Circulating endogenous retinoic acid concentrations among participants enrolled in a randomized placebo-controlled clinical trial of retinyl palmitate

Cancer Epidemiology Biomarkers and Prevention

Volumn 13, Issue 11, 2004, Pages 1687-1692

  Sedjo, Rebecca L ^a   Ranger Moore, James ^a,b   Foote, Janet ^c   Craft, Neal E ^d   Alberts, David S ^a   Xu, Min Jian ^a   Giuliano, Anna R ^a,b,e  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^d Craft Technologies Inc   (United States)

^e H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CAROTENE; PLACEBO; RETINOIC ACID; RETINOL PALMITATE;

ACTINIC KERATOSIS; ADULT; AGED; ARTICLE; BLOOD SAMPLING; CHEMOPROPHYLAXIS; CIS ISOMER; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH RISK POPULATION; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN CANCER; TRANS ISOMER; VITAMIN SUPPLEMENTATION;

AGED; ANTICARCINOGENIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS; SKIN NEOPLASMS; STEREOISOMERISM; TRETINOIN; VITAMIN A;

EID: 8344225289     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Roos TH, Jugert FK, Merk HF, Bickers DR. Retinoid metabolism in the skin. Pharmacol Rev 1998;50:315-33.
2. Moon TE, Levin N, Cartmel B, et al. The Southwest Skin Cancer Prevention Group. Effect of retinol in preventing squamous cell skin cancer in moderate-risk subjects: a randomized, double-blind, controlled trial. Cancer Epidemiol Biomarkers Prev 1997;6:949-56.
3. Hong WK, Endicott J, Itri LM, et al. 13-Cis-retinoic acid in the treatment of oral leukoplakia. N Engl J Med 1986;315:1501-5.
4. Hong WL, Lippman SM, Itri LM, et al. Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N Engl J Med 1990;323:795-801.
5. Lippman SM, Benner SE, Hong WK. Chemoprevention strategies for the control of cancer. Cancer 1993;72:984-90.
6. Meyskens FL Jr, Surwit E, Moon TE, et al. Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: a randomized trial. J Natl Cancer Inst 1994;86:539-43.
7. Giuliano A, Gasptur S, Garewal H. Chemoprevention and vitamins: clinical trials. In: Bertino J, editor. Encyclopedia of cancer. San Diego, CA: Academy Press, Inc.; 1996.
8. Niles RM. Recent advances in the use of vitamin A (retinoids) in the prevention and treatment of cancer. Nutrition 2000;16:1084-9.
9. Sun SY, Lotan R. Retinoids and their receptors in cancer development and chemoprevention. Crit Rev Oncol Hematol 2002;41:41-55.
10. Lammer EJ, Chen DT, Hoar RM, et al. Retinoic acid embryopathy. N Engl J Med 1985;313:837-41.
11. Tangrea JA, Edwards BK, Taylor PR, et al. Long-term therapy with low-dose isotretinoin for prevention of basal cell carcinoma: a multicenter clinical trial. J Natl Cancer Inst 1992;84:328-32.
12. Zusi FC, Lorenzi MV, Vivat-Hannah V. Selective retinoids and rexinoids in cancer therapy and chemoprevention. Drug Discov Today 2002;7:1165-74.
13. Kurlandsky SB, Xiao JH, Duell EA, Voorhees JJ, Fisher GJ. Biological activity of all-trans retinol requires metabolic conversion to all-trans-retinoic acid and is mediated through activation of nuclear retinoid receptors in human keratinocytes. J Biol Chem 1994;269:32821-7.
14. Tang G, Russell RM. 13-Cis-retinoic acid is an endogenous compound in human serum. J Lipid Res 1990;31:175-82.
15. Wyss R, Bucheli F. Determination of endogenous levels of 13-cis-retinoic acid (isotretinoin), all-trans-retinoic acid (tretinoin) and their 4-oxo metabolites in human and animal plasma by high-performance liquid chromatography with automated column switching and ultraviolet detection. J Chromatogr B 1997;700:31-47.
16. Tang G, Russell RM. Formation of all-trans-retinoic acid and 13-ris-retinoic acid from all-trans-retinyl palmitate in humans. J Nutr Biochem 1991;2:210-3.
17. Alberts DS, Einspahr J, Frank D, et al. Cost- and time-efficient evaluation of chemoprevention agent efficacy. AACR Conference on Frontiers in Cancer Prevention Research; 2002 Oct 14-18; Boston, MA.
18. Alberts DS, Ranger-Moore J, Einspahr J, et al. Safety and efficacy of dose intensive oral vitamin A in subjects with sun-damaged skin. Clin Cancer Res 2004;10:1875-80.
19. Xu MJ, Alberts DS, Peng YM, Liu Y, Canfield LM. Simultaneous analysis of plasma retinol, retinyl palmitate, δ-, γ-, α-tocopherols and six major carotenoids by isocratic non-aqueous reversed-phase HPLC method [abstract]. Proc AACR 1996;37:277.
20. Stata Corp. Stata statistical software: release 7.0. College Station (TX): Stata Corp.; 2001.
21. SAS Institute, Inc. SAS/STAT software: changes and enhancements, release 8.1. Cary (NC): SAS Institute, Inc.; 2000.
22. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington (IX): National Academy Press; 2002. p. 82-161.
23. Russell RM. β-Carotene and lung cancer. Pure Appl Chem 2002;74:1461-7.
24. Chambon P. A decade of molecular biology of rerinoic acid receptors. FASEB J 1996;10:940-54.
25. Soprano DR, Soprano KJ. Pharmacological doses of some synthetic rennoids can modulate both the aryl hydrocarbon receptor and retinoid receptor pathway. J Nutr 2003;133:277-81S.
26. Kastner P, Chambon P, Leid M. Role of nuclear rerinoic acid receptors in the regulation of gene expression. In: Blomhoff J, editor. Vitamin A in health and disease. New York (NY): Marcel Dekker, Inc.; 1994. p. 189-238.
27. Berg WJ, Nanus DM, Leung A, et al. Up-regulation of rerinoic acid receptor β expression in renal cancers in vivo correlates with response to 13-ris-rerinoic acid and interferon-α-2a. Clin Cancer Res 1999;5:1671-5.
28. Xu XC, Lee JS, Lee JJ, et al. Nuclear retinoid acid receptor β in bronchial epithelium of smokers before and during chemoprevention. J Natl Cancer Inst 1999;91:1317-21.
29. Lotan R, Xu XC, Lippman SM, et al. Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isotretinoin. N Engl J Med 1995;332:1405-10.
30. Ayoub J, Jean-Francois R, Cormier Y, et al. Placebo-controlled trial of 13-cis-retinoic acid activity on retinoic acid receptor-β expression in a population at high risk: implications for chemoprevention of lung cancer. J Clin Oncol 1999;17:3546-52.