Complementary detection of embryotoxic properties of substances in the neural and cardiac embryonic stem cell tests

Toxicological Sciences

Volumn 132, Issue 1, 2013, Pages 118-130

  Theunissen, Peter T ^a,b   Pennings, Jeroen L A ^a,c   van Dartel, Dorien A M ^a,b,d   Robinson, Joshua F ^a,b,c   Kleinjans, Jos C S ^b,c   Piersma, Aldert H ^a,c,e  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c Netherlands Toxicogenomics Centre   (Netherlands)

^d WAGENINGEN UNIVERSITY   (Netherlands)

^e UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Alternative test method; Embryonic stem test; Neural embryonic stem cell test; Toxicogenomics; Transcriptomics gene expression analysis

Indexed keywords

CARBAMAZEPINE; FLUSILAZOLE; HEXACONAZOLE; METHYLMERCURY; MONOETHYLHEXYLPHTHALATE; PENICILLIN G; PHTHALIC ACID; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARDIAC EMBRYONIC STEM CELL TEST; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; EMBRYONIC STEM CELL; EMBRYOTOXICITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEART; IMMUNE FUNCTION TEST; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF DETECTION; NEURAL EMBRYONIC STEM CELL TEST; NEURAL STEM CELL; NONHUMAN; TOXICITY TESTING; TOXICOGENETICS; TRANSCRIPTOMICS;

ANIMALS; EMBRYONIC STEM CELLS; GENE EXPRESSION; MYOCYTES, CARDIAC; NEURAL STEM CELLS; TERATOGENS; TOXICITY TESTS;

ANIMALIA;

EID: 84876488480     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs333     Document Type: Article

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