Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques

British Journal of Pharmacology

Volumn 162, Issue 6, 2011, Pages 1410-1423

  De Meyer, Inge ^a   Martinet, Wim ^a   Van Hove, Cor E ^a   Schrijvers, Dorien M ^a   Hoymans, Vicky Y ^b   Van Vaeck, Luc ^a   Fransen, Paul ^a   Bult, Hidde ^a   De Meyer, Guido R Y ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

apoptosis; atherosclerosis; inositol monophosphatase; lithium; macrophage; plaque stability

Indexed keywords

CASPASE 3; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL MONOPHOSPHATASE; LITHIUM CHLORIDE; PHOSPHATASE; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAROTID ATHEROSCLEROSIS; CELL FUNCTION; CELL LEVEL; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME INHIBITION; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RABBIT; SMOOTH MUSCLE FIBER; VASOMOTOR REFLEX;

ANIMALS; AORTA; APOPTOSIS; CAROTID ARTERIES; CELL SURVIVAL; ENZYME INHIBITORS; GENE SILENCING; GLYCOGEN SYNTHASE KINASE 3; LITHIUM CHLORIDE; MACROPHAGES; MICE; MYOCYTES, SMOOTH MUSCLE; PHOSPHORIC MONOESTER HYDROLASES; PLAQUE, ATHEROSCLEROTIC; RABBITS;

EID: 79951976090     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01152.x     Document Type: Article

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