Reactive oxygen species responsive nanoprodrug to treat intracranial glioblastoma

ACS Nano

Volumn 7, Issue 4, 2013, Pages 3061-3077

  Lee, Bong Seop ^a   Amano, Takayuki ^a   Wang, Hong Qiang ^a   Pantoja, Joe L ^a   Yoon, Chi Woo ^a   Hanson, Christopher J ^a   Amatya, Rina ^a   Yen, Allen ^a   Black, Keith L ^a   Yu, John S ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

drug delivery; EPR effect; glioblastoma; nanoplatform; nanoprodrug; nonendosomal cellular uptake; targeted cancer therapy

Indexed keywords

CELLULAR UPTAKE; EPR EFFECT; GLIOBLASTOMAS; NANOPLATFORM; NANOPRODRUG; TARGETED CANCER THERAPY;

BRAIN; CELL MEMBRANES; CHEMOTHERAPY; CYTOLOGY; DRUG DELIVERY; ENZYME ACTIVITY; ENZYME INHIBITION; MAMMALS; MOLECULAR BIOLOGY; OPTIMIZATION;

TUMORS;

ALPHA TOCOPHEROL; ANTIOXIDANT; CAMPTOTHECIN; NANOCAPSULE; PRODRUG; REACTIVE OXYGEN METABOLITE;

ANIMAL; ARTICLE; BRAIN TUMOR; CHEMISTRY; GLIOBLASTOMA; METABOLISM; MOUSE; PATHOLOGY; TREATMENT OUTCOME; TUMOR CELL LINE; ULTRASTRUCTURE; BRAIN NEOPLASMS;

ALPHA-TOCOPHEROL; ANIMALS; ANTIOXIDANTS; BRAIN NEOPLASMS; CAMPTOTHECIN; CELL LINE, TUMOR; GLIOBLASTOMA; MICE; NANOCAPSULES; PRODRUGS; REACTIVE OXYGEN SPECIES; TREATMENT OUTCOME;

EID: 84876517205     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn400347j     Document Type: Article

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