Human U6 promoter drives stronger shRNA activity than its schistosome orthologue in Schistosoma mansoni and human fibrosarcoma cells

Transgenic Research

Volumn 21, Issue 3, 2012, Pages 511-521

  Duvoisin, Raphaël ^a,b   Ayuk, Mary A ^a,c   Rinaldi, Gabriel ^a,d   Suttiprapa, Sutas ^a   Mann, Victoria H ^a   Lee, Clarence M ^c   Harris, Nicola ^b   Brindley, Paul J ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^b EPFL   (Switzerland)

^c HOWARD UNIVERSITY   (United States)

^d DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

Author keywords

Firefly luciferase; Murine leukemia virus; piggyBac transposon; Promoter; RNA interference; Schistosoma mansoni; Schistosome; Short hairpin RNA; U6 gene

Indexed keywords

FIREFLY LUCIFERASE; MESSENGER RNA; SMALL INTERFERING RNA; SMALL NUCLEAR RIBONUCLEOPROTEIN;

ANIMAL; ARTICLE; COMPARATIVE STUDY; ENZYME ACTIVATION; FIBROSARCOMA; GENE; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MURINE LEUKEMIA VIRUS; PLASMID; PROMOTER REGION; REPORTER GENE; RNA INTERFERENCE; SCHISTOSOMA MANSONI; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; ENZYME ACTIVATION; FIBROSARCOMA; GENES, HELMINTH; GENES, REPORTER; GENETIC VECTORS; HUMANS; LEUKEMIA VIRUS, MURINE; LUCIFERASES, FIREFLY; PLASMIDS; PROMOTER REGIONS, GENETIC; RIBONUCLEOPROTEIN, U4-U6 SMALL NUCLEAR; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SCHISTOSOMA MANSONI; TRANSFECTION;

MURINE LEUKEMIA VIRUS; PLATYHELMINTHES; SCHISTOSOMA; SCHISTOSOMA MANSONI; SCHISTOSOMATIDAE; TREMATODA;

EID: 84860881567     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-011-9548-0     Document Type: Article

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