Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype

Basic Research in Cardiology

Volumn 106, Issue 2, 2011, Pages 205-215

  Kohlstedt, Karin ^a   Trouvain, Caroline ^a   Namgaladze, Dmitry ^a   Fleming, Ingrid ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Adipose tissue derived lipids; AMPK; Angiotensin converting enzyme; Inflammation; Macrophage polarization

Indexed keywords

CYCLOOXYGENASE 2; DIPEPTIDYL CARBOXYPEPTIDASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA1; INTERLEUKIN 6; LIPID; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL TYPE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOMODULATION; MACROPHAGE; MACROPHAGE ACTIVATION; MOLECULAR MIMICRY; MONOCYTE; MOUSE; NONHUMAN; POLARIZATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPLEEN; UPREGULATION; ADIPOSE TISSUE; ANIMAL; CELL CULTURE; CELL LINE; CYTOLOGY; LIPID METABOLISM; METABOLISM; PHENOTYPE; TRANSGENIC MOUSE;

ADIPOSE TISSUE; ANIMALS; CELL LINE; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; HUMANS; LIPID METABOLISM; MACROPHAGES; MICE; MICE, TRANSGENIC; MONOCYTES; PEPTIDYL-DIPEPTIDASE A; PHENOTYPE; SIGNAL TRANSDUCTION;

EID: 79957815398     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-010-0137-9     Document Type: Article

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