Evaluation of the embryotoxic potency of compounds in a newly revised high throughput embryonic stem cell test

Toxicological Sciences

Volumn 105, Issue 2, 2008, Pages 342-350

  Peters, Annelieke K ^a   Steemans, Margino ^a   Hansen, Erik ^a   Mesens, Natalie ^a   Verheyen, Geert R ^a   Vanparys, Philippe ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

D3; Embryonic stem cells; EST; Relative Embryotoxic Potency; REP

Indexed keywords

6 AMINONICOTINAMIDE; ACRYLAMIDE; BORIC ACID; FLUOROURACIL; HYDROXYUREA; LITHIUM CHLORIDE; METHOXYACETIC ACID; METHYLMERCURIC CHLORIDE; PENICILLIN G; SACCHARIN; TOXIC SUBSTANCE; VALPROIC ACID;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYONIC STEM CELL; EMBRYOTOXICITY; HEART MUSCLE CELL; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC STEM CELLS; MICE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; REPRODUCIBILITY OF RESULTS; TERATOGENS; TOXICITY TESTS;

MURINAE;

EID: 51849160448     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn126     Document Type: Article

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