Regulation of miR-155 biogenesis in cystic fibrosis lung epithelial cells: Antagonistic role of two mRNA-destabilizing proteins, KSRP and TTP

Biochemical and Biophysical Research Communications

Volumn 433, Issue 4, 2013, Pages 484-488

  Bhattacharyya, Sharmistha ^a   Kumar, Parameet ^a,b   Tsuchiya, Motohiro ^c   Bhattacharyya, Anirban ^a   Biswas, Roopa ^a  

^a Uniformed Services University of the Health Sciences   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Cystic fibrosis; Inflammation; MicroRNA; MiRNA processing; RNA binding proteins

Indexed keywords

MEMBRANE PROTEIN; MESSENGER RNA; MICRORNA 155; PROTEIN KSRP; PROTEIN TTP; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CONTROLLED STUDY; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INHIBITION KINETICS; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL LINE, TUMOR; CYSTIC FIBROSIS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPRECIPITATION; INFLAMMATION; LUNG; MICRORNAS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; TRANS-ACTIVATORS; TRANSFECTION; TRISTETRAPROLIN;

EID: 84876476808     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.025     Document Type: Article

References (41)

1. Pollard H.B. Anatomic genomics: systems of genes supporting the biology of systems. Anat. Rec. 2000, 259:FM3-FM9.
2. Frizzell R.A. Ten years with CFTR. Physiol. Rev. 1999, 79:S1-2.
3. Cheng S.H., Gregory R.J., Marshall J., Paul S., Souza D.W., White G.A., O'Riordan C.R., Smith A.E. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell 1990, 63:827-834.
4. Kopito R.R. Biosynthesis and degradation of CFTR. Physiol. Rev. 1999, 79:S167-173.
5. Dean T.P., Dai Y., Shute J.K., Church M.K., Warner J.O. Interleukin-8 concentrations are elevated in bronchoalveolar lavage, sputum, and sera of children with cystic fibrosis. Pediatr. Res. 1993, 34:159-161.
6. Richman-Eisenstat J.B., Jorens P.G., Hebert C.A., Ueki I., Nadel J.A. Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases. Am. J. Physiol. 1993, 264:L413-418.
7. Armstrong D.S., Grimwood K., Carlin J.B., Carzino R., Gutierrez J.P., Hull J., Olinsky A., Phelan E.M., Robertson C.F., Phelan P.D. Lower airway inflammation in infants and young children with cystic fibrosis. Am. J. Respir. Crit. Care Med. 1997, 156:1197-1204.
8. Roebuck K.A. Regulation of interleukin-8 gene expression. J. Interferon Cytokine Res. 1999, 19:429-438.
9. Bonfield T.L., Panuska J.R., Konstan M.W., Hilliard K.A., Hilliard J.B., Ghnaim H., Berger M. Inflammatory cytokines in cystic fibrosis lungs. Am. J. Respir. Crit. Care Med. 1995, 152:2111-2118.
10. Corvol H., Fitting C., Chadelat K., Jacquot J., Tabary O., Boule M., Cavaillon J.M., Clement A. Distinct cytokine production by lung and blood neutrophils from children with cystic fibrosis. Am. J. Physiol. Lung Cell Mol. Physiol. 2003, 284:L997-1003.
11. Ambros V. MicroRNAs: tiny regulators with great potential. Cell 2001, 107:823-826.
12. Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 2003, 113:673-676.
13. Ambros V. The functions of animal microRNAs. Nature 2004, 431:350-355.
14. von Roretz C., Gallouzi I.E. Decoding ARE-mediated decay: is microRNA part of the equation?. J. Cell Biol. 2008, 181:189-194.
15. Bhattacharyya S.N., Habermacher R., Martine U., Closs E.I., Filipowicz W. Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells. Cold Spring Harbor Symp. Quant. Biol. 2006, 71:513-521.
16. Vasudevan S., Tong Y., Steitz J.A. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007, 318:1931-1934.
17. Poy M.N., Eliasson L., Krutzfeldt J., Kuwajima S., Ma X., Macdonald P.E., Pfeffer S., Tuschl T., Rajewsky N., Rorsman P., Stoffel M. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 2004, 432:226-230.
18. Poy M.N., Spranger M., Stoffel M. MicroRNAs and the regulation of glucose and lipid metabolism. Diabetes Obes. Metab. 2007, 9(Suppl 2):67-73.
19. Blenkiron C., Goldstein L.D., Thorne N.P., Spiteri I., Chin S.F., Dunning M.J., Barbosa-Morais N.L., Teschendorff A.E., Green A.R., Ellis I.O., Tavare S., Caldas C., Miska E.A. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol. 2007, 8:R214.
20. Blenkiron C., Miska E.A. MiRNAs in cancer: approaches, aetiology, diagnostics and therapy. Hum. Mol. Genet. 2007, 16(1):R106-R113.
21. Hwang H.W., Mendell J.T. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br. J. Cancer 2006, 94:776-780.
22. Jovanovic M., Hengartner M.O. MiRNAs and apoptosis: RNAs to die for. Oncogene 2006, 25:6176-6187.
23. van Rooij E., Olson E.N. MicroRNAs put their signatures on the heart. Physiol. Genomics 2007, 31:365-366.
24. Ikeda S., Kong S.W., Lu J., Bisping E., Zhang H., Allen P.D., Golub T.R., Pieske B., Pu W.T. Altered microRNA expression in human heart disease. Physiol. Genomics 2007, 31:367-373.
25. Rane S., Sayed D., Abdellatif M. MicroRNA with a macrofunction. Cell Cycle 2007, 6:1850-1855.
26. Kim V.N. MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol. 2005, 6:376-385.
27. Kim V.N. Small RNAs: classification, biogenesis, and function. Mol. Cells 2005, 19:1-15.
28. Bagga S., Pasquinelli A.E. Identification and analysis of microRNAs. Genet. Eng. (NY) 2006, 27:1-20.
29. Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 11:597-610.
30. Slezak-Prochazka I., Durmus S., Kroesen B.J., van den Berg A. MicroRNAs, macrocontrol: regulation of miRNA processing. RNA 2010, 16:1087-1095.
31. Bhattacharyya S., Balakathiresan N.S., Dalgard C., Gutti U., Armistead D., Jozwik C., Srivastava M., Pollard H.B., Biswas R. Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyperexpression of interleukin-8. J. Biol. Chem. 2011, 286:11604-11615.
32. Balakathiresan N.S., Bhattacharyya S., Gutti U., Long R.P., Jozwik C., Huang W., Srivastava M., Pollard H.B., Biswas R. Tristetraprolin regulates IL-8 mRNA stability in cystic fibrosis lung epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 2009, 296:L1012-1018.
33. Chen C.Y., Gherzi R., Ong S.E., Chan E.L., Raijmakers R., Pruijn G.J., Stoecklin G., Moroni C., Mann M., Karin M. AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell 2001, 107:451-464.
34. Carballo E., Lai W.S., Blackshear P.J. Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin. Science 1998, 281:1001-1005.
35. Carrick D.M., Lai W.S., Blackshear P.J. The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis. Arthritis Res. Ther. 2004, 6:248-264.
36. Eidelman O., Srivastava M., Zhang J., Leighton X., Murtie J., Jozwik C., Jacobson K., Weinstein D.L., Metcalf E.L., Pollard H.B. Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the TNF-alphaR/NFkappaB pathway. Mol. Med. 2001, 7:523-534.
37. Ruggiero T., Trabucchi M., De Santa F., Zupo S., Harfe B.D., McManus M.T., Rosenfeld M.G., Briata P., Gherzi R. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J. 2009, 23:2898-2908.
38. van Rooij E., Olson E.N. MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. J. Clin. Invest. 2007, 117:2369-2376.
39. Iorio M.V., Ferracin M., Liu C.G., Veronese A., Spizzo R., Sabbioni S., Magri E., Pedriali M., Fabbri M., Campiglio M., Menard S., Palazzo J.P., Rosenberg A., Musiani P., Volinia S., Nenci I., Calin G.A., Querzoli P., Negrini M., Croce C.M. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005, 65:7065-7070.
40. Michlewski G., Guil S., Caceres J.F. Stimulation of pri-miR-18a Processing by hnRNP A1. Adv. Exp. Med. Biol. 2005, 700:28-35.
41. Michlewski G., Caceres J.F. Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat. Struct. Mol. Biol. 2010, 17:1011-1018.