp.
15. Kennedy, T. G. (1977). Evidence for a role for prostaglandins in the initiation of blastocyst implantation in the rat. Biol. Reprod. 16, 286-291.
16. Kubo, I., Asaka, Y., and Shibata, K. (1991). Insect growth inhibitory norditerpenes, cis-dehydrocrotonin and transdehydrocrotonin, from Croton cajucara. Phytochemistry 30, 2545-2546.
17. Maciel, M. A. M., Pinto, A. C., and Grynberg, N. F. (1996). Atividade antitumoral da desidrocrotonina, un diterpeno nor-clerodano de Croton cajucara. XI Reunião da FeSBE, Resumos p. 417. Caxambu, Brasil.
18. Martins, J. E. C. (1989). Plantas Medicinais de uso na Amazônia, p. 92, Centro de Estudos Jurídicos do Pará, Belém.
19. Nicholson, R. I., Eaton, C. L., and Mannining, D. L. (1992). In, Recent Advances in Endocrinology and Metabolism, ed. by C. Edwards and D. Lincoln, pp. 151-165, Churchill Livingstone, Edinburgh.
20. O'Malley, B. W., and Means, A. R. (1974). Female steroid hormones and target cell nuclei. Science 183, 610-620.
21. Osborne, C. K., Wiebe, V. J., McGuire, W. L, Ciocca, D. R., and DeGregorio, M. W. (1992). Tamoxifen and the isomers of 4-hydroxytamoxifen in tamoxifen-resistant tumors from breast cancer patients. Clin. Oncol. 10, 304-310.
22. Parker, M. G. (1986). Mechanism of steroid hormone action. Cancer Surv. 5, 625-633.
23. Rao, V. S. N., Siva, J. C. R., and Medeiros, F. C. (1995). Effects of anti-inflammatory plant extracts on ovoimplantation in rats. Phytother. Res. 9, 458-459.
24. Sahlin, L, Norstedt, G., and Eriksson, H. (1994). Estrogen regulation of the estrogen receptor and insulin like growth factor-1 in the rat uterus: a potential coupling between effects of estrogen and IGF-1. Steroids 59, 421-430.
25. Simões, J. C., Rebeiro, A. J. S., Serruya, H., and Bentes, M. H. S. (1979). Desidrocrotonina, um diterpeno de croton cajucara Benth. (Euphorbiaceae). Ciênciae Culture 31, 1140-1141.