-
1
-
-
61649100307
-
The FGF family: biology, pathophysiology and therapy
-
10.1038/nrd2792, 19247306
-
Beenken A, Mohammadi M. The FGF family: biology, pathophysiology and therapy. Nat Rev Drug Discov 2009, 8:235-253. 10.1038/nrd2792, 19247306.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 235-253
-
-
Beenken, A.1
Mohammadi, M.2
-
2
-
-
34249686631
-
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21
-
10.1016/j.cmet.2007.05.003, 17550777
-
Inagaki T, Dutchak P, Zhao G, Ding X, Gautron L, Parameswara V, Li Y, Goetz R, Mohammadi M, Esser V, Elmquist JK, Gerard RD, Burgess SC, Hammer RE, Mangelsdorf DJ, Kliewer SA. Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. Cell Metab 2007, 5:415-425. 10.1016/j.cmet.2007.05.003, 17550777.
-
(2007)
Cell Metab
, vol.5
, pp. 415-425
-
-
Inagaki, T.1
Dutchak, P.2
Zhao, G.3
Ding, X.4
Gautron, L.5
Parameswara, V.6
Li, Y.7
Goetz, R.8
Mohammadi, M.9
Esser, V.10
Elmquist, J.K.11
Gerard, R.D.12
Burgess, S.C.13
Hammer, R.E.14
Mangelsdorf, D.J.15
Kliewer, S.A.16
-
3
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
10.1172/JCI23606, 1088017, 15902306
-
Kharitonenkov A, Shiyanova TL, Koester A, Ford AM, Micanovic R, Galbreath EJ, Sandusky GE, Hammond LJ, Moyers JS, Owens RA, Gromada J, Brozinick JT, Hawkins ED, Wroblewski VJ, Li DS, Mehrbod F, Jaskunas SR, Shanafelt AB. FGF-21 as a novel metabolic regulator. J Clin Invest 2005, 115:1627-1635. 10.1172/JCI23606, 1088017, 15902306.
-
(2005)
J Clin Invest
, vol.115
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
Sandusky, G.E.7
Hammond, L.J.8
Moyers, J.S.9
Owens, R.A.10
Gromada, J.11
Brozinick, J.T.12
Hawkins, E.D.13
Wroblewski, V.J.14
Li, D.S.15
Mehrbod, F.16
Jaskunas, S.R.17
Shanafelt, A.B.18
-
4
-
-
80053409251
-
Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes
-
10.1074/jbc.M111.285965, 3186378, 21849508
-
Chen W, Hoo RL, Konishi M, Itoh N, Lee PC, Ye HY, Lam KS, Xu A. Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes. J Biol Chem 2011, 286:34559-34566. 10.1074/jbc.M111.285965, 3186378, 21849508.
-
(2011)
J Biol Chem
, vol.286
, pp. 34559-34566
-
-
Chen, W.1
Hoo, R.L.2
Konishi, M.3
Itoh, N.4
Lee, P.C.5
Ye, H.Y.6
Lam, K.S.7
Xu, A.8
-
5
-
-
84870359606
-
Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the betaKlotho/FGFR1c Receptor Complex
-
10.1126/scitranslmed.3004690, 23197570
-
Foltz IN, Hu S, King C, Wu X, Yang C, Wang W, Weiszmann J, Stevens J, Chen JS, Nuanmanee N, Gupte J, Komorowski R, Sekirov L, Hager T, Arora T, Ge H, Baribault H, Wang F, Sheng J, Karow M, Wang M, Luo Y, McKeehan WL, Wang Z, Veniant MM, Li Y. Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the betaKlotho/FGFR1c Receptor Complex. Sci Transl Med 2012, 4:162ra153. 10.1126/scitranslmed.3004690, 23197570.
-
(2012)
Sci Transl Med
, vol.4
-
-
Foltz, I.N.1
Hu, S.2
King, C.3
Wu, X.4
Yang, C.5
Wang, W.6
Weiszmann, J.7
Stevens, J.8
Chen, J.S.9
Nuanmanee, N.10
Gupte, J.11
Komorowski, R.12
Sekirov, L.13
Hager, T.14
Arora, T.15
Ge, H.16
Baribault, H.17
Wang, F.18
Sheng, J.19
Karow, M.20
Wang, M.21
Luo, Y.22
McKeehan, W.L.23
Wang, Z.24
Veniant, M.M.25
Li, Y.26
more..
-
6
-
-
34848869695
-
Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
-
10.1074/jbc.M704165200, 2496965, 17623664
-
Kurosu H, Choi M, Ogawa Y, Dickson AS, Goetz R, Eliseenkova AV, Mohammadi M, Rosenblatt KP, Kliewer SA, Kuro-o M. Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J Biol Chem 2007, 282:26687-26695. 10.1074/jbc.M704165200, 2496965, 17623664.
-
(2007)
J Biol Chem
, vol.282
, pp. 26687-26695
-
-
Kurosu, H.1
Choi, M.2
Ogawa, Y.3
Dickson, A.S.4
Goetz, R.5
Eliseenkova, A.V.6
Mohammadi, M.7
Rosenblatt, K.P.8
Kliewer, S.A.9
Kuro-o, M.10
-
7
-
-
84863637593
-
FGF21 promotes metabolic homeostasis via white adipose and leptin in mice
-
10.1371/journal.pone.0040164, 3391219, 22792234
-
Veniant MM, Hale C, Helmering J, Chen MM, Stanislaus S, Busby J, Vonderfecht S, Xu J, Lloyd DJ. FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. PLoS One 2012, 7:e40164. 10.1371/journal.pone.0040164, 3391219, 22792234.
-
(2012)
PLoS One
, vol.7
-
-
Veniant, M.M.1
Hale, C.2
Helmering, J.3
Chen, M.M.4
Stanislaus, S.5
Busby, J.6
Vonderfecht, S.7
Xu, J.8
Lloyd, D.J.9
-
8
-
-
84863338708
-
Differential Specificity of Endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in Complex with KLB
-
10.1371/journal.pone.0033870, 3307775, 22442730
-
Yang C, Jin C, Li X, Wang F, McKeehan WL, Luo Y. Differential Specificity of Endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in Complex with KLB. PLoS One 2012, 7:e33870. 10.1371/journal.pone.0033870, 3307775, 22442730.
-
(2012)
PLoS One
, vol.7
-
-
Yang, C.1
Jin, C.2
Li, X.3
Wang, F.4
McKeehan, W.L.5
Luo, Y.6
-
9
-
-
84867898251
-
Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress
-
Yang C, Wang C, Ye M, Jin C, He W, Wang F, McKeehan WL, Luo Y. Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress. Nutr Metab (Lond) 2012, 9:94.
-
(2012)
Nutr Metab (Lond)
, vol.9
, pp. 94
-
-
Yang, C.1
Wang, C.2
Ye, M.3
Jin, C.4
He, W.5
Wang, F.6
McKeehan, W.L.7
Luo, Y.8
-
10
-
-
84871381674
-
The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue
-
Adams AC, Chaofeng Y, Tamer C, Cheng CC, Gimeno RE, Yongde L, Alexei K. The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue. Molecular Metabolism 2012, http://download.journals.elsevierhealth.com/pdfs/journals/2212-8778/PIIS2212877812000166.pdf.
-
(2012)
Molecular Metabolism
-
-
Adams, A.C.1
Chaofeng, Y.2
Tamer, C.3
Cheng, C.C.4
Gimeno, R.E.5
Yongde, L.6
Alexei, K.7
-
11
-
-
69249093921
-
Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity
-
10.1210/en.2009-0221, 2736088, 19470704
-
Berglund ED, Li CY, Bina HA, Lynes SE, Michael MD, Shanafelt AB, Kharitonenkov A, Wasserman DH. Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity. Endocrinology 2009, 150:4084-4093. 10.1210/en.2009-0221, 2736088, 19470704.
-
(2009)
Endocrinology
, vol.150
, pp. 4084-4093
-
-
Berglund, E.D.1
Li, C.Y.2
Bina, H.A.3
Lynes, S.E.4
Michael, M.D.5
Shanafelt, A.B.6
Kharitonenkov, A.7
Wasserman, D.H.8
-
12
-
-
57349098220
-
Fibroblast growth factor 21 corrects obesity in mice
-
10.1210/en.2008-0816, 18687777
-
Coskun T, Bina HA, Schneider MA, Dunbar JD, Hu CC, Chen Y, Moller DE, Kharitonenkov A. Fibroblast growth factor 21 corrects obesity in mice. Endocrinology 2008, 149:6018-6027. 10.1210/en.2008-0816, 18687777.
-
(2008)
Endocrinology
, vol.149
, pp. 6018-6027
-
-
Coskun, T.1
Bina, H.A.2
Schneider, M.A.3
Dunbar, J.D.4
Hu, C.C.5
Chen, Y.6
Moller, D.E.7
Kharitonenkov, A.8
-
13
-
-
33846418834
-
The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21
-
Kharitonenkov A, Wroblewski VJ, Koester A, Chen YF, Clutinger CK, Tigno XT, Hansen BC, Shanafelt AB, Etgen GJ. The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21. Endocrinology 2007, 148:774-781.
-
(2007)
Endocrinology
, vol.148
, pp. 774-781
-
-
Kharitonenkov, A.1
Wroblewski, V.J.2
Koester, A.3
Chen, Y.F.4
Clutinger, C.K.5
Tigno, X.T.6
Hansen, B.C.7
Shanafelt, A.B.8
Etgen, G.J.9
-
14
-
-
70349324370
-
Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver
-
10.1210/en.2009-0119, 19589869
-
Hotta Y, Nakamura H, Konishi M, Murata Y, Takagi H, Matsumura S, Inoue K, Fushiki T, Itoh N. Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver. Endocrinology 2009, 150:4625-4633. 10.1210/en.2009-0119, 19589869.
-
(2009)
Endocrinology
, vol.150
, pp. 4625-4633
-
-
Hotta, Y.1
Nakamura, H.2
Konishi, M.3
Murata, Y.4
Takagi, H.5
Matsumura, S.6
Inoue, K.7
Fushiki, T.8
Itoh, N.9
-
15
-
-
58349115748
-
The Klotho gene family as a regulator of endocrine fibroblast growth factors
-
10.1016/j.mce.2008.10.052, 19063940
-
Kurosu H, Kuro OM. The Klotho gene family as a regulator of endocrine fibroblast growth factors. Mol Cell Endocrinol 2009, 299:72-78. 10.1016/j.mce.2008.10.052, 19063940.
-
(2009)
Mol Cell Endocrinol
, vol.299
, pp. 72-78
-
-
Kurosu, H.1
Kuro, O.M.2
-
16
-
-
34249711964
-
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states
-
10.1016/j.cmet.2007.05.002, 17550778
-
Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E. Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metab 2007, 5:426-437. 10.1016/j.cmet.2007.05.002, 17550778.
-
(2007)
Cell Metab
, vol.5
, pp. 426-437
-
-
Badman, M.K.1
Pissios, P.2
Kennedy, A.R.3
Koukos, G.4
Flier, J.S.5
Maratos-Flier, E.6
-
17
-
-
76049093949
-
PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis
-
10.1073/pnas.0912533106, 2799738, 20018698
-
Estall JL, Ruas JL, Choi CS, Laznik D, Badman M, Maratos-Flier E, Shulman GI, Spiegelman BM. PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis. Proc Natl Acad Sci USA 2009, 106:22510-22515. 10.1073/pnas.0912533106, 2799738, 20018698.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 22510-22515
-
-
Estall, J.L.1
Ruas, J.L.2
Choi, C.S.3
Laznik, D.4
Badman, M.5
Maratos-Flier, E.6
Shulman, G.I.7
Spiegelman, B.M.8
-
18
-
-
78049297991
-
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
-
10.2337/db10-0193, 2963536, 20682689
-
Fisher FM, Chui PC, Antonellis PJ, Bina HA, Kharitonenkov A, Flier JS, Maratos-Flier E. Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes 2010, 59:2781-2789. 10.2337/db10-0193, 2963536, 20682689.
-
(2010)
Diabetes
, vol.59
, pp. 2781-2789
-
-
Fisher, F.M.1
Chui, P.C.2
Antonellis, P.J.3
Bina, H.A.4
Kharitonenkov, A.5
Flier, J.S.6
Maratos-Flier, E.7
-
19
-
-
34447265235
-
PPARalpha is a key regulator of hepatic FGF21
-
10.1016/j.bbrc.2007.06.068, 17601491
-
Lundasen T, Hunt MC, Nilsson LM, Sanyal S, Angelin B, Alexson SE, Rudling M. PPARalpha is a key regulator of hepatic FGF21. Biochem Biophys Res Commun 2007, 360:437-440. 10.1016/j.bbrc.2007.06.068, 17601491.
-
(2007)
Biochem Biophys Res Commun
, vol.360
, pp. 437-440
-
-
Lundasen, T.1
Hunt, M.C.2
Nilsson, L.M.3
Sanyal, S.4
Angelin, B.5
Alexson, S.E.6
Rudling, M.7
-
20
-
-
67650263853
-
Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21
-
10.2337/db08-1775, 2699854, 19401423
-
Mai K, Andres J, Biedasek K, Weicht J, Bobbert T, Sabath M, Meinus S, Reinecke F, Mohlig M, Weickert MO, Clemenz M, Pfeiffer AF, Kintscher U, Spuler S, Spranger J. Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21. Diabetes 2009, 58:1532-1538. 10.2337/db08-1775, 2699854, 19401423.
-
(2009)
Diabetes
, vol.58
, pp. 1532-1538
-
-
Mai, K.1
Andres, J.2
Biedasek, K.3
Weicht, J.4
Bobbert, T.5
Sabath, M.6
Meinus, S.7
Reinecke, F.8
Mohlig, M.9
Weickert, M.O.10
Clemenz, M.11
Pfeiffer, A.F.12
Kintscher, U.13
Spuler, S.14
Spranger, J.15
-
21
-
-
48349146527
-
Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
-
10.2337/db07-1476, 18252893
-
Zhang X, Yeung DC, Karpisek M, Stejskal D, Zhou ZG, Liu F, Wong RL, Chow WS, Tso AW, Lam KS, Xu A. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes 2008, 57:1246-1253. 10.2337/db07-1476, 18252893.
-
(2008)
Diabetes
, vol.57
, pp. 1246-1253
-
-
Zhang, X.1
Yeung, D.C.2
Karpisek, M.3
Stejskal, D.4
Zhou, Z.G.5
Liu, F.6
Wong, R.L.7
Chow, W.S.8
Tso, A.W.9
Lam, K.S.10
Xu, A.11
-
22
-
-
80052036925
-
Time-imposed daily restricted feeding induces rhythmic expression of Fgf21 in white adipose tissue of mice
-
10.1016/j.bbrc.2011.07.125, 21835167
-
Oishi K, Konishi M, Murata Y, Itoh N. Time-imposed daily restricted feeding induces rhythmic expression of Fgf21 in white adipose tissue of mice. Biochem Biophys Res Commun 2011, 412:396-400. 10.1016/j.bbrc.2011.07.125, 21835167.
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 396-400
-
-
Oishi, K.1
Konishi, M.2
Murata, Y.3
Itoh, N.4
-
23
-
-
79960334459
-
Thiazolidinediones are potent inducers of fibroblast growth factor 21 expression in the liver
-
10.1248/bpb.34.1120, 21720023
-
Oishi K, Tomita T. Thiazolidinediones are potent inducers of fibroblast growth factor 21 expression in the liver. Biol Pharm Bull 2011, 34:1120-1121. 10.1248/bpb.34.1120, 21720023.
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 1120-1121
-
-
Oishi, K.1
Tomita, T.2
-
24
-
-
77955474305
-
Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease
-
10.1053/j.gastro.2010.04.054, 20451522
-
Dushay J, Chui PC, Gopalakrishnan GS, Varela-Rey M, Crawley M, Fisher FM, Badman MK, Martinez-Chantar ML, Maratos-Flier E. Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease. Gastroenterology 2010, 139:456-463. 10.1053/j.gastro.2010.04.054, 20451522.
-
(2010)
Gastroenterology
, vol.139
, pp. 456-463
-
-
Dushay, J.1
Chui, P.C.2
Gopalakrishnan, G.S.3
Varela-Rey, M.4
Crawley, M.5
Fisher, F.M.6
Badman, M.K.7
Martinez-Chantar, M.L.8
Maratos-Flier, E.9
-
25
-
-
79151469687
-
Lipotoxicity and steatohepatitis in an overfed mouse model for non-alcoholic fatty liver disease
-
Gaemers IC, Stallen JM, Kunne C, Wallner C, van Werven J, Nederveen A, Lamers WH. Lipotoxicity and steatohepatitis in an overfed mouse model for non-alcoholic fatty liver disease. Biochim Biophys Acta 1812, 2011:447-458.
-
(1812)
Biochim Biophys Acta
, vol.2011
, pp. 447-458
-
-
Gaemers, I.C.1
Stallen, J.M.2
Kunne, C.3
Wallner, C.4
van Werven, J.5
Nederveen, A.6
Lamers, W.H.7
-
26
-
-
79960564639
-
Serum FGF21 levels are increased in newly diagnosed type 2 diabetes with nonalcoholic fatty liver disease and associated with hsCRP levels independently
-
10.1016/j.diabres.2011.02.034, 21596453
-
Li X, Fan X, Ren F, Zhang Y, Shen C, Ren G, Sun J, Zhang N, Wang W, Ning G, Yang J. Serum FGF21 levels are increased in newly diagnosed type 2 diabetes with nonalcoholic fatty liver disease and associated with hsCRP levels independently. Diabetes Res Clin Pract 2011, 93:10-16. 10.1016/j.diabres.2011.02.034, 21596453.
-
(2011)
Diabetes Res Clin Pract
, vol.93
, pp. 10-16
-
-
Li, X.1
Fan, X.2
Ren, F.3
Zhang, Y.4
Shen, C.5
Ren, G.6
Sun, J.7
Zhang, N.8
Wang, W.9
Ning, G.10
Yang, J.11
-
27
-
-
78349310229
-
Serum FGF21 levels are elevated in association with lipodystrophy, insulin resistance and biomarkers of liver injury in HIV-1-infected patients
-
10.1097/QAD.0b013e3283400088, 20935553
-
Domingo P, Gallego-Escuredo JM, Domingo JC, Gutierrez Mdel M, Mateo MG, Fernandez I, Vidal F, Giralt M, Villarroya F. Serum FGF21 levels are elevated in association with lipodystrophy, insulin resistance and biomarkers of liver injury in HIV-1-infected patients. AIDS 2010, 24:2629-2637. 10.1097/QAD.0b013e3283400088, 20935553.
-
(2010)
AIDS
, vol.24
, pp. 2629-2637
-
-
Domingo, P.1
Gallego-Escuredo, J.M.2
Domingo, J.C.3
Gutierrez Mdel, M.4
Mateo, M.G.5
Fernandez, I.6
Vidal, F.7
Giralt, M.8
Villarroya, F.9
-
28
-
-
84876993606
-
Cholesterol Metabolism Altered and FGF21 Levels High After Pediatric Liver Transplantation Despite Normal Serum Lipids
-
Epub ahead of print
-
Kosola S, Lampela H, Gylling H, Jalanko H, Nissinen MJ, Lauronen J, Makisalo H, Vaaralahti K, Miettinen TA, Raivio T, Pakarinen MP. Cholesterol Metabolism Altered and FGF21 Levels High After Pediatric Liver Transplantation Despite Normal Serum Lipids. Am J Transplant Epub ahead of print.
-
Am J Transplant
-
-
Kosola, S.1
Lampela, H.2
Gylling, H.3
Jalanko, H.4
Nissinen, M.J.5
Lauronen, J.6
Makisalo, H.7
Vaaralahti, K.8
Miettinen, T.A.9
Raivio, T.10
Pakarinen, M.P.11
-
29
-
-
77956244443
-
Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia
-
10.1074/jbc.M110.134023, 2930685, 20573950
-
Haeusler RA, Han S, Accili D. Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia. J Biol Chem 2010, 285:26861-26868. 10.1074/jbc.M110.134023, 2930685, 20573950.
-
(2010)
J Biol Chem
, vol.285
, pp. 26861-26868
-
-
Haeusler, R.A.1
Han, S.2
Accili, D.3
-
30
-
-
67649641767
-
Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function
-
Oka S, Yoshihara E, Bizen-Abe A, Liu W, Watanabe M, Yodoi J, Masutani H. Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function. Endocrinology 2009, 150:1225-1234.
-
(2009)
Endocrinology
, vol.150
, pp. 1225-1234
-
-
Oka, S.1
Yoshihara, E.2
Bizen-Abe, A.3
Liu, W.4
Watanabe, M.5
Yodoi, J.6
Masutani, H.7
-
31
-
-
77949508276
-
Diminished diet-induced hyperglycemia and dyslipidemia and enhanced expression of PPARalpha and FGF21 in mice with hepatic ablation of brain-derived neurotropic factor
-
Teillon S, Calderon GA, Rios M. Diminished diet-induced hyperglycemia and dyslipidemia and enhanced expression of PPARalpha and FGF21 in mice with hepatic ablation of brain-derived neurotropic factor. J Endocrinol 2011, 205:37-47.
-
(2011)
J Endocrinol
, vol.205
, pp. 37-47
-
-
Teillon, S.1
Calderon, G.A.2
Rios, M.3
-
32
-
-
77952952816
-
Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet
-
10.1016/j.taap.2010.03.016, 3180859, 20350562
-
Zhang YK, Yeager RL, Tanaka Y, Klaassen CD. Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet. Toxicol Appl Pharmacol 2010, 245:326-334. 10.1016/j.taap.2010.03.016, 3180859, 20350562.
-
(2010)
Toxicol Appl Pharmacol
, vol.245
, pp. 326-334
-
-
Zhang, Y.K.1
Yeager, R.L.2
Tanaka, Y.3
Klaassen, C.D.4
-
33
-
-
84876981746
-
Ablation of gp78 in Liver Improves Hyperlipidemia and Insulin Resistance by Inhibiting SREBP to Decrease Lipid Biosynthesis
-
Epub ahead of print
-
Liu TF, Tang JJ, Li PS, Shen Y, Li JG, Miao HH, Li BL, Song BL. Ablation of gp78 in Liver Improves Hyperlipidemia and Insulin Resistance by Inhibiting SREBP to Decrease Lipid Biosynthesis. Cell Metab Epub ahead of print.
-
Cell Metab
-
-
Liu, T.F.1
Tang, J.J.2
Li, P.S.3
Shen, Y.4
Li, J.G.5
Miao, H.H.6
Li, B.L.7
Song, B.L.8
-
34
-
-
84872057896
-
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
-
Kim KH, Jeong YT, Oh H, Kim SH, Cho JM, Kim YN, Kim SS, Kim Do H, Hur KY, Kim HK, Ko T, Han J, Kim HL, Kim J, Back SH, Komatsu M, Chen H, Chan DC, Konishi M, Itoh N, Choi CS, Lee MS. Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med 2013, 19:83-92.
-
(2013)
Nat Med
, vol.19
, pp. 83-92
-
-
Kim, K.H.1
Jeong, Y.T.2
Oh, H.3
Kim, S.H.4
Cho, J.M.5
Kim, Y.N.6
Kim, S.S.7
Kim Do, H.8
Hur, K.Y.9
Kim, H.K.10
Ko, T.11
Han, J.12
Kim, H.L.13
Kim, J.14
Back, S.H.15
Komatsu, M.16
Chen, H.17
Chan, D.C.18
Konishi, M.19
Itoh, N.20
Choi, C.S.21
Lee, M.S.22
more..
-
35
-
-
84874664386
-
Fibroblast growth factor 21 is induced by endoplasmic reticulum stress
-
10.1016/j.biochi.2012.10.019, 23123503
-
Schaap FG, Kremer AE, Lamers WH, Jansen PL, Gaemers IC. Fibroblast growth factor 21 is induced by endoplasmic reticulum stress. Biochimie 2013, 95:692-699. 10.1016/j.biochi.2012.10.019, 23123503.
-
(2013)
Biochimie
, vol.95
, pp. 692-699
-
-
Schaap, F.G.1
Kremer, A.E.2
Lamers, W.H.3
Jansen, P.L.4
Gaemers, I.C.5
-
36
-
-
80051667626
-
FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study
-
10.1016/S1474-4422(11)70155-7, 21820356
-
Suomalainen A, Elo JM, Pietilainen KH, Hakonen AH, Sevastianova K, Korpela M, Isohanni P, Marjavaara SK, Tyni T, Kiuru-Enari S, Pihko H, Darin N, Ounap K, Kluijtmans LA, Paetau A, Buzkova J, Bindoff LA, Annunen-Rasila J, Uusimaa J, Rissanen A, Yki-Jarvinen H, Hirano M, Tulinius M, Smeitink J, Tyynismaa H. FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study. Lancet Neurol 2011, 10:806-818. 10.1016/S1474-4422(11)70155-7, 21820356.
-
(2011)
Lancet Neurol
, vol.10
, pp. 806-818
-
-
Suomalainen, A.1
Elo, J.M.2
Pietilainen, K.H.3
Hakonen, A.H.4
Sevastianova, K.5
Korpela, M.6
Isohanni, P.7
Marjavaara, S.K.8
Tyni, T.9
Kiuru-Enari, S.10
Pihko, H.11
Darin, N.12
Ounap, K.13
Kluijtmans, L.A.14
Paetau, A.15
Buzkova, J.16
Bindoff, L.A.17
Annunen-Rasila, J.18
Uusimaa, J.19
Rissanen, A.20
Yki-Jarvinen, H.21
Hirano, M.22
Tulinius, M.23
Smeitink, J.24
Tyynismaa, H.25
more..
-
37
-
-
77957743736
-
Mitochondrial myopathy induces a starvation-like response
-
10.1093/hmg/ddq310, 20656789
-
Tyynismaa H, Carroll CJ, Raimundo N, Ahola-Erkkila S, Wenz T, Ruhanen H, Guse K, Hemminki A, Peltola-Mjosund KE, Tulkki V, Oresic M, Moraes CT, Pietilainen K, Hovatta I, Suomalainen A. Mitochondrial myopathy induces a starvation-like response. Hum Mol Genet 2010, 19:3948-3958. 10.1093/hmg/ddq310, 20656789.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3948-3958
-
-
Tyynismaa, H.1
Carroll, C.J.2
Raimundo, N.3
Ahola-Erkkila, S.4
Wenz, T.5
Ruhanen, H.6
Guse, K.7
Hemminki, A.8
Peltola-Mjosund, K.E.9
Tulkki, V.10
Oresic, M.11
Moraes, C.T.12
Pietilainen, K.13
Hovatta, I.14
Suomalainen, A.15
-
38
-
-
79953886306
-
Thermogenic activation induces FGF21 expression and release in brown adipose tissue
-
10.1074/jbc.M110.215889, 3075644, 21317437
-
Hondares E, Iglesias R, Giralt A, Gonzalez FJ, Giralt M, Mampel T, Villarroya F. Thermogenic activation induces FGF21 expression and release in brown adipose tissue. J Biol Chem 2011, 286:12983-12990. 10.1074/jbc.M110.215889, 3075644, 21317437.
-
(2011)
J Biol Chem
, vol.286
, pp. 12983-12990
-
-
Hondares, E.1
Iglesias, R.2
Giralt, A.3
Gonzalez, F.J.4
Giralt, M.5
Mampel, T.6
Villarroya, F.7
-
39
-
-
47949111205
-
Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states
-
10.1124/mol.108.044826, 18467542
-
Muise ES, Azzolina B, Kuo DW, El-Sherbeini M, Tan Y, Yuan X, Mu J, Thompson JR, Berger JP, Wong KK. Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states. Mol Pharmacol 2008, 74:403-412. 10.1124/mol.108.044826, 18467542.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 403-412
-
-
Muise, E.S.1
Azzolina, B.2
Kuo, D.W.3
El-Sherbeini, M.4
Tan, Y.5
Yuan, X.6
Mu, J.7
Thompson, J.R.8
Berger, J.P.9
Wong, K.K.10
-
40
-
-
54849438574
-
FGF21 is an Akt-regulated myokine
-
10.1016/j.febslet.2008.10.021, 2604129, 18948104
-
Izumiya Y, Bina HA, Ouchi N, Akasaki Y, Kharitonenkov A, Walsh K. FGF21 is an Akt-regulated myokine. FEBS Lett 2008, 582:3805-3810. 10.1016/j.febslet.2008.10.021, 2604129, 18948104.
-
(2008)
FEBS Lett
, vol.582
, pp. 3805-3810
-
-
Izumiya, Y.1
Bina, H.A.2
Ouchi, N.3
Akasaki, Y.4
Kharitonenkov, A.5
Walsh, K.6
-
41
-
-
65749086156
-
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis
-
10.1002/mc.20494, 2712883, 19009564
-
Huang X, Yang C, Jin C, Luo Y, Wang F, McKeehan WL. Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. Mol Carcinog 2009, 48:553-562. 10.1002/mc.20494, 2712883, 19009564.
-
(2009)
Mol Carcinog
, vol.48
, pp. 553-562
-
-
Huang, X.1
Yang, C.2
Jin, C.3
Luo, Y.4
Wang, F.5
McKeehan, W.L.6
-
42
-
-
29244474612
-
Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis
-
10.1158/0008-5472.CAN-05-0716, 16357136
-
Wei C, Amos CI, Stephens LC, Campos I, Deng JM, Behringer RR, Rashid A, Frazier ML. Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis. Cancer Res 2005, 65:11297-11303. 10.1158/0008-5472.CAN-05-0716, 16357136.
-
(2005)
Cancer Res
, vol.65
, pp. 11297-11303
-
-
Wei, C.1
Amos, C.I.2
Stephens, L.C.3
Campos, I.4
Deng, J.M.5
Behringer, R.R.6
Rashid, A.7
Frazier, M.L.8
-
43
-
-
76549124517
-
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
-
10.1073/pnas.0911427107, 2824398, 20080689
-
Lu L, Li Y, Kim SM, Bossuyt W, Liu P, Qiu Q, Wang Y, Halder G, Finegold MJ, Lee JS, Johnson RL. Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci USA 2010, 107:1437-1442. 10.1073/pnas.0911427107, 2824398, 20080689.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1437-1442
-
-
Lu, L.1
Li, Y.2
Kim, S.M.3
Bossuyt, W.4
Liu, P.5
Qiu, Q.6
Wang, Y.7
Halder, G.8
Finegold, M.J.9
Lee, J.S.10
Johnson, R.L.11
-
44
-
-
77956944805
-
Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation
-
10.1074/jbc.M110.148288, 2943257, 20657013
-
Luo Y, Yang C, Lu W, Xie R, Jin C, Huang P, Wang F, McKeehan WL. Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation. J Biol Chem 2010, 285:30069-30078. 10.1074/jbc.M110.148288, 2943257, 20657013.
-
(2010)
J Biol Chem
, vol.285
, pp. 30069-30078
-
-
Luo, Y.1
Yang, C.2
Lu, W.3
Xie, R.4
Jin, C.5
Huang, P.6
Wang, F.7
McKeehan, W.L.8
-
45
-
-
79960947880
-
Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?
-
10.1371/journal.pone.0022976, 3148241, 21829679
-
Uebanso T, Taketani Y, Yamamoto H, Amo K, Ominami H, Arai H, Takei Y, Masuda M, Tanimura A, Harada N, Yamanaka-Okumura H, Takeda E. Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?. PLoS One 2011, 6:e22976. 10.1371/journal.pone.0022976, 3148241, 21829679.
-
(2011)
PLoS One
, vol.6
-
-
Uebanso, T.1
Taketani, Y.2
Yamamoto, H.3
Amo, K.4
Ominami, H.5
Arai, H.6
Takei, Y.7
Masuda, M.8
Tanimura, A.9
Harada, N.10
Yamanaka-Okumura, H.11
Takeda, E.12
-
46
-
-
0037102428
-
Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice
-
Nakau M, Miyoshi H, Seldin MF, Imamura M, Oshima M, Taketo MM. Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice. Cancer Res 2002, 62:4549-4553.
-
(2002)
Cancer Res
, vol.62
, pp. 4549-4553
-
-
Nakau, M.1
Miyoshi, H.2
Seldin, M.F.3
Imamura, M.4
Oshima, M.5
Taketo, M.M.6
-
47
-
-
84857694058
-
PPARgamma contributes to PKM2 and HK2 expression in fatty liver
-
3293420, 22334075
-
Panasyuk G, Espeillac C, Chauvin C, Pradelli LA, Horie Y, Suzuki A, Annicotte JS, Fajas L, Foretz M, Verdeguer F, Pontoglio M, Ferre P, Scoazec JY, Birnbaum MJ, Ricci JE, Pende M. PPARgamma contributes to PKM2 and HK2 expression in fatty liver. Nat Commun 2012, 3:672. 3293420, 22334075.
-
(2012)
Nat Commun
, vol.3
, pp. 672
-
-
Panasyuk, G.1
Espeillac, C.2
Chauvin, C.3
Pradelli, L.A.4
Horie, Y.5
Suzuki, A.6
Annicotte, J.S.7
Fajas, L.8
Foretz, M.9
Verdeguer, F.10
Pontoglio, M.11
Ferre, P.12
Scoazec, J.Y.13
Birnbaum, M.J.14
Ricci, J.E.15
Pende, M.16
-
48
-
-
0034685916
-
Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4
-
10.1074/jbc.275.20.15482, 10809780
-
Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL. Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4. J Biol Chem 2000, 275:15482-15489. 10.1074/jbc.275.20.15482, 10809780.
-
(2000)
J Biol Chem
, vol.275
, pp. 15482-15489
-
-
Yu, C.1
Wang, F.2
Kan, M.3
Jin, C.4
Jones, R.B.5
Weinstein, M.6
Deng, C.X.7
McKeehan, W.L.8
-
49
-
-
77957376253
-
Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse
-
10.1210/me.2010-0142, 2954642, 20667984
-
Fon Tacer K, Bookout AL, Ding X, Kurosu H, John GB, Wang L, Goetz R, Mohammadi M, Kuro-o M, Mangelsdorf DJ, Kliewer SA. Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse. Mol Endocrinol 2010, 24:2050-2064. 10.1210/me.2010-0142, 2954642, 20667984.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 2050-2064
-
-
Fon Tacer, K.1
Bookout, A.L.2
Ding, X.3
Kurosu, H.4
John, G.B.5
Wang, L.6
Goetz, R.7
Mohammadi, M.8
Kuro-o, M.9
Mangelsdorf, D.J.10
Kliewer, S.A.11
-
50
-
-
48349127924
-
The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man
-
10.1016/j.cmet.2008.06.014, 18680716
-
Galman C, Lundasen T, Kharitonenkov A, Bina HA, Eriksson M, Hafstrom I, Dahlin M, Amark P, Angelin B, Rudling M. The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man. Cell Metab 2008, 8:169-174. 10.1016/j.cmet.2008.06.014, 18680716.
-
(2008)
Cell Metab
, vol.8
, pp. 169-174
-
-
Galman, C.1
Lundasen, T.2
Kharitonenkov, A.3
Bina, H.A.4
Eriksson, M.5
Hafstrom, I.6
Dahlin, M.7
Amark, P.8
Angelin, B.9
Rudling, M.10
-
51
-
-
27844546989
-
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
-
10.1016/j.cmet.2005.09.001, 16213224
-
Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA. Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab 2005, 2:217-225. 10.1016/j.cmet.2005.09.001, 16213224.
-
(2005)
Cell Metab
, vol.2
, pp. 217-225
-
-
Inagaki, T.1
Choi, M.2
Moschetta, A.3
Peng, L.4
Cummins, C.L.5
McDonald, J.G.6
Luo, G.7
Jones, S.A.8
Goodwin, B.9
Richardson, J.A.10
Gerard, R.D.11
Repa, J.J.12
Mangelsdorf, D.J.13
Kliewer, S.A.14
-
52
-
-
34948821192
-
FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver
-
10.2337/db07-0648, 17664243
-
Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL. FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver. Diabetes 2007, 56:2501-2510. 10.2337/db07-0648, 17664243.
-
(2007)
Diabetes
, vol.56
, pp. 2501-2510
-
-
Huang, X.1
Yang, C.2
Luo, Y.3
Jin, C.4
Wang, F.5
McKeehan, W.L.6
-
53
-
-
33947192418
-
1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism
-
10.1016/j.jsbmb.2006.12.054, 17293108
-
Barthel TK, Mathern DR, Whitfield GK, Haussler CA, Hopper HA, Hsieh JC, Slater SA, Hsieh G, Kaczmarska M, Jurutka PW, Kolek OI, Ghishan FK, Haussler MR. 1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism. J Steroid Biochem Mol Biol 2007, 103:381-388. 10.1016/j.jsbmb.2006.12.054, 17293108.
-
(2007)
J Steroid Biochem Mol Biol
, vol.103
, pp. 381-388
-
-
Barthel, T.K.1
Mathern, D.R.2
Whitfield, G.K.3
Haussler, C.A.4
Hopper, H.A.5
Hsieh, J.C.6
Slater, S.A.7
Hsieh, G.8
Kaczmarska, M.9
Jurutka, P.W.10
Kolek, O.I.11
Ghishan, F.K.12
Haussler, M.R.13
-
54
-
-
84864105994
-
Activation of the Farnesoid X Receptor Induces Hepatic Expression and Secretion of Fibroblast Growth Factor 21
-
10.1074/jbc.M112.375907, 22661717
-
Cyphert HA, Ge X, Kohan AB, Salati LM, Zhang Y, Hillgartner FB. Activation of the Farnesoid X Receptor Induces Hepatic Expression and Secretion of Fibroblast Growth Factor 21. J Biol Chem 2012, 287:25123-25138. 10.1074/jbc.M112.375907, 22661717.
-
(2012)
J Biol Chem
, vol.287
, pp. 25123-25138
-
-
Cyphert, H.A.1
Ge, X.2
Kohan, A.B.3
Salati, L.M.4
Zhang, Y.5
Hillgartner, F.B.6
-
55
-
-
84862323517
-
Liver X receptor negatively regulates fibroblast growth factor 21 in the fatty liver induced by cholesterol-enriched diet
-
10.1016/j.jnutbio.2011.03.023, 21889884
-
Uebanso T, Taketani Y, Yamamoto H, Amo K, Tanaka S, Arai H, Takei Y, Masuda M, Yamanaka-Okumura H, Takeda E. Liver X receptor negatively regulates fibroblast growth factor 21 in the fatty liver induced by cholesterol-enriched diet. J Nutr Biochem 2012, 23:785-79055. 10.1016/j.jnutbio.2011.03.023, 21889884.
-
(2012)
J Nutr Biochem
, vol.23
, pp. 785-79055
-
-
Uebanso, T.1
Taketani, Y.2
Yamamoto, H.3
Amo, K.4
Tanaka, S.5
Arai, H.6
Takei, Y.7
Masuda, M.8
Yamanaka-Okumura, H.9
Takeda, E.10
-
56
-
-
0037462454
-
Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
-
10.1016/S0092-8674(03)00042-4, 12553907
-
Eferl R, Ricci R, Kenner L, Zenz R, David JP, Rath M, Wagner EF. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell 2003, 112:181-192. 10.1016/S0092-8674(03)00042-4, 12553907.
-
(2003)
Cell
, vol.112
, pp. 181-192
-
-
Eferl, R.1
Ricci, R.2
Kenner, L.3
Zenz, R.4
David, J.P.5
Rath, M.6
Wagner, E.F.7
-
57
-
-
74549217325
-
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation
-
10.1016/j.ccr.2009.12.048, 2841312, 20227042
-
He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T, Sieghart W, Peck-Radosavljevic M, Leffert HL, Karin M. Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. Cancer Cell 2010, 17:286-297. 10.1016/j.ccr.2009.12.048, 2841312, 20227042.
-
(2010)
Cancer Cell
, vol.17
, pp. 286-297
-
-
He, G.1
Yu, G.Y.2
Temkin, V.3
Ogata, H.4
Kuntzen, C.5
Sakurai, T.6
Sieghart, W.7
Peck-Radosavljevic, M.8
Leffert, H.L.9
Karin, M.10
-
58
-
-
43549110007
-
FGF21 attenuates lipolysis in human adipocytes - a possible link to improved insulin sensitivity
-
10.1016/j.febslet.2008.04.038, 18460341
-
Arner P, Pettersson A, Mitchell PJ, Dunbar JD, Kharitonenkov A, Ryden M. FGF21 attenuates lipolysis in human adipocytes - a possible link to improved insulin sensitivity. FEBS Lett 2008, 582:1725-1730. 10.1016/j.febslet.2008.04.038, 18460341.
-
(2008)
FEBS Lett
, vol.582
, pp. 1725-1730
-
-
Arner, P.1
Pettersson, A.2
Mitchell, P.J.3
Dunbar, J.D.4
Kharitonenkov, A.5
Ryden, M.6
-
59
-
-
70349472910
-
Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice
-
10.1016/j.febslet.2009.09.012, 19751733
-
Li X, Ge H, Weiszmann J, Hecht R, Li YS, Veniant MM, Xu J, Wu X, Lindberg R, Li Y. Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice. FEBS Lett 2009, 583:3230-3234. 10.1016/j.febslet.2009.09.012, 19751733.
-
(2009)
FEBS Lett
, vol.583
, pp. 3230-3234
-
-
Li, X.1
Ge, H.2
Weiszmann, J.3
Hecht, R.4
Li, Y.S.5
Veniant, M.M.6
Xu, J.7
Wu, X.8
Lindberg, R.9
Li, Y.10
-
60
-
-
67649823642
-
FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
-
10.1073/pnas.0904187106, 2705613, 19541642
-
Potthoff MJ, Inagaki T, Satapati S, Ding X, He T, Goetz R, Mohammadi M, Finck BN, Mangelsdorf DJ, Kliewer SA, Burgess SC. FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response. Proc Natl Acad Sci USA 2009, 106:10853-10858. 10.1073/pnas.0904187106, 2705613, 19541642.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 10853-10858
-
-
Potthoff, M.J.1
Inagaki, T.2
Satapati, S.3
Ding, X.4
He, T.5
Goetz, R.6
Mohammadi, M.7
Finck, B.N.8
Mangelsdorf, D.J.9
Kliewer, S.A.10
Burgess, S.C.11
-
61
-
-
80055115165
-
FGF10 and FGF21 as Regulators in Adipocyte Development and Metabolism
-
10.2174/187153011797881166, 21696361
-
Ohta H, Konishi M, Itoh N. FGF10 and FGF21 as Regulators in Adipocyte Development and Metabolism. Endocr Metab Immune Disord Drug Targets 2011, 11:302-309. 10.2174/187153011797881166, 21696361.
-
(2011)
Endocr Metab Immune Disord Drug Targets
, vol.11
, pp. 302-309
-
-
Ohta, H.1
Konishi, M.2
Itoh, N.3
-
62
-
-
41649109108
-
BetaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c
-
10.1210/me.2007-0313, 18187602
-
Suzuki M, Uehara Y, Motomura-Matsuzaka K, Oki J, Koyama Y, Kimura M, Asada M, Komi-Kuramochi A, Oka S, Imamura T. betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c. Mol Endocrinol 2008, 22:1006-1014. 10.1210/me.2007-0313, 18187602.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1006-1014
-
-
Suzuki, M.1
Uehara, Y.2
Motomura-Matsuzaka, K.3
Oki, J.4
Koyama, Y.5
Kimura, M.6
Asada, M.7
Komi-Kuramochi, A.8
Oka, S.9
Imamura, T.10
-
63
-
-
84870568785
-
Circulating fibroblast growth factors as metabolic regulators-a critical appraisal
-
10.1016/j.cmet.2012.11.001, 23217254
-
Angelin B, Larsson TE, Rudling M. Circulating fibroblast growth factors as metabolic regulators-a critical appraisal. Cell Metab 2012, 16:693-705. 10.1016/j.cmet.2012.11.001, 23217254.
-
(2012)
Cell Metab
, vol.16
, pp. 693-705
-
-
Angelin, B.1
Larsson, T.E.2
Rudling, M.3
-
64
-
-
79954458265
-
Biomarkers of liver fibrosis
-
10.1111/j.1440-1746.2010.06612.x, 21198831
-
Adams LA. Biomarkers of liver fibrosis. J Gastroenterol Hepatol 2011, 26:802-809. 10.1111/j.1440-1746.2010.06612.x, 21198831.
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 802-809
-
-
Adams, L.A.1
|