AEG-1 overexpression is essential for maintenance of malignant state in human AML cells via up-regulation of Akt1 mediated by AURKA activation

Cellular Signalling

Volumn 25, Issue 6, 2013, Pages 1438-1446

  Long, Min ^a   Hao, Miaowang ^b   Dong, Ke ^a   Shen, Jianjun ^a   Wang, Xi ^a   Lin, Fang ^a   Liu, Li ^a   Wei, Junxia ^a   Liang, Yingmin ^b   Yang, Jian ^b   Gu, Fangna ^b   Zhang, Huizhong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

AEG 1; Akt1; AML; AURKA

Indexed keywords

AURORA A KINASE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN AKT308; PROTEIN AKT473; PROTEIN KINASE B; SHORT HAIRPIN RNA; STATHMIN; SURVIVIN; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; AKT1 GENE; APOPTOSIS; ARTICLE; ASTROCYTE ELEVATED GENE 1; AURORA KINASE A GENE; CANCER RESISTANCE; CELL CYCLE; CELL PROLIFERATION; CELL STRAIN; CELL STRAIN ECV304; CELL STRAIN HL 60; CELL STRAIN U937; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; GENE; GENE CONTROL; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA CELL; MALE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; UPREGULATION;

ANTINEOPLASTIC AGENTS; CELL ADHESION MOLECULES; CELL SURVIVAL; CENTROSOME; CISPLATIN; DOWN-REGULATION; HL-60 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LEUKEMIA, MYELOID, ACUTE; PHENOTYPE; PHOSPHORYLATION; PIPERAZINES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; STATHMIN; U937 CELLS; UP-REGULATION;

EID: 84876335845     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.03.001     Document Type: Article

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