Dental pulp neurophysiology: Part 1. Clinical and diagnostic implications

Journal of the Canadian Dental Association

Volumn 75, Issue 1, 2009, Pages 55-59

  Abd Elmeguid, Ashraf ^a   Yu, Donald C ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COLD; DENTIN; DENTIN SENSITIVITY; HEAT; HUMAN; INNERVATION; MYELINATED NERVE; NEUROGENIC INFLAMMATION; NONMYELINATED NERVE; OSMOTIC PRESSURE; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; TOOTH PAIN; TOOTH PULP; TOOTH PULP DISEASE; TRIGEMINAL NERVE;

COLD TEMPERATURE; DENTAL PULP; DENTAL PULP TEST; DENTIN SENSITIVITY; DENTINAL FLUID; HOT TEMPERATURE; HUMANS; NERVE FIBERS, MYELINATED; NERVE FIBERS, UNMYELINATED; NEUROGENIC INFLAMMATION; OSMOTIC PRESSURE; TOOTHACHE; TRIGEMINAL NERVE;

EID: 60149094305     PISSN: 07098936     EISSN: 14882159     Source Type: Journal    
DOI: None     Document Type: Review

References (47)

1. Hill CM. The efficacy of transillumination in vitality tests. Int Endod J 1986; 19(4):198-201.
2. Tronstad L. Root resorption - etiology, terminology and clinical manifestations. Endod Dent Traumatol 1988; 4(6):241-52.
3. Petersson K, Soderstrom C, Kiani-Anaraki M, Levy G. Evaluation of the ability of thermal and electrical tests to register pulp vitality. Endod Dent Traumatol 1999; 15(3):127-31.
4. Lipton JA, Ship JA, Larach-Robinson D. Estimated prevalence and distribution of reported orofacial pain in the United States. J Am Dent Assoc 1993; 124(10):115-21.
5. Byers MR. Dental sensory receptors. Int Rev Neurobiol 1984; 25:39-94.
6. Byers MR, Narhi MV. Dental injury models: experimental tools for understanding neuroinflammatory interactions and polymodal nociceptor functions. Crit Rev Oral Biol Med 1999; 10(1):4-39.
7. Bergenholtz G, Hörsted-Bindslev P, Reit C. Textbook of endodontology. Oxford, UK: Blackwell Munksgaard; 2003.
8. Johnsen DC, Harshbarger J, Rymer HD. Quantitative assessment of neural development in human premolars. Anat Rec 1983; 205(4):421-9.
9. Nanci A, Ten Cate AR. Ten Cate's oral histology: development, structure, and function. 6th ed. St. Louis: Mosby; 2003.
10. Bender IB. Pulpal pain diagnosis - a review. J Endod 2000; 26 (3):175-9.
11. Byers MR, Dong WK. Autoradiographic location of sensory nerve endings in dentin of monkey teeth. Anat Rec 1983; 205(4):441-54.
12. Johnsen D, Johns S. Quantitation of nerve fibres in the primary and permanent canine and incisor teeth in man. Arch Oral Biol 1978; 23(9):825-9.
13. Braennstroem M, Astroem A. A study on the mechanism of pain elicited from the dentin. J Dent Res 1964; 43:619-25.
14. Andrew D, Matthews B. Displacement of the contents of dentinal tubules and sensory transduction in intradental nerves of the cat. J Physiol 2000; 529 Pt 3:791-802.
15. Narhi MV. Dentin sensitivity: a review. J Biol Buccale 1985; 13(2):75-96.
16. Narhi M, Jyvasjarvi E, Virtanen A, Huopaniemi T, Ngassapa D, Hirvonen T. Role of intradental A- and C-type nerve fibres in dental pain mechanisms. Proc Finn Dent Soc 1992; 88 Suppl 1:507-16.
17. Matthews B, Vongsavan N. Interactions between neural and hydrodynamic mechanisms in dentine and pulp. Arch Oral Biol 1994; 39 Suppl:87S-95S.
18. Pashley DH. Mechanisms of dentin sensitivity. Dent Clin North Am 1990; 34(3):449-73.
19. Vongsavan N, Matthews B. The relationship between the discharge of interdental nerves and the rate of fluid flow through dentine in the cat. Arch Oral Biol 2007; 52(7):640-7. Epub 2007 Feb 15.
20. Trowbridge HO. Pulp biology: progress during the past 25 years. Aust Endod J 2003; 29(1):5-12.
21. Trowbridge HO. Intradental sensory units: physiological and clinical aspects. J Endod 1985; 11(11):489-98.
22. Trowbridge HO, Franks M, Korostoff E, Emling R. Sensory response to thermal stimulation in human teeth. J Endod 1980; 6(1):405-12.
23. Narhi M, Jyvasjarvi E, Hirvonen T, Huopaniemi T. Activation of heat-sensitive nerve fibres in the dental pulp of the cat. Pain 1982; 14(4):317-26.
24. Linsuwanont P, Versluis A, Palamara JE, Messer HH. Thermal stimulation causes tooth deformation: a possible alternative to the hydrodynamic theory? Arch Oral Biol 2008; 53(3):261-72.
25. Pashley DH. Sensitivity of dentin to chemical stimuli. Endod Dent Traumatol 1986; 2(4):130-7.
26. Anderson DJ, Matthews B, Shelton LE. Variations in the sensitivity to osmotic stimulation of human dentine. Arch Oral Biol 1967; 12(1):43-7.
27. Narhi M, Kontturi-Narhi V, Hirvonen T, Ngassapa D. Neurophysiological mechanisms of dentin hypersensitivity. Proc Finn Dent Soc 1992; 88 Suppl 1:15-22.
28. Narhi MV, Hirvonen T. The response of dog intradental nerves to hypertonic solutions of CaCl2 and NaCl, and other stimuli, applied to exposed dentine. Arch Oral Biol 1987; 32(11):781-6.
29. Ajcharanukul O, Kraivaphan P, Wanachantararak S, Vongsavan N, Matthews B. Effects of potassium ions on dentine sensitivity in man. Arch Oral Biol 2007; 52(7):632-9.
30. Olgart L. Neural control of pulpal blood flow. Crit Rev Oral Biol Med 1996; 7(2):159-71.
31. Ahlberg KF. Dose-dependent inhibition of sensory nerve activity in the feline dental pulp by anti-inflammatory drugs. Acta Physiol Scand 1978; 102(4):434-40.
32. Olgart L, Haegerstam G, Edwall L. The effect of extracellular calcium on thermal excitability of the sensory units in the tooth of the cat. Acta Physiol Scand 1974; 91(1):116-22.
33. Torebjork HE, Hallin RG. Perceptual changes accompanying controlled preferential blocking of A and C fibre responses in intact human skin nerves. Exp Brain Res 1973; 16(3):321-32.
34. Edwall L, Kindlova M. The effect of sympathetic nerve stimulation on the rate of disappearance of tracers from various oral tissues. Acta Odontol Scand 1971; 29(4):387-400.
35. Hargreaves KM, Goodis HE, Seltzer S. Seltzer and Bender's dental pulp. Chicago: Quintessence Pub. Co. Inc; June 2002.
36. Narhi M, Virtanen A, Kuhta J, Huopaniemi T. Electrical stimulation of teeth with a pulp tester in the cat. Scand J Dent Res 1979; 87(1):32-8.
37. Mullaney TP, Howell RM, Petrich JD. Resistance of nerve fibres to pulpal necrosis. Oral Surg Oral Med Oral Pathol 1970; 30(5):690-3.
38. Cohen S, Hargreaves KM. Pathways of the pulp. 9th ed. Mosby; 2006.
39. Byers MR. Effects of inflammation on dental sensory nerves and vice versa. Proc Finn Dent Soc 1992; 88 Suppl 1:499-506.
40. Stein C. Peripheral mechanisms of opioid analgesia. Anesth Analg 1993; 76(1):182-91.
41. Olgart LM. The role of local factors in dentin and pulp in intradental pain mechanisms. J Dent Res 1985; 64 Spec No:572-8.
42. Ngassapa D, Narhi M, Hirvonen T. Effect of serotonin (5-HT) and calcitonin gene-related peptide (CGRP) on the function of intradental nerves in the dog. Proc Finn Dent Soc 1992; 88 Suppl 1:143-8.
43. Charoenlarp P, Wanachantararak S, Vongsavan N, Matthews B. Pain and the rate of dentinal fluid flow produced by hydrostatic pressure stimulation of exposed dentine in man. Arch Oral Biol 2007; 52(7):625-31.
44. Narhi M. Activation of dental pulp nerves of the cat and the dog with hydrostatic pressure. Proc Finn Dent Soc 1978; 74 Suppl 5-7:1-63.
45. Narhi M, Yamamoto H, Ngassapa D, Hirvonen T. The neurophysiological basis and the role of inflammatory reactions in dentine hypersensitivity. Arch Oral Biol 1994; 39 Suppl:23S-30S.
46. Seltzer S, Bender IB, Ziontz M. The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp. Oral Surg Oral Med Oral Pathol 1963; 16:969-77.
47. Baume LJ. Diagnosis of diseases of the pulp. Oral Surg Oral Med Oral Pathol 1970; 29(1):102-16.