COX-1-dependent prostaglandin D2 in microglia contributes to neuropathic pain via DP2 receptor in spinal neurons

GLIA

Volumn 61, Issue 6, 2013, Pages 943-956

  Kanda, Hirosato ^a   Kobayashi, Kimiko ^a   Yamanaka, Hiroki ^a   Noguchi, Koichi ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Axotomy; Dorsal horn; Glial cells; Lipid mediator; Neuropathic pain

Indexed keywords

3 BENZYL 5 (6 CARBOXYHEXYL) 1 (2 CYCLOHEXYL 2 HYDROXYETHYLAMINO)HYDANTOIN; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; DP2 RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; OZAGREL; PROSTAGLANDIN D2; RECEPTOR; THROMBOXANE A2; THROMBOXANE SYNTHASE; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLIA CELL; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICROGLIA; NERVE FIBER TRANSECTION; NEUROPATHIC PAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL;

ANIMALS; BEHAVIOR, ANIMAL; CYCLOOXYGENASE 1; HYPERALGESIA; MALE; MICROGLIA; NEURALGIA; NEURONS; PAIN MEASUREMENT; PROSTAGLANDIN D2; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PROSTAGLANDIN; SPINAL CORD;

EID: 84876473212     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22487     Document Type: Article

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