Comparative study of membrane potential-sensitive fluorescent probes and their use in ion channel screening assays

Journal of Biomolecular Screening

Volumn 8, Issue 5, 2003, Pages 533-543

  Wolff, Christian ^a   Fuks, Bruno ^a   Chatelain, Pierre ^a  

^a UCB PHARMA   (Belgium)

Author keywords

Fluorescence; Fluorescence resonance energy transfer; High throughput screening; Membrane potential probes

Indexed keywords

BIS(1,3 DIBUTYLBARBITURIC ACID)TRIMETHINE OXONOL; CYANINE DYE; FLICE INHIBITORY PROTEIN; FLUORESCENT DYE; GRAMICIDIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; ION CHANNEL; OXONOL; POTASSIUM CHANNEL; UNCLASSIFIED DRUG; BARBITURIC ACID DERIVATIVE; BIS(1,3 DIHEXYL 2 THIOBARBITURATE)TRIMETHINEOXONOL; BIS(1,3-DIBUTYLBARBITURATE)TRIMETHINE OXONOL; BIS(1,3-DIHEXYL-2-THIOBARBITURATE)TRIMETHINEOXONOL; ISOXAZOLE DERIVATIVE; THIOBARBITURIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSAY; CELL MEMBRANE PERMEABILITY; COMPARATIVE STUDY; DEVICE; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; SCREENING; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CHEMISTRY; CHO CELL; DRUG EFFECT; DRUG INTERACTION; DRUG SCREENING; HAMSTER; IC 50; KINETICS; METABOLISM; METHODOLOGY; MOLECULAR BIOLOGY; RAT;

ANIMALS; BARBITURATES; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CHO CELLS; CRICETINAE; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; GRAMICIDIN; INHIBITORY CONCENTRATION 50; ION CHANNELS; ISOXAZOLES; KINETICS; MEMBRANE POTENTIALS; MOLECULAR BIOLOGY; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; THIOBARBITURATES;

EID: 0346337290     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057103257806     Document Type: Article

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