Projection of non-peptidergic afferents to mouse tooth pulp

Journal of Dental Research

Volumn 91, Issue 8, 2012, Pages 777-782

  Chung, M K ^a   Jue, S S ^b   Dong, X ^c  

^a UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^b Kyung Hee University   (South Korea)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

dental pulp; immunohistochemistry; Mas related receptor MrgD; nociceptor; pain; transgenic mice

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; DIAGNOSTIC AGENT; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; LECTIN; LUMINESCENT AGENT; MRGPRD PROTEIN, MOUSE;

ANIMAL; ARTICLE; CLASSIFICATION; CYTOLOGY; GENE TARGETING; GENETICS; HISTOLOGY; INNERVATION; MECHANORECEPTOR; MECHANOTRANSDUCTION; MOUSE; NERVE ENDING; NERVE FIBER; PAIN RECEPTOR; PHYSIOLOGY; SENSORY NERVE; SENSORY NERVE CELL; TOOTH PULP; TRANSGENIC MOUSE; TRIGEMINUS GANGLION; ULTRASTRUCTURE;

AFFERENT PATHWAYS; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; DENTAL PULP; GENE KNOCK-IN TECHNIQUES; GREEN FLUORESCENT PROTEINS; LECTINS; LUMINESCENT AGENTS; MECHANORECEPTORS; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, TRANSGENIC; NERVE ENDINGS; NERVE FIBERS; NEURONS, AFFERENT; NOCICEPTORS; RECEPTORS, G-PROTEIN-COUPLED; TRIGEMINAL GANGLION;

EID: 84864133379     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034512450298     Document Type: Article

References (28)

1. Abrahamsen B, Zhao J, Asante CO, Cendan CM, Marsh S, Martinez-Barbera JP, et al. The cell and molecular basis of mechanical, cold, and inflammatory pain. Science. 2008 ; 321: 702-705
2. Alavi AM, Dubyak GR, Burnstock G. Immunohistochemical evidence for ATP receptors in human dental pulp. J Dent Res. 2001 ; 80: 476-483 (Pubitemid 32378956)
3. Brannström M. The hydrodynamic theory of dentinal pain: sensation in preparations, caries, and the dentinal crack syndrome. J Endod. 1986 ; 12: 453-457
4. Byers MR. Terminal arborization of individual sensory axons in dentin and pulp of rat molars. Brain Res. 1985 ; 345: 181-185 (Pubitemid 16217931)
5. Byers MR, Närhi MV. Dental injury models: experimental tools for understanding neuroinflammatory interactions and polymodal nociceptor functions. Crit Rev Oral Biol Med. 1999 ; 10: 4-39 (Pubitemid 29510045)
6. Cavanaugh DJ, Lee H, Lo L, Shields SD, Zylka MJ, Basbaum AI, et al. Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci USA. 2009 ; 106: 9075-9080
7. Chung MK, Lee J, Duraes G, Ro JY. Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal ganglia. J Dent Res. 2011 ; 90: 1103-1107
8. Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 ; 106: 619-632 (Pubitemid 32879323)
9. Fried K, Arvidsson J, Robertson B, Brodin E, Theodorsson E. Combined retrograde tracing and enzyme/immunohistochemistry of trigeminal ganglion cell bodies innervating tooth pulps in the rat. Neuroscience. 1989 ; 33: 101-109 (Pubitemid 20032979)
10. Fried K, Sessle BJ, Devor M. The paradox of pain from tooth pulp: low-threshold "algoneurons"?. Pain. 2011 ; 152: 2685-2689
11. Gibbs JL, Melnyk JL, Basbaum AI. Differential TRPV1 and TRPV2 channel expression in dental pulp. J Dent Res. 2011 ; 90: 765-770
12. Hakumaki MO, Närhi MV. Effect of intrapulpal pressure stimulation on the activity of sensory nerves of dental pulp. Acta Physiol Scand. 1973 ; 88: 584-586
13. Henry MA, Hargreaves KM. Peripheral mechanisms of odontogenic pain. Dent Clin North Am. 2007 ; 51: 19-44 (Pubitemid 44932157)
14. Hermanstyne TO, Markowitz K, Fan L, Gold MS. Mechanotransducers in rat pulpal afferents. J Dent Res. 2008 ; 87: 834-838
15. Heyeraas KJ, Berggreen E. Interstitial fluid pressure in normal and inflamed pulp. Crit Rev Oral Biol Med. 1999 ; 10: 328-336 (Pubitemid 29451178)
16. Hunt SP, Mantyh PW. The molecular dynamics of pain control. Nat Rev Neurosci. 2001 ; 2: 83-91 (Pubitemid 33673362)
17. Ichikawa H, Sugimoto T. The co-expression of P2X3 receptor with VR1 and VRL-1 in the rat trigeminal ganglion. Brain Res. 2004 ; 998: 130-135 (Pubitemid 38077133)
18. Ichikawa H, Matsuo S, Terayama R, Yamaai T, Sugimoto T. Aspartate-immunoreactive primary sensory neurons in the mouse trigeminal ganglion. Brain Res. 2006 ; 1082: 67-72
19. Kim HY, Chung G, Jo HJ, Kim YS, Bae YC, Jung SJ, et al J Dent Res. 771- ; 2011: 776.
20. Kvinnsland IH, Luukko K, Fristad I, Kettunen P, Jackson DL, Fjeld K, et al. Glial cell line-derived neurotrophic factor (GDNF) from adult rat tooth serves a distinct population of large-sized trigeminal neurons. Eur J Neurosci. 2004 ; 19: 2089-2098 (Pubitemid 38582198)
21. Liu Q, Vrontou S, Rice FL, Zylka MJ, Dong X, Anderson DJ. Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch. Nat Neurosci. 2007 ; 10: 946-948 (Pubitemid 47185205)
22. Magloire H, Maurin JC, Couble ML, Shibukawa Y, Tsumura M, Thivichon-Prince B, et al. Topical review. Dental pain and odontoblasts: facts and hypotheses. J Orofac Pain. 2010 ; 24: 335-349
23. Pan Y, Wheeler EF, Bernanke JM, Yang H, Naftel JP. A model experimental system for monitoring changes in sensory neuron phenotype evoked by tooth injury. J Neurosci Methods. 2003 ; 126: 99-109 (Pubitemid 36683060)
24. Park CK, Kim MS, Fang Z, Li HY, Jung SJ, Choi SY, et al. Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: implication for tooth pain. J Biol Chem. 2006 ; 281: 17304-17311
25. Rau KK, McIlwrath SL, Wang H, Lawson JJ, Jankowski MP, Zylka MJ, et al. Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors. J Neurosci. 2009 ; 29: 8612-8619
26. Wang H, Zylka MJ. Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons. J Neurosci. 2009 ; 29: 13202-13209
27. YangHBernankeJMPanYNaftelJP (2002) Expression of RET immunoreactivity by pulpal afferent neurons of the rat [abstract]. J Dent Res82(Spec Iss A):291. http://iadr.confex.com/iadr/2002SanDiego/techprogram/abstract-18363.htm
28. Zylka MJ, Rice FL, Anderson DJ. Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron. 2005 ; 45: 17-25 (Pubitemid 40075346)