Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

BMC Genomics

Volumn 14, Issue 1, 2013, Pages

  Tanisawa, Kumpei ^a,b   Mikami, Eri ^a,b,c   Fuku, Noriyuki ^a   Honda, Yoko ^a   Honda, Shuji ^a   Ohsawa, Ikuro ^a   Ito, Masafumi ^a   Endo, Shogo ^a   Ihara, Kunio ^d   Ohno, Kinji ^e   Kishimoto, Yuki ^a   Ishigami, Akihito ^a   Maruyama, Naoki ^a   Sawabe, Motoji ^a   Iseki, Hiroyoshi ^f   Okazaki, Yasushi ^f   Hasegawa Ishii, Sanae ^g   Takei, Shiro ^g   Shimada, Atsuyoshi ^g   Hosokawa, Masanori ^g   Mori, Masayuki ^h   Higuchi, Keiichi ^h   Takeda, Toshio ⁱ   Higuchi, Mitsuru ^b   Tanaka, Masashi ^a   more..

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

^e NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f SAITAMA MEDICAL UNIVERSITY   (Japan)

^g INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^h SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

ⁱ Council for SAM Research ^*  (Japan)

Author keywords

Aging; Exome sequencing; Senescence accelerated mice

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; EXOME; GENETIC ASSOCIATION; GENETIC VARIABILITY; LDB3 GENE; MBD4 GENE; MISSENSE MUTATION; MOUSE; MOUSE STRAIN; MUTATIONAL ANALYSIS; MUTATOR GENE; NONHUMAN; OGG1 GENE; PRX GENE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS;

AGING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DISEASE; EXOME; EXONS; GENOMICS; HUMANS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; SEQUENCE ANALYSIS; SPECIES SPECIFICITY;

MUS;

EID: 84876143284     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-14-248     Document Type: Article

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