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Volumn 29, Issue 6, 2013, Pages 2101-2108

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis and cell cycle arrest in CNE-2Z nasopharyngeal carcinoma cells

Author keywords

Cisplatin; Ent 11 hydroxy 15 oxo kaur 16 en 19 oic acid; Naso pharyngeal carcinoma; NF B; p53

Indexed keywords

CISPLATIN; CYTOCHROME C; ENT 11ALPHA HYDROXY 15 OXO KAUR 16 EN 19 OIC ACID; I KAPPA B KINASE; PLANT MEDICINAL PRODUCT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

EID: 84876213547     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2375     Document Type: Article
Times cited : (10)

References (47)
  • 3
    • 84863670779 scopus 로고    scopus 로고
    • Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibits the growth of human lung cancer A549 cells by arresting cell cycle and triggering apoptosis
    • Li L, Chen GG, Lu YN, Liu Y, Wu KF, Gong XL, Gou ZP, Li MY and Liang NC: Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibits the growth of human lung cancer A549 cells by arresting cell cycle and triggering apoptosis. Chin J Cancer Res 24: 109-115, 2012.
    • (2012) Chin J Cancer Res , vol.24 , pp. 109-115
    • Li, L.1    Chen, G.G.2    Lu, Y.N.3    Liu, Y.4    Wu, K.F.5    Gong, X.L.6    Gou, Z.P.7    Li, M.Y.8    Liang, N.C.9
  • 5
    • 30944462973 scopus 로고    scopus 로고
    • Cell death induced by ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid in anaplastic thyroid carcinoma cells is via a mitochondrial-mediated pathway
    • DOI 10.1007/s10495-005-1730-5
    • Liu ZM, Chen GG, Vlantis AC, Liang NC, Deng YF and van Hasselt CA: Cell death induced by ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid in anaplastic thyroid carcinoma cells is via a mitochondrial-mediated pathway. Apoptosis 10: 1345-1356, 2005. (Pubitemid 43117680)
    • (2005) Apoptosis , vol.10 , Issue.6 , pp. 1345-1356
    • Liu, Z.M.1    Chen, G.G.2    Vlantis, A.C.3    Liang, N.-C.4    Deng, Y.-F.5    Van Hasselt, C.A.6
  • 6
    • 14244251044 scopus 로고    scopus 로고
    • Cell death induced by Pteris semipinnata L. is associated with p53 and oxidant stress in gastric cancer cells
    • DOI 10.1016/j.febslet.2005.01.050
    • Liu Z, Ng EK, Liang NC, Deng YF, Leung BC and Chen GG: Cell death induced by Pteris semipinnata L. is associated with p53 and oxidant stress in gastric cancer cells. FEBS Lett 579: 1477-1487, 2005. (Pubitemid 40289199)
    • (2005) FEBS Letters , vol.579 , Issue.6 , pp. 1477-1487
    • Liu, Z.1    Ng, E.K.W.2    Liang, N.-C.3    Deng, Y.-F.4    Leung, B.C.S.5    Chen, G.G.6
  • 7
    • 4344632897 scopus 로고    scopus 로고
    • Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B - Related pathway
    • DOI 10.1023/B:APPT.0000038041.57782.84
    • Chen GG, Liang NC, Lee JF, Chan UP, Wang SH, Leung BC and Leung KL: Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B-related pathway. Apoptosis 9: 619-627, 2004. (Pubitemid 39158638)
    • (2004) Apoptosis , vol.9 , Issue.5 , pp. 619-627
    • Chen, G.G.1    Liang, N.-C.2    Lee, J.F.Y.3    Chan, U.P.F.4    Wang, S.H.5    Leung, B.C.S.6    Leung, K.L.7
  • 8
    • 0000598266 scopus 로고
    • New human nasopharyngeal epithelial cell line estab lished from a patient with poorly differentiated nasopharyngeal carcinoma
    • Gu SY, Zhao WP, Zeng Y, Tang WP, Zhao ML, Deng HH and Li K: New human nasopharyngeal epithelial cell line estab lished from a patient with poorly differentiated nasopharyngeal carcinoma. Chin J Cancer 2: 70-72, 1983.
    • (1983) Chin J Cancer , vol.2 , pp. 70-72
    • Gu, S.Y.1    Zhao, W.P.2    Zeng, Y.3    Tang, W.P.4    Zhao, M.L.5    Deng, H.H.6    Li, K.7
  • 9
    • 11144315983 scopus 로고    scopus 로고
    • Study on extraction and separation of diterpenoids from Pteris semipinnata
    • Deng YF and Liang NC: Study on extraction and separation of diterpenoids from Pteris semipinnata. Chin Pharm J 39: 742-744, 2004.
    • (2004) Chin Pharm J , vol.39 , pp. 742-744
    • Deng, Y.F.1    Liang, N.C.2
  • 10
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ: Cancer cell cycles. Science 274: 1672-1677, 1996.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 11
    • 0029317904 scopus 로고
    • Cyclin-dependent protein kinases: Key regulators of the eukaryotic cell cycle
    • Nigg EA: Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays 17: 471-480, 1995.
    • (1995) Bioessays , vol.17 , pp. 471-480
    • Nigg, E.A.1
  • 12
    • 0025936510 scopus 로고
    • cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
    • Gautier J, Solomon MJ, Booher RN, Bazan JF and Kirschner MW: cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell 67: 197-211, 1991.
    • (1991) Cell , vol.67 , pp. 197-211
    • Gautier, J.1    Solomon, M.J.2    Booher, R.N.3    Bazan, J.F.4    Kirschner, M.W.5
  • 13
    • 33947390474 scopus 로고    scopus 로고
    • Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity
    • Jiang M, Wei Q, Pabla N, Dong G, Wang CY, Yang T, Smith SB and Dong Z: Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity. Biochem Pharmacol 73: 1499-1510, 2007.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1499-1510
    • Jiang, M.1    Wei, Q.2    Pabla, N.3    Dong, G.4    Wang, C.Y.5    Yang, T.6    Smith, S.B.7    Dong, Z.8
  • 16
    • 33947202249 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in development, prevention, and therapy of cancer
    • Van Waes C: Nuclear factor-kappaB in development, prevention, and therapy of cancer. Clin Cancer Res 13: 1076-1082, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 1076-1082
    • Van Waes, C.1
  • 17
    • 7744235176 scopus 로고    scopus 로고
    • Targeting cell cycle and apoptosis for the treatment of human malignancies
    • Senderowicz AM: Targeting cell cycle and apoptosis for the treatment of human malignancies. Curr Opin Cell Biol 16: 670-678, 2004.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 670-678
    • Senderowicz, A.M.1
  • 18
    • 23944498904 scopus 로고    scopus 로고
    • 2 and early M phases and increased survival to microtubule-interacting agents
    • DOI 10.1124/mol.105.013995
    • Skladanowski A, Côme MG, Sabisz M, Escargueil AE and Larsen AK: Down-regulation of DNA topoisomerase IIalpha leads to prolonged cell cycle transit in G2 and early M phases and increased survival to microtubule- interacting agents. Mol Pharmacol 68: 625-634, 2005. (Pubitemid 41206016)
    • (2005) Molecular Pharmacology , vol.68 , Issue.3 , pp. 625-634
    • Skladanowski, A.1    Come, M.-G.2    Sabisz, M.3    Escargueil, A.E.4    Larsen, A.K.5
  • 21
    • 79959618716 scopus 로고    scopus 로고
    • Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance
    • Kalimutho M, Minutolo A, Grelli S, Formosa A, Sancesario G, Valentini A, Federici G and Bernardini S: Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance. Cancer Chemother Pharmacol 67: 1299-1312, 2011.
    • (2011) Cancer Chemother Pharmacol , vol.67 , pp. 1299-1312
    • Kalimutho, M.1    Minutolo, A.2    Grelli, S.3    Formosa, A.4    Sancesario, G.5    Valentini, A.6    Federici, G.7    Bernardini, S.8
  • 22
    • 79952327221 scopus 로고    scopus 로고
    • Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways
    • Huang WW, Ko SW, Tsai HY, Chung JG, Chiang JH, Chen KT, Chen YC, Chen HY, Chen YF and Yang JS: Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways. Int J Oncol 38: 1067-1073, 2011.
    • (2011) Int J Oncol , vol.38 , pp. 1067-1073
    • Huang, W.W.1    Ko, S.W.2    Tsai, H.Y.3    Chung, J.G.4    Chiang, J.H.5    Chen, K.T.6    Chen, Y.C.7    Chen, H.Y.8    Chen, Y.F.9    Yang, J.S.10
  • 23
    • 77953622693 scopus 로고    scopus 로고
    • Lunasin promotes apoptosis in human colon cancer cells by mitochondrial pathway activation and induction of nuclear clusterin expression
    • Dia VP and Mejia EG: Lunasin promotes apoptosis in human colon cancer cells by mitochondrial pathway activation and induction of nuclear clusterin expression. Cancer Lett 295: 44-53, 2010.
    • (2010) Cancer Lett , vol.295 , pp. 44-53
    • Dia, V.P.1    Mejia, E.G.2
  • 24
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: Intricate networks and multiple activities
    • Abbas T and Dutta A: p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 9: 400-414, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 25
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: The growing complexity of p53
    • Vousden KH and Prives C: Blinded by the light: the growing complexity of p53. Cell 137: 413-431, 2009.
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 26
    • 0028009789 scopus 로고
    • Cellular responses to cisplatin: The roles of DNA-binding proteins and DNA repair
    • Chu G: Cellular responses to cisplatin: The roles of DNA-binding proteins and DNA repair. J Biol Chem 269: 787-790, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 787-790
    • Chu, G.1
  • 27
    • 33745782940 scopus 로고    scopus 로고
    • HPMA copolymer-bound doxorubicin induces apoptosis in ovarian carcinoma cells by the disruption of mitochondrial function
    • DOI 10.1021/mp050065e
    • Malugin A, Kopecková P and Kopecek J: HPMA copolymer-bound doxorubicin induces apoptosis in ovarian carcinoma cells by the disruption of mitochondrial function. Mol Pharm 3: 351-361, 2006. (Pubitemid 44021441)
    • (2006) Molecular Pharmaceutics , vol.3 , Issue.3 , pp. 351-361
    • Malugin, A.1    Kopeckova, P.2    Kopecek, J.3
  • 28
    • 9644302485 scopus 로고    scopus 로고
    • Proteomic analysis of antiproliferative effects by treatment of 5-fluorouracil in cervical cancer cells
    • Yim EK, Lee KH, Bae JS, Namkoong SE, Um SJ and Park JS: Proteomic analysis of antiproliferative effects by treatment of 5-fluorouracil in cervical cancer cells. DNA Cell Biol 23: 769-776, 2004.
    • (2004) DNA Cell Biol , vol.23 , pp. 769-776
    • Yim, E.K.1    Lee, K.H.2    Bae, J.S.3    Namkoong, S.E.4    Um, S.J.5    Park, J.S.6
  • 29
    • 2142694056 scopus 로고    scopus 로고
    • Cisplatin and platinum drugs at the molecular level
    • Review
    • Boulikas T and Vougiouka M: Cisplatin and platinum drugs at the molecular level (Review). Oncol Rep 10: 1663-1682, 2003.
    • (2003) Oncol Rep , vol.10 , pp. 1663-1682
    • Boulikas, T.1    Vougiouka, M.2
  • 30
    • 31144440676 scopus 로고    scopus 로고
    • Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line
    • Lin JP, Yang JS, Lee JH, Hsieh WT and Chung JG: Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line. World J Gastroenterol 12: 21-28, 2006.
    • (2006) World J Gastroenterol , vol.12 , pp. 21-28
    • Lin, J.P.1    Yang, J.S.2    Lee, J.H.3    Hsieh, W.T.4    Chung, J.G.5
  • 31
    • 31144436796 scopus 로고    scopus 로고
    • Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells
    • Hwang JM, Kuo HC, Tseng TH, Liu JY and Chu CY: Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells. Arch Toxicol 80: 62-73, 2006.
    • (2006) Arch Toxicol , vol.80 , pp. 62-73
    • Hwang, J.M.1    Kuo, H.C.2    Tseng, T.H.3    Liu, J.Y.4    Chu, C.Y.5
  • 32
    • 33644984254 scopus 로고    scopus 로고
    • Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells
    • Mantena SK, Sharma SD and Katiyar SK: Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mol Cancer Ther 5: 296-308, 2006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 296-308
    • Mantena, S.K.1    Sharma, S.D.2    Katiyar, S.K.3
  • 33
    • 0028814733 scopus 로고
    • Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells
    • Kuo CL, Chou CC and Yung BY: Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells. Cancer Lett 93: 193-200, 1995.
    • (1995) Cancer Lett , vol.93 , pp. 193-200
    • Kuo, C.L.1    Chou, C.C.2    Yung, B.Y.3
  • 34
    • 0033593572 scopus 로고    scopus 로고
    • Cell death in development
    • DOI 10.1016/S0092-8674(00)80564-4
    • Vaux DL and Korsmeyer SJ: Cell death in development. Cell 96: 245-254, 1999. (Pubitemid 29059354)
    • (1999) Cell , vol.96 , Issue.2 , pp. 245-254
    • Vaux, D.L.1    Korsmeyer, S.J.2
  • 35
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: The enemy within
    • Aggarwal BB: Nuclear factor-kappaB: the enemy within. Cancer Cell 6: 203-208, 2004.
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.B.1
  • 36
    • 84859590530 scopus 로고    scopus 로고
    • Id-1 and the p65 subunit of NF-κB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis
    • Sun W, Guo MM, Han P, Lin JZ, Liang FY, Tan GM, Li HB, Zeng M and Huang XM: Id-1 and the p65 subunit of NF-κB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis. Carcinogenesis 33: 810-817, 2012.
    • (2012) Carcinogenesis , vol.33 , pp. 810-817
    • Sun, W.1    Guo, M.M.2    Han, P.3    Lin, J.Z.4    Liang, F.Y.5    Tan, G.M.6    Li, H.B.7    Zeng, M.8    Huang, X.M.9
  • 38
    • 1942532874 scopus 로고    scopus 로고
    • Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappaB and induction of apoptosis
    • DOI 10.1038/sj.onc.1207353
    • Gupta S, Hastak K, Afaq F, Ahmad N and Mukhtar H: Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis. Oncogene 23: 2507-2522, 2004. (Pubitemid 38520748)
    • (2004) Oncogene , vol.23 , Issue.14 , pp. 2507-2522
    • Gupta, S.1    Hastak, K.2    Afaq, F.3    Ahmad, N.4    Mukhtar, H.5
  • 39
    • 0031011174 scopus 로고    scopus 로고
    • Role of reactive oxygen species in cis-dichlorodiammineplatinum-induced cytotoxicity on bladder cancer cells
    • Miyajima A, Nakashima J, Yoshioka K, Tachibana M, Tazaki H and Murai M: Role of reactive oxygen species in cis-dichlorodiammineplatinum-induced cytotoxicity on bladder cancer cells. Br J Cancer 76: 206-210, 1997. (Pubitemid 27279660)
    • (1997) British Journal of Cancer , vol.76 , Issue.2 , pp. 206-210
    • Miyajima, A.1    Nakashima, J.2    Yoshioka, K.3    Tachibana, M.4    Tazaki, H.5    Murai, M.6
  • 40
    • 0023258905 scopus 로고
    • Role of free radicals in an adriamycin-resistant human small cell lung cancer cell line
    • Meijer C, Mulder NH, Timmer-Bosscha H, Zijlstra JG and de Vries EG: Role of free radicals in an adriamycin-resistant human small cell lung cancer cell line. Cancer Res 47: 4613- 4617, 1987.
    • (1987) Cancer Res , vol.47 , pp. 4613-4617
    • Meijer, C.1    Mulder, N.H.2    Timmer-Bosscha, H.3    Zijlstra, J.G.4    De Vries, E.G.5
  • 41
    • 0018149642 scopus 로고
    • Properties and products of the degradation of DNA by bleomycin and iron (II)
    • Sausville EA, Stein RW, Peisach J and Horwitz SB: Properties and products of the degradation of DNA by bleomycin and iron (II). Biochemistry 17: 2746-2754, 1978. (Pubitemid 8385273)
    • (1978) Biochemistry , vol.17 , Issue.14 , pp. 2746-2754
    • Sausville, E.A.1    Stein, R.W.2    Peisach, J.3    Horwitz, S.B.4
  • 42
    • 0024542266 scopus 로고
    • Intracellular hydroxyl radical production induced by recombinant human tumor necrosis factor and its implication in the killing of tumor cells in vitro
    • Yamauchi N, Kuriyama H, Watanabe N, Neda H, Maeda M and Niitsu Y: Intracellular hydroxyl radical production induced by recombinant human tumor necrosis factor and its implication in the killing of tumor cells in vitro. Cancer Res 49: 1671-1675, 1989. (Pubitemid 19108385)
    • (1989) Cancer Research , vol.49 , Issue.7 , pp. 1671-1675
    • Yamauchi, N.1    Kuriyama, H.2    Watanabe, N.3    Neda, H.4    Maeda, M.5    Niitsu, Y.6
  • 43
    • 67349112401 scopus 로고    scopus 로고
    • Role of oxidative and nitro sative stress in cisplatin-induced nephrotoxicity
    • Chirino YI and Pedraza-Chaverri J: Role of oxidative and nitro sative stress in cisplatin-induced nephrotoxicity. Exp Toxicol Pathol 61: 223-242, 2009.
    • (2009) Exp Toxicol Pathol , vol.61 , pp. 223-242
    • Chirino, Y.I.1    Pedraza-Chaverri, J.2
  • 44
    • 33947212468 scopus 로고    scopus 로고
    • Mechanisms of cisplatin-induced ototoxicity and prevention
    • DOI 10.1016/j.heares.2006.09.015, PII S0378595506002723, Pharmacological Strategies for Prevention and Treatment of Hearing Loss and Tinnitus
    • Rybak LP, Whitworth CA, Mukherjea D and Ramkumar V: Mechanisms of cisplatin-induced ototoxicity and prevention. Hear Res 226: 157-167, 2007. (Pubitemid 46428033)
    • (2007) Hearing Research , vol.226 , Issue.1-2 , pp. 157-167
    • Rybak, L.P.1    Whitworth, C.A.2    Mukherjea, D.3    Ramkumar, V.4
  • 45
    • 33746007179 scopus 로고    scopus 로고
    • Future opportunities in preventing cisplatin induced ototoxicity
    • DOI 10.1016/j.ctrv.2006.04.011, PII S0305737206000971
    • van den Berg JH, Beijnen JH, Balm AJ and Schellens JH: Future opportunities in preventing cisplatin induced ototoxicity. Cancer Treat Rev 32: 390-397, 2006. (Pubitemid 44063878)
    • (2006) Cancer Treatment Reviews , vol.32 , Issue.5 , pp. 390-397
    • Van Den, B.J.H.1    Beijnen, J.H.2    Balm, A.J.M.3    Schellens, J.H.M.4


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