Adult rat odontoblasts lack noxious thermal sensitivity

Journal of Dental Research

Volumn 88, Issue 4, 2009, Pages 328-332

  Yeon, K Y ^a   Chung, G ^a   Shin, M S ^a   Jung, S J ^b   Kim, J S ^a   Oh, S B ^a  

^a Seoul National University   (South Korea)

^b Kangwon National Universtiy   (South Korea)

Author keywords

Dentin hypersensitivity; Odontoblast; TRP

Indexed keywords

MESSENGER RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPV1 RECEPTOR; VANILLOID RECEPTOR;

ANIMAL; ARTICLE; CELL CULTURE; CYTOLOGY; DENTIN SENSITIVITY; GENETICS; INCISOR; METABOLISM; NOCICEPTIVE RECEPTOR; ODONTOBLAST; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TEMPERATURE SENSE; TOOTH PULP; TRIGEMINUS GANGLION;

ANIMALS; CELLS, CULTURED; DENTAL PULP; DENTIN SENSITIVITY; INCISOR; NOCICEPTORS; ODONTOBLASTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TEMPERATURE SENSE; TRIGEMINAL GANGLION; TRPC CATION CHANNELS; TRPV CATION CHANNELS;

EID: 66149093116     PISSN: 00220345     EISSN: None     Source Type: Journal    
DOI: 10.1177/0022034509334100     Document Type: Article

References (25)

1. Allard B, Magloire H, Couble ML, Maurin JC, Bleicher F (2006). Voltage-gated sodium channels confer excitability to human odontoblasts: possible role in tooth pain transmission. J Biol Chem 281:29002-29010. (Pubitemid 44507044)
2. Ambudkar IS (2007). TRPC1: a core component of store-operated calcium channels. Biochem Soc Trans 35(Pt 1):96-100.
3. Andrew D, Matthews B (2000). Displacement of the contents of dentinal tubules and sensory transduction in intradental nerves of the cat. J Physiol 529(Pt 3):791-802. (Pubitemid 32051078)
4. Brännström M, Aström A (1972). The hydrodynamics of the dentine; its possible relationship to dentinal pain. Int Dent J 22:219-227.
5. Brännström M, Lindén LA, Aström A (1967). The hydrodynamics of the dental tubule and of pulp fluid. A discussion of its significance in relation to dentinal sensitivity. Caries Res 1:310-317.
6. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824. (Pubitemid 27462969)
7. Guo L, Berry JE, Somerman MJ, Davidson RM (2000). A novel method to isolate odontoblasts from rat incisor. Calcif Tissue Int 66:212-216. (Pubitemid 30091763)
8. Kim HY, Park CK, Cho IH, Jung SJ, Kim JS, Oh SB (2008). Differential changes in TRPV1 expression after trigeminal sensory nerve injury. J Pain 9:280-288.
9. Macpherson LJ, Hwang SW, Miyamoto T, Dubin AE, Patapoutian A, Story GM (2006). More than cool: promiscuous relationships of menthol and other sensory compounds. Mol Cell Neurosci 32:335-343. (Pubitemid 44163229)
10. Magloire H, Lesage F, Couble ML, Lazdunski M, Bleicher F (2003). Expression and localization of TREK-1 K+ channels in human odontoblasts. J Dent Res 82:542-545. (Pubitemid 41756887)
11. Magloire H, Couble ML, Romeas A, Bleicher F (2004). Odontoblast primary cilia: facts and hypotheses. Cell Biol Int 28:93-99. (Pubitemid 38258235)
12. Magloire H, Allard B, Couble ML, Maurin JC, Bleicher F (2008). Mechanosensitive ion channels in odontoblasts. In: Mechanosensitive ion channels. Kamkin A, Kiseleva I, editors. The Netherlands: Springer, pp. 147-156.
13. Maingret F, Patel AJ, Lesage F, Lazdunski M, Honore E (1999). Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel. J Biol Chem 274:26691-26696. (Pubitemid 129520183)
14. Malone AM, Anderson CT, Tummala P, Kwon RY, Johnston TR, Stearns T, et al. (2007). Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proc Natl Acad Sci USA 104:13325-13330. (Pubitemid 47293944)
15. Maroto R, Raso A, Wood TG, Kurosky A, Martinac B, Hamill OP (2005). TRPC1 forms the stretch-activated cation channel in vertebrate cells. Nat Cell Biol 7:179-185. (Pubitemid 40268133)
16. McKemy DD, Neuhausser WM, Julius D (2002). Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416:52-58.
17. Millard PJ, Gross D, Webb WW, Fewtrell C (1988). Imaging asynchronous changes in intracellular Ca2+ in individual stimulated tumor mast cells. Proc Natl Acad Sci USA 85:1854-1858. (Pubitemid 24315782)
18. Okumura R, Shima K, Muramatsu T, Nakagawa K, Shimono M, Suzuki T, et al. (2005). The odontoblast as a sensory receptor cell? The expression of TRPV1 (VR-1) channels. Arch Histol Cytol 68:251-257. (Pubitemid 43274020)
19. Park CK, Kim MS, Fang Z, Li HY, Jung SJ, Choi SY, et al. (2006). Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: implication for tooth pain. J Biol Chem 281:17304-17311. (Pubitemid 43909539)
20. Patapoutian A, Peier AM, Story GM, Viswanath V (2003). ThermoTRP channels and beyond: mechanisms of temperature sensation. Nat Rev Neurosci 4:529-539; erratum in Nat Rev Neurosci 4:691, 2003. (Pubitemid 37280164)
21. Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, et al. (2002). A TRP channel that senses cold stimuli and menthol. Cell 108:705-715. (Pubitemid 34241429)
22. Ritchie HH, Hou H, Veis A, Butler WT (1994). Cloning and sequence determination of rat dentin sialoprotein, a novel dentin protein. J Biol Chem 269:3698-3702. (Pubitemid 24237697)
23. Scholz J, Woolf CJ (2002). Can we conquer pain? Nat Neurosci 5(Suppl):1062-1067. (Pubitemid 35247200)
24. Shibukawa Y, Suzuki T (2003). Ca2+ signaling mediated by IP3-dependent Ca2+ releasing and store-operated Ca2+ channels in rat odontoblasts. J Bone Miner Res 18:30-38.
25. Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, et al. (2003). ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112:819-829. (Pubitemid 36378884)