TRP channels in dental pain

Open Pain Journal

Volumn 6, Issue SPEC.ISSUE.1, 2013, Pages 31-36

  Chung, Gehoon ^a   Oh, Seog Bae ^a  

^a Seoul National University   (South Korea)

Author keywords

Dental Pain; Mechanosensation; Odontoblast; Thermosensation; TRP

Indexed keywords

TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M3; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 2; VANILLOID RECEPTOR 3; VANILLOID RECEPTOR 4;

COLD; HEAT; HUMAN; MECHANOTRANSDUCTION; MOLECULAR MECHANICS; NONHUMAN; ODONTOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SENSORY NERVE; TEMPERATURE SENSITIVITY; TOOTH PAIN; TRIGEMINAL NERVE;

EID: 84876079130     PISSN: None     EISSN: 18763863     Source Type: Journal    
DOI: 10.2174/1876386301306010031     Document Type: Review

References (67)

1. Sessle BJ. The neurobiology of facial and dental pain: present knowledge, future directions. J Dent Res 1987; 66: 962-81.
2. Patapoutian A, Tate S, Woolf CJ. Transient receptor potential channels: targeting pain at the source. Nat Rev Drug Discov 2009; 8: 55-68.
3. Azerad J, Woda A. Sensation evoked by bipolar intrapulpal stimulation in man. Pain 1977; 4: 145-52.
4. Bender IB. Pulpal pain diagnosis--a review. J Endod 2000; 26: 175-9.
5. Nair PN, Schroeder HE. Number and size spectra of nonmyelinated axons of human premolars. Anat Embryol 1995; 192: 35-41.
6. Abd-Elmeguid A, Yu DC. Dental pulp neurophysiology: part 1. Clinical and diagnostic implications. J Can Dent Assoc 2009; 75: 55-9.
7. Anderson DJ, Hannam AG, Mathews B. Sensory mechanisms in mammalian teeth and their supporting structures. Physiol Rev 1970; 50: 171-95.
8. Trowbridge HO. Review of dental pain--histology and physiology. J Endod 1986; 12: 445-52.
9. Anderson DJ, Matthews B. Osmotic stimulation of human dentine and the distribution of dental pain thresholds. Arch Oral Biol 1967; 12: 417-26.
10. Edwall L, Olgart L. A new technique for recording of intradental sensory nerve activity in man. Pain 1977; 3: 121-5.
11. Ahlquist ML, Edwall LG, Franzén OG, Haegerstam GA. Perception of pulpal pain as a function of intradental nerve activity. Pain 1984; 19: 353-66.
12. Eckert SP, Taddese A, McCleskey EW. Isolation and culture of rat sensory neurons having distinct sensory modalities. J Neurosci Methods 1997; 77: 183-90.
13. Matthews B, Baxter J, Watts S. Sensory and reflex responses to tooth pulp stimulation in man. Brain Res 1976; 113: 83-94.
14. Paik SK, Park KP, Lee SK, et al. Light and electron microscopic analysis of the somata and parent axons innervating the rat upper molar and lower incisor pulp. Neuroscience 2009; 162: 1279-86.
15. Cadden SW, Lisney SJ, Matthews B. Thresholds to electrical stimulation of nerves in cat canine tooth-pulp with A beta-, A deltaand C-fibre conduction velocities. Brain Res 1983; 261: 31-41.
16. Fried K, Sessle BJ, Devor M. The paradox of pain from tooth pulp: Low-threshold "algoneurons"? Pain 2011; 152: 2685-9.
17. Son AR, Yang YM, Hong JH, Lee SI, Shibukawa Y, Shin DM. Odontoblast TRP channels and thermo/mechanical transmission. J Dent Res 2009; 88: 1014-9.
18. Allard B, Magloire H, Couble ML, Maurin JC, Bleicher F. Voltage-gated sodium channels confer excitability to human odontoblasts: possible role in tooth pain transmission. J Biol Chem 2006; 281: 29002-10.
19. Magloire H, Lesage F, Couble ML, Lazdunski M, Bleicher F. Expression and localization of TREK-1 K+ channels in human odontoblasts. J Dent Res 2003; 82: 542-5.
20. Okumura R, Shima K, Muramatsu T, et al. The odontoblast as a sensory receptor cell? The expression of TRPV1 (VR-1) channels. Arch Histol Cytol 2005; 68: 251-7.
21. Allard B, Couble ML, Magloire H, Bleicher F. Characterization and gene expression of high conductance calcium-activated potassium channels displaying mechanosensitivity in human odontoblasts. J Biol Chem 2000; 275: 25556-61.
22. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997; 389: 816-24.
23. Balla Z, Szöke E, Czéh G, Szolcsányi J. Effect of capsaicin on voltage-gated currents of trigeminal neurones in cell culture and slice preparations. Acta Physiol Hung 2001; 88: 173-96.
24. Caterina MJ, Rosen TA, Tominaga M, Brake AJ, Julius D. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 1999; 398: 436-41.
25. Ichikawa H, Sugimoto T. Vanilloid receptor 1-like receptorimmunoreactive primary sensory neurons in the rat trigeminal nervous system. Neuroscience 2000; 101: 719-25.
26. Park C-K, Kim MS, Fang Z, et al. Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: implication for tooth pain. J Biol Chem 2006; 281: 17304-11.
27. Kim HY, Chung G, Jo HJ, et al. Characterization of dental nociceptive neurons. J Dent Res 2011; 90: 6 771-6.
28. Chaudhary P, Martenson ME, Baumann TK. Vanilloid receptor expression and capsaicin excitation of rat dental primary afferent neurons. J Dent Res 2001; 80: 1518-23.
29. Gibbs JL, Melnyk JL, Basbaum AI. Differential TRPV1 and TRPV2 channel expression in dental pulp. J Dent Res 2011; 90: 765-70.
30. Chung G, Jung SJ, Oh SB. The transient receptor potential family in pain and temperature sensation. In: Beaulieu P, Lussier D, Porreca F, Dickenson AH, Eds. Pharmacology of Pain, Seattle: IASP Press 2010; pp. 327-46.
31. Chung M-K, Lee J, Duraes G, Ro JY. Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal ganglia. J Dent Res 2011; 90: 1103-7.
32. Haas ET, Rowland K, Gautam M. Tooth injury increases expression of the cold sensitive TRP channel TRPA1 in trigeminal neurons. Arch Oral Biol 2011; 56: 1604-9.
33. Shibukawa Y, Suzuki T. A voltage-dependent transient K(+) current in rat dental pulp cells. Jpn J Physiol 2001; 51: 345-53.
34. Shibukawa Y, Suzuki T. Ca2+ signaling mediated by IP3-dependent Ca2+ releasing and store-operated Ca2+ channels in rat odontoblasts. J Bone Miner Res 2003; 18: 30-8.
35. Lundquist P, Lundgren T, Gritli-Linde A, Linde A. Na+/Ca2+ exchanger isoforms of rat odontoblasts and osteoblasts. Calcif Tissue Int 2000; 67: 60-7.
36. Yeon K-Y, Chung G, Shin MS, Jung SJ, Kim JS, Oh SB. Adult rat odontoblasts lack noxious thermal sensitivity. J Dent Res 2009; 88: 328-32.
37. Karim El IA, Linden GJ, Curtis TM, et al. Human odontoblasts express functional thermo-sensitive TRP channels: implications for dentin sensitivity. Pain 2011; 152: 2211-23.
38. Karim El IA, Linden GJ, Curtis TM, et al. Human dental pulp fibroblasts express the "cold-sensing" transient receptor potential channels TRPA1 and TRPM8. J Endod 2011; 37: 473-8.
39. Noël J, Zimmermann K, Busserolles J, et al. The mechanoactivated K+ channels TRAAK and TREK-1 control both warm and cold perception. EMBO J 2009; 28: 1308-18.
40. Magloire H, Maurin JC, Couble ML, et al. Topical review. Dental pain and odontoblasts: facts and hypotheses. J Orofac Pain 2010; 24: 335-49.
41. Van Hassel HJ. Physiology of the human dental pulp. Oral Surg Oral Med Oral Pathol 1971; 32: 126-34.
42. Heyeraas KJ, Berggreen E. Interstitial fluid pressure in normal and inflamed pulp. Crit Rev Oral Biol Med 1999; 10: 328-36.
43. Brannstrom M, Astroem A. A Study on the mechanism of pain elicited from the dentin. J Dent Res 1964; 43: 619-25.
44. Brannstrom M. The hydrodynamic theory of dentinal pain: sensation in preparations, caries, and the dentinal crack syndrome. J Endod 1986; 12: 453-7.
45. Ahlquist M, Franzén O, Coffey J, Pashley D. Dental pain evoked by hydrostatic pressures applied to exposed dentin in man: a test of the hydrodynamic theory of dentin sensitivity. J Endod 1994; 20: 130-4.
46. Chung G, Oh SB. Ion channels with mechanosensitivity in the nervous system. In: Kamkin A, Kiseleva I, Eds. Mechanosensitivity of the nervous system, vol. 2, Springer 2009; pp. 23-49.
47. Wei X, Edelmayer RM, Yan J, Dussor G. Activation of TRPV4 on dural afferents produces headache-related behavior in a preclinical rat model. Cephalalgia 2011; 31: 1595-600.
48. Vriens J, Owsianik G, Hofmann T, et al. TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron 2011; 70: 482-94.
49. Corey DP, García-Añoveros J, Holt JR, et al. TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature 2004; 432: 723-30.
50. Kwan KY, Allchorne AJ, Vollrath MA, et al. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron 2006; 50: 277-89.
51. Bautista DM, Jordt S-E, Nikai T, et al. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 2006; 124: 1269-82.
52. Birder LA, Nakamura Y, Kiss S, et al. Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nat Neurosci 2002; 5: 856-60.
53. Rong W, Hillsley K, Davis JB, Hicks G, Winchester WJ, Grundy D. Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice. J Physiol (Lond) 2004; 560: 867-81.
54. Sharif-Naeini R, Witty M-F, Séguéla P, Bourque CW. An Nterminal variant of Trpv1 channel is required for osmosensory transduction. Nat Neurosci 2006; 9: 93-8.
55. Cavanaugh DJ, Lee H, Lo L, Shields SD, Zylka MJ, Basbaum AI, Anderson DJ. Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci USA 2009; 106: 9075-80.
56. Abrahamsen B, Zhao J, Asante CO, et al. The cell and molecular basis of mechanical, cold, and inflammatory pain. Science 2008; 321: 702-5.
57. Basbaum AI, Bautista DM, Scherrer G, Julius D. Cellular and molecular mechanisms of pain. Cell 2009; 139: 267-84.
58. Cavanaugh DJ, Chesler AT, Bráz JM, Shah NM, Julius D, Basbaum AI. Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci 2011; 31: 10119-27.
59. Chung M-K, Jue SS, Dong X. Projection of Non-peptidergic afferents to mouse tooth pulp. J Dent Res 2012; 91: 777-82.
60. Närhi MV, Hirvonen TJ, Hakumäki MO. Responses of intradental nerve fibres to stimulation of dentine and pulp. Acta Physiol Scand 1982; 115: 173-8.
61. Tal M. The threshold for eliciting the jaw opening reflex in rats is not increased by neonatal capsaicin. Behav Brain Res 1984; 13: 197-200.
62. Fried K, Aldskogius H, Hildebrand C. Proportion of unmyelinated axons in rat molar and incisor tooth pulps following neonatal capsaicin treatment and/or sympathectomy. Brain Res 1988; 463: 118-23.
63. Muraki K, Iwata Y, Katanosaka Y, et al. TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes. Circ Res 2003; 93: 829-38.
64. Liedtke WB, Heller S, Harteneck C, Schultz G. TRPV4 and TRPM3 as Volume-Regulated Cation Channels. Boca Raton (FL): CRC Press 2007.
65. Grimm C, Kraft R, Sauerbruch S, Schultz G, Harteneck C. Molecular and functional characterization of the melastatin-related cation channel TRPM3. J Biol Chem 2003; 278: 21493-501.
66. Strotmann R, Harteneck C, Nunnenmacher K, Schultz G, Plant TD. OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat Cell Biol 2000; 2: 695-702.
67. Yu V, Damek-Poprawa M, Nicoll SB, Akintoye SO. Dynamic hydrostatic pressure promotes differentiation of human dental pulp stem cells. Biochem Bioph Res Co 2009; 386: 661-5.