A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility

PLoS Neglected Tropical Diseases

Volumn 4, Issue 11, 2010, Pages

  Smout, Michael J ^a   Kotze, Andrew C ^b   Mccarthy, James S ^c   Loukas, Alex ^a  

^a JAMES COOK UNIVERSITY   (Australia)

^b CSIRO   (Australia)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; IVERMECTIN; LEVAMISOLE; PRAZIQUANTEL; TIABENDAZOLE;

ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; ANTHELMINTIC ACTIVITY; ARTICLE; AUTOMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RESEARCH; DRUG RESISTANCE; DRUG SENSITIVITY; FEMALE; GENE SILENCING; HAEMONCHOSIS; HAEMONCHUS CONTORTUS; HATCHING; HIGH THROUGHPUT SCREENING; HOOKWORM; IC 50; LARVA; MALE; NONHUMAN; PARASITE MIGRATION; PHENOTYPE; QUANTITATIVE ANALYSIS; RECOMMENDED DRUG DOSE; SHEEP; STRONGYLOIDES RATTI; TREMATODE; ANIMAL; ANIMAL PARASITOSIS; DOG; DOG DISEASE; DRUG EFFECT; DRUG SCREENING; EVALUATION; HELMINTH; HELMINTHIASIS; HUMAN; METHODOLOGY; MOUSE; PARASITOLOGY; PHYSIOLOGY; SHEEP DISEASE;

ANIMALS; ANTHELMINTICS; DOG DISEASES; DOGS; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE; HELMINTHIASIS; HELMINTHIASIS, ANIMAL; HELMINTHS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MICE; PARASITIC SENSITIVITY TESTS; SHEEP; SHEEP DISEASES;

EID: 78649779750     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pntd.0000885     Document Type: Article

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