Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways

Cell Stem Cell

Volumn 11, Issue 2, 2012, Pages 195-206

  Westerterp, Marit ^a,b   Gourion Arsiquaud, Samuel ^c,d   Murphy, Andrew J ^a   Shih, Alan ^e   Cremers, Serge ^a   Levine, Ross L ^e   Tall, Alan R ^a   Yvan Charvet, Laurent ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

^d TRI PRINCETON   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; ATAXIN 1; CD31 ANTIGEN; CD45 ANTIGEN; CD51 ANTIGEN; CHOLESTEROL; CXCL2 CHEMOKINE; DIPEPTIDYL PEPTIDASE IV; GRANULOCYTE COLONY STIMULATING FACTOR; HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 3; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; NESTIN; OSTEOCALCIN; STROMAL CELL DERIVED FACTOR 1; VASCULAR CELL ADHESION MOLECULE 1; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL LINEAGE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DENDRITIC CELL; EXTRAMEDULLARY HEMATOPOIESIS; GRANULOCYTE; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; MACROPHAGE; MESENCHYMAL STEM CELL; MOUSE; MOUSE STRAIN; MYELOPROLIFERATIVE NEOPLASM; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REGULATORY MECHANISM; SPLENIC MACROPHAGE; STEM CELL MOBILIZATION;

ANIMALS; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL MOVEMENT; CHOLESTEROL; DISEASE MODELS, ANIMAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; LIPOPROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELOPROLIFERATIVE DISORDERS; STEM CELLS;

MUS;

EID: 84864582238     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2012.04.024     Document Type: Article

References (48)

1. A. Chow, D. Lucas, A. Hidalgo, S. Méndez-Ferrer, D. Hashimoto, C. Scheiermann, M. Battista, M. Leboeuf, C. Prophete, and N. van Rooijen Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche J. Exp. Med. 208 2011 261 271
2. M.J. Christopher, and D.C. Link Granulocyte colony-stimulating factor induces osteoblast apoptosis and inhibits osteoblast differentiation J. Bone Miner. Res. 23 2008 1765 1774
3. M.J. Christopher, F. Liu, M.J. Hilton, F. Long, and D.C. Link Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization Blood 114 2009 1331 1339
4. M.J. Christopher, M. Rao, F. Liu, J.R. Woloszynek, and D.C. Link Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice J. Exp. Med. 208 2011 251 260
5. A. Dar, P. Goichberg, V. Shinder, A. Kalinkovich, O. Kollet, N. Netzer, R. Margalit, M. Zsak, A. Nagler, and I. Hardan Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells Nat. Immunol. 6 2005 1038 1046 (Pubitemid 41486189)
6. S. Dessì, B. Batetta, O. Spano, F. Sanna, M. Tonello, M. Giacchino, L. Tessitore, P. Costelli, F.M. Baccino, and E. Madon Clinical remission is associated with restoration of normal high-density lipoprotein cholesterol levels in children with malignancies Clin. Sci. 89 1995 505 510
7. A. Ehninger, and A. Trumpp The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in J. Exp. Med. 208 2011 421 428
8. W.E. Fibbe, J.F. Pruijt, G.A. Velders, G. Opdenakker, Y. van Kooyk, C.G. Figdor, and R. Willemze Biology of IL-8-induced stem cell mobilization Ann. N Y Acad. Sci. 872 1999 71 82 (Pubitemid 29267848)
9. F. Fossiez, O. Djossou, P. Chomarat, L. Flores-Romo, S. Ait-Yahia, C. Maat, J.J. Pin, P. Garrone, E. Garcia, and S. Saeland T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines J. Exp. Med. 183 1996 2593 2603 (Pubitemid 26193037)
10. H.S. Gilbert, H. Ginsberg, R. Fagerstrom, and W.V. Brown Characterization of hypocholesterolemia in myeloproliferative disease. Relation to disease manifestations and activity Am. J. Med. 71 1981 595 602 (Pubitemid 12140427)
11. C. Gordy, H. Pua, G.D. Sempowski, and Y.W. He Regulation of steady-state neutrophil homeostasis by macrophages Blood 117 2011 618 629
12. S. Gourion-Arsiquaud, M.R. Allen, D.B. Burr, D. Vashishth, S.Y. Tang, and A.L. Boskey Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity Bone 46 2010 666 672
13. A.M. Greenbaum, and D.C. Link Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization Leukemia 25 2011 211 217
14. T. Guillaume, V. D'Hondt, and M. Symann IL-3 and peripheral blood stem cell harvesting Stem Cells 11 1993 173 181 (Pubitemid 23150935)
15. I.I. Ivanov, Rde.L. Frutos, N. Manel, K. Yoshinaga, D.B. Rifkin, R.B. Sartor, B.B. Finlay, and D.R. Littman Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine Cell Host Microbe 4 2008 337 349
16. S. Jaiswal, C.H. Jamieson, W.W. Pang, C.Y. Park, M.P. Chao, R. Majeti, D. Traver, N. van Rooijen, and I.L. Weissman CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis Cell 138 2009 271 285
17. L.M. Kelly, Q. Liu, J.L. Kutok, I.R. Williams, C.L. Boulton, and D.G. Gilliland FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model Blood 99 2002 310 318
18. M.J. Kiel, G.L. Radice, and S.J. Morrison Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance Cell Stem Cell 1 2007 204 217 (Pubitemid 47215590)
19. M.D. Kraus, N.L. Bartlett, M.D. Fleming, and D.M. Dorfman Splenic pathology in myelodysplasia: a report of 13 cases with clinical correlation Am. J. Surg. Pathol. 22 1998 1255 1266 (Pubitemid 28462774)
20. B.A. Laffitte, J.J. Repa, S.B. Joseph, D.C. Wilpitz, H.R. Kast, D.J. Mangelsdorf, and P. Tontonoz LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes Proc. Natl. Acad. Sci. USA 98 2001 507 512 (Pubitemid 32105072)
21. J.P. Lévesque, J. Hendy, Y. Takamatsu, B. Williams, I.G. Winkler, and P.J. Simmons Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment Exp. Hematol. 30 2002 440 449 (Pubitemid 34556735)
22. J.P. Levesque, J. Hendy, Y. Takamatsu, P.J. Simmons, and L.J. Bendall Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide J. Clin. Invest. 111 2003 187 196 (Pubitemid 36105917)
23. J.P. Levesque, F. Liu, P.J. Simmons, T. Betsuyaku, R.M. Senior, C. Pham, and D.C. Link Characterization of hematopoietic progenitor mobilization in protease-deficient mice Blood 104 2004 65 72 (Pubitemid 38879839)
24. K. Liu, and M.C. Nussenzweig Origin and development of dendritic cells Immunol. Rev. 234 2010 45 54
25. F. Liu, J. Poursine-Laurent, and D.C. Link Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF Blood 95 2000 3025 3031 (Pubitemid 30321150)
26. S. Lymperi, N. Horwood, S. Marley, M.Y. Gordon, A.P. Cope, and F. Dazzi Strontium can increase some osteoblasts without increasing hematopoietic stem cells Blood 111 2008 1173 1181 (Pubitemid 351213398)
27. S. Lymperi, F. Ferraro, and D.T. Scadden The HSC niche concept has turned 31. Has our knowledge matured? Ann. N Y Acad. Sci. 1192 2010 12 18
28. S. Méndez-Ferrer, T.V. Michurina, F. Ferraro, A.R. Mazloom, B.D. Macarthur, S.A. Lira, D.T. Scadden, A. Ma'ayan, G.N. Enikolopov, and P.S. Frenette Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Nature 466 2010 829 834
29. D. Metcalf Hematopoietic cytokines Blood 111 2008 485 491
30. S.J. Morrison, D.E. Wright, and I.L. Weissman Cyclophosphamide/ granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization Proc. Natl. Acad. Sci. USA 94 1997 1908 1913 (Pubitemid 27113935)
31. A.J. Murphy, M. Akhtari, S. Tolani, T. Pagler, N. Bijl, C.L. Kuo, M. Wang, M. Sanson, S. Abramowicz, and C. Welch ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice J. Clin. Invest. 121 2011 4138 4149
32. D.P. O'Malley, Y.S. Kim, S.L. Perkins, L. Baldridge, B.E. Juliar, and A. Orazi Morphologic and immunohistochemical evaluation of splenic hematopoietic proliferations in neoplastic and benign disorders Mod. Pathol. 18 2005 1550 1561 (Pubitemid 41670653)
33. J.M. Perry, and L. Li Disrupting the stem cell niche: good seeds in bad soil Cell 129 2007 1045 1047 (Pubitemid 46891049)
34. I. Petit, M. Szyper-Kravitz, A. Nagler, M. Lahav, A. Peled, L. Habler, T. Ponomaryov, R.S. Taichman, F. Arenzana-Seisdedos, and N. Fujii G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4 Nat. Immunol. 3 2002 687 694 (Pubitemid 34752479)
35. M.H. Raaijmakers, S. Mukherjee, S. Guo, S. Zhang, T. Kobayashi, J.A. Schoonmaker, B.L. Ebert, F. Al-Shahrour, R.P. Hasserjian, and E.O. Scadden Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia Nature 464 2010 852 857
36. M.A. Rieger, P.S. Hoppe, B.M. Smejkal, A.C. Eitelhuber, and T. Schroeder Hematopoietic cytokines can instruct lineage choice Science 325 2009 217 218
37. C.S. Robbins, A. Chudnovskiy, P.J. Rauch, J.L. Figueiredo, Y. Iwamoto, R. Gorbatov, M. Etzrodt, G.F. Weber, T. Ueno, and N. van Rooijen Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions Circulation 25 2012 364 374
38. C.L. Semerad, M.J. Christopher, F. Liu, B. Short, P.J. Simmons, I. Winkler, J.P. Levesque, J. Chappel, F.P. Ross, and D.C. Link G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow Blood 106 2005 3020 3027 (Pubitemid 41565894)
39. M.A. Stark, Y. Huo, T.L. Burcin, M.A. Morris, T.S. Olson, and K. Ley Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17 Immunity 22 2005 285 294 (Pubitemid 40387471)
40. T. Sugiyama, H. Kohara, M. Noda, and T. Nagasawa Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches Immunity 25 2006 977 988 (Pubitemid 44894948)
41. D. Visnjic, Z. Kalajzic, D.W. Rowe, V. Katavic, J. Lorenzo, and H.L. Aguila Hematopoiesis is severely altered in mice with an induced osteoblast deficiency Blood 103 2004 3258 3264 (Pubitemid 38525648)
42. X. Wang, H.L. Collins, M. Ranalletta, I.V. Fuki, J.T. Billheimer, G.H. Rothblat, A.R. Tall, and D.J. Rader Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo J. Clin. Invest. 117 2007 2216 2224 (Pubitemid 47219566)
43. I.G. Winkler, N.A. Sims, A.R. Pettit, V. Barbier, B. Nowlan, F. Helwani, I.J. Poulton, N. van Rooijen, K.A. Alexander, L.J. Raggatt, and J.P. Lévesque Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs Blood 116 2010 4815 4828
44. L. Yvan-Charvet, M. Ranalletta, N. Wang, S. Han, N. Terasaka, R. Li, C. Welch, and A.R. Tall Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice J. Clin. Invest. 117 2007 3900 3908 (Pubitemid 350224099)
45. L. Yvan-Charvet, C. Welch, T.A. Pagler, M. Ranalletta, M. Lamkanfi, S. Han, M. Ishibashi, R. Li, N. Wang, and A.R. Tall Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions Circulation 118 2008 1837 1847
46. L. Yvan-Charvet, T. Pagler, E.L. Gautier, S. Avagyan, R.L. Siry, S. Han, C.L. Welch, N. Wang, G.J. Randolph, H.W. Snoeck, and A.R. Tall ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation Science 328 2010 1689 1693
47. J. Zhang, C. Niu, L. Ye, H. Huang, X. He, W.G. Tong, J. Ross, J. Haug, T. Johnson, and J.Q. Feng Identification of the haematopoietic stem cell niche and control of the niche size Nature 425 2003 836 841 (Pubitemid 37351467)
48. J. Zhu, and S.G. Emerson Hematopoietic cytokines, transcription factors and lineage commitment Oncogene 21 2002 3295 3313 (Pubitemid 34587705)