메뉴 건너뛰기




Volumn 132, Issue 1, 2013, Pages 1-7

Don't judge a neuron only by its cover: Neuronal function in in vitro developmental neurotoxicity testing

Author keywords

In vitro methods; Intercellular and intracellular communication; Neural progenitor cells; Neurodevelopmental disorders; Neuronal network function; Risk assessment

Indexed keywords

ADVERSE OUTCOME; APOPTOSIS; ARTICLE; BIOCHEMISTRY; BRAIN DEVELOPMENT; CELL COMMUNICATION; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHEMICAL ANALYSIS; CHEMICALLY INDUCED DISORDER; COGNITION; DENDRITE; DEVELOPMENTAL NEUROTOXICITY; ELECTRODE; ELECTROPHYSIOLOGY; HUMAN; IN VITRO STUDY; INTRACELLULAR SIGNALING; MEDICAL DECISION MAKING; MOLECULAR MECHANICS; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE FIBER; NEURAL STEM CELL; NEUROPROTECTION; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; RISK ASSESSMENT; STEM CELL; SYNAPTOGENESIS;

EID: 84876464283     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs269     Document Type: Article
Times cited : (37)

References (53)
  • 1
    • 0024160475 scopus 로고
    • Effects of neurotoxicants on synaptic transmission: Lessons learned from electrophysiological studies
    • Atchison, W. D. (1988). Effects of neurotoxicants on synaptic transmission: Lessons learned from electrophysiological studies. Neurotoxicol. Teratol. 10, 393-416.
    • (1988) Neurotoxicol. Teratol. , vol.10 , pp. 393-416
    • Atchison, W.D.1
  • 3
    • 84864516371 scopus 로고    scopus 로고
    • Comparing the population neurodevelopmental burdens associated with children's exposures to environmental chemicals and other risk factors
    • Bellinger, D. C. (2012). Comparing the population neurodevelopmental burdens associated with children's exposures to environmental chemicals and other risk factors. Neurotoxicology 33, 641-643.
    • (2012) Neurotoxicology , vol.33 , pp. 641-643
    • Bellinger, D.C.1
  • 4
    • 79953180902 scopus 로고    scopus 로고
    • Assessing mitochondrial dysfunction in cells
    • Brand, M. D., and Nicholls, D. G. (2011). Assessing mitochondrial dysfunction in cells. Biochem. J. 435, 297-312.
    • (2011) Biochem. J. , vol.435 , pp. 297-312
    • Brand, M.D.1    Nicholls, D.G.2
  • 5
    • 73649102801 scopus 로고    scopus 로고
    • Neural progenitor cells as models for highthroughput screens of developmental neurotoxicity: State of the science
    • Breier, J. M., Gassmann, K., Kayser, R., Stegeman, H., De Groot, D., Fritsche, E., and Shafer, T. J. (2010). Neural progenitor cells as models for highthroughput screens of developmental neurotoxicity: State of the science. Neurotoxicol. Teratol. 32, 4-15.
    • (2010) Neurotoxicol. Teratol. , vol.32 , pp. 4-15
    • Breier, J.M.1    Gassmann, K.2    Kayser, R.3    Stegeman, H.4    De Groot, D.5    Fritsche, E.6    Shafer, T.J.7
  • 6
    • 49249113004 scopus 로고    scopus 로고
    • Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells
    • Breier, J. M., Radio, N. M., Mundy, W. R., and Shafer, T. J. (2008). Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells. Toxicol. Sci. 105, 119-133.
    • (2008) Toxicol. Sci. , vol.105 , pp. 119-133
    • Breier, J.M.1    Radio, N.M.2    Mundy, W.R.3    Shafer, T.J.4
  • 7
    • 2942525466 scopus 로고    scopus 로고
    • Using FM1-43 to study neuropeptide granule dynamics and exocytosis
    • Brumback, A. C., Lieber, J. L., Angleson, J. K., and Betz, W. J. (2004). Using FM1-43 to study neuropeptide granule dynamics and exocytosis. Methods 33, 287-294.
    • (2004) Methods , vol.33 , pp. 287-294
    • Brumback, A.C.1    Lieber, J.L.2    Angleson, J.K.3    Betz, W.J.4
  • 9
    • 78650071220 scopus 로고    scopus 로고
    • Mitochondria and neuroplasticity
    • Cheng, A., Hou, Y., and Mattson, M. P. (2010). Mitochondria and neuroplasticity. ASN Neuro 2, 243-256.
    • (2010) ASN Neuro , vol.2 , pp. 243-256
    • Cheng, A.1    Hou, Y.2    Mattson, M.P.3
  • 11
    • 36549075574 scopus 로고    scopus 로고
    • Synaptic plasticity: Multiple forms, functions, and mechanisms
    • Citri, A., and Malenka, R. C. (2008). Synaptic plasticity: Multiple forms, functions, and mechanisms. Neuropsychopharmacology 33, 18-41.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 18-41
    • Citri, A.1    Malenka, R.C.2
  • 13
    • 84876494927 scopus 로고    scopus 로고
    • Chapter: 13 In vitro approaches to developmental neurotoxicity
    • 1st ed. (R. C. Gupta, Ed.)
    • Costa, L. G., Giordano, G., and Guizetti, M. (2011). Chapter 13: In vitro approaches to developmental neurotoxicity. In Reproductive and Developmental Toxicology, 1st ed. (R. C. Gupta, Ed.), pp. 159-166.
    • (2011) Reproductive and Developmental Toxicology , pp. 159-166
    • Costa, L.G.1    Giordano, G.2    Guizetti, M.3
  • 14
    • 79958270042 scopus 로고    scopus 로고
    • Developmental neurotoxicity testing: Recommendations for developing alternative methods for the screening and prioritization of chemicals
    • Academic Press
    • Academic Press, San Diego, CA. Crofton, K. M., Mundy, W. R., Lein, P. J., Bal-Price, A., Coecke, S., Seiler, A. E., Knaut, H., Buzanska, L., and Goldberg, A. (2011). Developmental neurotoxicity testing: Recommendations for developing alternative methods for the screening and prioritization of chemicals. ALTEX 28, 9-15.
    • (2011) ALTEX , vol.28 , pp. 9-15
    • San Diego, C.A.1    Crofton, K.M.2    Mundy, W.R.3    Lein, P.J.4    Bal-Price, A.5    Coecke, S.6    Seiler, A.E.7    Knaut, H.8    Buzanska, L.9    Goldberg, A.10
  • 15
    • 84871716691 scopus 로고    scopus 로고
    • Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells
    • Culbreth, M. E., Harrill, J. A., Freudenrich, T. M., Mundy, W. R., and Shafer, T. J. (forthcoming). Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells. Neurotoxicology. Advance Access published May 25, 2012. doi: 10.1016/j.neuro.2012.05.012.
    • (2012) Neurotoxicology
    • Culbreth, M.E.1    Harrill, J.A.2    Freudenrich, T.M.3    Mundy, W.R.4    Shafer, T.J.5
  • 19
    • 0034007441 scopus 로고    scopus 로고
    • Neonatal exposure to neurotoxic pesticides increases adult susceptibility: A review of current findings
    • Eriksson, P., and Talts, U. (2000). Neonatal exposure to neurotoxic pesticides increases adult susceptibility: A review of current findings. Neurotoxicology 21, 37-47.
    • (2000) Neurotoxicology , vol.21 , pp. 37-47
    • Eriksson, P.1    Talts, U.2
  • 20
    • 58149334892 scopus 로고    scopus 로고
    • Communication between neurons and astrocytes: Relevance to the modulation of synaptic and network activity
    • Fellin, T. (2009). Communication between neurons and astrocytes: Relevance to the modulation of synaptic and network activity. J. Neurochem. 108, 533-544.
    • (2009) J. Neurochem. , vol.108 , pp. 533-544
    • Fellin, T.1
  • 21
    • 61849113819 scopus 로고    scopus 로고
    • Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71
    • Giordano, G., Kavanagh, T. J., and Costa, L. G. (2009). Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71. Neurotoxicology 30, 326-329.
    • (2009) Neurotoxicology , vol.30 , pp. 326-329
    • Giordano, G.1    Kavanagh, T.J.2    Costa, L.G.3
  • 23
    • 80855131654 scopus 로고    scopus 로고
    • Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth
    • Harrill, J. A., Freudenrich, T. M., Robinette, B. L., and Mundy, W. R. (2011a). Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth. Toxicol. Appl. Pharmacol. 256, 268-280.
    • (2011) Toxicol. Appl. Pharmacol. , vol.256 , pp. 268-280
    • Harrill, J.A.1    Freudenrich, T.M.2    Robinette, B.L.3    Mundy, W.R.4
  • 24
    • 78650524432 scopus 로고    scopus 로고
    • Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro
    • Harrill, J. A., Robinette, B. L., and Mundy, W. R. (2011b). Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro. Toxicol. In Vitro 25, 368-387.
    • (2011) Toxicol. In Vitro , vol.25 , pp. 368-387
    • Harrill, J.A.1    Robinette, B.L.2    Mundy, W.R.3
  • 26
    • 77949368541 scopus 로고    scopus 로고
    • Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders
    • Herbert, M. R. (2010). Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders. Curr. Opin. Neurol. 23, 103-110.
    • (2010) Curr. Opin. Neurol. , vol.23 , pp. 103-110
    • Herbert, M.R.1
  • 27
    • 18144398925 scopus 로고    scopus 로고
    • Differences in the magnitude of long-term potentiation produced by theta burst and high frequency stimulation protocols matched in stimulus number
    • Hernandez, R. V., Navarro, M. M., Rodriguez, W. A., Martinez, J. L., Jr, and LeBaron, R. G. (2005). Differences in the magnitude of long-term potentiation produced by theta burst and high frequency stimulation protocols matched in stimulus number. Brain Res. Brain Res. Protoc. 15, 6-13.
    • (2005) Brain Res. Brain Res. Protoc , vol.15 , pp. 6-13
    • Hernandez, R.V.1    Navarro, M.M.2    Rodriguez, W.A.3    Martinez Jr., J.L.4    LeBaron, R.G.5
  • 28
    • 79960841058 scopus 로고    scopus 로고
    • Caveats and limitations of plate reader-based high-throughput kinetic measurements of intracellular calcium levels
    • Heusinkveld, H. J., and Westerink, R. H. (2011). Caveats and limitations of plate reader-based high-throughput kinetic measurements of intracellular calcium levels. Toxicol. Appl. Pharmacol. 255, 1-8.
    • (2011) Toxicol. Appl. Pharmacol. , vol.255 , pp. 1-8
    • Heusinkveld, H.J.1    Westerink, R.H.2
  • 29
    • 78951483473 scopus 로고    scopus 로고
    • Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: Evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons
    • Hogberg, H. T., Sobanski, T., Novellino, A., Whelan, M., Weiss, D. G., and Bal-Price, A. K. (2011). Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: Evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons. Neurotoxicology 32, 158-168.
    • (2011) Neurotoxicology , vol.32 , pp. 158-168
    • Hogberg, H.T.1    Sobanski, T.2    Novellino, A.3    Whelan, M.4    Weiss, D.G.5    Bal-Price, A.K.6
  • 30
    • 77953538605 scopus 로고    scopus 로고
    • Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century
    • Johnstone, A. F., Gross, G. W., Weiss, D. G., Schroeder, O. H., Gramowski, A., and Shafer, T. J. (2010). Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century. Neurotoxicology 31, 331-350.
    • (2010) Neurotoxicology , vol.31 , pp. 331-350
    • Johnstone, A.F.1    Gross, G.W.2    Weiss, D.G.3    Schroeder, O.H.4    Gramowski, A.5    Shafer, T.J.6
  • 31
  • 32
    • 34249100959 scopus 로고    scopus 로고
    • Meeting report: Alternatives for developmental neurotoxicity testing
    • Lein, P., Locke, P., and Goldberg, A. (2007). Meeting report: Alternatives for developmental neurotoxicity testing. Environ. Health Perspect. 115, 764-768.
    • (2007) Environ. Health Perspect. , vol.115 , pp. 764-768
    • Lein, P.1    Locke, P.2    Goldberg, A.3
  • 33
    • 84867233159 scopus 로고    scopus 로고
    • Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set
    • (forthcoming). Advance Access published May 28 doi:10.1016/j.neuro.2012.05.001
    • McConnell, E. R., McClain, M. A., Ross, J., Lefew, W. R., and Shafer, T. J. (forthcoming). Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set. Neurotoxicology. Advance Access published May 28, 2012. doi: 10.1016/j.neuro.2012.05.001.
    • (2012) Neurotoxicology
    • McConnell, E.R.1    McClain, M.A.2    Ross, J.3    Lefew, W.R.4    Shafer, T.J.5
  • 35
    • 52049106127 scopus 로고    scopus 로고
    • Multiple roles of calcium ions in the regulation of neurotransmitter release
    • Neher, E., and Sakaba, T. (2008). Multiple roles of calcium ions in the regulation of neurotransmitter release. Neuron 59, 861-872.
    • (2008) Neuron , vol.59 , pp. 861-872
    • Neher, E.1    Sakaba, T.2
  • 37
    • 84864763551 scopus 로고    scopus 로고
    • OECD. No. 426 Developmental Neurotoxicity Study
    • OECD. (2007). Guideline for testing of chemicals, No. 426 "Developmental Neurotoxicity Study."
    • (2007) Guideline for testing of chemicals
  • 38
    • 84864039926 scopus 로고    scopus 로고
    • An optimized gene set for transcriptomics based neurodevelopmental toxicity prediction in the neural embryonic stem cell test
    • Pennings, J. L., Theunissen, P. T., and Piersma, A. H. (2012). An optimized gene set for transcriptomics based neurodevelopmental toxicity prediction in the neural embryonic stem cell test. Toxicology 300, 158-167.
    • (2012) Toxicology , vol.300 , pp. 158-167
    • Pennings, J.L.1    Theunissen, P.T.2    Piersma, A.H.3
  • 39
    • 49249116936 scopus 로고    scopus 로고
    • Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening
    • Radio, N. M., Breier, J. M., Shafer, T. J., and Mundy, W. R. (2008). Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening. Toxicol. Sci. 105, 106-118.
    • (2008) Toxicol. Sci. , vol.105 , pp. 106-118
    • Radio, N.M.1    Breier, J.M.2    Shafer, T.J.3    Mundy, W.R.4
  • 40
    • 73849133701 scopus 로고    scopus 로고
    • Comparison of PC12 and cerebellar granule cell cultures for evaluating neurite outgrowth using high content analysis
    • Radio, N. M., Freudenrich, T. M., Robinette, B. L., Crofton, K. M., and Mundy, W. R. (2010). Comparison of PC12 and cerebellar granule cell cultures for evaluating neurite outgrowth using high content analysis. Neurotoxicol. Teratol. 32, 25-35.
    • (2010) Neurotoxicol. Teratol. , vol.32 , pp. 25-35
    • Radio, N.M.1    Freudenrich, T.M.2    Robinette, B.L.3    Crofton, K.M.4    Mundy, W.R.5
  • 41
    • 44649176280 scopus 로고    scopus 로고
    • Developmental neurotoxicity testing in vitro: Models for assessing chemical effects on neurite outgrowth
    • Radio, N. M., and Mundy, W. R. (2008). Developmental neurotoxicity testing in vitro: Models for assessing chemical effects on neurite outgrowth. Neurotoxicology 29, 361-376.
    • (2008) Neurotoxicology , vol.29 , pp. 361-376
    • Radio, N.M.1    Mundy, W.R.2
  • 42
    • 0033911258 scopus 로고    scopus 로고
    • Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models
    • Rice, D., and Barone, S. Jr. (2000). Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models. Environ. Health Perspect. 108(Suppl. 3), 511-533.
    • (2000) Environ. Health Perspect. , vol.108 , Issue.SUPPL. 3 , pp. 511-533
    • Rice, D.1    Barone Jr., S.2
  • 43
    • 83755172909 scopus 로고    scopus 로고
    • In vitro assessment of developmental neurotoxicity: Use of microelectrode arrays to measure functional changes in neuronal network ontogeny
    • Robinette, B. L., Harrill, J. A., Mundy, W. R., and Shafer, T. J. (2011). In vitro assessment of developmental neurotoxicity: Use of microelectrode arrays to measure functional changes in neuronal network ontogeny. Front. Neuroeng. 4, 1.
    • (2011) Front. Neuroeng. , vol.4 , pp. 1
    • Robinette, B.L.1    Harrill, J.A.2    Mundy, W.R.3    Shafer, T.J.4
  • 44
    • 80755163616 scopus 로고    scopus 로고
    • Developmental toxicity testing in the 21st century: The sword of Damocles shattered by embryonic stem cell assays? Arch
    • Seiler, A., Oelgeschläger, M., Liebsch, M., Pirow, R., Riebeling, C., Tralau, T., and Luch, A. (2011). Developmental toxicity testing in the 21st century: The sword of Damocles shattered by embryonic stem cell assays? Arch. Toxicol. 85, 1361-1372.
    • (2011) Toxicol , vol.85 , pp. 1361-1372
    • Seiler, A.1    Oelgeschläger, M.2    Liebsch, M.3    Pirow, R.4    Riebeling, C.5    Tralau, T.6    Luch, A.7
  • 45
    • 77956395078 scopus 로고    scopus 로고
    • Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: Effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells
    • Slotkin, T. A., and Seidler, F. J. (2010). Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: Effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells. Brain Res. 1353, 36-52.
    • (2010) Brain Res , vol.1353 , pp. 36-52
    • Slotkin, T.A.1    Seidler, F.J.2
  • 47
    • 79955379993 scopus 로고    scopus 로고
    • Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures
    • Stiegler, N. V., Krug, A. K., Matt, F., and Leist, M. (2011). Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures. Toxicol. Sci. 121, 73-87.
    • (2011) Toxicol. Sci. , vol.121 , pp. 73-87
    • Stiegler, N.V.1    Krug, A.K.2    Matt, F.3    Leist, M.4
  • 48
    • 84864511648 scopus 로고    scopus 로고
    • Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts
    • van Thriel, C., Westerink, R. H., Beste, C., Bale, A. S., Lein, P. J., and Leist, M. (2012). Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts. Neurotoxicology 33, 911-924.
    • (2012) Neurotoxicology , vol.33 , pp. 911-924
    • van Thriel, C.1    Westerink, R.H.2    Beste, C.3    Bale, A.S.4    Lein, P.J.5    Leist, M.6
  • 49
    • 84055224146 scopus 로고    scopus 로고
    • Human embryonic stem cellderived neurons adopt and regulate the activity of an established neural network
    • Weick, J. P., Liu, Y., and Zhang, S. C. (2011). Human embryonic stem cellderived neurons adopt and regulate the activity of an established neural network. Proc. Natl. Acad. Sci. U.S.A. 108, 20189-20194.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 20189-20194
    • Weick, J.P.1    Liu, Y.2    Zhang, S.C.3
  • 50
    • 1442312201 scopus 로고    scopus 로고
    • Exocytosis: Using amperometry to study presynaptic mechanisms of neurotoxicity
    • Westerink, R. H. (2004). Exocytosis: Using amperometry to study presynaptic mechanisms of neurotoxicity. Neurotoxicology 25, 461-470.
    • (2004) Neurotoxicology , vol.25 , pp. 461-470
    • Westerink, R.H.1
  • 51
    • 80051592778 scopus 로고    scopus 로고
    • Developmental aspects of environmental neurotoxicology: Lessons from lead and polychlorinated biphenyls
    • Winneke, G. (2011). Developmental aspects of environmental neurotoxicology: Lessons from lead and polychlorinated biphenyls. J. Neurol. Sci. 308, 9-15.
    • (2011) J. Neurol. Sci. , vol.308 , pp. 9-15
    • Winneke, G.1
  • 52
    • 0346337290 scopus 로고    scopus 로고
    • Comparative study of membrane potential-sensitive fluorescent probes and their use in ion channel screening assays
    • Wolff, C., Fuks, B., and Chatelain, P. (2003). Comparative study of membrane potential-sensitive fluorescent probes and their use in ion channel screening assays. J. Biomol. Screen. 8, 533-543.
    • (2003) J. Biomol. Screen. , vol.8 , pp. 533-543
    • Wolff, C.1    Fuks, B.2    Chatelain, P.3
  • 53
    • 79951678616 scopus 로고    scopus 로고
    • Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing
    • Zimmer, B., Kuegler, P. B., Baudis, B., Genewsky, A., Tanavde, V., Koh, W., Tan, B., Waldmann, T., Kadereit, S., and Leist, M. (2011). Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing. Cell Death Differ. 18, 383-395.
    • (2011) Cell Death Differ , vol.18 , pp. 383-395
    • Zimmer, B.1    Kuegler, P.B.2    Baudis, B.3    Genewsky, A.4    Tanavde, V.5    Koh, W.6    Tan, B.7    Waldmann, T.8    Kadereit, S.9    Leist, M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.