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Volumn 49, Issue 36, 2013, Pages 3775-3777

Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A

(4) De Vreese, Rob a Verhaeghe, Tom a Desmet, Tom a D’hooghe, Matthias a

a GHENT UNIVERSITY (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

6 (1,3 DIOXO 1H,3H BENZO[DE]ISOQUINOLIN 2 YL) N HYDROXYHEXANAMIDE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 11; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 6 INHIBITOR; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; N (4 HYDROXYCARBAMOYLBENZYL) 1,2,4,9 TETRAHYDRO 3 THIA 9 AZAFLUORENE; SULFIDE; SULFONE; SULFONE DERIVATIVE; SULFUR DERIVATIVE; TRICHOSTATIN A; TUBACIN; TUBASTATIN A; UNCLASSIFIED DRUG;

ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; DEGENERATIVE DISEASE; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IC 50; UNSPECIFIED SIDE EFFECT;

EID: 84876123648 PISSN: 13597345 EISSN: 1364548X Source Type: Journal
DOI: 10.1039/c3cc41422a Document Type: Article

Times cited : (34)

References (29)

1
- 36048958965
- M. Dokmanovic, C. Clarke, P. A. Marks, Mol. Cancer Res., 2007, 5, 981
- (2007) Mol. Cancer Res. , vol.5 , pp. 981
- Dokmanovic, M.¹ Clarke, C.² Marks, P.A.³

2
- 78649905409
- P. A. Marks, Biochim. Biophys. Acta, Gene Regul. Mech., 2010, 1799, 717
- (2010) Biochim. Biophys. Acta, Gene Regul. Mech. , vol.1799 , pp. 717
- Marks, P.A.¹

3
- 79952932076
- H. J. Kim, S. C. Bae, Am. J. Transl. Res., 2011, 3, 166
- (2011) Am. J. Transl. Res. , vol.3 , pp. 166
- Kim, H.J.¹ Bae, S.C.²

4
- 33748451151
- J. E. Bolden, M. J. Peart, R. W. Johnstone, Nat. Rev. Drug Discovery, 2006, 5, 769
- (2006) Nat. Rev. Drug Discovery , vol.5 , pp. 769
- Bolden, J.E.¹ Peart, M.J.² Johnstone, R.W.³

5
- 79951713773
- L. D. Marcotullio, G. Canettieri, P. Infante, A. Greco, A. Gulino, Biochim. Biophys. Acta, 2011, 1815, 241
- (2011) Biochim. Biophys. Acta , vol.1815 , pp. 241
- Marcotullio, L.D.¹ Canettieri, G.² Infante, P.³ Greco, A.⁴ Gulino, A.⁵

6
- 79957939679
- N. A. Shein, E. Shohami, Mol. Med., 2011, 17, 448
- (2011) Mol. Med. , vol.17 , pp. 448
- Shein, N.A.¹ Shohami, E.²

7
- 53249130741
- A. G. Kazantsev, M. L. Thompson, Nat. Rev. Drug Discovery, 2008, 7, 854
- (2008) Nat. Rev. Drug Discovery , vol.7 , pp. 854
- Kazantsev, A.G.¹ Thompson, M.L.²

8
- 0037444803
- A. J. M. De Ruijter, A. H. Van Gennip, H. N. Caron, S. Kemp, A. B. P. Van Kuilenburg, Biochem. J., 2003, 370, 737
- (2003) Biochem. J. , vol.370 , pp. 737
- De Ruijter, A.J.M.¹ Van Gennip, A.H.² Caron, H.N.³ Kemp, S.⁴ Van Kuilenburg, A.B.P.⁵

9
- 33845514708
- T. C. Karagiannis, A. El-Osta, Leukemia, 2007, 21, 61
- (2007) Leukemia , vol.21 , pp. 61
- Karagiannis, T.C.¹ El-Osta, A.²

10
- 79953127793
- F. Thaler, S. Minucci, Expert Opin. Drug Discovery, 2011, 6, 393
- (2011) Expert Opin. Drug Discovery , vol.6 , pp. 393
- Thaler, F.¹ Minucci, S.²

11
- 84860915669
- C. d'Ydewalle, E. Bogaert, L. Van Den Bosch, Traffic, 2012, 13, 771
- (2012) Traffic , vol.13 , pp. 771
- D'ydewalle, C.¹ Bogaert, E.² Van Den Bosch, L.³

12
- 79953311481
- G. Li, H. Jiang, M. Chang, H. Xie, L. Hu, J. Neurol. Sci., 2011, 304, 1
- (2011) J. Neurol. Sci. , vol.304 , pp. 1
- Li, G.¹ Jiang, H.² Chang, M.³ Xie, H.⁴ Hu, L.⁵

13
- 85007546403
- G. I. Aldana-Masangkay, K. M. Sakamoto, J. Biomed. Biotechnol., 2011, 1
- (2011) J. Biomed. Biotechnol. , pp. 1
- Aldana-Masangkay, G.I.¹ Sakamoto, K.M.²

14
- 44649158252
- A. Valenzuela-Fernández, J. R. Cabrero, J. M. Serrador, F. Sánchez-Madrid, Trends Cell Biol., 2008, 18, 291
- (2008) Trends Cell Biol. , vol.18 , pp. 291
- Valenzuela-Fern, A.¹ Ándezcabrero, J.R.² Serrador, J.M.³ Sánchez-Madrid, F.⁴

15
- 34547684065
- C. Boyault, K. Sadoul, M. Pabion, S. Khochbin, Oncogene, 2007, 26, 5468
- (2007) Oncogene , vol.26 , pp. 5468
- Boyault, C.¹ Sadoul, K.² Pabion, M.³ Khochbin, S.⁴

16
- 84863275305
- J. H. Kalin, H. Zhang, S. Gaudrel-Grosay, G. Vistoli, A. P. Kozikowski, Chem Med Chem, 2012, 7, 425
- (2012) Chem Med Chem , vol.7 , pp. 425
- Kalin, J.H.¹ Zhang, H.² Gaudrel-Grosay, S.³ Vistoli, G.⁴ Kozikowski, A.P.⁵

17
- 33746894565
- T. Suzuki, A. Kouketsu, Y. Itoh, S. Hisakawa, S. Maeda, M. Yoshida, H. Nakagawa, N. Miyata, J. Med. Chem., 2006, 49, 4809
- (2006) J. Med. Chem. , vol.49 , pp. 4809
- Suzuki, T.¹ Kouketsu, A.² Itoh, Y.³ Hisakawa, S.⁴ Maeda, S.⁵ Yoshida, M.⁶ Nakagawa, H.⁷ Miyata, N.⁸

18
- 71049156256
- J. M. Ontoria, S. Altamura, A. Di Marco, F. Ferrigno, R. Laufer, E. Muraglia, M. C. Palumbi, M. Rowley, R. Scarpelli, C. Schultz-Fademrecht, S. Serafini, C. Steinkühler, P. Jones, J. Med. Chem., 2009, 52, 6782
- (2009) J. Med. Chem. , vol.52 , pp. 6782
- Ontoria, J.M.¹ Altamura, S.² Di Marco, A.³ Ferrigno, F.⁴ Laufer, R.⁵ Muraglia, E.⁶ Palumbi, M.C.⁷ Rowley, M.⁸ Scarpelli, R.⁹ Schultz-Fademrecht, C.¹⁰ Serafini, S.¹¹ Steink, C.¹² Ühlerjones, P.¹³

19
- 58549085379
- D. V. Smil, S. Manku, Y. A. Chanigny, S. Leit, A. Wahhab, T. P. Yan, M. Fournel, C. Maroun, Z. Li, A. M. Lemieux, A. Nicolescu, J. Rahil, S. Lefebvre, A. Panetta, J. M. Besterman, R. Déziel, Bioorg. Med. Chem. Lett., 2009, 19, 688
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 688
- Smil, D.V.¹ Manku, S.² Chanigny, Y.A.³ Leit, S.⁴ Wahhab, A.⁵ Yan, T.P.⁶ Fournel, M.⁷ Maroun, C.⁸ Li, Z.⁹ Lemieux, A.M.¹⁰ Nicolescu, A.¹¹ Rahil, J.¹² Lefebvre, S.¹³ Panetta, A.¹⁴ Besterman, J.M.¹⁵ Déziel, R.¹⁶

20
- 38949141196
- S. Schüfer, L. Saunders, E. Eliseeva, A. Velena, M. Jung, A. Schwienhorst, A. Strasser, A. Dickmanns, R. Ficner, S. Schlimme, W. Sippl, E. Verdin, M. Jung, Bioorg. Med. Chem., 2008, 16, 2011
- (2008) Bioorg. Med. Chem. , vol.16 , pp. 2011
- Sch, S.¹ Üfersaunders, L.² Eliseeva, E.³ Velena, A.⁴ Jung, M.⁵ Schwienhorst, A.⁶ Strasser, A.⁷ Dickmanns, A.⁸ Ficner, R.⁹ Schlimme, S.¹⁰ Sippl, W.¹¹ Verdin, E.¹² Jung, M.¹³

21
- 72249094958
- C. A. Olsen, M. R. Ghadiri, J. Med. Chem., 2009, 52, 7836
- (2009) J. Med. Chem. , vol.52 , pp. 7836
- Olsen, C.A.¹ Ghadiri, M.R.²

22
- 60849105362
- S. Schüfer, L. Saunders, S. Schlimme, V. Valkov, J. M. Wagner, F. Kratz, W. Sippl, E. Verdin, M. Jung, ChemMedChem, 2009, 4, 283
- (2009) Chemmedchem , vol.4 , pp. 283
- Sch, S.¹ Üfersaunders, L.² Schlimme, S.³ Valkov, V.⁴ Wagner, J.M.⁵ Kratz, F.⁶ Sippl, W.⁷ Verdin, E.⁸ Jung, M.⁹

23
- 78149280636
- P. K. Gupta, R. C. Reid, L. G. Liu, A. J. Lucke, S. A. Broomfield, M. R. Andrews, M. J. Sweet, D. P. Fairlie, Bioorg. Med. Chem. Lett., 2010, 20, 7067
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 7067
- Gupta, P.K.¹ Reid, R.C.² Liu, L.G.³ Lucke, A.J.⁴ Broomfield, S.A.⁵ Andrews, M.R.⁶ Sweet, M.J.⁷ Fairlie, D.P.⁸

24
- 73349143672
- M. A. Rivieccio, C. Brochier, D. E. Willis, B. A. Walker, M. A. D'Annibale, K. McLaughlin, A. Siddiq, A. P. Kozikowski, S. R. Jaffrey, J. L. Twiss, R. R. Ratan, B. Langley, Proc. Natl. Acad. Sci. U. S. A., 2009, 106, 19599
- (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 19599
- Rivieccio, M.A.¹ Brochier, C.² Willis, D.E.³ Walker, B.A.⁴ D'annibale, M.A.⁵ McLaughlin, K.⁶ Siddiq, A.⁷ Kozikowski, A.P.⁸ Jaffrey, S.R.⁹ Twiss, J.L.¹⁰ Ratan, R.R.¹¹ Langley, B.¹²

25
- 0038274087
- J. C. Wong, R. Hong, S. L. Schreiber, J. Am. Chem. Soc., 2003, 125, 5586
- (2003) J. Am. Chem. Soc. , vol.125 , pp. 5586
- Wong, J.C.¹ Hong, R.² Schreiber, S.L.³

26
- 77955355838
- K. V. Butler, J. Kalin, C. Brochier, G. Vistoli, B. Langley, A. P. Kozikowski, J. Am. Chem. Soc., 2010, 132, 10842
- (2010) J. Am. Chem. Soc. , vol.132 , pp. 10842
- Butler, K.V.¹ Kalin, J.² Brochier, C.³ Vistoli, G.⁴ Langley, B.⁵ Kozikowski, A.P.⁶

27
- 84856390338
- J. H. Kalin, K. V. Butler, T. Akimova, W. W. Hancock, A. P. Kozikowski, J. Med. Chem., 2012, 55, 639
- (2012) J. Med. Chem. , vol.55 , pp. 639
- Kalin, J.H.¹ Butler, K.V.² Akimova, T.³ Hancock, W.W.⁴ Kozikowski, A.P.⁵

28
- 84870018107
- A. G. Dossetter, Med. Chem. Commun., 2012, 3, 1518
- (2012) Med. Chem. Commun. , vol.3 , pp. 1518
- Dossetter, A.G.¹

29
- 69249233597
- A. Sudhakara, H. Jayadevappa, H. N. H. Kumar, K. M. Mahadevan, Lett. Org. Chem., 2009, 6, 159
- (2009) Lett. Org. Chem. , vol.6 , pp. 159
- Sudhakara, A.¹ Jayadevappa, H.² Kumar, H.N.H.³ Mahadevan, K.M.⁴

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