Immune response from a resource allocation perspective

Frontiers in Genetics

Volumn 3, Issue DEC, 2012, Pages

  Rauw, Wendy M ^a  

^a INIA   (Spain)

Author keywords

Immune function; Life history theory; Resistance; Resource allocation; Robustness; Selection; Tolerance

Indexed keywords

ANIMALIA;

EID: 84876089728     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2012.00267     Document Type: Review

References (174)

1. Allen, D. E., and Little, T. J. (2011). Identifying energy constraints to parasite resistance. J. Evol. Biol. 24, 224-229.
2. Ayres, J. S., and Schneider, D. S. (2009). The role of anorexia in resistance and tolerance to infections in Drosophila. PLoS Biol. 7:e1000150. doi: 10.1371/journal.pbio.1000150
3. Ayres, J. S., and Schneider, D. S. (2012). Tolerance of infections. Annu. Rev. Immunol. 30, 271-294.
4. Baldwin,R.L.,Smith,N.E., Taylor, J., and Sharp, M. (1980). Manipulating metabolic parameters to improve growth rate and milk secretion. J. Anim. Sci. 51, 1416-1428.
5. Baracos,E.,Whitmore,W.T.,andGale, R. (1987). The metabolic cost of fever. Can. J. Physiol. Pharmacol. 65, 1248-1254.
6. Barger, I. A. (1993). Influence of sex and reproductive status on susceptibility of ruminants to nematode parasitism. Int. J. Parasitol. 23, 463-469.
7. Barnes,D.M.,Song,Z.,Klasing,K. C., and Bottje, W. (2002). Protein metabolism during an acute phase response in chickens. Amino Acids 22, 15-26.
8. Bates, P. C., and Millward, D. J. (1981). Characteristics of skeletal muscle growth and protein turnover in a fast-growing rat strain. Br.J.Nutr. 46, 7-13.
9. Bauman, D. E., and Currie, W. B. (1980). Partitioning of nutrients during lactation: a review of mechanisms involving homeostasis and homeorhesis. J. Dairy Sci. 63, 1514-1529.
10. Bayyari,G.R.,Huff,W.E.,Rath, N.C.,Balog,J.M.,Newberry,L. A., Villines, J. D., et al. (1997). Effect of the genetic selection of turkeys for increased body weight and egg production on immune and physiological responses. Poult. Sci. 76, 289-296.
11. Behnke, J. M., Bernard, C. J., and Wakelin, D. (1992). Understanding chronic nematode infections: evolutionary considerations, current hypotheses and the way forward. Int. J. Parasitol. 22, 861-907.
12. Beilharz, R. G., Luxford, B. G., and Wilkinson, J. L. (1993). Quantitative genetics and evolution: is our understanding of genetics sufficient to explain evolution? J. Anim. Breed. Genet. 110, 161-170.
13. Beisel, W. R. (1977). Magnitude of the host nutritional responses to infection. Am.J.Clin.Nutr.30, 1236-1247.
14. Bessey, P. Q. (2004). "Metabolic response to critical illness," in ASC Surgery: Principles and Practice, 1-27. Available online at: http://129.49.170.167/Volumes/ACS CD+July+2010/ACSCD/pdf/ACS08 25.pdf
15. Best,A.,White,A.,and Boots,M. (2009). Resistance is futile but tolerance can explain why parasites do not always castrate their hosts. Evolution 64, 348-357.
16. Bishop,S.C.,Chesnais,J.,andStear, M. J. (2002). "Breeding for disease resistance: issues and opportunities," in Proceedings of the 7th WCGALP (Montpellier, France), 1-8.
17. Bisset, S. A., Morris, C. A., McEwan, J. C., and Vlassoff, A. (2001). Breeding sheep in New Zealand that are less reliant on helminthics to maintain health and productivity. N.Z. Vet. J. 49, 236-246.
18. Boggs, C. L. (1992). Resource allocation: exploring connections between foraging and life history. Funct. Ecol. 6, 508-518.
19. Bowden, L., Dheilly, N. M., Raftos, D. A., and Nair, S. V. (2007). New immune systems: pathogenspecific host defence, life history strategies and hypervariable immune-response genes of invertebrates. ISJ 4, 127-136.
20. Brommer, J. E. (2000). The evolution of fitness in life-history theory. Biol. Rev. 75, 377-404.
21. Butter,N.L.,Dawson,J.M.,Wakelin, D., and Buttery, P. J. (2000). Effect of dietary tannin and protein concentration on nematode infection (Trichostrongylus colubriformis)in lambs. J. Agr. Sci. 134, 89-99.
22. Cohen, J. (2002). The immunopathogenesis of sepsis. Nature 420, 885-891.
23. Colditz, I. G. (2009). "Allocation of resources to immune responses," in Resource Allocation Theory Applied to Farm Animal Production,edW. M. Rauw (Wallingford, UK: CABI Publishing), 192-209.
24. Collier,R.J.,Baumgard,L.H.,Lock, A. L., and Bauman, D. E. (2005). "Physiological limitations, nutrient partitioning," in Yields of Farmed Species: Constraints and Opportunities in the 21st Century, eds J. Wiseman and R. Sylvestor (Nottingham, UK: Nottingham University Press), 351-378.
25. Collier,R.J.,Limesand,S.W.,Rhoads, M. L., Rhoads, R. P., and Baumgard, L. H. (2009). "Homeorhesis during heat stress," in Resource Allocation Theory Applied to Farm Animal Production,edW.M. Rauw (Wallingford, UK: CABI Publishing), 72-88.
26. Coltherd,J.C.,Bünger,L.,Kyriazakis, I., and Houdijk, J. G. M. (2009). Genetic growth potential interacts with nutrition on the ability of mice to cope with Heligmosomoides bakeri infection. Parasitology 136, 1043-1055.
27. Coop, R. L., and Kyriazakis, I. (1999). Nutrition-parasite interaction. Vet. Parasitol. 84, 187-204.
28. Coop,R.L.,andSykes,A.R. (2002). "Interaction between gastrointestinal parasites and nutrints," in Sheep Nutrition,edsM. Freer and H. Dove (Wallingford, UK: CABI Publishing), 387.
29. Coustau, C., Chevillon, C., and French-Constant, R. F. (2000). Resistance to xenobiotics and parasites: can we count the cost? Trends Ecol. Evol. 15, 378-383.
30. Cucco, M., Pellegrino, I., and Malacarne, G. (2010). Immune challenge affects female condition and egg size in the grey partridge. J. Exp. Zool. A Ecol. Genet. Physiol. 313, 597-604.
31. Darwin, C. (1872). On the Origin of Species by Natural Selection, or the Preservation of Favoured Races in the Struggle for Life. London, UK: John Murray.
32. Datta,F.U.,Nolana,J.V.,Rowe,J. B., and Gray, G. D. (1998). Protein supplementation improves the performance of parasitized sheep fed a straw-based diet. Int. J. Parasitol. 28, 1269-1278.
33. Deerenberg,C.,Apanius,V.,Daan,S., and Bos, N. (1997). Reproductive effort decreases antibody responsiveness. Proc. R. Soc. Lond. B 264, 1021-1029.
34. De Jong, G. (1994). The fitness of fitness concepts and the description of natural selection. Quart. Rev. Biol. 69, 3-29.
35. Demas,G.E.,Chefer,V.,Talan, M. I., and Nelson, R. J. (1997). Metabolic costs of mounting an antigen-stimulated immune response in adult and aged C57BL/6J mice. Am. J. Physiol. 273, R1631-R1637.
36. Derting, T. L., and Compton, S. (2003). Immune response, not immune maintenance, is energetically costly in wild white-footed mice (Peromyscus leucopus). Physiol. Biochem. Zool. 76, 744-752.
37. DiAngelo, J. R., Bland, M. L., Bambina, S.,Cherry,S.,andBirnbaum,M. J. (2009). The immune response attenuates growth and nutrient storage in Drosophila by reducing insulin signaling. Proc. Natl. Acad. Sci. U.S.A. 106, 20853-20858.
38. Doeschl-Wilson, A., Sawalha, R., Gubbins, S., and Villanueva, B. (2009). Implications of conflicting associations of the prion protein (PrP) gene with scrapie susceptibility and fitness on the persistence of scrapie. PLoS ONE 4:e7970. doi: 10.1371/journal.pone.0007970
39. Donabedian, H. (2006). Nutritional therapy and infectious diseases: a two-edged sword. Nutr. J. 5, 21-31.
40. Duffy, M. A., and Forde, S. E. (2009). Ecological feedbacks and the evolution of resistance. J. Anim. Ecol. 78, 1106-1112.
41. Dunnington, E. A. (1990). "Selection and homeostasis," in Proceedings of the 4th WCGALP (Edinburgh, UK), 5-12.
42. Eady, S. J., Woolaston, R. R., Mortimer, S. I., Lewer, R. P., Raadsma, H. W., Swan, A. A., et al. (1996). Resistance to nematode parasites in Merino sheep: sources of genetic variation. Aust. J. Agr. Res. 47, 895-915.
43. Elia, M. (1992). "Organ and tissue contribution to metabolic rate," in Energy Metabolism: Tissue Determinants and Cellular Corollaries, eds J. M. McKinney and H. N. Tucker (New York, NY: Raven), 61-77.
44. Emanuelsson, U. (1988). Recording of production disease in cattle and possibilities for genetic improvements: a review. Livest. Prod. Sci. 20, 89-106.
45. Festa-Bianchet, M. (1989). Individual differences, parasites, and the costs of reproduction for bighorn ewes (Ovis Canadensis). J. Anim. Ecol. 58, 785-795.
46. Forbes, J. M. (2007). "Diet selection: practicalities," in Voluntary Food Intake and Diet Selection in Farm Animals,edJ.M. Forbes (Wallingford, UK: CABI Publishing), 453.
47. Fornoni, J., Nunez-Farfán, J., Valverde, P. L., and Rausher, M. D. (2004). Evolution of mixed strategies of plant defense allocation against natural enemies. Evolution 58, 1685-1695.
48. Freitak,D.,Ots,I.,Vanatoa,A.,and Hõrak, P. (2003). Immune response is energetically costly in white cabbage butterfly pupae. Proc. Biol. Sci. 270(Suppl.), S220-S222.
49. French,S.S.,DeNardo,D.F.,and Moore, M. C. (2007). Tradeoffs between the reproductive and immune systems: facultative responses to resources or obligate responses to reproduction? Am. Nat. 170, 79-89.
50. Friggens, N. C., and Van der Waaij, E. H. (2009). "Modelling of resource allocation patterns," in Resource Allocation Theory Applied to Farm Animal Production,edW.M. Rauw (Wallingford, UK: CABI Publishing), 302-320.
51. Glazier, D. S. (2009a). "Resource allocation patterns," in Resource Allocation Theory Applied to Farm Animal Production,edW.M. Rauw (Wallingford, UK: CABI Publishing), 22-43.
52. Glazier, D. S. (2009b). "Trade-offs," in Resource Allocation Theory Applied to Farm Animal Production,edW. M. Rauw (Wallingford, UK: CABI Publishing), 44-60.
53. Gross, W. B., Siegel, P. B., and Pierson, F. W. (2002). Effects of genetic selection for high or low antibody response on resistance to a variety of disease challenges and the relationship of resource allocation. Avian Dis. 46, 1007-1010.
54. Haldane, J. B. S. (1949). Disease and evolution. Ric. Sci. Suppl. A 19, 68-76.
55. Han, P. F. S., and Smyth, J. R. Jr. (1972). The influence of growth rate on the development of Marek's disease in chickens. Poult. Sci. 51, 975-985.
56. Hanssen, S. A., Hasselquist, D., Folstad, I., and Erikstad, K. E. (2004). Costs of immunity: immune responsiveness reduces survival in a vertebrate. Proc. Biol. Sci. 271, 925-930.
57. Hasday, J. D., Fairchild, K. D., and Shanhotz, C. (2000). The role of fever in the infected host. Microbes Infect. 2, 1891-1904.
58. Hawkins, A. J. S. (1991). Protein turnover: a functional appraisal. Funct. Ecol. 5, 222-233.
59. Heringstad, B., Klemetsdal, G., and Ruane, J. (2000). Selection for mastitis resistance in dairy cattle: a review with focus on the situation in the Nordic countries. Livest. Prod. Sci. 64, 95-106.
60. Heringstad, B., Klemetsdal, G., and Steine, T. (2003). Selection responses for clinical mastitis and protein yield in two Norwegian dairy cattle selection experiments. J. Dairy Sci. 86, 2990-2999.
61. Hoeve,M.A.,Mylonas,K.J.,Fairlie-Clarke, K. J., Mahajan, S. M., Allen, J. E., and Graham, A. L. (2009). Plasmodium chabaudi limits early Nippostrongylus brasiliensis-induced pulmonary immune activation and Th2 polarization in co-infected mice. BMC Immunol. 10:60. doi: 10.1186/1471-2172-10-60
62. Houdijk, J. G. M., and Athanasiadou, S. (2003). "Direct and indirect effects of host nutrition on ruminant gastrointestinal nematodes," in VI International Symposium on the Nutrition of Herbivores, (Mérida, Mexico), 213-236.
63. Houdijk,J.G.M.,Jessop,N.S.,and Kyriazakis, I. (2001). Nutrient partitioning between reproductive and immune functions in animals. Proc. Nutr. Soc. 60, 515-525.
64. Howse, S. W., Blair, H. T., Garrick, D. J., and Pomroy, W. E. (1992). A comparison of internal parasitism in fleece-weight selected and control Romney sheep. Proc.N.Z.Soc. Anim. Prod. 52, 57-60.
65. Janeway, C. A., and Medzhitov, R. (2002). Innate immune recognition. Annu. Rev. Immunol. 20, 1-28.
66. Johnson, P. T. J., Rohr, J. R., Hoverman, J. T., Kellermanns, E., Bowerman, J., and Lunde, K. B. (2012). Living fast and dying of infection: host life history drives interspecific variation in infection and disease risk. Ecol. Lett. 15, 235-242.
67. Jokela, J., Schmid-Hempel, P., and Rigby, M. C. (2000). Dr. Pangloss restrained by the Red Queen - steps towards a unified defence theory. OIKOS 89, 267-274.
68. Katona, P., and Katona-Apte, J. (2008). The interaction between nutrition and infection. Clin. Infect. Dis. 46, 1582-1588.
69. Kelley, K. W. (1980). Stress and immune function: a bibliographic review. Ann. Rech. Vét. 11, 445-478.
70. Klasing, K. C., Laurin, D. E., Peng, R. K., and Fry, D. M. (1987). Immunologically mediated growth depression in chicks: influence of feed intake, corticosterone and interleukin-1. J. Nutr. 117, 1629-1637.
71. Kluger,M.J.,Kozak,W.,Conn,C. A.,Leon,L.R.,andSoszynski,D. (1998). Role of fever in disease. Ann. N.Y. Acad. Sci. 856, 224-233.
72. Knap, P. W. (2005). Breeding robust pigs. Aust.J.Exp.Agr.45, 763-773.
73. Knap, P. W. (2009). "Robustness," in Resource Allocation Theory Applied to Farm Animal Production,edW. M. Rauw (Wallingford, UK: CABI Publishing), 288-301.
74. Knap, P. W., and Bishop, S. C. (1996). "Relationships between genetic change and infectious disease in domestic livestock," in The Challenge of Genetic Change in Animal Production, eds W. G. Hill, S.C.Bishop,B.McGuirk,J.C. McKay, G. Simm, and A. J. Webb (Edinburgh, UK: British Society of Animal Science). Available online at: http://www.bsas.org.uk/publs/ genchng/paper8.pdf
75. Knox, M., and Steel, J. (1996). Nutritional enhancement of parasite control in small ruminant production systems in developing countries of south-east Asia and the Pacific. Int. J. Parasitol. 26, 963-970.
76. Koenen, M. E., Boonstra-Blom, A. G., and Jeurissen, S. H. M. (2002). Immunological differences between layer and broiler-type chickens. Vet. Immunol. Immunopathol. 89, 47-56.
77. Kogut, M. H. (2009). Impact of nutrition on the innate immune response to infection in poultry. J. Appl. Poultry Res. 18, 111-124.
78. Kraaijeveld,A.R.,andGodfray,H. C. J. (2008). Selection for resistance to a fungal pathogen in Drosphila melanogaster. Heredity 100, 400-406.
79. Kyriazakis, I., and Houdijk, J. (2006). Immunonutrition: nutritional control of parasites. Small Ruminant Res. 62, 79-82.
80. Kyriazakis, I., Oldham, J. D., Coop, R. L., and Jackson, F. (1994). The effect of subclinical intestinal nematode infection on the diet selection of growing sheep. Br.J.Nutr.72, 665-677.
81. Kyriazakis, I., Tolkamp, B. J., and Hutchings, M. R. (1998). Towards a functional explanation for the occurrence of anorexia during parasitic infections. Anim. Behav. 56, 265-274.
82. Lamont, S. J., Pinard-Van der Laan, M. H., Cahaner, A., Van der Poel,J.J.,andParmentier,H. K. (2003). "Selection for disease resistance: direct selection ontheimmuneresponse,"in Poultry Genetics, Breeding and Biotechnology,edsW.M.Muirand S. E. Aggrey (Wallingford, UK: CABI Publishing), 399-418.
83. Lee, K. A. (2006). Linking immune defenses and life history at the levels of the individual and the species. Integr. Comp. Biol. 46, 1000-1015.
84. Lee, K. A., Wikelski, M., Robinson, W. D.,Robinson,T.R.,andKlasing, K. C. (2008). Constitutive immune defences correlate with life-history variables in tropical birds. J. Anim. Ecol. 77, 356-363.
85. Lee,K.P.,Cory,J.S.,Wilson,K., Raubenheimer, D., and Simpson, S. J. (2006). Flexible diet choice offsets protein costs of pathogen resistance in a caterpillar. Proc. Biol. Sci. 273, 823-829.
86. Le Floc'h, N., Melchior, D., and Obled, C. (2004). Modifications of protein and amino acid metabolism during inflammation and immune sytem activation. Livest. Prod. Sci. 87, 37-45.
87. Leroi, A. M. (2001). Molecular signals versus the loi de balancement. Trends Ecol. Evol. 16, 24-29.
88. Lobley, G. E. (2003). Protein turnover - what does it mean for animal production? Can. J. Anim. Sci. 83, 327-340.
89. Lochmiller, R. L., and Deerenberg, C. (2000). Trade-offs in evolutionary immunology: just what is the cost of immunity? OIKOS 88, 87-98.
90. Martin, A., Dunnington, E. A., Gross, W. B., Briles, W. E., Briles, R. W., and Siegel, P. B. (1990). Production traits and alloantigen systems in lines of chickens selected for high or low antibody responses to sheep erythrocytes. Poult. Sci. 69, 871-878.
91. Martin,L.B.,Scheuerlein,A.L.,and Wikelski, M. (2003). Immune activity elevates energy expenditure of house sparrows: a link between direct and indirect costs? Proc. Biol. Sci. 270, 153-158.
92. Mauck, R. A., Matson, K. D., Philipsborn, J., and Ricklefs, R. E. (2005). Increase in the constitutive innate humoral immune system in Leach's Storm-Petrel (Oceanodroma leucorhoa)chicksis negatively correlated with growth rate. Funct. Ecol. 19, 1001-1007.
93. Mauricio, R., Rausher, M. D., and Burdick, D. S. (1997). Variation in the defense strategies of plants: are resistance and tolerance mutually exclusive? Ecology 78, 1301-1311.
94. McDade, T. W. (2005). Life history, maintenance, and the early origins of immune function. Am. J. Hum. Biol. 17, 81-94.
95. McFall-Ngai, M. (2007). Care for the community. Nature 445, 11.
96. McNamara, J. M., and Buchanan, K. L. (2005). Stress, resource allocation, and mortality. Behav. Ecol. 16, 1008-1017.
97. Miller, L. L., Siegel, P. B., and Dunnington, E. A. (1992). Inheritance of antibody response to sheep erythrocytes in lines of chickens divergently selected for 56 day body weight and their crosses. Poult. Sci. 71, 47-52.
98. Moberg, G. P. (2000). "Biological response to stress: implications for animal welfare," in The Biology of Animal Stress,eds G.P.Moberg and J. A. Mench (Wallingford, UK: CABI Publishing), 1-22.
99. Møller, A. P., Christe, Ph., Erritzøe, J., and Mavarez, J. (1998). Condition, disease and immune defence. OIKOS 83, 301-306.
100. Møller, A. P., and Saino, N. (2004). Immune response and survival. OIKOS 104, 299-304.
101. Mormède, P., Foury, A., Terenina, E., and Knap, P. W. (2010). Breeding for robustness: the role of cortisol. Animal 5, 651-657.
102. Moreno, J., Sanz, J. J., and Arriero, E. (1999). Reproductive effort and T-lymphocyte cell-mediated immunocompetence in female pied flycatchers Ficedula hypoleuca. Proc. Biol. Sci. 266, 1105-1109.
103. Morris, C. A., Vlassoff, A., Bisset, S. A., Baker,R.L.,Watson,T.G.,West,C. J., et al. (2000). Continued selection of Romney sheep for resistance or susceptibility to nematode infection: estimates of direct and correlated responses. Anim. Sci. 70, 17-27.
104. Nestor,K.E.,Noble,D.O.,Zhu,J., and Moritsu, Y. (1996a). Direct and correlated responses to long-term selection for increased body weight and egg production in turkeys. Poult. Sci. 75, 1180-1191.
105. Nestor,K.E.,Saif,Y.M.,Zhu,J., and Noble, D. O. (1996b). Influence of growth selection in turkeys on resistance to Pasteurella multocida. Poult. Sci. 75, 1161-1163.
106. Nilsson, J. Å. (2003). Ectoparasitism in marsh tits: costs and functional explanations. Behav. Ecol. 14, 175-181.
107. Nordling, D., Andersson, M., Zohari, S., and Gustafsson, L. (1998). Reproductive effort reduces specific immune response and parasite resistance. Proc. Biol. Sci. 265, 1291-1298.
108. Oddy,V.H.,Speck,P.A.,Warren,H. M., and Wynn, P. C. (1995). Protein metabolism in lambs from lines divergently selected for weaning weight. J. Agric. Sci. 124, 129-137.
109. Ots,I.,Kerimov,A.B.,Ivankina,E. V., Ilyina, T. A., and Hõr ak, P. (2001). Immune challenge affects basal metabolic activity in wintering great tits. Proc. Biol. Sci. 268, 1175-1181.
110. Panda, A. K., Raju, M. V. L. N., Rama Rao, S. V., Shyam Sunder, G., and Reddy, M. R. (2010). Effect of post-hatch feed deprivation on growth, immune organ development and immune competence in broiler chickens. Anim. Nutr. Feed Techn. 10, 9-17.
111. Pirlet, K., and Arthur-Goettig, A. (1999). Maintaining life and health by natural selection of protein molecules. J. Theor. Biol. 201, 75-85.
112. Povey, S., Cotter, S. C., Simpson, S. J., Lee, K. P., and Wilson, K. (2009). Can the protein costs of bacterial resistance be offset by altered feeding behavior? J. Anim. Ecol. 78, 437-446.
113. Princiotta, M. F., Finzi, D., Qian, S. B., Gibbs, J., Schuchmann, S., Buttgereit, F., et al. (2003). Quantitating protein synthesis, degradation, and endogenous antigen processing. Immunity 18, 343-354.
114. Pryce, J. E., Veerkamp, R. F., Thomposon, R., Hill, W. G., and Simm, G. (1997). Genetic aspects of common health disorders and measures of fertility in Holstein Friesian dairy cattle. Anim. Sci. 3, 353-360.
115. Qureshi, M. A., and Havenstein, G. B. (1994). A comparison of the immune performance of a 1991 commercial broiler with a 1957 ran-dombredstrainwhenfed'typical' 1957 and 1991 broiler diets. Poult. Sci. 73, 1805-1812.
116. Råberg,L.,Sim,D.,andRead,A.F. (2007). Disentangling genetic variation for resistance and tolerance to infectious diseases in animals. Science 318, 812-814.
117. Råberg, L., Vestberg, M., Hasselquist, D.,Holmdahl,R.,Svensson,E., and Nilsson, J. Å. (2002). Basal metabolic rate and the evolution of theadaptiveimmunesystem.Proc. Biol. Sci. 269, 817-821.
118. Rauw, W. M. (2007). Physiological consequences of selection for increased performance. Proc. Assoc. Advmt. Anim. Breed. Genet. 17, 240-247.
119. Rauw, W. M. (2009). "Introduction," in Resource Allocation Theory Applied to Farm Animal Production,edW. M. Rauw (Wallingford, UK: CABI Publishing), 1-21.
120. Rauw, W. M. (2012). "Feed efficiency and animal robustness," in Feed Efficiency in the Beef Industry,edR. A. Hill (West Sussex, UK: Wiley Blackwell), 105-122.
121. Rauw,W.M.,Kanis,E.,Noordhuizen-Stassen,E.N.,andGrommers,F.J. (1998). Undesirable side effects of selection for high production efficiency in farm animals: a review. Livest. Prod. Sci. 56, 15-33.
122. Raynal-Ljutovac, K., Pirisi, A., de Crémoux, R., and Gonzalo, C. (2007). Somatic cells of goat and sheep milk: analytical, sanitary, productive and technological aspects. Small Ruminant Res. 68, 126-144.
123. Reeds, P. J., and Jahoor, F. (2001). The amino acid requirement of disease. Clin. Nutr. 20, 15-22.
124. Restif, O., and Koella, J. C. (2004). Concurrent evolution of resistance and tolerance to pathogens. Am. Nat. 164, E90-E102.
125. Richardson,E.C.,andHerd,R.M. (2004). Biological basis for variation in residual feed intake in beef cattle. 2. Synthesis of results following divergent selection. Aust. J. Exp. Agric. 44, 431-440.
126. Ricklefs, R. E., and Wikelski, M. (2002). The physiology/life-history nexus. Trends Ecol. Evol. 17, 462-468.
127. Rigby, M. C., Hechinger, R. F., and Stevens, L. (2002). Why should parasite resistance be costly? Trends Parasitol. 18, 116-120.
128. Roff, D. A. (2007). Contributions of genomics to life-history theory. Nat. Rev. Genet. 8, 116-125.
129. Roy, B. A., and Kirchner, J. W. (2000). Evolutionary dynamics of pathogen resistance and tolerance. Evolution 54, 51-63.
130. Rupp, R., and Boichard, D. (2003). Genetics of resistance to mastitis in dairy cattle. Vet. Res. 34, 671-688.
131. Rupp, R., and Foucras, G. (2010). "Genetics of mastitis in dairy ruminants," in Breeding for Disease Resistance in Farm Animals,edsS.C.Bishop,R.F. E.Axford,F.W.Nicholas,andJ. B. Owen (Wallingford, UK: CABI Publishing), 183-212.
132. Sacco,R.E.,Saif,Y.M.,Nestor,K.E., Anthony, N. B., Emmerson, D. A., and Dearth, R. N. (1991). Genetic variation in resistance of turkeys to experimental challenge with pasteurella multocida. Avian Dis. 35, 950-954.
133. Saif,Y.M.,Nestor,K.E.,Dearth, R. N., and Renner, P. A. (1984). Possible genetic variation in resistance of turkeys to erysipelas and fowl cholera. Avian Dis. 28, 770-773.
134. Sakaguchi, S., Yamaguchi, T., Nomura, T., and Ono, M. (2008). Regulatory T cells and immune tolerance. Cell 133, 775-787.
135. Sandland, G. J., and Minchella, D. J. (2003). Costs of immune defense: anenigmawrappedinan environmental cloak? Trends Parasitol. 19, 571-574.
136. Saper, C. B., and Breder, C. D. (1994). The neurological basis of fever. N. Engl. J. Med. 330, 1880-1886.
137. Sawalha, R. M., Brotherstone, S., Conington, J., and Villanueva, B. (2007). Lambs with scrapie susceptible genotypes have higher postnatal survival. PLoS ONE 11:e1236. doi: 10.1371/journal.pone.0001236
138. Schluter, D., Price, T. D., and Rowe, L. (1991). Conflicting selection pressures and life-history trade-offs. Proc. Biol. Sci. 246, 11-17.
139. Schmid-Hempel, P. (2003). Variation in immune defence as a question of evolutionary ecology. Proc. Biol. Sci. 270, 357-366.
140. Schneider, D. S., and Ayres, J. S. (2008). Twowaystosurviveinfection:what resistance and tolerance can teach us about treating infectious diseases. Nat. Rev. 8, 889-895.
141. Segerstrom, S. C. (2007). Stress, energy, and immunity: an ecological view. Curr.Dir.Phychol.Sci.16, 326-330
142. Selye, H. (1953). The present state of stress conception. Munch. Med. Wochenschr. 95, 426-433.
143. Shubber, A. H., Lloyd, S., and Soulsby, E. J. L. (1981). Infection with gastrointestinal helminths. Effect of lactatin and meternal transfer of immunity. Z. Parasitenkd. 65, 181-189.
144. Simms, E. L. (2000). Defining tolerance as a norm of reaction. Evol. Ecol. 14, 563-570.
145. Speakman, J. R. (2008). The physiological costs of reproduction in small mammals. Philos. Trans. R. Soc. Lond. B Biol. Sci. 363, 375-398
146. Spurlock, M. E. (1997). Regulation of metabolism and growth during immune challenge: an overview of cytokine function. J. Anim. Sci. 75, 1773-1783.
147. Stear,M.J.,Bishop,S.C.,Mallard,B.A., and Raadsma, H. (2001). The sustainability, feasibility and desirability of breeding livestock for disease resistance. Res. Vet. Sci. 71, 1-7.
148. Svensson, E., and Råberg, L. (2010). Resistance and tolerance in animal enemy-victim coevolution. Trends Ecol. Evol. 25, 267-274.
149. Svensson, E., Råberg, L., Koch, C., and Hasselquist, D. (1998). Energetic stress, immunosuppression and the cost of an antibody response. Funct. Ecol. 12, 912-919.
150. Sykes, A. R. (2010). Host immune responses to nematodes: benefit or cost? Implications for future development of sustainable methods of control. Rev. Bras. Zoot. 39, 376-382.
151. Sykes, A. R., and Coop, R. L. (2001). Interactions between nutrition and gastrointestinal parasitism in sheep. N.Z. Vet. J. 49, 222-226.
152. Tavernarakis, N., and Driscoll, N. (2002). Caloric restriction and lifespan: a role for protein turnover?. Mech. Ageing Dev. 123, 215-229.
153. Thomas, F. M., Pym, R. A., and Johnson, R. J. (1991). Muscle protein turnover in chickens selected for increased growth rate, food consumption or efficiency of food utilization: effects of genotype and relationship to plasma IGF-I and growth hormone. Br. Poult. Sci. 32, 363-376.
154. Tomkins, A. M. (1986). Protein-energy malnutrition and risk of infection. Proc. Nutr. Soc. 45, 289-304.
155. Tort, L. (2011). Stress and immune modulation in fish. Dev. Comp. Immunol. 35, 1366-1375.
156. Tsai, H. J., Saif, Y. M., Nestor, K. E., Emmerson, D. A., and Patterson, R. A. (1992). Genetic variation in resistance of turkeys to experimental infection with Newcastle disease virus. Avian Dis. 36, 561-565.
157. Van der Most, P. J., De Jong, B., Permetier, H. K., and Verhulst, S. (2011). Trade-off between growth and immune function: a meta-analysis of selection experiments. Funct. Ecol. 25, 74-80.
158. Van Heugten, E. V., and Spears, J. W. (1997). Immune response and growth of stressed weanling pigs fed diets supplemented with organic or inorganic forms of chromium. J. Anim. Sci. 75, 409-416.
159. Van Houtert, M. F. J., Barger, I. A., Steel, J. W., Windon, R. G., and Emergy, D. L. (1995). Effects of dietary protein intake on responses of young sheep to infection with Trichostrongylus colubriformis. Ve t. Pa ra si t o l. 56, 163-180.
160. Van Straalen, N. M., and Roelofs, D. (2006). An Introduction to Ecological Genomics. Oxford, UK: Oxford University Press.
161. Veerkamp, R. F., Windig, J. J., Calus, M. P. L., Ouweltjes, W., De Haas, Y., and Beerda, B. (2009). "Selection for high production in dairy cattle," in Resource Allocation Theory Applied to Farm Animal Production, ed W. M. Rauw (Wallingford, UK: CABI Publishing), 243-260.
162. Verhulst, S., Riedstra, B., and Wiersma, P. (2005). Brood size and immunity costs in zebra finches Ta e n i o p y g i a guttata. J. Avian Biol. 36, 22-30.
163. Via, S., Gomulkiewicz, R., De Jong, G., Scheiner, S. M., Schlichting, C. D., and Van Tienderen, P. H. (1995). Adaptive phenotypic plasticity: consensus and controversy. Tr e n d s. E c o l. Evol. 10, 212-217.
164. Viney, M. E., Riley, E. M., and Buchanan, K. L. (2005). Optimal responses: immunocompetence revisited. Trends Ecol. Evol. 20, 665-669.
165. Walsh, T. S. (2007). "The metabolic response to injury," in Principles and Practice of Surgery, eds O. J. Garden, A. W. Bradbury, and J. Forsythe (Scotland: Churchill Livingstone), 2-9.
166. Warner, C. M., Meeker, D. L., and Rothschild, M. F. (1987). Genetic control of immune responsiveness: a review of its use as a tool for selection for disease resistance. J. Anim. Sci. 64, 394-406.
167. Webster Marketon, J. I., and Glaser, R. (2008). Stress hormones and immune function. Cell. Immunol. 252, 16-26.
168. Weiner, J. (1992). Physiological limits to sustainable energy budgets in birds and mammals: ecological implications. Tre nds Ec o l. Evol. 7, 384-388.
169. Wilkie, B., and Mallard, B. (1999). Selection for high immune response: an alternative approach to animal health maintenance? Vet. Immunol. Immunopathol. 72, 231-235.
170. Williams, N. H., Stahly, T. S., and Zimmerman, D. R. (1997). Effect of chronic immune system activation on the rate, efficiency, and composition of growth and lysine needs of pigs fed from 6 to 27 kg. J. Anim. Sci. 75, 2463-2471.
171. Xu, Y. C., Yang, D. B., and Wang, D. H. (2012). No evidence for a trade-off between reproductive investment and immunity in a rodent. PLoS ONE 7:e37182. doi: 10.1371/jour-nal.pone.0037182
172. Yewdell, J. W. (2001). Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing. Tr e n d s C e l l B i o l. 11, 294-297.
173. Zhao, X., and Lacasse, P. (2008). Mammary tissue damage during bovine mastitis: causes and control. J. Anim. Sci. 86, 57-65.
174. Zuk, M., and Stoehr, A. M. (2002). Immune defense and host life history. Am. Nat. 160, S9-S22.